Isolation of New Ribozymes from a Large Pool of Random Sequences
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- Directed Evolution: A Historical Exploration into an Evolutionary Experimental System of Nanobiotechnology, 1965–2006Eun Sung Kim · 2008 · Minerva
- Early Replicons: Origin and Evolution**Dedicated to Manfred Eigen, the pioneer of molecular evolution and intellectual father of quasispecies theory, on the occasion of his 80th birthday.Peter M. Schuster, Peter Florian Stadler · 2008 · Elsevier eBooks
- Peptide synthesis through evolutionKoji Tamura, Rebecca W. Alexander · 2004 · Cellular and Molecular Life Sciences
- In Vitro Selection of a Deoxyribozyme That Can Utilize Multiple SubstratesMatthew Levy, Andrew D. Ellington · 2002 · Journal of Molecular Evolution
- Synthesis and characterization of topologically linked single-stranded DNA ringsLieven P. Billen, Yingfu Li · 2004 · Bioorganic Chemistry
- In Vitro Selection Procedures for Identifying DNA and RNA Aptamers Targeted to Nucleic Acids and ProteinsEric Dausse, Christian Cazenave, Bernard Rayner, Jean‐Jacques Toulmé · 2004 · Humana Press eBooks
- Molecular evolution: A theory approaches experimentsChristian V. Forst · 1998 · Journal of Biotechnology
- In Vitro Selection of RNA Aptamers Binding to Nanosized DNA for Constructing Artificial RiboswitchesAtsushi Ogawa, Yu Itoh · 2020 · ACS Synthetic Biology
- Concurrent Prebiotic Formation of Nucleoside‐Amidophosphates and Nucleoside‐Triphosphates Potentiates Transition from Abiotic to Biotic PolymerizationHuacan Lin, Eddy Ivanhoe Jiménez, Joshua T. Arriola, Ulrich F. Müller, Ramanarayanan Krishnamurthy · 2021 · Angewandte Chemie International Edition
- Les aptamères ou l'évolution moléculaire dirigée : sélection et applicationsFabien Chauveau, Carine Pestourie, Bertrand Tavitian · 2006 · Pathologie Biologie
- Characterization of Highly Efficient RNA‐Cleaving DNAzymes that Function at Acidic pH with No Divalent Metal‐Ion CofactorsAleksandra Kasprowicz, Kamila Stokowa‐Sołtys, Małgorzata Jeżowska‐Bojczuk, Jan Wrzesiński, Jerzy Ciesiołka · 2016 · ChemistryOpen
- Screening of conformationally constrained random polypeptide libraries displayed on a protein scaffoldNobuhide Doi, Hiroshi Yanagawa · 1998 · Cellular and Molecular Life Sciences
- Tailoring RNA modular units on a common scaffold: A modular ribozyme with a catalytic unit for β-nicotinamide mononucleotide-activated RNA ligationYuki Fujita, Hiroyuki Furuta, Yoshiya Ikawa · 2009 · RNA
- Promiscuous Catalysis by the Tetrahymena Group I RibozymeMarcello Forconi, Daniel Herschlag · 2005 · Journal of the American Chemical Society
- Catalysis: design versus selectionSteven A. Benner · 1993 · Science
- A primer on model-guided exploration of fitness landscapes for biological sequence designSam Sinai, Eric D. Kelsic · 2020 · arXiv (Cornell University)
- A new 2′-hydroxyl protecting group for the automated synthesis of oligoribonucleotidesHimanshu Rastogi, David A. Usher · 1995 · Nucleic Acids Research
- Design of highly active double-pseudoknotted ribozymes: a combined computational and experimental studyRyota Yamagami, Mohammad Kayedkhordeh, David H. Mathews, Philip C. Bevilacqua · 2018 · Nucleic Acids Research
