The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Patterning of the Zebrafish Retina by a Wave of Sonic Hedgehog Activity
Abstract
The Drosophila retina is patterned by a morphogenetic wave driven by the Hedgehog signaling protein. Hedgehog, secreted by the first neurons, induces neuronal differentiation and hedgehog expression in nearby uncommitted cells, thereby propagating the wave. Evidence is presented here that the zebrafish Hedgehog homolog, Sonic Hedgehog, is also expressed in the first retinal neurons, and that Sonic Hedgehog drives a wave of neurogenesis across the retina, strikingly similar to the wave in Drosophila . The conservation of this patterning mechanism is unexpected, given the highly divergent structures of vertebrate and invertebrate eyes, and supports a common evolutionary origin of the animal visual system.
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Cites
Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling
Cooper, M. K., Porter, J. A., Young, K. E., & Beachy, P. A. (1998) · Science · doi:10.1126/science.280.5369.1603 · Cited by 848
Pax 6: mastering eye morphogenesis and eye evolution
Gehring, W. J., & Ikeo, K. (1999) · Trends in Genetics · doi:10.1016/s0168-9525(99)01776-x · Cited by 758
Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish
Schauerte, H. E., Eeden, F. J. M. V., Fricke, C., Odenthal, J., Strähle, U., & Haffter, P. (1998) · Development · doi:10.1242/dev.125.15.2983 · Cited by 349
Cited by
1 Developmental roles and clinical significance of Hedgehog signaling
McMahon, A. P., Ingham, P. W., & Tabin, C. J. (2003) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)53002-2 · Cited by 772
Gahtan, E., Tanger, P., & Baier, H. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2678-05.2005 · Cited by 350
Hedgehog signalling controls eye degeneration in blind cavefish
Yamamoto, Y., Stock, D. W., & Jeffery, W. R. (2004) · Nature · doi:10.1038/nature02864 · Cited by 274
Bharti, K., Nguyen, M. T., Skuntz, S., Bertuzzi, S., & Arnheiter, H. (2006) · Pigment Cell Research · doi:10.1111/j.1600-0749.2006.00318.x · Cited by 237
Visuomotor behaviors in larval zebrafish after GFP-guided laser ablation of the optic tectum
Roeser, T., & Baier, H. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-09-03726.2003 · Cited by 222
Metadata
- Authors
- Neumann, C. J., & Nuesslein-Volhard, C.
- Venue
- Science
- Published
- 2000-09-22
- Volume
- 289
- Issue
- 5487
- Pages
- 2137-2139
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1963804798
- Cited by
- 385
- References
- 3
- FWCI
- 7.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Neumann, C. J., & Nuesslein-Volhard, C. (2000). Patterning of the Zebrafish Retina by a Wave of Sonic Hedgehog Activity. Science. https://doi.org/10.1126/science.289.5487.2137
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