The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems
Abstract
Specific σ binding sites have been identified in the mammalian brain and lymphoid tissue. In this study, certain gonadal and adrenal steroids, particularly progesterone, were found to inhibit σ receptor binding in homogenates of brain and spleen. The findings suggest that steroids are naturally occurring ligands for σ receptors and raise the possibility that these sites mediate some aspects of steroid-induced mental disturbances and alterations in immune functions.
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Cites
Yung-Chi, C., & Prusoff, W. H. (1973) · Biochemical Pharmacology · doi:10.1016/0006-2952(73)90196-2 · Cited by 12,922
Martin, W. R., Eades, C. G., Thompson, J. A., Huppler, R. E., & Gilbert, P. E. (1976) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)30536-7 · Cited by 2,992
Cited by
Hayashi, T., & Su, T.-P. (2007) · Cell · doi:10.1016/j.cell.2007.08.036 · Cited by 1,826
Self-citationMAM: more than just a housekeeper
Hayashi, T., Rizzuto, R., Hajnoczky, G., & Su, T.-P. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.12.002 · Cited by 787
Self-citationEffects of stress on the immune system
Khansari, D. N., Murgo, A. J., & Faith, R. E. (1990) · Immunology Today · doi:10.1016/0167-5699(90)90069-l · Cited by 668
The pharmacology of sigma-1 receptors.
Maurice, T., & Su, T.-P. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.07.001 · Cited by 654
Self-citationThe Hallucinogen N,N -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator
Fontanilla, D., Johannessen, M., Hajipour, A. R., Cozzi, N. V., Jackson, M. B., & Ruoho, A. E. (2009) · Science · doi:10.1126/science.1166127 · Cited by 535
Metadata
- Authors
- Su, T.-P., London, E. D., & Jaffe, J. H.
- Venue
- Science
- Published
- 1988-04-08
- Volume
- 240
- Issue
- 4849
- Pages
- 219-221
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2003532781
- Cited by
- 546
- References
- 2
- FWCI
- 7.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- Su, T.-P., London, E. D., & Jaffe, J. H. (1988). Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems. Science. https://doi.org/10.1126/science.2832949
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
