Cited by 689Retinal Development and DisordersCircadian rhythm and melatoninCellular transport and secretion

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Rod Outer Segment Disk Shedding in Rat Retina: Relationship to Cyclic Lighting

LaVail, Matthew M.·1976·Science

Abstract

When albino rats are reared in cyclic light, a burst of rod outer segment disk shedding occurs in the retina soon after the onset of light. The number of large packets of outer segment disks (phagosomes) in the pigment epithelium at this time is 2.5 to 5 times greater than at any other time of day or night. The subsequent degradation of large phagosomes to smaller structures within pigment epithelial cells proceeds rapidly. The burst of disk shedding follows a circadian rhythm for at least 3 days, since it occurs in continuous darkness at the same time without the onset of light.

Overview

Integrity signals

Registry

Crossref · 10.1126/science.982063

Cites

20 of 20 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 20 references

Research works printed but not linked: 2

  1. Ishikawa, T., Journal of Electron Microscopy (Tokyo) 19: 85 (1970).
  2. KLEIN, D.C., NEUROSCIENCES 3 STUD: 509 (1974).

Cited by

Sorted by citations

Items 401–500 of 688

Metadata

Authors
LaVail, M. M.
Affiliations
Boston Children's Hospital (US)
Corresponding author
LaVail, Matthew M.
Venue
Science
Published
1976-12-03
Volume
194
Issue
4269
Pages
1071-1074
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2051747007
Cited by
689
References
20
Citations by year
2026: 13 · 2025: 19 · 2024: 16 · 2023: 17 · 2022: 23 · 2021: 14 · 2020: 24 · 2019: 18 · 2018: 24 · 2017: 16 · 2016: 9 · 2015: 25 · 2014: 21 · 2013: 11 · 2012: 15
FWCI
10.66
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Keywords
phagosome, retinal pigment epithelium, circadian rhythm, albino rats, photoreceptors
MeSH terms
Animals, Circadian Rhythm, Light, Organoids, Phagocytosis, Photoreceptor Cells, Pigment Epithelium of Eye, Reserpine, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review