- An artificial life model for predicting the tertiary structure of unknown proteins that emulates the folding processRaffaele Calabretta, Stefano Nolfi, Domenico Parisi · 1995 · Lecture notes in computer science
- Fitness Landscapes of Functional RNAsÁdám Kun, Eörs Szathmáry · 2015 · Life
- Diverse Mechanisms of RNA RecombinationAnatoly P. Gmyl, Vadim I. Agol · 2005 · Molecular Biology
- [49] Ribozymes in treatment of inherited retinal diseaseLynn C. Shaw, Patrick O. Whalen, Kimberly A. Drenser, Weiming Yan, William W. Hauswirth, Alfred S. Lewin · 2000 · Methods in enzymology on CD-ROM/Methods in enzymology
- Nucleic acid based sensorsFrank F. Bier, J. P. Früste · 1997 · Experientia supplementum
- Chapter 30. Catalytic RNA (Ribozymes) as DrugsNassim Usman, James A. McSwiggen · 1995 · Annual reports in medicinal chemistry
- Identification of Aptamers Against the DNA Template for In Vitro Transcription of the HIV-1 TAR ElementClaudine Boiziau, Eric Dausse, RAKESH MISHRA, Frederic Ducongè, Jean‐Jacques Toulmé · 1997 · Antisense and Nucleic Acid Drug Development
- Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activationSaurja DasGupta, Zoe Weiss, Collin R. Nisler, Jack W. Szostak · 2024 · Proceedings of the National Academy of Sciences
- In Vivo Production of RNA Aptamers and Nanoparticles: Problems and ProspectsOusama Al Shanaa, Andrey Mikhaylovich Rumyantsev, Elena Viktorovna Sambuk, Marina Vladimirovna Padkina · 2021 · Molecules
- A scalable framework for the discovery of functional helicase substrates and helicase-driven regulatory switchesMildred Delaleau, Eric Eveno, Isabelle Simon, Annie Schwartz, Marc Boudvillain · 2022 · Proceedings of the National Academy of Sciences
- RNA-Binding Proteins as Epigenetic Regulators of Brain Functions and Their Involvement in NeurodegenerationCarlo Maria Di Liegro, Gabriella Schiera, Giuseppe Schirò, Italia Di Liegro · 2022 · International Journal of Molecular Sciences
- Complexity through Recombination: From Chemistry to BiologyNiles Lehman, Carolina Díaz Arenas, Wesley A. White, Francis J. Schmidt · 2010 · Entropy
- Molecular computing: Does DNA compute?Daniel E. Rozen, Steve McGrew, Andrew D. Ellington · 1996 · Current Biology
- Universal labeling of 5′-triphosphate RNAs by artificial RNA ligase enzyme with broad substrate specificityJohn Haugner, Burckhard Seelig · 2013 · Chemical Communications
- Why exobiology on Mars?André Brack · 1996 · Planetary and Space Science
- Combinatorial library diversity: probability assessment of library populationsB Ward · 1998 · Nucleic Acids Research
- Fishing for fresh catalystsThomas R. Cech · 1993 · Nature
- Drift and Conservatism in RNA Virus EvolutionMonica Sola, Simon Wain–Hobson · 1999 · Elsevier eBooks
- Ribozymes in WonderlandAndrew D. Ellington, Michael P. Robertson, Jim Bull · 1997 · Science
- Originator dynamicsManapat, Michael, Ohtsuki, Hisashi, Bürger, Reinhard, Nowak, Martin A. · 2009 · Journal of Theoretical Biology
- Single‐Atom Enzymes: From Evolutionary Insights, Precision Engineering to Breakthroughs in Biomedical ApplicationsYe Xu, Chuhuang Dong, Xueliang Liu, Dali Wei, Zhejie Chen, Huayuan Zhou, Jiabei Li, Yu Pu Yang, Weihong Tan · 2025 · Small
- Using predictive Bayesian Monte Carlo- Markov Chain methods to provide a probablistic solution for the Drake equationFrederick Bloetscher · 2018 · Acta Astronautica
