The DOI matches its Crossref record; 87 of the 91 references it cites were found in a registry or an index.
Death Receptors: Signaling and Modulation
Abstract
REVIEW Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors, on their surface. Death receptors detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery.
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“Extrinsic apoptosis is an RCD modality initiated by perturbations of the extracellular microenvironment [265–268].”
From Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018. (2018) · cites this paper as [265]
Citations
Cites
Thornberry, N. A., & Lazebnik, Y. A. (1998) · Science · doi:10.1126/science.281.5381.1312 · Cited by 6,857
Apoptosis in the Pathogenesis and Treatment of Disease
Thompson, C. B. (1995) · Science · doi:10.1126/science.7878464 · Cited by 6,524
The Bcl-2 Protein Family: Arbiters of Cell Survival
Adams, J. M., & Cory, S. (1998) · Science · doi:10.1126/science.281.5381.1322 · Cited by 5,334
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M.-S., Lüthy, R., Nguyen, H. Q., Wooden, S., Bennett, L., Boone, T., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80209-3 · Cited by 5,130
Zou, H., Henzel, W. J., Liu, X., Lutschg, A., & Wang, X. (1997) · Cell · doi:10.1016/s0092-8674(00)80501-2 · Cited by 3,145
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
Beg, A. A., & Baltimore, D. (1996) · Science · doi:10.1126/science.274.5288.782 · Cited by 3,047
Identification and characterization of a new member of the TNF family that induces apoptosis
Wiley, S. R., Schooley, K., Smolak, P. J., Din, W. S., Huang, C.-P., Nicholl, J. K., Sutherland, G. R., Smith, T. D., Rauch, C., Smith, C. A., et al. (1995) · Immunity · doi:10.1016/1074-7613(95)90057-8 · Cited by 2,900
Programmed Cell Death in Animal Development
Jacobson, M. D., Weil, M., & RAFF, M. C. (1997) · Cell · doi:10.1016/s0092-8674(00)81873-5 · Cited by 2,685
Mechanisms and Genes of Cellular Suicide
Steller, H. (1995) · Science · doi:10.1126/science.7878463 · Cited by 2,469
Chinnaiyan, A. M., O'Rourke, K., Tewari, M., & Dixit, V. M. (1995) · Cell · doi:10.1016/0092-8674(95)90071-3 · Cited by 2,431
Self-citation
Research works printed but not linked: 10
- Boise L. H., Thompson C. B., ibid. 274, 67 (1996);
- Winoto A., ibid. 9, 365 (1997).
- Nagata S., ibid. 88, 355 (1997).
- Pan G., et al., ibid. 277, 815 (1997).
- Rothe M., Pan M. G., Henzel W. J., Ayres T. M., Goeddel D. V., ibid. 83, 1243 (1995).
- Kelliher M., et al., ibid. 8, 297 (1998).
- Ahmad M., et al., Cancer Res. 57, 615 (1997).
- M. J. Martinez-Lorenzo et al. Eur. J. Immunol. in press.
- Jeramias I., Herr I., Boehler T., Debatin K. M., ibid. 28, 143 (1998).
- Lacey D. L., et al., ibid. 93, 165 (1998).
Cited by
Sorted by citations
Apoptosis: A Review of Programmed Cell Death
Elmore, S. (2007) · Toxicologic Pathology · doi:10.1080/01926230701320337 · Cited by 13,853
Hengartner, M. O. (2000) · Nature · doi:10.1038/35037710 · Cited by 5,779
Thornberry, N. A., & Lazebnik, Y. A. (1998) · Science · doi:10.1126/science.281.5381.1312 · Cited by 6,857
Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680
Self-citationAkt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., & Greenberg, M. E. (1999) · Cell · doi:10.1016/s0092-8674(00)80595-4 · Cited by 5,594
Metadata
- Authors
- Ashkenazi, A., & Dixit, V. M.
- Affiliations
- Genentech (US)
- Venue
- Science
- Published
- 1998-08-28
- Volume
- 281
- Issue
- 5381
- Pages
- 1305-1308
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2025128734
- Cited by
- 5,866
- References
- 91
- Citations by year
- 2026: 42 · 2025: 63 · 2024: 61 · 2023: 87 · 2022: 84 · 2021: 96 · 2020: 116 · 2019: 116 · 2018: 142 · 2017: 126 · 2016: 158 · 2015: 177 · 2014: 171 · 2013: 196 · 2012: 191
- FWCI
- 26.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Social Sciences › Anthropology › Death, Funerary Practices, and Mourning
- Keywords
- death receptors, apoptosis, signal transduction, cell number regulation, programmed cell death
- MeSH terms
- Animals, Humans, Neoplasms, Receptors, Cell Surface, Signal Transduction, Antigens, CD, Apoptosis, Receptors, Tumor Necrosis Factor, fas Receptor, Receptors, Tumor Necrosis Factor, Type I, Receptors, Tumor Necrosis Factor, Member 25, Receptors, TNF-Related Apoptosis-Inducing Ligand
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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