Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice

Cited by (669)

Items 601–669 of 669

1. Genome Editing with CRISPR‐Cas Systems
   Peter Lotfy, Patrick D. Hsu · 2022 · Wiley eBooks
2. Plant Genome Editing
   Naoki Wada, Yuriko Osakabe, Keishi Osakabe · 2022 · CABI eBooks
3. Recent Advances and Application of CRISPR Base Editors for Improvement of Various Traits in Crops
   P. Sushree Shyamli, Sandhya Suranjika, Seema Pradhan, Ajay Kumar Parida · 2022 · Springer eBooks
4. Gene and base editing tools to accelerate cereal improvement
   Νικόλαος Τσακιρπάλογλου, Kurniawan Rudi Trijatmiko, Endang M. Septiningsih, Michael J. Thomson · 2023 · Elsevier eBooks
5. [Correction of the pathogenic mutation in the G6PC3 gene by adenine base editing in mutant embryos].
   M Hong, Peng Wang, Tao Shangguan, G L Li, R P Bian, Weifeng He, Wenting Jiang, Jieping Chen · 2023 · PubMed Central
6. Research progress of high precision single base editing technology with a focus on prime editing
   Jiaxin Zhang · 2023 · Theoretical and Natural Science
7. Bacterial CRISPR systems and applications
   Zhaowei Wu, Quanjiang Ji · 2024 · Elsevier eBooks
8. Additional file 12 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
   Juan Luo, Muhammad Abid, Tu, Jing, Xinxia Cai, Yi Zhang, Puxin Gao, Hongwen Huang · 2023 · Figshare
9. Additional file 2 of Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)
   Guanying Wang, Zhongping Xu, Fuqiu Wang, Yuefan Huang, Yanfeng Xin, Sijia Liang, Li, Bo, Huan Si, Lin Sun, Qiongqiong Wang et al. · 2022 · Figshare
10. Additional file 13 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Juan Luo, Muhammad Abid, Tu, Jing, Xinxia Cai, Yi Zhang, Puxin Gao, Hongwen Huang · 2023 · Figshare
11. Progress in developing and implementing CRISPR technologies made by Sun Yat-sen University
    Zhenxiang Li, Yitong Zhou, Junjiu Huang, Jianfeng Li · 2024 · Scientia Sinica Vitae
12. Generation of Inheritable A-to-G Transitions Using Adenine Base Editing and NG-PAM Cas9 in Arabidopsis thaliana
    Yi Yun Tan, Yin Yin Liew, Rachelle R.Q. Lee, Baptiste Castel, Nga Man Chan, Wei-Lin Wan, Yizhong Zhang, Donghui Hu, Persis Chan, Sang‐Tae Kim et al. · 2024 · Molecular Plant-Microbe Interactions
13. Plant genome precise editing technology-prime editing
    Suhuai Zhou, Fang Li, Juan Li, Xiaoya Wu, Dandan Wu, Rongfang Xu, Pengcheng Wei · 2024 · Chinese Science Bulletin (Chinese Version)
14. QBEmax redefines the precise base editing in crop plants
    Muhammad Waseem Sajjad, Fatima Muzamil, Rubab Zahra Naqvi, Amin Imran · 2025 · Functional & Integrative Genomics
15. Sensitive, direct detection of non-coding off-target base editor unwinding and editing in primary cells
    Tong Wang, Selin Jessa, Georgi K. Marinov, Sandy L. Klemm, Anshul Bharat Kundaje, William James Greenleaf · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
16. Tag it and bag it: A flexible method for target DNA capture using a fusion protein of CBE with UdgX
    Wenjia Pan, Yue Zhang, Xiaoping Liao, Yan-Mei Guo, Meng Wang · 2025 · Chemical Engineering Journal
17. Base editing both DNA strands in distinct editing windows with small CRISPR-associated effector Cas12f1
    Thomas Swartjes, Evgenios Bouzetos, Belén Adiego-Pérez, Victor D. Pool, Raymond H.J. Staals, John van der OOST, Wen Y. Wu · 2025 · iScience
18. Additional file 1 of Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)
    Wang, Guanying, Xu, Zhongping, Fuqiu Wang, Huang, Yuefan, Yanfeng Xin, Liang, Sijia, Li, Bo, Si, Huan, Sun, Lin, Wang, Qiongqiong et al. · 2022 · Figshare
19. Additional file 7 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
20. Additional file 2 of Versatile generation of precise gene edits in bovines using SEGCPN
    Wang, Ming, Fangrong Ding, Wang, Haiping, Ling Li, Dai, Yunping, Sun, ZhaoLin, Ning Li · 2024 · Figshare
21. Additional file 9 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
22. Additional file 4 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
23. Additional file 3 of Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)
    Wang, Guanying, Xu, Zhongping, Fuqiu Wang, Huang, Yuefan, Yanfeng Xin, Liang, Sijia, Li, Bo, Si, Huan, Sun, Lin, Wang, Qiongqiong et al. · 2022 · Figshare
