A permease-oxidase complex involved in high-affinity iron uptake in yeast.

Basic local alignment search tool

Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669

Ferrozine---a new spectrophotometric reagent for iron

Stookey, L. L. (1970) · Analytical Chemistry · doi:10.1021/ac60289a016 · Cited by 4,712

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

Bull, P. C., Thomas, G. R., Rommens, J. M., Forbes, J., & Cox, D. W. (1993) · Nature Genetics · doi:10.1038/ng1293-327 · Cited by 1,939

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

Tanzi, R. E., Petrukhin, K. E., Чернов, И. П., Pellequer, J., Wasco, W., Ross, B., Romano, D., Parano, E., Pavone, P., Brzustowicz, L. M., et al. (1993) · Nature Genetics · doi:10.1038/ng1293-344 · Cited by 1,367

High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men

Salonen, J. T., Nyyssönen, K., Korpela, H., Tuomilehto, J., Seppänen, R., & Salonen, R. (1992) · Circulation · doi:10.1161/01.cir.86.3.803 · Cited by 1,284

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

Rose, M. D., Novick, P., Thomas, J. H., Botstein, D., & Fink, G. R. (1987) · Gene · doi:10.1016/0378-1119(87)90232-0 · Cited by 1,126

Altered Brain Metabolism of Iron as a Cause of Neurodegenerative Diseases?

Gerlach, M., Ben‐Shachar, D., Riederer, P. F., & Youdim, M. B. H. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63030793.x · Cited by 704

The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum.

Osaki, S., Johnson, D. A., & Frieden, E. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96527-0 · Cited by 679

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.

Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., & Kaplan, J. (1994) · Cell · doi:10.1016/0092-8674(94)90346-8 · Cited by 670

Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport

Dancis, A., Yuan, D. S., Haile, D., Askwith, C., Eide, D., Moehle, C., Kaplan, J., & Klausner, R. D. (1994) · Cell · doi:10.1016/0092-8674(94)90345-x · Cited by 659

Ferric uptake regulation protein acts as a repressor, employing iron (II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli

Bagg, A., & Neilands, J. B. (1987) · Biochemistry · doi:10.1021/bi00391a039 · Cited by 593

Aceruloplasminemia: molecular characterization of this disorder of iron metabolism.

Harris, Z. L., Takahashi, Y., Miyajima, H., Serizawa, M., MacGillivray, R. T., & Gitlin, J. D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.2539 · Cited by 558

Metalloenzymes, Structural Motifs, and Inorganic Models

Karlin, K. D. (1993) · Science · doi:10.1126/science.7688141 · Cited by 553

Isolation and Characterization of a Human Liver cDNA as a Candidate Gene for Wilson Disease

Yamaguchi, Y., Heiny, M. E., & Gitlin, J. D. (1993) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1993.2471 · Cited by 508

[35] Epitope tagging and protein surveillance

Kolodziej, P. A., & Young, R. A. (1991) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(91)94038-e · Cited by 500

IRON ABSORPTION AND TRANSPORT IN MICROORGANISMS

Neilands, J. B. (1981) · Annual Review of Nutrition · doi:10.1146/annurev.nu.01.070181.000331 · Cited by 477

A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans

Yoshida, K., Furihata, K., Takeda, S., Nakamura, A., Yamamoto, K., Morita, H., Hiyamuta, S., Ikeda, S.-I., Shimizu, N., & Yanagisawa, N. (1995) · Nature Genetics · doi:10.1038/ng0395-267 · Cited by 463

Characterization of the ferrous iron uptake system of Escherichia coli

Kammler, M., Schön, C., & Hantke, K. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.19.6212-6219.1993 · Cited by 460

Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions

Smith, C., Mitchinson, M. J., Aruoma, O. I., & Halliwell, B. (1992) · Biochemical Journal · doi:10.1042/bj2860901 · Cited by 455

The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake.

Yuan, D., Stearman, R. S., Dancis, A., Dunn, T. M., Beeler, T., & Klausner, R. D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.2632 · Cited by 436

The role of ceruloplasmin in iron metabolism.

