The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor
Abstract
The transforming protein of a primate sarcoma virus and a platelet-derived growth factor are derived from the same or closely related cellular genes. This conclusion is based on the demonstration of extensive sequence similarity between the transforming protein derived from the simian sarcoma virus onc gene, v- sis , and a human platelet-derived growth factor. The mechanism by which v- sis transforms cells could involve the constitutive expression of a protein with functions similar or identical to those of a factor active transiently during normal cell growth.
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Cites
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Use of suramin in treatment of prostatic carcinoma refractory to conventional hormonal manipulation
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Metadata
- Authors
- Doolittle, R. F., Hunkapiller, M. W., Hood, L. E., Devare, S. G., Robbins, K. C., Aaronson, S. A., & Antoniades, H. N.
- Venue
- Science
- Published
- 1983-07-15
- Volume
- 221
- Issue
- 4607
- Pages
- 275-277
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1982020713
- Cited by
- 1,536
- References
- 1
- FWCI
- 72.67
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.