24. Additional file 3 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
25. Additional file 8 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
26. Additional file 4 of Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice
    Zongyi Yi, Yanxia Zhao, Zexuan Yi, Yongjian Zhang, Tang Gangbin, Zhang, Xiaoxue, Huixian Tang, Zhang, Wei, Zhao, Ying, Huayuan Xu et al. · 2024 · Figshare
27. Additional file 1 of Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice
    Zongyi Yi, Zhao, Yanxia, Zexuan Yi, Yongjian Zhang, Tang Gangbin, Zhang, Xiaoxue, Huixian Tang, Zhang, Wei, Zhao, Ying, Huayuan Xu et al. · 2023 · Figshare
28. Additional file 10 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
29. Additional file 6 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
30. Additional file 1 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
31. Additional file 1 of Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform
    Christophe Gaillochet, Alexandra Peña Fernández, Vera Goossens, Katelijn D’Halluin, Andrzej Drozdzecki, Myriam Shafie, Van Duyse, Julie, Gert Van Isterdael, Camila Gonzalez, Mattias Vermeersch et al. · 2023 · Figshare
32. Additional file 2 of Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice
    Zongyi Yi, Yanxia Zhao, Zexuan Yi, Yongjian Zhang, Tang Gangbin, Zhang, Xiaoxue, Huixian Tang, Zhang, Wei, Zhao, Ying, Huayuan Xu et al. · 2024 · Figshare
33. Additional file 3 of Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice
    Zongyi Yi, Yanxia Zhao, Zexuan Yi, Yongjian Zhang, Tang Gangbin, Zhang, Xiaoxue, Huixian Tang, Zhang, Wei, Zhao, Ying, Huayuan Xu et al. · 2024 · Figshare
34. Additional file 10 of Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform
    Christophe Gaillochet, Alexandra Peña Fernández, Vera Goossens, Katelijn D’Halluin, Andrzej Drozdzecki, Myriam Shafie, Van Duyse, Julie, Gert Van Isterdael, Camila Gonzalez, Mattias Vermeersch et al. · 2023 · Figshare
35. Additional file 2 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
36. Additional file 11 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
37. Additional file 1 of Versatile generation of precise gene edits in bovines using SEGCPN
    Wang, Ming, Fangrong Ding, Wang, Haiping, Li, Ling, 蕴平 戴, Sun, ZhaoLin, Ning Li · 2023 · Figshare
38. Additional file 5 of Cytosine base editors (CBEs) for inducing targeted DNA base editing in Nicotiana benthamiana
    Luo, Juan, Muhammad Abid, Jing Tu, Xinxia Cai, Zhang, Yi, Gao, Puxin, Huang, Hongwen · 2023 · Figshare
39. Exploring the Efficiency of Multi-Target Editing with Single Base Editors in Haematopoietic Cell lines
    Ariel Simpson, Sandy S. C. Hung, Pamodha Somasiri, Rajendra KC, Thomas Guinan, Alexander Barnett, Alex William Hewitt, Kirsten A. Fairfax · 2026 · Research Square
40. Therapeutic Genome Engineering for the Treatment of Sickle Cell Disease
    Alexis Kristine Leonard, Akshay Sharma, Fang-Yun Chao, Jonathan S. Yen · 2026 · Springer eBooks
41. Dissecting multi-gene virulence phenotypes with base editing requires consideration of target-independent mutagenesis
    Joshua P. M. Newson, Sandra Gawlitt, Sneha Sundar, Roland R. Regoes, Chase L. Beisel, Wolf‐Dietrich Hardt · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
42. DNA-free genome editing in Solanaceae: an evidence-based roadmap from transformation to field and regulatory readiness
    Ying Qin, Wenwen Si, Chengchuang Huang · 2026 · Plant Biotechnology Reports
43. A simplified RUBY reporter-enabled hairy-root system for rapid evaluation of genome editing and gene function in grapevine
    Chong Ren, Yanping Lin, Mohamed Salaheldin Mokhtar Mohamed, Chencong Liu, Zhenchang Liang · 2026 · Planta
44. Vers le développement d'une nouvelle approche pour étudier les mécanismes moléculaires impliqués dans la formation des aérenchymes racinaires chez le riz
    Hans Mounier · 2019
45. Base editing approaches for the treatment of ß-hemoglobinopathies
    Giulia Hardouin · 2022
46. Genome and epigenome editing approaches to treat β-hemoglobinopathies
    Letizia Fontana · 2024
47. CRISPR-Cas9-based strategies for enhanced targeted integration
    Laurie Lacombe · 2024
48. Establishment of an Efficient Protoplast-Based Base Editing Platform in Lettuce
    Yu Jia, Guo Peng, Qiang Zhou · 2026 · Agronomy
