The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche
Open accessAbstract
Cross-talk in the mammary gland: Macrophages engulf damaged and dead cells to clear infection, but they also participate in tissue regeneration. Chakrabarti et al. expand the macrophage repertoire for mammary gland development (see the Perspective by Kannan and Eaves). Mammary gland stem cells secrete the Notch ligand Dll1 and activate Notch signaling, which promotes survival of adjacent macrophages. This stimulates production of Wnt ligands, which signal back to the mammary gland stem cells. This cross-talk plays an important role in coordinating mammary gland development, tissue homeostasis, and, not least, breast cancer. Science , this issue p. eaan4153 ; see also p. 1401
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Cites
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
Wnt/β-catenin signaling and disease
Clevers, H., & Nusse, R. (2012) · Cell · doi:10.1016/j.cell.2012.05.012 · Cited by 5,554
Self-citationPaneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
Sato, T., van Es, J. H., Snippert, H. J., Stange, D. E., Vries, R. G., van den Born, M., Barker, N., Shroyer, N. F., van de Wetering, M., & Clevers, H. (2011) · Nature · doi:10.1038/nature09637 · Cited by 2,510
Generation of a functional mammary gland from a single stem cell
Shackleton, M., Vaillant, F., Simpson, K. J., Stingl, J., Smyth, G. K., Asselin-Labat, M.-L., Wu, L., Lindeman, G. J., & Visvader, J. E. (2006) · Nature · doi:10.1038/nature04372 · Cited by 2,005
kConFab, Lim, E., Vaillant, F., Wu, D., Forrest, N. C., Pal, B., Hart, A. H., Asselin-Labat, M.-L., Gyorki, D. E., Ward, T., et al. (2009) · Nature Medicine · doi:10.1038/nm.2000 · Cited by 1,492 · cited 1×
“Frequency of MaSCs in the transplanted cell suspension was calculated using L-calc software (StemCell Technologies) or ELDA (extreme limiting dilution assay) (30, 45).”
MethodDistinct stem cells contribute to mammary gland development and maintenance
Van Keymeulen, A., Rocha, A. S., Ousset, M., Beck, B., Bouvencourt, G., Rock, J., Sharma, N., Dekoninck, S., & Blanpain, C. (2011) · Nature · doi:10.1038/nature10573 · Cited by 854
Control of mammary stem cell function by steroid hormone signalling
Asselin-Labat, M.-L., Vaillant, F., Sheridan, J. M., Pal, B., Wu, D., Simpson, E. R., Yasuda, H., Smyth, G. K., Martin, T. J., Lindeman, G. J., et al. (2010) · Nature · doi:10.1038/nature09027 · Cited by 693 · cited 4×
“Gene set enrichment analysis (GSEA) confirmed that P4-Dll1 cells were enriched for MaSC signatures (26, 30), whereas P4-Dll1 cells were enriched for luminal signatures (Fig.”
BackgroundMethodInfluentialConditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene
Burnett, S. H., Kershen, E. J., Zhang, J., Zeng, L., Straley, S. C., Kaplan, A. M., & Cohen, D. A. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0903442 · Cited by 307
Transplantable Mouse Tumor Models of Breast Cancer Metastasis
Chakrabarti, R., & Kang, Y. (2015) · Methods in Molecular Biology · doi:10.1007/978-1-4939-2297-0_18 · Cited by 20
Self-citation
Cited by
Notch Signaling in the Tumor Microenvironment
Meurette, O., & Mehlen, P. (2018) · Cancer Cell · doi:10.1016/j.ccell.2018.07.009 · Cited by 678
Cancer stem cell–immune cell crosstalk in tumour progression
Bayik, D., & Lathia, J. D. (2021) · Nature Reviews Cancer · doi:10.1038/s41568-021-00366-w · Cited by 561
Establishment and Maintenance of the Macrophage Niche
Guilliams, M., Thierry, G. R., Bonnardel, J., & Bajenoff, M. (2020) · Immunity · doi:10.1016/j.immuni.2020.02.015 · Cited by 512
Microglia Actively remodel adult hippocampal neurogenesis through the phagocytosis secretome
Diaz-Aparicio, I., Paris, I., Sierra-Torre, V., Plaza-Zabala, A., Rodríguez-Iglesias, N., Márquez-Ropero, M., Beccari, S., Huguet, P., Abiega, O., Alberdi, E., et al. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.0993-19.2019 · Cited by 333
Tissue‐resident macrophages in omentum promote metastatic spread of ovarian cancer
Etzerodt, A., Moulin, M., Doktor, T. K., Delfini, M., Mossadegh-Keller, N., Bajenoff, M., Sieweke, M. H., Moestrup, S. K., Auphan-Anezin, N., & Lawrence, T. (2020) · Journal of Experimental Medicine · doi:10.1084/jem.20191869 · Cited by 305
Metadata
- Authors
- Chakrabarti, R., Celià-Terrassa, T., Kumar, S., Hang, X., Wei, Y., Choudhury, A., Hwang, J., Peng, J., Nixon, B., Grady, J. J., DeCoste, C., Gao, J., van Es, J. H., Li, M. O., Aifantis, I., Clevers, H., & Kang, Y.
- Venue
- Science
- Published
- 2018-06-29
- Volume
- 360
- Issue
- 6396
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2804505252
- Cited by
- 195
- References
- 9
- FWCI
- 7.69
- Type
- journal article
- Language
- en
- Open access
- green
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- Chakrabarti, R., Celià-Terrassa, T., Kumar, S., Hang, X., Wei, Y., Choudhury, A., Hwang, J., Peng, J., Nixon, B., Grady, J. J., DeCoste, C., Gao, J., van Es, J. H., Li, M. O., Aifantis, I., Clevers, H., & Kang, Y. (2018). Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche. Science. https://doi.org/10.1126/science.aan4153
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