- Investigation ofde novo Totally Random Biosequences, Part IIIDavide De Lucrezia, Marco Franchi, Cristiano Chiarabelli, Enzo Gallori, Pier Luigi Luisi · 2006 · Chemistry & Biodiversity
- Evolution and synthetic biologyMarya Y. Ornelas, Jason E. Cournoyer, Stanley Bram, Angad P. Mehta · 2023 · Current Opinion in Microbiology
- Simulating the origins of life: The dual role of RNA replicases as an obstacle to evolutionSzostak, Natalia, Synak, Jaroslaw, Borowski, Marcin, Wasik, Szymon, Blazewicz, Jacek · 2017 · PLOS ONE
- Generation and Development of RNA Ligase Ribozymes with Modular Architecture Through “Design and Selection”Yuki Fujita, Junya Ishikawa, Hiroyuki Furuta, Yoshiya Ikawa · 2010 · Molecules
- Structural Trends in First-Row Transition-Metal Bis(benzimidazole) ComplexesPramatha Payra, Huichang Zhang, Wai-Him Kwok, Maosheng Duan, Judith C. Gallucci, Michael K. Chan · 2000 · Inorganic Chemistry
- Nucleotides that are essential but not conserved; a sufficient L-tryptophan site in RNAIrene H. Majerfeld, Jana Vacek Chocholoušová, Vikas Malaiya, Jeremy Joseph Widmann, Daniel T. McDonald, Jens Reeder, Matthew K. Iyer, Mali Illangasekare, Michael Yarus, Rob D. Knight · 2010 · RNA
- A Method to Select Chemically Modified Aptamers DirectlyClaudine Boiziau, Jean‐Jacques Toulmé · 2001 · Antisense and Nucleic Acid Drug Development
- Investigation ofde novo Totally Random Biosequences, Part IVDavide De Lucrezia, Marco Franchi, Cristiano Chiarabelli, Enzo Gallori, Pier Luigi Luisi · 2006 · Chemistry & Biodiversity
- Limits to Our Knowledge of EvolutionMichael Ruse · 2000 · Springer eBooks
- The Scope of SelectionMichael Yarns, Rob D. Knight · 2007 · Springer eBooks
- A four-track perspective for bottom-up synthetic cellsPasquale Stano · 2022 · Frontiers in Bioengineering and Biotechnology
- Pioneering role of RNA in the early evolution of lifeIsrael Muñoz‐Velasco, Adrián Cruz-González, Ricardo Hernández-Morales, José Alberto Campillo-Balderas, Wolfgang Cottom-Salas, Rodrigo Jácome, Alberto Vázquez-Salazar · 2024 · Genetics and Molecular Biology
- Exploring the space of self-reproducing ribozymes using generative modelsCamille N. Lambert, Vaitea Opuu, Francesco Calvanese, Polina Pavlinova, Francesco Zamponi, Eric J. Hayden, Martin Weigt, Matteo Smerlak, Philippe Nghe · 2025 · Nature Communications
- Pairing statistics and melting of random DNA oligomers: Finding your partner in superdiverse environmentsSimone Di Leo, Stefano Marni, Carlos A. Plata, Tommaso P. Fraccia, Gregory P. Smith, Amos Maritan, Samir Simon Suweis, Tommaso Bellini · 2022 · PLoS Computational Biology
- Non-enzymatic recombination of RNA: Ligation in loopsYaroslav Staroseletz, Sergey Nechaev, Elena V. Bichenkova, Richard A. Bryce, Catherine Watson, Valentin V. Vlassov, Зенкова Марина Аркадьевна · 2017 · Biochimica et Biophysica Acta (BBA) - General Subjects
- DNAzymes at Work: A DFT Computational Investigation on the Mechanism of 9DB1Edoardo Jun Mattioli, Andréa Bottoni, Matteo Calvaresi · 2019 · Journal of Chemical Information and Modeling
- Synthesis and Characterization of the Dimethyl-Substituted Bisbenzimidazole Ligand and Its Manganese ComplexWai-Him Kwok, Huichang Zhang, Pramatha Payra, Maosheng Duan, Shao‐Ching Hung, Dean H. Johnston, Judith C. Gallucci, Ewa Skrzypczak‐Jankun, Michael K. Chan · 2000 · Inorganic Chemistry
