Identification and characterization of essential genes in the human genome

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Items 601–700 of 1,004

1. Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution
   Jimmy Van den Eynden, Swaraj Basu, Erik Larsson · 2016 · PLoS Genetics
2. A permutation-based non-parametric analysis of CRISPR screen data
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3. CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide
   Simran Jeet Kaur, Zubaidah M. Ramdzan, Marie‐Christine Guiot, Li Li, Lam Leduy, Dindial Ramotar, Siham Sabri, Bassam Abdulkarim, Alain Nepveu · 2017 · Neuro-Oncology
4. Molecular Identities and ATP Release Activities of Two Types of Volume-Regulatory Anion Channels, VSOR and Maxi-Cl
   Yasunobu Okada, Toshiaki Okada, Md. Rafiqul Islam, Ravshan Z. Sabirov · 2018 · Current topics in membranes
5. Defining Essentiality Score of Protein-Coding Genes and Long Noncoding RNAs
   Pan Zeng, Ji Chen, Yuhong Meng, Yuan Zhou, Jichun Yang, Qinghua Cui · 2018 · Frontiers in Genetics
6. Pooled Lentiviral CRISPR-Cas9 Screens for Functional Genomics in Mammalian Cells
   Michael Aregger, Megha Chandrashekhar, Amy H.Y. Tong, Katherine Chan, Jason Moffat · 2018 · Methods in molecular biology
7. Microtubule End-Clustering Maintains a Steady-State Spindle Shape
   Christina L. Hueschen, Vahe Galstyan, Meelad Amouzgar, Rob Phillips, Sophie Dumont · 2019 · Current Biology
8. CRISPR-Cas9 Screening of Kaposi’s Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells
   Marion Gruffaz, Hongfeng Yuan, Wen Meng, Hui Liu, Sangsu Bae, Jin‐Soo Kim, Chun Lu, Yufei Huang, Shou‐Jiang Gao · 2019 · mBio
9. Unbiased Boolean analysis of public gene expression data for cell cycle gene identification
   Sarah A. Dabydeen, Arshad B. Desai, Debashis Sahoo · 2019 · Molecular Biology of the Cell
10. Deoxythymidylate kinase, DTYMK, is a novel gene for mitochondrial DNA depletion syndrome
    Ching‐Wan Lam, Wai-lan Yeung, Tsz-ki Ling, Ka-chung Wong, Chun Yiu Law · 2019 · Clinica Chimica Acta
11. MYC predetermines the sensitivity of gastrointestinal cancer to antifolate drugs through regulating TYMS transcription
    Tingting Liu, Yumin Han, Chunhong Yu, Yan Ji, Changxu Wang, Xiaomin Chen, Xiang Wang, Jiayan Shen, Yongfeng Zhang, Jing‐Yu Lang · 2019 · EBioMedicine
12. The essentiality landscape of cell cycle related genes in human pluripotent and cancer cells
    Ruth Viner‐Breuer, Atilgan Yilmaz, Nissim Benvenisty, Michal Goldberg · 2019 · Cell Division
13. Essential Genes of the Parasitic Apicomplexa
    Jenna Oberstaller, Thomas D. Otto, Julian C. Rayner, John H. Adams · 2021 · Trends in Parasitology
14. Combinatorial CRISPR/Cas9 Screening Reveals Epistatic Networks of Interacting Tumor Suppressor Genes and Therapeutic Targets in Human Breast Cancer
    Xiaoyu Zhao, Jinyu Li, Zhimin Liu, Scott Powers · 2021 · Cancer Research
15. Emerging Roles of Repetitive and Repeat-Containing RNA in Nuclear and Chromatin Organization and Gene Expression
    Giuseppe Trigiante, Nerea Blanes Ruiz, Andrea Cerase · 2021 · Frontiers in Cell and Developmental Biology
16. High-throughput methods for genome editing: the more the better
    Yong Huang, Meiqi Shang, Tingting Liu, Kejian Wang · 2022 · PLANT PHYSIOLOGY
17. Growing and dividing: how O-GlcNAcylation leads the way
    Harmony Ivanna Saunders, Wagner B. Dias, Chad M Slawson · 2023 · Journal of Biological Chemistry
18. The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks
    Bert van de Kooij, Fenna J. van der Wal, Magdalena B. Rother, Wouter W. Wiegant, Pau Creixell, Merula Stout, Brian A. Joughin, Julia Vornberger, Matthias Altmeyer, Marcel A.T.M. van Vugt et al. · 2024 · Nature Communications
19. Hexokinase 2 Is Targetable for HK1-Negative, HK2-Positive Tumors from a Wide Variety of Tissues of Origin
