Isolation of New Ribozymes from a Large Pool of Random Sequences

Bartel, David P., Szostak, Jack W.·1993·Science

Cited by (901)

Items 201–300 of 901

  1. Exploring molecular diversity with combinatorial shape libraries
    Daniel J. Kenan, Donald E. Tsai, J. D. Keene · 1994 · Trends in Biochemical Sciences
  2. The Nature of Life: Classical and Contemporary Perspectives from Philosophy and Science
    Mark A. Bedau, Carol E. Cleland · 2010
  3. Origins of Life: The Primal Self-Organisation
    H. Egel, D. Lankenau, A. Mulkidjanian · 2011 · Springer eBooks
  4. Searching sequence space for protein catalysts
    Sean V. Taylor, Kai U. Walter, Peter Kast, Donald Hilvert · 2001 · Proceedings of the National Academy of Sciences
  5. Searching Sequence Space
    Willem P.C. Stemmer · 1995 · Nature Biotechnology
  6. Order, dynamics and metal-binding in the lead-dependent ribozyme 1 1Edited by I. Tinoco
    Pascale Legault, Charles G. Hoogstraten, Elana Metlitzky, Arthur Pardi · 1998 · Journal of Molecular Biology
  7. An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination
    Yueyao Wang, Yao Wang, Dongfan Song, Xin Sun, Zhe Li, Jiayu Chen, Hanyang Yu · 2021 · Nature Chemistry
  8. A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA
    Niklas Freund, Alexander I. Taylor, Sebastian Arangundy‐Franklin, Nithya Subramanian, Sew‐Yeu Peak‐Chew, Amy M. Whitaker, Bret Freudenthal, Mikhail Abramov, Piet A. Herdewijn, Philipp Holliger · 2022 · Nature Chemistry
  9. Nucleic acids: function and potential for abiogenesis
    Falk Wachowius, James Attwater, Philipp Holliger · 2017 · Quarterly Reviews of Biophysics
  10. Phosphorylation of Adenosine with Trimetaphosphate Under Simulated Prebiotic Conditions
    Changmei Cheng, Chang Fan, Rong Wan, Chun-yuan Tong, Zhiwei Miao, Jing Chen, Yufen Zhao · 2002 · Origins of Life and Evolution of Biospheres
  11. Reading, Writing, and Modulating Genetic Information with Boranophosphate Mimics of Nucleotides, DNA, and RNA
    Barbara Ramsay Shaw, Mikhail I. Dobrikov, Xin Wang, Jing Wan, Kaizhang He, Jinlai Lin, PING LI, Vladimir K. Rait, Zinaida A. Sergueeva, Dmitri S. Sergueev · 2003 · Annals of the New York Academy of Sciences
  12. Nucleic acid enzymes: Playing with a fuller deck
    Gerald F. Joyce · 1998 · Proceedings of the National Academy of Sciences
  13. Biomineralization. From Biology to Biotechnology and Medical Application. Herausgegeben von Edmund Baeuerlein
    Matthias Epple · 2001 · Angewandte Chemie
  14. Abundance of correctly folded RNA motifs in sequence space, calculated on computational grids
    Knight, R. · 2005 · Nucleic Acids Research
  15. Processive RNA polymerization and promoter recognition in an RNA World
    Razvan Cojocaru, Peter J. Unrau · 2021 · Science
  16. DNA and RNA induced enantioselectivity in chemical synthesis
    Gérard Roelfes · 2006 · Molecular BioSystems
  17. A Comparison of Directed Evolution Approaches Using the β-Glucuronidase Model System
    Lori A. Rowe, Melissa L. Geddie, Omar B. Alexander, Ichiro Matsumura · 2003 · Journal of Molecular Biology
  18. Structural and Kinetic Characterization of an Acyl Transferase Ribozyme
    Hiroaki Suga, Peter A. Lohse, Jack W. Szostak · 1998 · Journal of the American Chemical Society
  19. The Structural Role of Mg2+ Ions in a Class I RNA Polymerase Ribozyme: A Molecular Simulation Study
    Jacopo Sgrignani, Alessandra Magistrato · 2012 · The Journal of Physical Chemistry B
  20. The Origin of Life – How Long did it Take?
    Leslie E. Orgel · 1998 · Origins of Life and Evolution of Biospheres
  21. Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition.