Roeser, H. P., Lee, G. R., Nacht, S., & Cartwright, G. E. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106460 · Cited by 365

AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae.

Yamaguchi‐Iwai, Y., Dancis, A., & Klausner, R. D. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07106.x · Cited by 358

Ferric reductase of Saccharomyces cerevisiae: molecular characterization, role in iron uptake, and transcriptional control by iron.

Dancis, A., Roman, D. G., Anderson, G. J., Hinnebusch, A. G., & Klausner, R. D. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.9.3869 · Cited by 358

[44] Methods for studying the yeast vacuole

Roberts, C. J., Raymond, C. K., Yamashiro, C. T., & Stevens, T. H. (1991) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(91)94047-g · Cited by 347

Increased iron‐related MRI contrast in the substantia nigra in Parkinson's disease

Gorell, J. M., Ordidge, R. J., Brown, G. G., Deniau, J.-C., Buderer, N. M. F., & Helpern, J. A. (1995) · Neurology · doi:10.1212/wnl.45.6.1138 · Cited by 324

The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae

Dix, D., Bridgham, J. T., Broderius, M. A., Byersdorfer, C. A., & Eide, D. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47163-3 · Cited by 320

Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degeneration

Miyajima, H., Nishimura, Y., Mimguchi, K., Sakamoto, M., Shimizu, T., & Honda, N. (1987) · Neurology · doi:10.1212/wnl.37.5.761 · Cited by 295

Long Term Results of Venesection Therapy in Idiopathic Haemochromatosis

Bomford, A. B., & Williams, R. L. (1976) · QJM · doi:10.1093/oxfordjournals.qjmed.a067484 · Cited by 270

Hallervorden-Spatz Syndrome

Dooling, E. C., Schoene, W. C., & Richardson, E. P. (1974) · Archives of Neurology · doi:10.1001/archneur.1974.00490310072012 · Cited by 269

Iron metabolism in copper-deficient swine

Lee, G. R., Nacht, S., Lukens, J. N., & Cartwright, G. E. (1968) · Journal of Clinical Investigation · doi:10.1172/jci105891 · Cited by 259

The FET3 Gene Product Required for High Affinity Iron Transport in Yeast Is a Cell Surface Ferroxidase

Silva, D. M. D., Askwith, C. C., Eide, D. J., & Kaplan, J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.3.1098 · Cited by 246

Two Distinctly Regulated Genes Are Required for Ferric Reduction, the First Step of Iron Uptake in Saccharomyces cerevisiae

Georgatsou, E., & Alexandraki, D. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.5.3065-3073.1994 · Cited by 233

The Role of the L-Chain in Ferritin Iron Incorporation

Levi, S., Santambrogio, P., Cozzi, A., Rovida, E., Corsi, B., Tamborini, E., Spada, S., Albertini, A., & Arosio, P. (1994) · Journal of Molecular Biology · doi:10.1006/jmbi.1994.1325 · Cited by 180

Sequence, mapping and disruption of CCC2, a gene that cross‐complements the Ca2+‐sensitive phenotype of csg1 mutants and encodes a P‐type ATPase belonging to the Cu2+‐ATPase subfamily

Fu, D., Beeler, T., & Dunn, T. M. (1995) · Yeast · doi:10.1002/yea.320110310 · Cited by 168

Iron Uptake by the Yeast Saccharomyces cerevisiae: Involvement of a Reduction Step

Lesuisse, E., Raguzzi, F., & Crichton, R. R. (1987) · Microbiology · doi:10.1099/00221287-133-11-3229 · Cited by 157

High Resolution Crystal Structures of Amphibian Red-Cell L Ferritin: Potential Roles for Structural Plasticity and Solvation in Function

Trikha, J., Theil, E. C., & Allewell, N. M. (1995) · Journal of Molecular Biology · doi:10.1006/jmbi.1995.0274 · Cited by 133

The fission yeast ferric reductase gene frp1+ is required for ferric iron uptake and encodes a protein that is homologous to the gp91-phox subunit of the human NADPH phagocyte oxidoreductase.