    Shili Xu, Arthur B. Catapang, Hanna M. Doh, Nicholas A. Bayley, Jason T. Lee, Daniel Braas, Thomas G. Graeber, Harvey R. Herschman · 2018 · Journal of Nuclear Medicine
20. Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes
    Lin Xu, Yanbin Zheng, Jing Liu, Dinesh Rakheja, Sydney Singleterry, Theodore Willis Laetsch, Jack F. Shern, Javed Iqbal Khan, Timothy Junius Triche, Douglas S. Hawkins et al. · 2018 · Cell Reports
21. A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion
    Joseph S. Park, Jennifer D. Helble, Jacob E. Lazarus, Guanhua Yang, Carlos J. Blondel, John G. Doench, Michael N. Starnbach, Matthew K. Waldor · 2018 · iScience
22. Rare versus common diseases: a false dichotomy in precision medicine
    Brian Hon‐Yin Chung, Jeffrey Fong Ting Chau, Gane Ka‐Shu Wong · 2021 · npj Genomic Medicine
23. RNA helicase, DDX3X, is actively recruited to sites of DNA damage in live cells
    Michael J. Cargill, Alicia J. Morales, Shashidhar Ravishankar, Edus Houston Warren · 2021 · DNA repair
24. ATG2 and VPS13 proteins: molecular highways transporting lipids to drive membrane expansion and organelle communication
    David G. McEwan, Kevin M. Ryan · 2021 · FEBS Journal
25. Induction of DISE in ovarian cancer cells in vivo
    Andrea E. Murmann, Kaylin Marie McMahon, Ashley Haluck-Kangas, Nandini Ravindran, Monal Patel, Calvin Law, Sonia Brockway, Jian‐Jun Wei, Colby Shad Thaxton, Marcus E. Peter · 2017 · Oncotarget
26. Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines
    Charles H. Adelmann, Tim Wang, David M. Sabatini, Eric S. Lander · 2018 · Methods in molecular biology
27. Inactivation of NF1 Promotes Resistance to EGFR Inhibition in KRAS/NRAS/BRAFV600 -Wild-Type Colorectal Cancer
    Alexandros Georgiou, Adam Stewart, David Cunningham, Udai Banerji, Steven R. Whittaker · 2020 · Molecular Cancer Research
28. Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function
    Brooke C. Wilson, Lena Boehme, Ambra Annibali, Alan Hodgkinson, Thomas S. Carroll, Rebecca J. Oakey, Vlad C. Seitan · 2020 · Nature Communications
29. CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments
    Qingyi Cao, Jian Ma, Chen-Hao Chen, Han Xu, Zhi Chen, Wei Li, X. Shirley Liu · 2017 · PLoS ONE
30. An Integrated Model of Minor Intron Emergence and Conservation
    Marybeth Baumgartner, Kyle D. Drake, Rahul Kanadia · 2019 · Frontiers in Genetics
31. Combined targeting of G protein‐coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN‐null triple negative breast cancer
    Davide Zecchin, Christopher Moore, Fanourios Michailidis, Stuart D. Horswell, Sareena Rana, Michael T. Howell, Julian Downward · 2020 · EMBO Molecular Medicine
32. CRISPR Tools for Systematic Studies of RNA Regulation
    J Engreitz, Omar O. Abudayyeh, Jonathan S. Gootenberg, Feng Zhang · 2019 · Cold Spring Harbor Perspectives in Biology
33. Recent advances in the characterization of essential genes and development of a database of essential genes
    Ya‐Ting Liang, Hao Luo, Yan Lin, Feng Gao · 2024 · iMeta
34. Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
    Goran Tomić, Clare Sheridan, Alice Yunsi Refermat, Marc P. Baggelaar, James Sipthorp, Bhuvana Sudarshan, Cory A. Ocasio, Alejandro Suárez‐Bonnet, Simon Lawrence Priestnall, Eleanor Herbert et al. · 2024 · Cell Reports
35. RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation
    Zezhao Chen, Xiaosong Gu, Hongbo Chen, Huijing Zhang, Jianping Liu, Xiaohua Yang, Yuping A. Cai, Mengmeng Zhang, Lingjie Yan, Yuanxin Yang et al. · 2025 · Cell Metabolism
36. Post genome-wide association analysis: dissecting computational pathway/network-based approaches
    Emile Rugamika Chimusa, Shareefa Dalvie, Collet Dandara, Ambroise Wonkam, Gaston K. Mazandu · 2018 · Briefings in Bioinformatics
37. Modulation of Early Mitotic Inhibitor 1 (EMI1) depletion on the sensitivity of PARP inhibitors in BRCA1 mutated triple-negative breast cancer cells
