Single-cell transcriptional diversity is a hallmark of developmental potential

Cited by (998)

Items 101–200 of 998

1. Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution
   Xin Li, Shuang Zhao, Xiaohui Bian, Lining Zhang, Lixia Lu, Shiyao Pei, Liang Dong, Wensheng Shi, Lingjuan Huang, Xiyuan Zhang et al. · 2022 · Theranostics
2. Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response
   Xiangdong Cheng, Enyu Dai, Jibo Wu, Natasha Mahealani Flores, Yanshuo Chu, Ruiping Wang, Minghao Dang, Zhiyuan Xu, Guangchun Han, Yunhe Liu et al. · 2024 · Gastroenterology
3. Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
   Chen Guang Yang, Haigang Geng, Xupeng Yang, Shuyi Ji, Zhicheng Liu, Hao Feng, Qian Li, Tangansu Zhang, Si‐Si Zhang, Xuhui Ma et al. · 2024 · Cancer Cell
4. Single-cell transcriptomes reveal spatiotemporal heat stress response in maize roots
   Ting Wang, Fanhua Wang, Shuhan Deng, Kailai Wang, Dan Feng, Fan Xu, Weijun Guo, Jia Yu, Yue Wu, Hada Wuriyanghan et al. · 2025 · Nature Communications
5. SUV39H1 Ablation Enhances Long-term CAR T Function in Solid Tumors
   López-Cobo, Sheila, Fuentealba, Jaime R., Gueguen, Paul, Bonté, Pierre-Emmanuel, Tsalkitzi, Kyriaki, Chacón, Irena, Glauzy, Salomé, Bohineust, Armelle, Biquand, Ariane, Silva, Lisseth et al. · 2024 · Cancer Discovery
6. Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart
   Julia Hesse, Christoph Owenier, Tobias Lautwein, Ria Zalfen, Jonas F Weber, Zhaoping Ding, Christina Alter, Alexander Lang, Maria Grandoch, Norbert Gerdes et al. · 2021 · eLife
7. Decoder-seq enhances mRNA capture efficiency in spatial RNA sequencing
   Cao, Jiao, Zheng, Zhong, Sun, Di, Chen, Xin, Cheng, Rui, Lv, Tianpeng, An, Yu, Zheng, Junhua, Song, Jia, Wu, Lingling et al. · 2024 · Nature Biotechnology
8. A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer
   Acha-Sagredo, Amelia, Andrei, Pietro, Clayton, Kalum, Taggart, Emma, Antoniotti, Carlotta, Woodman, Chloé A., Afrache, Hassnae, Fourny, Constance, Armero, Maria, Moinudeen, Hafsa Kaja et al. · 2025 · Cancer Cell
9. Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies
   Cherry, Christopher, Andorko, James I., Krishnan, Kavita, Mejías, Joscelyn C., Nguyen, Helen Hieu, Stivers, Katlin B., Gray-Gaillard, Elise F., Ruta, Anna, Han, Jin, Hamada, Naomi et al. · 2023 · GeroScience
10. A single-cell multi-omics atlas of rice
    Xiangyu Wang, Huanwei Huang, Sanjie Jiang, Jingmin Kang, Dongwei Li, Kailai Wang, Shang Bo Xie, Tong Cheng, Chaofan Liu, Guihua Hu et al. · 2025 · Nature
11. Transcriptome Analysis Revealed the Symbiosis Niche of 3D Scaffolds to Accelerate Bone Defect Healing
    Ce Ji, Minglong Qiu, Huitong Ruan, Cuidi Li, Liang Cheng, Juan Wang, Changwei Li, Qi Jin, Wenguo Cui, Lianfu Deng · 2022 · Advanced Science
12. Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis
    Jing Zhao, Louis Faure, Igor I. Adameyko, Paul Thomas Sharpe · 2020 · Stem Cells
13. Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells
    Chen Liu, Yandong Gong, Han Zhang, Hua Qian Yang, Yang Zeng, Zhilei Bian, Qian Xin, Zhijie Bai, Man Zhang, Jian He et al. · 2021 · Cell Research
14. Single‐Cell Landscape Highlights Heterogenous Microenvironment, Novel Immune Reaction Patterns, Potential Biomarkers and Unique Therapeutic Strategies of Cervical Squamous Carcinoma, Human Papillomavirus‐Associated (HPVA) and Non‐HPVA Adenocarcinoma
    Junjun Qiu, Xinyu Qu, Yumeng Wang, Chenyan Guo, Bin Lv, Qian Jiang, Wentao Su, Li Wang, Keqin Hua · 2023 · Advanced Science
15. Zn‐DHM Nanozymes Enhance Muscle Regeneration Through ROS Scavenging and Macrophage Polarization in Volumetric Muscle Loss Revealed by Single‐Cell Profiling
    Xinting Feng, Zhiwen Luo, Wei Zhang, Renwen Wan, Yisheng Chen, Fangqi Li, Yanwei He, Zhiheng Lin, James Hoi Po Hui, João Conde et al. · 2025 · Advanced Functional Materials
16. PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes
    Wang, Kun, Hou, Liangzhen, Wang, Xin, Zhai, Xiangwei, Lu, Zhaolian, Zi, Zhike, Zhai, Weiwei, He, Xionglei, Curtis, Christina, Zhou, Da et al. · 2024 · Nature Biotechnology
17. HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis
    Xiang Peng, Bin Sun, Chaohui Tang, Chengyu Shi, Xianwei Xie, Xueyu Wang, Dingsheng Jiang, Shuo Li, Ying Jia, Huifang Tang et al. · 2024 · Developmental Cell
18. Capybara: A computational tool to measure cell identity and fate transitions
    Wenjun Kong, Yuheng C. Fu, Emily M. Holloway, Görkem Garipler, Xue Yang, Esteban O. Mazzoni, Samantha A. Morris · 2022 · Cell stem cell
