Cited by 250Insect and Arachnid Ecology and BehaviorNeurobiology and Insect Physiology ResearchEpigenetics and DNA Methylation

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus

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Abstract

Epigenetic control of caste-specific foraging: In carpenter ants, separate behavioral classes, known as castes, are determined by the epigenetic regulation of genes. Simola et al. treated ants of different castes with drugs that affected histone acetylation. Reducing histone acetylation stimulated scouting and foraging behavior. The foraging and scouting behaviors of young ants were permanently changed by directly injecting their brains with histone acetylation inhibitors. Science , this issue p. 10.1126/science.aac6633

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Metadata

Authors
Simola, D. F., Graham, R. J., Brady, C. M., Enzmann, B. L., Desplan, C., Ray, A., Zwiebel, L. J., Bonasio, R., Reinberg, D., Liebig, J., & Berger, S. L.
Affiliations
  • University of Pennsylvania (US)
  • Arizona State University (US)
  • New York University (US)
  • University of California, Riverside (US)
  • Vanderbilt University (US)
Corresponding author
  • Simola, Daniel F.
  • Graham, Riley J.
  • Reinberg, Danny
  • Liebig, Jürgen
  • Berger, Shelley L.
Venue
Science
Published
2016-01
Volume
351
Issue
6268
Pages
aac6633-aac6633
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2207623969
Cited by
242
References
55
Citations by year
2026: 10 · 2025: 18 · 2024: 24 · 2023: 22 · 2022: 21 · 2021: 30 · 2020: 31 · 2019: 21 · 2018: 19 · 2017: 27 · 2016: 19
FWCI
14.81
Type
journal article
Language
en
Open access
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • Howard Hughes Medical Institute (2009005)
  • NIH (T32HD083185, DP2MH107055)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect and Arachnid Ecology and Behavior
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
Keywords
epigenetic reprogramming, Camponotus floridanus, carpenter ants, histone acetylation, histone deacetylase, Rpd3, foraging behavior, worker caste, eusocial insects, behavioral plasticity, brain transcriptome, chromatin
MeSH terms
Acetylation, Animals, Ants, Behavior, Animal, Chromatin, Protein Processing, Post-Translational, Social Behavior, Epigenesis, Genetic, Histone Deacetylase 2, Histone Deacetylase Inhibitors, Transcriptome

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