    Yaw-Ling Lin, A Padmapriya, Kathleen M. Morden, Subashinie Jayasena · 1995 · Proceedings of the National Academy of Sciences
  22. Pyranosyl‐RNA: Further Observations on Replication
    Martin H. Bolli, Ronald Micura, Stefan Pitsch, Albert Eschenmoser · 1997 · Helvetica Chimica Acta
  23. Isolation of a ribozyme with 5′-5′ ligase activity
    Karen B. Chapman, Jack W. Szostak · 1995 · Chemistry & Biology
  24. Direct selection of trans -acting ligase ribozymes by in vitro compartmentalization
    Matthew Levy, Karl E. Griswold, Andrew D. Ellington · 2005 · RNA
  25. Continuous In Vitro Evolution of a Ribozyme that Catalyzes Three Successive Nucleotidyl Addition Reactions
    Kathleen E. McGinness, Martin C. Wright, Gerald F. Joyce · 2002 · Chemistry & Biology
  26. Landscapes and molecular evolution
    Peter M. Schuster · 1997 · Physica D Nonlinear Phenomena
  27. Bio‐affinity characterization mass spectrometry
    James E. Bruce, Gordon Anderson, Ruidan Chen, Xueheng Cheng, David C. Gale, Steven A. Hofstadler, Brenda L. Schwartz, Richard D. Smith · 1995 · Rapid Communications in Mass Spectrometry
  28. Strategies for Covalent Labeling of Long RNAs
    Hannah Depmeier, Eva Hoffmann, Lisa Bornewasser, Stephanie Kath‐Schorr · 2021 · ChemBioChem
  29. Parallel molecular computation
    John H. Reif · 1995 · ACM Symposium on Parallelism in Algorithms and Architectures (SPAA)
  30. Design, Synthesis, and Amplification of DNA Pools for In Vitro Selection
    Bradley Hall, J. Morgan Micheletti, Pooja Satya, Krystal Ogle, Jack D. Pollard, Andrew D. Ellington · 2009 · Current Protocols in Molecular Biology
  31. Synthetic biology with RNA motifs
    Hirohide Saito, Tan Inoue · 2008 · The International Journal of Biochemistry & Cell Biology
  32. An optimized kit-free method for making strand-specific deep sequencing libraries from RNA fragments
    Erin E. Heyer, Hakan Özadam, Emiliano P. Ricci, Can Cenik, Melissa J. Moore · 2014 · Nucleic Acids Research
  33. Progress in synthesizing protocells
    Ö. Duhan Toparlak, Sheref S. Mansy · 2018 · Experimental Biology and Medicine
  34. Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library
    Thomas Tuschl, Phillip A. Sharp, David P. Bartel · 1998 · The EMBO Journal
  35. Evolutionary Optimization of the Catalytic Properties of a DNA-Cleaving Ribozyme
    Joyce Tsang, Gerald F. Joyce · 1994 · Biochemistry
  36. Are the different hypotheses on the emergence of life as different as they seem?
    Fry, Iris · 1995 · Biology & Philosophy
  37. Ligand‐dependent ribozymes
    Michele Felletti, Jörg S. Hartig · 2016 · Wiley Interdisciplinary Reviews - RNA
  38. Aptamers for SARS‐CoV‐2: Isolation, Characterization, and Diagnostic and Therapeutic Developments
    Ryan Amini, Zijie Zhang, Jiuxing Li, Jimmy Gu, John D. Brennan, Yingfu Li · 2022 · Analysis & Sensing
  39. RNA aptamers directed to discrete functional sites on a single protein structural domain
    Hua Shi, Xiaochun Fan, Aarti Sevilimedu, John T. Lis · 2007 · Proceedings of the National Academy of Sciences
  40. Monitoring post-translational modification of proteins with allosteric ribozymes
    Narendra K. Vaish, Fang Dong, Lori E. Andrews, Rebecca E. Schweppe, Natalie G. Ahn, Lawrence Mitchell Blatt, Scott D. Seiwert · 2002 · Nature Biotechnology
