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Cited by 245

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides

Open access
Wu, Meng, McNulty, Nathan P., Rodionov, Dmitry A., Khoroshkin, Matvei S., Griffin, Nicholas W., Cheng, Jiye, Latreille, Phil, Kerstetter, Randall A., Terrapon, Nicolas, Henrissat, Bernard, Osterman, Andrei L., Gordon, Jeffrey I.·2015·Science

Abstract

Diet shapes host and gut microbe fitness: The human gut microbiota is hugely diverse, with many strain variants having a multiplicity of effects on host metabolism and immunity. To define some of these functions, Wu et al. made libraries of mutants of Bacteroides species known for their capacity to process otherwise intractable dietary fiber. Germ-free mice colonized with defined gut microbiota communities containing the mutants were fed specific diets containing different ratios of fat and fiber. Genes, strains, and species were identified that were associated with specific metabolic pathways. The community responses to dietary shifts were manipulated in an attempt to characterize species for their probiotic or therapeutic potential. Science , this issue 10.1126/science.aac5992 >

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Metadata

Authors
Wu, M., McNulty, N. P., Rodionov, D. A., Khoroshkin, M. S., Griffin, N. W., Cheng, J., Latreille, P., Kerstetter, R. A., Terrapon, N., Henrissat, B., Osterman, A. L., & Gordon, J. I.
Venue
Science
Published
2015-10-02
Volume
350
Issue
6256
Pages
aac5992-aac5992
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1945011216
Cited by
245
References
10
FWCI
9.26
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides. https://app.cochat.ai/papers/10.1126/science.aac5992
The paper
Wu, M., McNulty, N. P., Rodionov, D. A., Khoroshkin, M. S., Griffin, N. W., Cheng, J., Latreille, P., Kerstetter, R. A., Terrapon, N., Henrissat, B., Osterman, A. L., & Gordon, J. I. (2015). Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides. Science. https://doi.org/10.1126/science.aac5992

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.