Isolation of New Ribozymes from a Large Pool of Random Sequences

Bartel, David P., Szostak, Jack W.·1993·Science
DOI 10.1126/science.7690155

Cited by (901)

Items 601–700 of 901

  1. Origin & influence of autocatalytic reaction networks at the advent of the RNA world
    Stephen A. Zorc, Raktim N. Roy · 2024 · RNA Biology
  2. DeNAno: Selectable deoxyribonucleic acid nanoparticle libraries
    Jason Steiner, Marta Sartor, Ana Beatriz Sánchez, Davorka Messmer, Anna Freed, Sadik C. Esener, Bradley T. Messmer · 2009 · Journal of Biotechnology
  3. RNA Polymerase Ribozyme That Recognizes the Template–Primer Complex through Tertiary Interactions
    Ankana Kakoti, Gerald F. Joyce · 2023 · Biochemistry
  4. Landmarks in the Evolution of (t)-RNAs from the Origin of Life up to Their Present Role in Human Cognition
    Darko Balke, Andreas Walter Kuss, Sabine Müller · 2015 · Life
  5. A combinatorial method to isolate short ribozymes from complex ribozyme libraries
    Joshua T. Arriola, Ulrich F. Müller · 2020 · Nucleic Acids Research
  6. Natural Selection beyond Life? A Workshop Report
    Sylvain Charlat, André Ariew, Pierrick Bourrat, María J. Ferreira Ruiz, Thomas Heams, Philippe Huneman, Sandeep Krishna, Michael Lachmann, Nicolas Lartillot, Louis d’Hendecourt et al. · 2021 · Life
  7. Active centrum hypothesis: The origin of chiral homogeneity and the RNA-world
    József Garay · 2010 · Biosystems
  8. An Aptamer‐Nanotrain Assembled from Six‐Letter DNA Delivers Doxorubicin Selectively to Liver Cancer Cells
    Liqin Zhang, Sai Wang, Zunyi Yang, Shuichi Hoshika, Sitao Xie, Jin Li, Xigao Chen, Shuo Wan, Long Li, Steven A. Benner et al. · 2019 · Angewandte Chemie
  9. Ribozyme-Catalyzed Genetics
    Donald H. Burke · 2004 · Springer eBooks
  10. Evolutionary conservation of putative functional domains in the human homolog of the murine His-1 gene
    Jie Li, Judith C. Rhodes, David S. Askew · 1997 · Gene
  11. A peptidyl transferase ribozyme capable of combinatorial peptide synthesis
    Zhiyong Cui, Lele Sun, Biliang Zhang · 2004 · Bioorganic & Medicinal Chemistry
  12. Cofaktor‐abhängige Selbstspaltung von DNA‐Bibliotheken mit einer 3′‐5′‐Phosphoamidatbindung
    Jens Burmeister, Günter von Kiedrowski, Andrew D. Ellington · 1997 · Angewandte Chemie
  13. Heat‐Flow‐Driven Nonequilibria for Prebiotic Chemistry
    Christof Bernhard Mast · 2024 · ChemSystemsChem
  14. Weak effects of prebiotically plausible peptides on self-triphosphorylation ribozyme function
    Joshua T. Arriola, Shayan Poordian, Estefania Martinez Valdiva, Tommy Le, Luke J. Leman, Joan G. Schellinger, Ulrich F. Müller · 2024 · RSC Chemical Biology
  15. Directionality theory and the origin of life
    Lloyd Demetrius · 2024 · Royal Society Open Science
  16. Prebiotic selection for motifs in a model of template-free elongation of polymers within compartments
    Grant Kinsler, Sam Sinai, Nicholas Keone Lee, Martin A. Nowak · 2017 · PLoS ONE
  17. On the Evolutionary Development of Biological Organization from Complex Prebiotic Chemistry
    Kepa Ruiz‐Mirazo, Álvaro Moreno · 2023 · History, philosophy and theory of the life sciences
  18. A model on the origin of RNA
    Toyoyuki Kitamura, Michel Peyrard, Santiago Cuesta‐López · 2005 · Physical Biology
  19. Functional nucleic acid entrapment in sol–gel derived materials
    Carmen Carrasquilla, John D. Brennan · 2013 · Methods
  20. The EvoGrid: A Framework for Distributed Artificial Chemistry Cameo Simulations Supporting Computational Origins of Life Endeavors
    Bruce Damer, Peter Newman, Richard Gordon, Tom Barbalet, David W. Deamer, Ryan Norkus · 2010 · Artificial Life
  21. Generation of small molecule-binding RNA arrays and their application to fluorogen-binding RNA aptamers
    Charlotte A. Henderson, Callum A. Rail, Louise E. Butt, Helen A. Vincent, Anastasia J. Callaghan · 2019 · Methods