  41. Closing the circle: replicating RNA with RNA.
    Cheng, L. K. L., Unrau, P. J. · 2010 · Cold Spring Harbor Perspectives in Biology
  42. A reverse transcriptase ribozyme
    Samanta, Biswajit, Joyce, Gerald F · 2017 · eLife
  43. Tracing Sequence Diversity Change of RNA-Cleaving Deoxyribozymes under Increasing Selection Pressure during in Vitro Selection
    Kenny Schlosser, Yingfu Li · 2004 · Biochemistry
  44. RNA structural patterns and splicing: molecular basis for an RNA-based enhancer.
    Domenico Libri, Françoise Stutz, Terri McCarthy, Michael Rosbash · 1995 · Europe PMC (PubMed Central)
  45. The new world of ribozymes
    Luc Jaeger · 1997 · Current Opinion in Structural Biology
  46. The RNA World on Ice: A New Scenario for the Emergence of RNA Information
    Alexander V. Vlassov, Sergei A. Kazakov, Brian H. Johnston, Laura F. Landweber · 2005 · Journal of Molecular Evolution
  47. Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
    Hannes Mutschler, Alexander I Taylor, Benjamin T. Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet A. Herdewijn, Philipp Holliger · 2018 · eLife
  48. NMR spectroscopy of ribonucleic acids
    Jeremy Flinders, Thorsten Dieckmann · 2006 · Progress in Nuclear Magnetic Resonance Spectroscopy
  49. Mechanistic Studies of (Porphinato)Iron-Catalyzed Isobutane Oxidation. Comparative Studies of Three Classes of Electron-Deficient Porphyrin Catalysts
    Kevin T. Moore, István T. Horváth, Michael J. Therien · 2000 · Inorganic Chemistry
  50. Non-unity molecular heritability demonstrated by continuous evolution in vitro
    Thomas Schmitt, Niles Lehman · 1999 · Chemistry & Biology
  51. Libraries of non-covalent hydrogen-bonded assemblies; combinatorial synthesis of supramolecular systems
    Mercedes Crego Calama, Peter Timmerman, David N. Reinhoudt, Mercedes Crego Calama, Ron Hulst, Peter Timmerman, Roel H. Fokkens, Nico M. M. Nibbering · 1998 · Chemical Communications
  52. Hammerhead ribozyme engineering
    Nassim Usman · 1996 · Current Opinion in Structural Biology
  53. Primordial Genetics: Phenotype of the Ribocyte
    Michael Yarus · 2002 · Annual Review of Genetics
  54. Artificial Functional Nucleic Acids: Aptamers, Ribozymes, and Deoxyribozymes Identified by In Vitro Selection
    Scott K. Silverman · 2009 · Springer eBooks
  55. Single Nucleotide‐Catalyzed Biomimetic Reductive Amination
    Atul Kumar, Siddharth Sharma, Ram Awatar Maurya · 2010 · Advanced Synthesis & Catalysis
  56. The in vitro selection world
    Kenan Jijakli, Basel Khraiwesh, Weiqi Fu, Liming Luo, Amnah Salem Alzahmi, Joseph Koussa, Amphun Chaiboonchoe, Serdal Kırmızıaltın, Laising Yen, Kourosh Salehi‐Ashtiani · 2016 · Methods
  57. Emergence of a dual-catalytic RNA with metal-specific cleavage and ligase activities: The spandrels of RNA evolution
    Laura F. Landweber, Irina D. Pokrovskaya · 1999 · Proceedings of the National Academy of Sciences
  58. Synthesis and Characterization of an RNA Dinucleotide Containing a 3‘-S-Phosphorothiolate Linkage
    Lara B. Weinstein, David J. Earnshaw, Richard Cosstick, Thomas R. Cech · 1996 · Journal of the American Chemical Society
  59. RNA-Catalyzed RNA Ligation on an External RNA Template