Roman, D. G., Dancis, A., Anderson, G. J., & Klausner, R. D. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.7.4342 · Cited by 128

Plants can utilize iron form Fe‐N,N'‐di‐(2‐hydroxybenzoyl)‐ethylenediamine‐N,N'‐diacetic acid, a ferric chelate with 106greater formation constant than Fe‐EDDHA.

Chaney, R. L. (1988) · Journal of Plant Nutrition · doi:10.1080/01904168809363867 · Cited by 108

[16] Gene overexpression in studies of Saccharomyces cerevisiae

Rine, J. (1991) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(91)94019-9 · Cited by 102

Function of integrin in duodenal mucosal uptake of iron

Conrad, M., Jn, U., Peterson, R., Moore, E., & Harper, K. (1993) · Blood · doi:10.1182/blood.v81.2.517.517 · Cited by 77

A Cellular Stress Model for the Sequestration of Redox‐Active Glial Iron in the Aging and Degenerating Nervous System

Wang, X., Manganaro, F., & Schipper, H. M. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64041868.x · Cited by 46

The H(+)-ATPase from reticulocyte endosomes reconstituted into liposomes acts as an iron transporter.

Li, C. Y., Watkins, J. A., & Glass, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34053-x · Cited by 34

Computed tomography in Hallervorden‐Spatz disease

Dooling, E. C., Richardson, E. P., & Davis, K. R. (1980) · Neurology · doi:10.1212/wnl.30.10.1128 · Cited by 27

Iron metabolism in Wilson's disease

OʼReilly, S., Pollycove, M., & Bank, W. (1968) · Neurology · doi:10.1212/wnl.18.7.634 · Cited by 11

Roles of iron in infection and neoplasia.

Weinberg, E. D. (1986) · PubMed · Cited by 10

Multicopper oxidases and oxygenases

Solomon, E. I., Sundaram, U. M., & Machonkin, T. E. (1996) · Chemical Reviews · doi:10.1021/cr950046o · Cited by 3,664

Siderophore-Based Iron Acquisition and Pathogen Control

Miethke, M., & Marahiel, M. A. (2007) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00012-07 · Cited by 1,774

Copper Active Sites in Biology

Solomon, E. I., Heppner, D. E., Johnston, E. M., Ginsbach, J. W., Cirera, J., Qayyum, M. F., Kieber‐Emmons, M. T., Kjaergaard, C. H., Hadt, R. G., & Tian, L. (2014) · Chemical Reviews · doi:10.1021/cr400327t · Cited by 1,803

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., et al. (2000) · Nature · doi:10.1038/35001596 · Cited by 1,667

The ZIP family of metal transporters

Guerinot, M. L. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00138-3 · Cited by 1,200

The Primary Genes of the High-Affinity Iron Transport System in the Yeast Saccharomyces Cerevisiae and the Effects on This System of the Enviromental Factors

Hai, Z. (2000) · Journal of Shanxi Teachers University

Site-directed Mutagenesis of the Yeast Multicopper Oxidase Fet3p

Askwith, C. C., & Kaplan, J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.35.22415 · Cited by 62

The yeast FET5 gene encodes a FET3 -related multicopper oxidase implicated in iron transport

Spizzo, T., Byersdorfer, C. A., Duesterhoeft, S., & Eide, D. J. (1997) · Molecular and General Genetics MGG · doi:10.1007/pl00008615 · Cited by 80

The Ftr1p iron permease in the yeast plasma membrane: orientation, topology and structure-function relationships

Severance, S., CHAKRABORTY, S., & Kosman, D. J. (2004) · Biochemical Journal · doi:10.1042/bj20031921 · Cited by 85

An engineered bifunctional high affinity iron uptake protein in the yeast plasma membrane

Kwok, E. Y., Stoj, C. S., Severance, S., & Kosman, D. J. (2006) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2005.11.015 · Cited by 7