  22. Genome Evolution from Random Ligation of RNAs of Autocatalytic Sets
    Felix Broecker · 2021 · International Journal of Molecular Sciences
  23. What’s So Great about RNA?
    Andrew D. Ellington · 2007 · ACS Chemical Biology
  24. Identification of dynamical hinge points of the L1 ligase molecular switch
    George M. Giambaşu, Tai‐Sung Lee, Carlos P. Sosa, Michael P. Robertson, William G. Scott, Darrin M. York · 2010 · RNA
  25. Reflections of a Darwinian Engineer
    Gerald F. Joyce · 2015 · Journal of Molecular Evolution
  26. Selective Inactivation of Functional RNAs by Ribozyme-Catalyzed Covalent Modification
    Raghav R. Poudyal, Malak Benslimane, Melissa P. Lokugamage, Mackenzie Kate Callaway, Seth Staller, Donald H. Burke · 2016 · ACS Synthetic Biology
  27. Developments in Strain Improvement Technology
    Stephen B. del Cardayré · 2005 · Humana Press eBooks
  28. Toward Evolution in Chemical Reaction Networks
    Sandeep Ameta, Alex W. P. Blokhuis, Cyrille Jeancolas, P. Nghe · 2022 · Royal Society of Chemistry eBooks
  29. Aptamers and Their Potential as Recognition Elements for the Detection of Bacteria
    Casey C. Fowler, Naveen Kumar Navani, Eric D. Brown, Yingfu Li · 2008 · Springer eBooks
  30. Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying
    Noam Prywes, Yale S. Michaels, Ayan Pal, Seung Soo Oh, Jack W. Szostak · 2016 · Chemical Communications
  31. Alignment editing and identification of consensus secondary structures for nucleic acid sequences: interactive use of dot matrix representations
    Jeffrey P. Davis, Nebojša Janjić, David G. Pribnow, Dominic A. Zichi · 1995 · Nucleic Acids Research
  32. RNA Selection and Evolution In Vitro: Powerful Techniques for the Analysis and Identification of new Molecular Tools
    Cristina Romero‐López, R. Díaz-González, Alfredo Berzal‐Herranz · 2007 · Biotechnology & Biotechnological Equipment
  33. Preparation of Second-Generation Phage Libraries
    Nils B. Adey, Willem P.C. Stemmer, Brian K. Kay · 1996 · Elsevier eBooks
  34. Alternative Approaches for the Application of Ribozymes as Gene Therapies for Retroviral Infections
    Thomas Campbell, Bruce A. Sullengert · 1995 · Advances in pharmacology
  35. RNA Replication and the RNA Polymerase Ribozyme
    Falk Wachowius, Philipp Holliger · 2021 · Wiley eBooks
  36. Mapping L1 Ligase Ribozyme Conformational Switch
    George M. Giambaşu, Tai‐Sung Lee, William G. Scott, Darrin M. York · 2012 · Journal of Molecular Biology
  37. Recent Patents of Gene Sequences Relative to DNA Polymerases
    Linda J. Reha-Krantz · 2008 · Recent Patents on DNA & Gene Sequences
  38. DNA shuffling: Modifying the hand that nature dealt
    A. J. Reid · 2000 · In Vitro Cellular & Developmental Biology - Plant
  39. Amplification of an RNA ligase ribozyme under alternating temperature conditions
    Ki-Sun Kim, Sangtaek Oh, Sung Su Yea, Moon‐Young Yoon, Dong‐Eun Kim · 2008 · FEBS Letters
  40. The emergence of molecular machines as a prerequisite of the ancient RNA world evolution
    Alexander S. Spirin · 2013 · Paleontological Journal
  41. Errors and Alternatives in Prebiotic Replication and Catalysis
    Jacques Ninio · 2007 · Chemistry & Biodiversity
  42. Rethinking the tools of the RNA world
    Antony L. Crisp, Thomas Carell · 2018 · eLife
  43. The NTP binding site of the polymerase ribozyme
    Arvin Akoopie, Ulrich F. Müller · 2018 · Nucleic Acids Research
  44. Multi-agent approach to sequence structure simulation in the RNA World hypothesis
    Jaroslaw Synak, Agnieszka Rybarczyk, Jacek Błażewicz · 2020 · PLoS ONE
  45. On the emergence of structural complexity in RNA replicators
    Carlos Oliver, Vladimir Reinharz, Jérôme Waldispühl · 2019 · RNA
  46. The Continuous Evolution In Vitro Technique
    Carolina Díaz Arenas, Niles Lehman · 2010 · Current Protocols in Nucleic Acid Chemistry
  47. Evolution in an RNA World
    Peter M. Schuster · 1998 · Foundations of modern biochemistry