49. Inducible, split base editors for in vivo cancer functional genomics
    Diqiu Ren, Shangshang Wang, Keisuke Yamada, Yuqiao Liu, Robert Hapke, Aktan Alpsoy, Yugong Ho, Canjing Zhang, Yemin Lan, Shuo Zhang et al. · 2026 · Nature Biotechnology
50. Engineering TadA8e-based base editors for GhWOX1 editing to create cotton with diverse leaf shapes
    Guanying Wang, Shihe Jiang, Meijing Li, Yao He, Mingju Zhu, Fengjiao Hui, Li Yang, Jie Yu, Yongxue Hu, Mengqin Tang et al. · 2026 · Science China Life Sciences
51. Gene therapy development for retinal diseases
    Felix F. Reichel, Julia-Sophia Bellingrath, Petèr Király, M. DOMINIK FISCHER · 2026 · Handbook of clinical neurology
52. Synergistic Use of Site-Specific Recombination and CRISPR-Cas Platforms for Complex Plant Genome Engineering
    Yuan‐Yeu Yau, Zhiguo Han, Ashwani Kumar · 2025 · LS International Journal of Life Sciences
53. Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing
    Linsha Ma, Pengcheng Yao, S S Wu, Y F Shi, Lang Qin, Li B, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yang Song et al. · 2026 · Advanced Science
54. CRISPR–Cas-enabled accelerated breeding pipelines for engineering climate-resilient crops under abiotic stress conditions
    Aditi Dutt, Arnika Keithellakpam, Adity Laskar, Anita Kachari, Channakeshavaiah Chikkaputtaiah, Banashree Saikia · 2026 · Elsevier eBooks
55. Editing around the target: epitope engineering to protect stem cell grafts
    Joanne Seoyoung Baek, Gabriele Casirati, Pietro Genovese, Saar I. Gill · 2026 · Blood Advances
56. Synonymous mutations in essential genes infrequently produce fitness effects in human cell lines
    Yiyun Rao, Ivan Sokirniy, Edward P. O’Brien, Justin R. Pritchard · 2026 · Nucleic Acids Research
57. Differential condensation of FLO6 influences grain amylose synthesis in rice
    Fei Liu, Minghao Zhang, Zhipeng Yan, Huang Yifei, Hui Zhang, Jing Zhang, Kabin Xie, Yibo Li, Yuqing He, Deqiang Duanmu et al. · 2026 · Science Advances
58. Interplay Between Base Editing and DNA repair: From Molecular Mechanisms to Clinical Translation
    Rui Tao, Min Li, Tongyun Luo, Shaohua Yao · 2026 · Biotechnology Advances
59. A portable recalibration workflow for reference-based variant calling in non-human genomes
    Hyeonjung Lee, Sunhee Kim, Michelle Audrelia Sunartha, Chang-Yong Lee, Young-Suk Lee · 2026 · PLoS Computational Biology
60. AI-guided CRISPR in crop yield enhancement
    Elshan Musazade, Isack Ibrahim Mrisho, Diming Zhang, Jinshan Gao, Zhiyuan Cheng, Xianzhong Feng · 2026 · Elsevier eBooks
61. Gene editing beyond food crops
    Sohini Jash, Deepak Kumar Upadhyay, Ansu Chetri, Ramsha Syed, Sayanti Mandal · 2026 · Elsevier eBooks
62. Machine learning approaches in gene editing
    Mohamed A. M. Atia, Abdelghani Belgaid, Kamel A. Abd-Elsalam, Achraf El Allali · 2026 · Elsevier eBooks
63. SpacerScope: binary-vectorized, genome-wide off-target profiling for RNA-guided nucleases without prior candidate-site bias
    Yanji Qu, Yaxuan Wang, Yan Wang, Haoru Tang, Qing Chen · 2026 · Briefings in Bioinformatics
64. MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts
    Shaoshuai Wang, Yu Wang, Dengfeng Bi, Jianguo Zhao, Yue Wang · 2026 · Animal Research and One Health
65. Engineered Transformer Base Editor with Enhanced Editing Efficiency
    Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu · 2026 · Advanced Science
66. Precision genetic manipulation: CRISPR toolkits reshape plant biology
    Zhenxiang Li, Xiangyu Xiong, Renqi Cao, Jianfeng Li · 2026 · PLANT PHYSIOLOGY
67. The CRISPR/Cas technology landscape: From molecular mechanisms to multidisciplinary applications
    Zhenzhen Liu, Yutian Yang, Zhihao Li, Pengkun Li, Junru Jia, Xi Qiao, Yi Su, Yuming Qin, Haiqiang Wang, Yuanyuan Dai et al. · 2026 · Genes & Diseases
68. From base transitions to expanded editing tools: development and applications of plant base editors
    Ning Sui, Jiekun Zhang, Wenyue Xu, 庞美新, Ruixiang Zhang, Nan Chai, Jun Wen, Taoli Liu, Zhiye Zheng, Jingyang Huang et al. · 2026 · Biotechnology Advances
69. Beyond prediction: The evolving role of artificial intelligence in genome editing
    Soochul Shin, Heesoo Uhm, Yong-Woo Kim, Hyeon Woo Im, Sangsu Bae · 2026 · Molecular Cell