    Dina Moustafa, Maha R. Abd Elwahed, Hanaa H. Elsaid, Jeffrey D. Parvin · 2021 · PLoS ONE
38. Differential requirements for the CENP-O complex reveal parallel PLK1 kinetochore recruitment pathways
    Alexandra L. Nguyen, Marie Diane Fadel, Iain M. Cheeseman · 2021 · Molecular Biology of the Cell
39. Harnessing model organism genomics to underpin the machine learning-based prediction of essential genes in eukaryotes – Biotechnological implications
    Túlio de Lima Campos, Pasi K. Korhonen, Andreas Hofmann, Robin B. Gasser, Neil David Young · 2021 · Biotechnology Advances
40. Ligand Recognition by the Lipid Transfer Domain of Human OSBP Is Important for Enterovirus Replication
    Jun Kobayashi, Minetaro Arita, Shota Sakai, Hirotatsu Kojima, Miki Senda, Toshiya Senda, Kentaro Hanada, Ryuichi Kato · 2022 · ACS Infectious Diseases
41. Paralog Explorer: A resource for mining information about paralogs in common research organisms
    Yanhui Hu, Ben Ewen‐Campen, Aram Comjean, Jonathan Rodiger, Stephanie Elizabeth Mohr, Norbert Perrimon · 2022 · Computational and Structural Biotechnology Journal
42. The DNA repair function ofCUX1contributes to radioresistance
    Zubaidah M. Ramdzan, Vasudeva Ginjala, Jordan B. Pinder, Dudley Chung, Caroline M. Donovan, Simran Jeet Kaur, Lam Leduy, Graham Dellaire, Shridar Ganesan, Alain Nepveu · 2017 · Oncotarget
43. Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer
    Marise R. Heerma van Voss, Farhad Vesuna, Guus Martinus Bol, Jan Meeldijk, Ana Raman, G. Johan A. Offerhaus, Horst Buerger, Arvind H. Patel, Elsken van der Wall, P. J. van Diest et al. · 2017 · OncoTargets and Therapy
44. Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective Rnpc3-deficient mice
    Karen Doggett, Ben B. Williams, Sebastian Markmiller, Fan‐Suo Geng, Janine L. Coates, Stephen Mieruszynski, Matthias Ernst, Tim Thomas, Joan K. Heath · 2018 · RNA
45. CD95/Fas ligand mRNA is toxic to cells
    William Putzbach, Ashley Haluck-Kangas, Quan Q. Gao, Aishe A. Sarshad, Elizabeth T. Bartom, Austin M. Stults, Abdul S. Qadir, Markus Hafner, Marcus E. Peter · 2018 · eLife
46. A CRISPR/Cas9 guidance RNA screen platform for HIV provirus disruption and HIV/AIDS gene therapy in astrocytes
    Zaohua Huang, Madahavan Nair · 2017 · Scientific Reports
47. Genome-Wide CRISPR Screening Identifies JAK1 Deficiency as a Mechanism of T-Cell Resistance
    Ping Han, Qiang Dai, Lilv Fan, Hao Ran Lin, Xiaoqing Zhang, Fanlin Li, Xuanming Yang · 2019 · Frontiers in Immunology
48. Nopp140-mediated concentration of telomerase in Cajal bodies regulates telomere length
    Jonathan Bizarro, Amit Bhardwaj, Susan Harless Smith, U. Thomas Meier · 2019 · Molecular Biology of the Cell
49. Genomics and Functional Genomics of Malignant Pleural Mesothelioma
    Ece Çakıroğlu, Şerif Şentürk · 2020 · International Journal of Molecular Sciences
50. CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens
    Alessandro Vinceti, Emre Karakoç, Clare Pacini, Umberto Perron, Riccardo Roberto De Lucia, Mathew J. Garnett, Francesco Iorio · 2021 · BMC Genomics
51. Double stranded DNA breaks and genome editing trigger loss of ribosomal protein RPS27A
    Celeste Riepe, Elena Zelin, Phillip Andrew Frankino, Zuriah A. Meacham, Samantha G. Fernandez, Nicholas T. Ingolia, Jacob E. Corn · 2021 · FEBS Journal
52. A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
    L. Donohue, M. Guo, Yang Zhao, N. Jung, Rose T. Bussat, D. S. Kim, Poornima H. Neela, Laura N. Kellman, Omar S. Garcia, R. Meyers et al. · 2022 · Cell Genomics
53. CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing
    Emanuela Kerschbamer, Michele Arnoldi, Takshashila Tripathi, Miguel Pellegrini, Samuele Maturi, Serkan Erdin, Elisa Salviato, Francesca Di Leva, Endre Sebestyén, Erik Dassi et al. · 2022 · Nucleic Acids Research
54. Recognition of the CCT5 di‐Glu degron by CRL4DCAF12 is dependent on TRiC assembly