  48. Design, Synthesis, and Amplification of DNA Pools for Construction of Combinatorial Pools and Libraries
    Jack D. Pollard, Sabine D. Bell, Andrew D. Ellington · 2000 · Current Protocols in Molecular Biology
  49. NUCLEIC ACIDS FOR REAGENTLESS BIOSENSORS
    Eun Jeong Cho, Joo-Woon Lee, Manjula Rajendran, Andrew D. Ellington · 2008 · Elsevier eBooks
  50. Phage display
    John F Collins · 1997 · Annual reports in combinatorial chemistry and molecular diversity
  51. Rapid Genetic Selection of Inhibitor-Resistant Protease Mutants: Clinically Relevant and Novel Mutants of the HIV Protease
    Harry J. Sices, Mary Leusink, Alonso Pacheco, Thomas M. Kristie · 2001 · AIDS Research and Human Retroviruses
  52. The Evolution of Cellular Computing
    Laura F. Landweber · 1999 · Biological Bulletin
  53. Ribozymes: Red in tooth and claw
    Michael P. Robertson, Andrew D. Ellington · 1997 · Current Biology
  54. Exploration by lamp light
    Melissa J. Moore · 1995 · Nature
  55. A slippery grip
    Martha J. Fedor · 1994 · Nature Structural & Molecular Biology
  56. Aptamers
    W Lillard James · 2000 · Encyclopedia of Analytical Chemistry
  57. Aptamers
    Subash C. B. Gopinath · 2011 · Encyclopedia of Analytical Chemistry
  58. Landscapes for molecular evolution: Lessons from in vitro selection experiments with nucleic acids
    Sulay D. Jhaveri, Ichiro Hirao, Sabine D. Bell, Kyle W. Uphoff, Andrew D. Ellington · 1997 · Annual reports in combinatorial chemistry and molecular diversity
  59. Opinion: The Key Steps in the Origin of Life to the Formation of the Eukaryotic Cell
    Brunk, Clifford F., Marshall, Charles R. · 2024 · Life
  60. Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs
    Eva S. Hoffmann, Mareike C. De Pascali, Lukas Neu, Christof Domnick, Alice Soldà, Stephanie Kath‐Schorr · 2024 · RSC Chemical Biology
  61. Emergent and Convergent Features in the Laboratory Evolution of Polymerase Ribozymes
    David P. Horning · 2025 · Biochemistry
  62. Geochemical Complexity in Terrestrial Hot Spring Fields: Implications for the Origin of Life
    Martin Julian Van Kranendonk, L. K. Penrose, J. R. Havig, Michael C. Rowe, Kathleen A. Campbell, Eizo Nakamura, Trinity L. Hamilton · 2026 · Astrobiology
  63. Prebiotic world, macroevolution, and Darwin’s theory: a new insight
    Luis Boto, Ignacio Doadrio, Rui Diogo · 2007 · Biology & Philosophy
  64. Aptamer-Based Strategies for Diagnostics
    Paul E. D. Soto Rodriguez, Veronica Irina Calderon Nash · 2019 · Elsevier eBooks
  65. Concurrent Prebiotic Formation of Nucleoside‐Amidophosphates and Nucleoside‐Triphosphates Potentiates Transition from Abiotic to Biotic Polymerization
    Huacan Lin, Eddy Ivanhoe Jiménez, Joshua T. Arriola, Ulrich F. Müller, Ramanarayanan Krishnamurthy · 2021 · Angewandte Chemie
  66. Oligomeric and biogenetic combinatorial libraries
    Gordon Matthew Lowe · 1999 · Natural Product Reports
  67. In vitro evolution and characterization of a ligase ribozyme adapted to acidic conditions: Effect of further rounds of evolution
    Yoshitaka Miyamoto, Naozumi Teramoto, Yukio Imanishi, Yoshihiro Ito · 2005 · Biotechnology and Bioengineering
  68. Identification and characterization of a short 2′–3′ bond-forming ribozyme
    Duncan J. Smith, Maria M. Konarska · 2008 · RNA
  69. In Vitro Selection Using Modified or Unnatural Nucleotides
    Scott M. Knudsen, Michael P. Robertson, Andrew D. Ellington · 2001 · Current Protocols in Nucleic Acid Chemistry
  70. The roots of metabolism
    Cody, George D., Scott, James H. · 2007 · Planets and Life
  71. Retroviral Insertions in the Murine His-1 Locus Activate the Expression of a Novel RNA That Lacks an Extensive Open Reading Frame
    David S. Askew, Jie Li, James N. Ihle · 1994 · Molecular and Cellular Biology
  72. Template‐Directed Ligation: Towards the Synthesis of Sequence Specific Polymers
    Yahaloma Gat, David G. Lynn · 1999 · Wiley eBooks
  73. Climbing Darwin's ladder
    Gerald F. Joyce · 1993 · Current Biology