- The Combinatorial Library: A Multifunctional ResourceJane S. Schultz, Jerome S. Schultz · 1996 · Biotechnology Progress
- New Concepts: Manipulation of the Wound-Healing ResponseMaria Francesca Cordeiro, Nick L. Occleston, Peng Tee Khaw · 1997 · KARGER eBooks
- In vitro evolution of coenzyme-independent variants from the glmS ribozyme structural scaffoldMatthew W. L. Lau, Adrian R. Ferré-D’Amaré · 2016 · Methods
- Constructing an RNA worldDavid P. Bartel, Peter J. Unrau · 1999 · Trends in Genetics
- Effect of Microwave Radiation on Copper(II) 2,2‘-Bipyridyl-Mediated Hydrolysis of Bis(p-nitrophenyl) Phosphodiester and Enzymatic Hydrolysis of CarbohydratesKonrad G. Kabza, Jason E. Gestwicki, Jessica L. McGrath, H. Michael Petrassi · 1996 · The Journal of Organic Chemistry
- In vitro adaptation of a ligase ribozyme for activity under a low‐pH conditionYoshitaka Miyamoto, Naozumi Teramoto, Yukio Imanishi, Yoshihiro Ito · 2001 · Biotechnology and Bioengineering
- The Role of Neutral Mutations in the Evolution of RNA MoleculesPeter M. Schuster · 1997 · Springer eBooks
- High throughput screening by multichannel glass fiber fluorimetryAndreas Schober, Rolf Günther, Uwe Tangen, Gaby Goldmann, Tobias Ederhof, Andre Koltermann, Anja Wienecke, Andreas Schwienhorst, Manfred Eigen · 1997 · Review of Scientific Instruments
- Chemical replicationJames P. Ferris · 1994 · Nature
- Pandemic influenza viruses: time to recognize our inability to predict the unpredictable and stop dangerous gain‐of‐function experimentsSimon Wain–Hobson · 2013 · EMBO Molecular Medicine
- Pushing the Limits of Nucleic Acid FunctionEdward A. Curtis · 2022 · Chemistry - A European Journal
- Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragmentJoseph A. Piccirilli, Yelena Koldobskaya · 2011 · Philosophical Transactions of the Royal Society B Biological Sciences
- In Vitro Selected Receptors Rationalized: The First 3D Structures of RNA Aptamer/Substrate ComplexesMartin Egli · 1997 · Angewandte Chemie International Edition in English
- Designer enzymesMichael P. Robertson, William G. Scott · 2007 · Nature
- A hypothesis: Reciprocal information transfer between oligoribonucleotides and oligopeptides in prebiotic molecular evolutionShuguang Zhang, Martin Egli · 1994 · Origins of Life and Evolution of Biospheres
- Wie in vitro selektierte RNA‐Aptamere funktionieren – die räumlichen Strukturen von Substrat‐RNA‐Aptamer‐KomplexenMartin Egli · 1997 · Angewandte Chemie
- A Quarter Century of In Vitro SelectionYingfu Li · 2015 · Journal of Molecular Evolution
- Origins and Early Evolution of the RibosomeFox, George E. · 2016 · Evolution of the Protein Synthesis Machinery and Its Regulation
- A Microarray-Based Method to Perform Nucleic Acid SelectionsOlga Aminova, Matthew David Disney · 2010 · Methods in molecular biology
- DNA enzymes: New-found chemical reactivityJames K. Bashkin · 1997 · Current Biology
- Insertion of a Water Oxygen Atom into a Phosphorus−Metal Bond: From a P-Coordinated (Diphenylphosphino)alkyne to a Coordinated η2(O,C)-Vinyldiphenylphosphine Oxide†Elmostafa Louattani, Isabel Moldes, Joan Suades, J. Francesc Piniella, Ángel Álvarez‐Larena · 1998 · Organometallics