    Kathleen E. McGinness, Gerald F. Joyce · 2002 · Chemistry & Biology
  60. Self-Incorporation of coenzymes by ribozymes
    Ronald R. Breaker, Gerald F. Joyce · 1995 · Journal of Molecular Evolution
  61. Improved production and function of llama heavy chain antibody fragments by molecular evolution
    Richard H.J van der Linden, Bernard de Geus, Leon G. J. Frenken, Hans Peters, C. Theo Verrips · 2000 · Journal of Biotechnology
  62. Encoding folding paths of RNA switches
    A. Xayaphoummine, Virgile Viasnoff, Sébastien Harlepp, Hervé Isambert · 2006 · Nucleic Acids Research
  63. Structured sequences emerge from random pool when replicated by templated ligation
    Patrick W. Kudella, Alexei V. Tkachenko, Annalena Salditt, Sergei Maslov, Dieter Braun · 2021 · Proceedings of the National Academy of Sciences
  64. Genotypes with phenotypes: Adventures in an RNA toy world
    Peter Schuster · 1997 · Biophysical Chemistry
  65. Emergence of a fast-reacting ribozyme that is capable of undergoing continuous evolution
    Sarah B. Voytek, Gerald F. Joyce · 2007 · Proceedings of the National Academy of Sciences
  66. Synthesis, incorporation efficiency, and stability of disulfide bridged functional groups at RNA 5′-ends
    Gerhard Sengle, Andreas Jenne, Paramjit S. Arora, Burckhard Seelig, James S. Nowick, Andres Jäschke, Michael Famulok · 2000 · Bioorganic & Medicinal Chemistry
  67. Improved polymerase ribozyme efficiency on hydrophobic assemblies
    Müller, Ulrich F., Bartel, David P. · 2008 · RNA
  68. The structural basis of RNA-catalyzed RNA polymerization
    Shechner, David M, Bartel, David P · 2011 · Nature Structural & Molecular Biology
  69. A ribozyme that triphosphorylates RNA 5′-hydroxyl groups
    Janina E. Moretti, Ulrich F. Müller · 2014 · Nucleic Acids Research
  70. A view into the origin of life: aminoacyl-tRNA synthetases
    Lluı́s Ribas de Pouplana, PAUL R. SCHIMMEL · 2000 · Cellular and Molecular Life Sciences
  71. Combining SELEX Screening and Rational Design to Develop Light-Up Fluorophore−RNA Aptamer Pairs for RNA Tagging
    Jungjoon Lee, Kyung Hyun Lee, Jongho Jeon, Anca Dragulescu‐Andrasi, Fei Xiao, Jianghong Rao · 2010 · ACS Chemical Biology
  72. On the structural repertoire of pools of short, random RNA sequences
    Michael Stich, Carlos Briones, Susanna C. Manrubia · 2008 · Journal of Theoretical Biology
  73. Chemical synthesis of lipids and the origin of life
    James A. Oro · 1995 · Journal of Biological Physics
  74. Predicting Secondary Structural Folding Kinetics for Nucleic Acids
    Peinan Zhao, Wenbing Zhang, Shi‐Jie Chen · 2010 · Biophysical Journal
  75. Vierzig Jahre Evolution im Reagenzglas
    Gerald F. Joyce · 2007 · Angewandte Chemie
  76. Selection of Aptamers Against Whole Living Cells: From Cell-SELEX to Identification of Biomarkers
    Nam Nguyen Quang, Anna Miodek, Agnès Cibiel, Frederic Ducongè · 2017 · Methods in molecular biology
  77. A Threose Nucleic Acid Enzyme with RNA Ligase Activity
    Yao Wang, Yueyao Wang, Dongfan Song, Xin Sun, Ze Zhang, Xintong Li, Zhe Li, Hanyang Yu · 2021 · Journal of the American Chemical Society
  78. Were the first organisms heat engines? A new model for biogenesis and the early evolution of biological energy conversion
