The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Mutations causing mitochondrial disease: What is new and what challenges remain?
Open accessAbstract
Mitochondrial diseases are among the most common and most complex of all inherited genetic diseases. The involvement of both the mitochondrial and nuclear genome presents unique challenges, but despite this there have been some remarkable advances in our knowledge of mitochondrial diseases over the past few years. A greater understanding of mitochondrial genetics has led to improved diagnosis as well as novel ways to prevent transmission of severe mitochondrial disease. These and other advances have had a major impact on patient care, but considerable challenges remain, particularly in the areas of therapies for those patients manifesting clinical symptoms associated with mitochondrial dysfunction and the tissue specificity seen in many mitochondrial disorders. This review highlights some important recent advances in mitochondrial disease but also stresses the areas where progress is essential.
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Cites
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Cited by
Mitochondrial dynamics in health and disease: mechanisms and potential targets
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Mammalian Mitochondria and Aging: An Update
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The genetics and pathology of mitochondrial disease
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Self-citationZinovkin, R. A., & Zamyatnin, A. A. (2019) · Current Molecular Pharmacology · doi:10.2174/1874467212666181127151059 · Cited by 209
Conservation and the Genomics of Populations
Allendorf, F. W., Funk, W. C., Aitken, S. N., Byrne, M., Luikart, G., & Antunes, A. (2022) · doi:10.1093/oso/9780198856566.001.0001 · Cited by 207
Metadata
- Authors
- Lightowlers, R. N., Taylor, R. W., & Turnbull, D. M.
- Venue
- Science
- Published
- 2015-09-25
- Volume
- 349
- Issue
- 6255
- Pages
- 1494-1499
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2268456576
- Cited by
- 341
- References
- 8
- FWCI
- 15.31
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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