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Cited by 3,052

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

Coyle, Joseph T., Price, Donald L., DeLong, Mahlon R.·1983·Science

Abstract

Great emphasis is being placed on identification of neurotransmitter systems involved in the symptomatic manifestations of neurological and psychiatric disorders. In the case of Alzheimer's disease, which now seems to be one of the most common causes of mental deterioration in the elderly, compelling evidence has been developed that acetylcholine-releasing neurons, whose cell bodies lie in the basal forebrain, selectively degenerate. These cholinergic neurons provide widespread innervation of the cerebral cortex and related structures and appear to play an important role in cognitive functions, especially memory. These advances reflect a close interaction between experimental and clinical neuroscientists in which information derived from basic neurobiology is rapidly utilized to analyze disorders of the human brain.

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Crossref · 10.1126/science.6338589

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Metadata

Authors
Coyle, J. T., Price, D. L., & DeLong, M. R.
Venue
Science
Published
1983-03-11
Volume
219
Issue
4589
Pages
1184-1190
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2021280501
Cited by
3,052
References
8
FWCI
124.84
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation. https://app.cochat.ai/papers/10.1126/science.6338589
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Coyle, J. T., Price, D. L., & DeLong, M. R. (1983). Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation. Science. https://doi.org/10.1126/science.6338589

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.