  74. Base‐pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA‐coat protein complex
    Michael Boyce, Felicia Houser‐Scott, Laura M. Guogas, Lee Gehrke · 2005 · Journal of Molecular Recognition
  75. Design of Polypeptides
    Bernd Gutte, Stephan Klauser · 1995 · Elsevier eBooks
  76. Chemistry of Antisense Oligonucleotides
    Christian R. Noe, Lucius Kaufhold · 2000 · Methods and principles in medicinal chemistry
  77. Ribozyme Selection
    Andrew D. Ellington, Michael P. Robertson · 1999 · Elsevier eBooks
  78. Designing a Bio-responsive Robot from DNA Origami
    Eldad Ben Ishay, Almogit Abu-Horowitz, Ido Bachelet · 2013 · Journal of Visualized Experiments
  79. RNA structure: implications in viral infections and neurodegenerative diseases
    Suiru Lu, Yongkang Tang, Shaozhen Yin, Lei Sun · 2024 · Advanced Biotechnology
  80. The non-canonical nucleotides and prebiotic evolution
    Alexey S. Ruzov, Alexander S. Ermakov · 2025 · Biosystems
  81. A Case Study of the Dynamics of In Vitro DNA Evolution Under Constant Selection Pressure
    Xiaojing Yang, Xili Liu, Chunbo Lou, Jianguo Chen, Qi Ouyang · 2008 · Journal of Molecular Evolution
  82. Präbiotisch plausible RNA‐Aktivierung kompatibel mit ribozymkatalysierter Ligation
    Emilie Yeonwha Song, Eddy Ivanhoe Jiménez, Huacan Lin, Kristian Kyle Le Vay, Ramanarayanan Krishnamurthy, Hannes Mutschler · 2020 · Angewandte Chemie
  83. The evolution of DNA computing: nature's solution to a path problem
    Laura F. Landweber · 2002 · IEEE International Joint Symposia on Intelligence and Systems (IJSIS)
  84. Man versus Machine versus Ribozyme
    Andrew D. Ellington · 2008 · PLoS Biology
  85. Expanded divalent metal-ion tolerance of evolved ligase ribozymes
    Craig A. Riley, Niles Lehman · 2003 · Biochimie
  86. Genetic Exchange Leading to Self-Assembling RNA Species upon Encapsulation in Artificial Protocells
    Sergio-Francis M. Zenisek, Eric J. Hayden, Niles Lehman · 2007 · Artificial Life
  87. Monitoring protein modification with allosteric ribozymes
    Narendra K. Vaish, Karl Kossen, Lori E. Andrews, Christopher Pasko, Scott D. Seiwert · 2004 · Methods
  88. Protein Engineering
    Thomas Willemsen, Urs B. Hagemann, Eva M. Jouaux, Sabine C. Stebel, Jody M. Mason, Kristian Mark Müller, Katja M. Arndt · 2008 · Springer protocols handbooks/Springer protocols
  89. The Prebiotic Synthesis and Replication of RNA Oligomers: The Transition from Prebiotic Molecules to the RNA World
    James P. Ferris · 1994 · Springer eBooks
  90. RNA Pathfinder – Global Properties of Neutral Networks
    Ulrike Göbel, Christian V. Forst · 2002 · Zeitschrift für Physikalische Chemie
  91. Spontaneous Cooperative Assembly of Replicative Catalytic RNA Systems
    Nilesh Vaidya · 2000
  92. Catalysis of Organic Reactions by RNA—Strategies for the Selection of Catalytic RNAs
    Andres Jäschke · 1998 · Elsevier eBooks
  93. A History of Genomic Structures: The Big Picture
    Nicolas Carels · 2015 · Springer eBooks
  94. Designer red cells
    Robert B. Wilson, Steven L. Spitalnik · 1994 · Transfusion
  95. Evolving Wonder-RNAs in a Test Tube
    Yingfu Li · 2013 · Journal of Molecular Evolution
  96. Two RNA Worlds: Toward the Origin of Replication, Genes, Recombination, and Repair
    Dirk‐Henner Lankenau · 2011 · Springer eBooks
  97. Water/Oil Emulsions with Controlled Droplet Sizes for In Vitro Selection Experiments
    Douglas Magde, Arvin Akoopie, Michael D. Magde, Ulrich F. Müller · 2021 · ACS Omega
  98. RNA life on the edge of catastrophe
    Irene A. Chen · 2024 · Proceedings of the National Academy of Sciences
  99. Introductory Chapter: Artificial Enzyme Produced by Directed Evolution Technology
    Naofumi Shiomi · 2019 · IntechOpen eBooks
  100. Verification of chemical evolution of RNA under hydrothermal environments on the primitive Earth
    Kunio Kawamura, Laura Da Silva, Mari Ogawa, Noriko Konagaya, Marie‐Christine Maurel · 2015 · BIO Web of Conferences