    Carlos Pla‐Prats, Simone Cavadini, Georg Kempf, Nicolas H. Thomä · 2023 · The EMBO Journal
55. Novel tRNA function in amino acid sensing of yeast Tor complex1
    Yoshiaki Kamada · 2017 · Genes to Cells
56. High-throughput genetic screens using CRISPR–Cas9 system
    Jiyeon Kweon, Yongsub Kim · 2018 · Archives of Pharmacal Research
57. Cytosine Base Editor (hA3A-BE3-NG)-Mediated Multiple Gene Editing for Pyramid Breeding in Pigs
    Yu Wang, Dengfeng Bi, Guosong Qin, Ruigao Song, Jing Tao Yao, Chunwei Cao, Qiantao Zheng, Naipeng Hou, Yanfang Wang, Jianguo Zhao · 2020 · Frontiers in Genetics
58. Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22
    Justin T. Marinko, Madison T. Wright, Jonathan P. Schlebach, Katherine R. Clowes, Darren R. Heintzman, Lars Plate, Charles R. Sanders · 2021 · Journal of Biological Chemistry
59. Host-targeted Interventions as an Exciting Opportunity to Combat Malaria
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60. EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities
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61. Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells
    David Wu, Aunoy Poddar, Elpinickie Ninou, Elizabeth E. Hwang, Mitchel A. Cole, S. John Liu, Max A. Horlbeck, Jin Chen, Joseph M. Replogle, Giovanni A. Carosso et al. · 2022 · Cell Genomics
62. Neutrophils actively swell to potentiate rapid migration
    Tamas L Nagy, Evelyn Strickland, Orion David Weiner · 2023 · eLife
63. Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis
    I‐Li Tan, Alexendar R. Perez, Rachel J. Lew, Xiaoyu Sun, Alisha Baldwin, Yong K. Zhu, Mihir M. Shah, Mitchel Stuart Berger, Jennifer A. Doudna, Christof Fellmann · 2023 · Cell Reports
64. Higher-order protein assembly controls kinetochore formation
    Gunter B. Sissoko, Ekaterina V. Tarasovetc, Océane Marescal, Ekaterina L. Grishchuk, Iain M. Cheeseman · 2024 · Nature Cell Biology
65. Identifying mouse developmental essential genes using machine learning
    David Tian, Stephanie C. Wenlock, Mitra Kabir, George T. Tzotzos, Andrew J. Doig, Kathryn E. Hentges · 2018 · Disease Models & Mechanisms
66. Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
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67. Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning
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68. Exploring CRISPR-Cas: The transformative impact of gene editing in molecular biology
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69. Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor
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70. ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer
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71. CEN‐tools: an integrative platform to identify the contexts of essential genes
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72. Genetic and epigenetic features of promoters with ubiquitous chromatin accessibility support ubiquitous transcription of cell-essential genes
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73. Noncoding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability
    Bo Ding, Ying Liu, Zhiheng Liu, Lina Zheng, Ping Xu, Chen Zhao, Peiyao Wu, Ying Zhao, Qian Pan, Yu Guo et al. · 2021 · Science Advances
74. Microhomology-based CRISPR tagging tools for protein tracking, purification, and depletion
    Dawei Lin, Benjamin P. Chung, Jiawei Huang, Xiaorong Wang, Lan Huang, Peter Kaiser · 2019 · Journal of Biological Chemistry
75. Nopp140-chaperoned 2′-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity
    Jonathan Bizarro, Svetlana Deryusheva, Ludivine Wacheul, Varun Gupta, Felix G.M. Ernst, Denis L. J. Lafontaine, Joseph G. Gall, U. Thomas Meier · 2021 · Genes & Development
76. PerturbNet predicts single-cell responses to unseen chemical and genetic perturbations
    Yu, Hengshi, Welch, Joshua D. · 2022
