Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice

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Multiplex precise base editing in cynomolgus monkeys

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A Tale of Two Moieties: Rapidly Evolving CRISPR/Cas-Based Genome Editing

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Can We Use Gene-Editing to Induce Apomixis in Sexual Plants?

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Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice

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Base editing and prime editing in laboratory animals

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Derepression of specific miRNA-target genes in rice using CRISPR/Cas9

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Revolutionising healing: Gene Editing's breakthrough against sickle cell disease

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Discriminated sgRNAs-Based SurroGate System Greatly Enhances the Screening Efficiency of Plant Base-Edited Cells

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Amelioration of an Inherited Metabolic Liver Disease through Creation of a De Novo Start Codon by Cytidine Base Editing

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Quadruple adenine base–edited allogeneic CAR T cells outperform CRISPR/Cas9 nuclease–engineered T cells

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A large-scale genome and transcriptome sequencing analysis reveals the mutation landscapes induced by high-activity adenine base editors in plants

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Gene Editing Technologies to Target HBV cccDNA

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TadA reprogramming to generate potent miniature base editors with high precision

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Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice

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Engineering APOBEC3A deaminase for highly accurate and efficient base editing

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Development of an Efficient C-to-T Base-Editing System and Its Application to Cellulase Transcription Factor Precise Engineering in Thermophilic Fungus Myceliophthora thermophila

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AcrIIA5 Suppresses Base Editors and Reduces Their Off-Target Effects

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Engineering disease-resistant plants with alternative translation efficiency by switching uORF types through CRISPR

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CRISPR-Based Therapeutic Gene Editing for Duchenne Muscular Dystrophy: Advances, Challenges and Perspectives

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Split complementation of base editors to minimize off-target edits

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Breaking genetic shackles: The advance of base editing in genetic disorder treatment

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Enhancing resistance to bacterial blight in rice using CRISPR-based base editing technology

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Treating neuromuscular diseases: unveiling gene therapy breakthroughs and pioneering future applications

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Crop breeding – From experience-based selection to precision design

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The potential of gene editing for Huntington’s disease

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Revisiting CRISPR/Cas-mediated crop improvement: special focus on nutrition

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In vivo continuous evolution of metabolic pathways for chemical production

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Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing

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Efficient prime editing in two-cell mouse embryos using PEmbryo

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Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors

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CRISPR Diagnosis and Therapeutics with Single Base Pair Precision

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CRISPR-based therapeutic genome editing for inherited blood disorders

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Strategies for Developing CRISPR‐Based Gene Editing Methods in Bacteria

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A blueprint for gene function analysis through Base Editing in the model plant Physcomitrium (Physcomitrella) patens

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Editing outside the body: Ex vivo gene-modification for β-hemoglobinopathy cellular therapy

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CRISPR and cardiovascular diseases

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When genome editing goes off-target

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Innovative Precision Gene‐Editing Tools in Personalized Cancer Medicine

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Development of a Self-Restricting CRISPR-Cas9 System to Reduce Off-Target Effects

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Cytosine Base Editor (hA3A-BE3-NG)-Mediated Multiple Gene Editing for Pyramid Breeding in Pigs

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Adenine base editors induce off-target structure variations in mouse embryos and primary human T cells

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CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders

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Genome-wide specificity of dCpf1 cytidine base editors

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Future Perspectives of Prime Editing for the Treatment of Inherited Retinal Diseases

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Mapping and editing of nucleic acid modifications

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BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors

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Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants

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Efficient Generation of Pathogenic A-to-G Mutations in Human Tripronuclear Embryos via ABE-Mediated Base Editing

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Improving the Precision of Base Editing by Bubble Hairpin Single Guide RNA

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Correction of human nonsense mutation via adenine base editing for Duchenne muscular dystrophy treatment in mouse

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Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

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Cytosine base editors go off-target

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Spotting off-targets from gene editing

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Expanding the base editing scope in rice by using Cas9 variants

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