    Anthonie W. J. Muller · 1995 · Progress in Biophysics and Molecular Biology
  79. Re-creating the RNA world
    Ichiro Hirao, Andrew D. Ellington · 1995 · Current Biology
  80. Enrichment for RNA molecules that bind a Diels-Alder transition state analog.
    K N Morris, Theodore M. Tarasow, Carol M. Julin, S L Simons, Donald Hilvert, Larry Gold · 1994 · Proceedings of the National Academy of Sciences
  81. Cofactor‐Assisted Self‐Cleavage in DNA Libraries with a 3′–5′‐Phosphoramidate Bond
    Jens Burmeister, Günter von Kiedrowski, Andrew D. Ellington · 1997 · Angewandte Chemie International Edition in English
  82. RNA Synthesis by in Vitro Selected Ribozymes for Recreating an RNA World
    Lyssa L. Martin, Peter J. Unrau, Ulrich Müller · 2015 · Life
  83. A ribozyme that ligates RNA to protein
    Scott Baskerville, David P. Bartel · 2002 · Proceedings of the National Academy of Sciences
  84. Promiscuous Ribozymes and Their Proposed Role in Prebiotic Evolution
    Evan Janzen, Celia Blanco, Huan Peng, Josh Kenchel, Irene A. Chen · 2020 · Chemical Reviews
  85. RNA modularity for synthetic biology
    Wade W. Grabow, Luc Jaeger · 2013 · F1000Prime Reports
  86. The Fidelity of Template-Directed Oligonucleotide Ligation and the Inevitability of Polymerase Function
    Kenneth D. James, Andrew D. Ellington · 1999 · Origins of Life and Evolution of Biospheres
  87. 23S rRNA Similarity from Selection for Peptidyl Transferase Mimicry
    Mark Welch, Irene H. Majerfeld, Michael Yarus · 1997 · Biochemistry
  88. Creation of libraries with long ORFs by polymerization of a microgene
    Kiyotaka Shiba, Yuki Takahashi, Tetsuo Noda · 1997 · Proceedings of the National Academy of Sciences
  89. Discovering covalent inhibitors of protein–protein interactions from trillions of sulfur(VI) fluoride exchange-modified oligonucleotides
    Zichen Qin, Kaining Zhang, Ping He, Xue Zhang, Miao Xie, Yucheng Fu, Chunmei Gu, Yiying Zhu, Aijun Tong, Hongping Wei et al. · 2023 · Nature Chemistry
  90. Ratcheting synthesis
    Stefan Borsley, James Gallagher, David A. Leigh, Benjamin M. W. Roberts · 2023 · Nature Reviews Chemistry
  91. Production of pure and functional RNA for in vitro reconstitution experiments
    Franziska Theresia Edelmann, Annika Niedner, Dierk Niessing · 2013 · Methods
  92. Homochirality and chemical evolution: new vistas and reflections on recent models
    Martı́n Ávalos, Reyes Babiano, Pedro Cintas, José L. Jiménez, Juan C. Palacios · 2010 · Tetrahedron Asymmetry
  93. Conversion of a Ribozyme to a Deoxyribozyme through In Vitro Evolution
    Natasha Paul, Greg Springsteen, Gerald F. Joyce · 2006 · Chemistry & Biology
  94. Biotechnology match making: screening orphan ligands and receptors
    C Williams · 2000 · Current Opinion in Biotechnology
  95. Constructing an RNA world
    David P. Bartel, Peter J. Unrau · 1999 · Trends in Biochemical Sciences
  96. Introduction to the Synthesis and Purification of Oligonucleotides
    Andrew D. Ellington, Jack D. Pollard · 2000 · Current Protocols in Nucleic Acid Chemistry
  97. Next-generation sequencing reveals how RNA catalysts evolve from random space
    Sandeep Ameta, Marie‐Luise Winz, Christopher Previti, Andres Jäschke · 2013 · Nucleic Acids Research
  98. Improving the odds: Influence of starting pools on in vitro selection outcomes
    Kelsey Pobanz, Andrej Lupták · 2016 · Methods
  99. RNA-directed construction of structurally complex and active ligase ribozymes through recombination
    Eric J. Hayden, Craig A. Riley, Aaron S. Burton, Niles Lehman · 2005 · RNA
  100. Competitive Reaction of Axial Ligands during Biomimetic Oxygenations
    James P. Collman, Allis Chien, Todd A. Eberspacher, Min Zhong, John I. Brauman · 2000 · Inorganic Chemistry