77. Delivery methods for site-specific nucleases: Achieving the full potential of therapeutic gene editing
    Jia Liu, Sailan Shui · 2016 · Journal of Controlled Release
78. Large differences in proportions of harmful and benign amino acid substitutions between proteins and diseases
    Gerard C. P. Schaafsma, Mauno Vihinen · 2017 · Human Mutation
79. Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury
    Deborah Kennedy Boone, Harris A. Weisz, Min Bi, Michael T. Falduto, Karen E. O. Torres, Hannah E. Willey, Christina M. Volsko, Anjali M. Kumar, Maria‐Adelaide Micci, Douglas S. DeWitt et al. · 2017 · Scientific Reports
80. Synthetic Biology Speeds Up Drug Target Discovery
    Yixuan Xie, Yan-Fang Yang, Yu He, Xixi Wang, Peng Zhang, Haocheng Li, Shufang Liang · 2020 · Frontiers in Pharmacology
81. Construction and Analysis of a ceRNA Network Reveals Potential Prognostic Markers in Colorectal Cancer
    Li Guo, Guowei Yang, Yihao Kang, Sunjing Li, Rui Duan, Lulu Shen, Wenwen Jiang, Bowen Qian, Zibo Yin, Tingming Liang · 2020 · Frontiers in Genetics
82. Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma
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83. Noncoding <scp>RNA</scp> mutations in cancer
    Zhou, Honghong, Hao, Xinpei, Zhang, Peng, He, Shunmin · 2023 · WIREs RNA
84. Reduced intrinsic DNA curvature leads to increased mutation rate
    Chaorui Duan, Qing Huan, Xiaoshu Chen, Shaohuan Wu, Lucas B. Carey, Xionglei He, Wenfeng Qian · 2018 · Genome biology
85. Functional Genomic Characterization of Cancer Genomes
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86. A review of computational methods for predicting cancer drug response at the single-cell level through integration with bulk RNAseq data
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87. Genome-scale exon perturbation screens uncover exons critical for cell fitness
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88. Dienone Compounds: Targets and Pharmacological Responses
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89. CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs
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90. Schistosome W-Linked Genes Inform Temporal Dynamics of Sex Chromosome Evolution and Suggest Candidate for Sex Determination
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91. Accurate Prediction of Human Essential Proteins Using Ensemble Deep Learning
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92. Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
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93. Aminothiazolone Inhibitors Disrupt the Protein–RNA Interaction of METTL16 and Modulate the m6A RNA Modification
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94. Post-transcriptional regulation in hematopoiesis: RNA binding proteins take control
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95. Poxviral protein E3–altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor–stimulated immune responses
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96. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
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97. Expression-based prediction of human essential genes and candidate lncRNAs in cancer cells
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98. XPO1E571K Mutation Modifies Exportin 1 Localisation and Interactome in B-Cell Lymphoma
    Hadjer Miloudi, Élodie Bohers, François Guillonneau, Antoine Taly, Vincent Cabaud Gibouin, Pierre‐Julien Viailly, Gaëtan Jégo, Luca Grumolato, Fabrice Jardin, Brigitte Sola · 2020 · Cancers
99. Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins
    Yang, Jicheng, Guo, Fusheng, Chin, Hui San, Chen, Gao Bin, Ang, Chow Hiang, Lin, Qingsong, Hong, Wanjin, Fu, Nai Yang · 2023 · Cell Reports
100. CRISPR-gRNA Design
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