- A Model of the Origin of Life and Perspectives in Supramolecular EngineeringHans Jochen Kuhn, J. Waser · 1994 · Perspectives in supramolecular chemistry
- New Biocatalysts via Chemical ModificationIan M. Bell, Donald Hilvert · 1994 · Perspectives in supramolecular chemistry
- Synthetische Ribozyme und das erste DesoxyribozymPetra Burgstaller, Michael Famulok · 1995 · Angewandte Chemie
- Principles of in vitro selection of ribozymes from random sequence librariesPaul G. Higgs, Ulrich F. Muller · 2025 · Journal of The Royal Society Interface
- RNA Through Time: From the Origin of Life to Therapeutic Frontiers in Transcriptomics and Epitranscriptional MedicineCecilia Martinez Campos, Humberto Lanz‐Mendoza, Jorge Cime‐Castillo, Óscar Peralta-Zaragoza, Vicente Madrid‐Marina · 2025 · International Journal of Molecular Sciences
- A ribozyme that uses lanthanides as cofactorKevin J. Sweeney, Han Xu, Ulrich F. Müller · 2023 · Nucleic Acids Research
- Ancient RNA worldAlexander S. Spirin · 2010 · Paleontological Journal
- RNA made in its own mirror imageSandip A. Shelke, Joseph A. Piccirilli · 2014 · Nature
- Low Selection Pressure Aids the Evolution of Cooperative Ribozyme Mutations in CellsZhaleh N. Amini, Ulrich F. Müller · 2013 · Journal of Biological Chemistry
- Thin-film technology for direct visual detection of nucleic acid sequences: applications in clinical researchROBERT D. JENISON, Richard Bucala, Diana Maul, David C. Ward · 2005 · Expert Review of Molecular Diagnostics
- Heuristic algorithms in evolutionary computation and modular organization of biological macromolecules: Applications to in vitro evolutionAlexander V. Spirov, Мясникова Екатерина Марковна · 2022 · PLoS ONE
- Origins for EveryoneAndrew D. Ellington · 2012 · Evolution Education and Outreach
- Can Synthetic Biology Shed Light on the Origins of Life?Christophe Malaterre · 2009 · Biological Theory
- A Polyaddition Model for the Prebiotic Polymerization of RNA and RNA-Like PolymersAlex Spaeth, Mason Hargrave · 2020 · Life
- Germline Double-Strand Break Repair and Gene Targeting in Drosophila: A Trajectory System throughout EvolutionDirk‐Henner Lankenau · 2006 · Springer eBooks
- Darwin’s concepts in a test tube: Parallels between organismal and in vitro evolutionCarolina Díaz Arenas, Niles Lehman · 2008 · The International Journal of Biochemistry & Cell Biology
- Prebiotic Inhibitory Activity of Protein-Like Molecules to the Template-Directed Formation of Oligoguanylate from Guanosine 5′-Monophosphate 2-Methylimidazolide on a Polycytidylic Acid TemplateKunio Kawamura, Kazuhiro Kuranoue, Minoru Nagahama · 2004 · Bulletin of the Chemical Society of Japan
- Kinetics and Mechanism of RNA Binding by Triplex Tethered Oligonucleotide ProbesArikha C. Moses, Alanna Schepartz · 1997 · Journal of the American Chemical Society
- In Vitro Selection of Ligase Ribozymes Containing 2'-Amino GroupsNaozumi Teramoto, Yukio Imanishi, Yoshihiro Ito · 2000 · Journal of Bioactive and Compatible Polymers
- Nucleic Acids for Reagentless BiosensorsManjula Rajendran, Andrew D. Ellington · 2002 · Elsevier eBooks
- Ribozymes, recognition and evolutionBrent L. Iverson · 1995 · Chemistry & Biology
- Geochemical Origins of LifeRobert M. Hazen · 2012 · Wiley eBooks