The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Experimental Evolution of Parasites
Abstract
Serial passage experiments are a form of experimental evolution that is frequently used in applied sciences; for example, in vaccine development. During these experiments, molecular and phenotypic evolution can be monitored in real time, providing insights into the causes and consequences of parasite evolution. Within-host competition generally drives an increase in a parasite's virulence in a new host, whereas the parasite becomes avirulent to its former host, indicating a trade-off between parasite fitnesses on different hosts. Understanding why parasite virulence seldom escalates similarly in natural populations could help us to manage virulence and deal with emerging diseases.
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Citations
Cites
Coevolution of hosts and parasites
Anderson, R. M., & May, R. M. (1982) · Parasitology · doi:10.1017/s0031182000055360 · Cited by 1,630
Sex versus Non-Sex versus Parasite
Hamilton, W. D. (1980) · Oikos · doi:10.2307/3544435 · Cited by 1,368
Accelerated evolution and Muller’s Rachet in endosymbiotic bacteria
Moran, N. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.7.2873 · Cited by 1,017
SKEPTICISM TOWARDS SANTA ROSALIA, OR WHY ARE THERE SO FEW KINDS OF ANIMALS?
Felsenstein, J. (1981) · Evolution · doi:10.1111/j.1558-5646.1981.tb04864.x · Cited by 1,000
High Mutation Frequencies Among Escherichia coli and Salmonella Pathogens
LeClerc, J. E., Li, B., Payne, W. L., & Cebula, T. A. (1996) · Science · doi:10.1126/science.274.5290.1208 · Cited by 817
Smith, J. M. (1966) · The American Naturalist · doi:10.1086/282457 · Cited by 758
The Dawn of Darwinian Medicine
Williams, G. C., & Nesse, R. M. (1991) · The Quarterly Review of Biology · doi:10.1086/417048 · Cited by 745
Coinfection and the evolution of parasite virulence
(1995) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.1995.0138 · Cited by 729
Evolution of Infectious Disease
Ewald, P. W. (1994) · doi:10.1093/oso/9780195060584.001.0001 · Cited by 714
Superinfection and the evolution of parasite virulence
(1994) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.1994.0012 · Cited by 592
Cited by
Evolution Experiments with Microorganisms: The Dynamics and Genetic Bases of Adaptation
Elena, S. F., & Lenski, R. E. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1088 · Cited by 1,386
Virulence evolution and the trade‐off hypothesis: history, current state of affairs and the future
ALIZON, S., HURFORD, A., MIDEO, N., & VAN BAALEN, M. (2009) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2008.01658.x · Cited by 932
Biological and biomedical implications of the co-evolution of pathogens and their hosts
Woolhouse, M. E. J., Webster, J. P., Domingo, E., Charlesworth, B., & Levin, B. R. (2002) · Nature Genetics · doi:10.1038/ng1202-569 · Cited by 869
Kawecki, T. J., Lenski, R. E., Ebert, D., Hollis, B., Olivieri, I., & Whitlock, M. C. (2012) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2012.06.001 · Cited by 807
Self-citationThe Ecology of Genetically Diverse Infections
Read, A. F., & Taylor, L. H. (2001) · Science · doi:10.1126/science.1059410 · Cited by 639
Metadata
- Authors
- Ebert, D.
- Venue
- Science
- Published
- 1998-11-20
- Volume
- 282
- Issue
- 5393
- Pages
- 1432-1436
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2116067373
- Cited by
- 566
- References
- 46
- FWCI
- 9.10
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