19. Characterization of Diabetic and Non-Diabetic Foot Ulcers Using Single-Cell RNA-Sequencing
    Michael Januszyk, Kellen Chen, Dominic Henn, Deshka S. Foster, Mimi Rosealie Borrelli, Clark Andrew Bonham, Dharshan Sivaraj, Dhananjay A. Wagh, Michael Thornton Longaker, Derrick C. Wan et al. · 2020 · Micromachines
20. Single-cell genomics in AML: extending the frontiers of AML research
    Asiri Ediriwickrema, Andrew J. Gentles, Ravindra Majeti · 2022 · Blood
21. Stomach encyclopedia: Combined single-cell and spatial transcriptomics reveal cell diversity and homeostatic regulation of human stomach
    Ayumu Tsubosaka, Daisuke Komura, Miwako Kakiuchi, Hiroto Katoh, Takumi Onoyama, Asami Yamamoto, Hiroyuki Abé, Yasuyuki Seto, Tetsuo Ushiku, Shumpei Ishikawa · 2023 · Cell Reports
22. Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches
    Xiongfeng Chen, Zhuan Zhou, Luyu Xie, Kailiang Qiao, Yiyue Jia, Si Liu, Zeynep Yazgan, Francesca Rossi, Yang Liu, Bo Zhang et al. · 2025 · Cancer Cell
23. Single‐cell RNA ‐seq dissecting heterogeneity of tumor cells and comprehensive dynamics in tumor microenvironment during lymph nodes metastasis in gastric cancer
    Yan Qian, Ertao Zhai, Sile Chen, Yinan Liu, Yan Ma, Junting Chen, Jianqiu Liu, Changjiang Qin, Qin Cao, Jianhui Chen et al. · 2022 · International Journal of Cancer
24. Scikit-Dimension: A Python Package for Intrinsic Dimension Estimation
    Jonathan Bac, Evgeny M. Mirkes, Alexander N. Gorban, Ivan Tyukin, Andrei Y. Zinovyev · 2021 · Figshare
25. Single‐Cell Sequencing Methodologies: From Transcriptome to Multi‐Dimensional Measurement
    Yingwen Chen, Jia Tao Song, Qingyu Ruan, Xi Zeng, Lingling Wu, Linfeng Cai, Xuanqun Wang, Chaoyong James Yang · 2021 · Small Methods
26. A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes
    Grancharova, Tanya, Gerbin, Kaytlyn A., Rosenberg, Alexander B., Roco, Charles M., Arakaki, Joy E., DeLizo, Colette M., Dinh, Stephanie Q., Donovan-Maiye, Rory M., Hirano, Matthew, Nelson, Angelique M. et al. · 2021 · Scientific Reports
27. Signature-scoring methods developed for bulk samples are not adequate for cancer single-cell RNA sequencing data
    Nighat Noureen, Zhenqing Ye, Yidong Chen, Xiaojing Wang, Siyuan Zheng · 2022 · eLife
28. Early emergence of T central memory precursors programs clonal dominance during chronic viral infection
    Simon A. Grassmann, Lorenz Mihatsch, Jonas Mir, Atefeh Kazeroonian, Roza Rahimi, Sophie Flommersfeld, Kilian Schober, Inge Hensel, Justin Leube, Ludwig O. Pachmayr et al. · 2020 · Nature Immunology
29. Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation
    Ying Zhang, Pourya Naderi Yeganeh, Haiwei Zhang, Simon Yuan Wang, Zhouyihan Li, Bowen Gu, Dian-Jang Lee, Zhibin Zhang, Athanasios Ploumakis, Ming Shi et al. · 2024 · Nature Immunology
30. Reconciling Non-Genetic Plasticity with Somatic Evolution in Cancer
    Sui Huang · 2021 · Trends in cancer
31. Single-cell analysis of cell identity in the Arabidopsis root apical meristem: insights and opportunities
    Rachel Shahan, Trevor M. Nolan, Philip N. Benfey · 2021 · Journal of Experimental Botany
32. Clinical and biological heterogeneities in triple-negative breast cancer reveals a non-negligible role of HER2-low
    Xie Hu, Ping Yang, Songhao Chen, Gang Wei, Lijuan Yuan, Zhenyu Yang, Li Gong, Li He, Lin Yang, Shujia Peng et al. · 2023 · Breast Cancer Research
33. CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing
    Jinhao Zhang, Gaoge Peng, Hao Chi, Jinyan Yang, Xixi Xie, Guobin Song, Lisa Jia Tran, Zhijia Xia, Gang Tian · 2023 · BMC Oral Health
34. Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease
    Jia Li, Alan J. Simmons, Caroline V. Hawkins, Sophie Chiron, Marisol A Ramirez-Solano, Naila Tasneem, Harsimran Kaur, Yanwen Xu, Frank L. Revetta, Paige N. Vega et al. · 2024 · Nature Communications
35. Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes
    Gerbin, Kaytlyn A., Grancharova, Tanya, Donovan-Maiye, Rory M., Hendershott, Melissa C., Anderson, Helen G., Brown, Jackson M., Chen, Jianxu, Dinh, Stephanie Q., Gehring, Jamie L., Johnson, Gregory R. et al. · 2021 · Cell Systems
36. Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development
    Xin Zhou, Yufeng Lu, Fangqi Zhao, Ji Dong, Wenji Ma, Suijuan Zhong, Mengdi Wang, Bosong Wang, Yuqing Zhao, Yingchao Shi et al. · 2021 · Cell stem cell
37. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis
    David Lara‐Astiaso, Ainhoa Goñi‐Salaverri, Julen Mendieta-Esteban, Nisha Narayan, Cynthia del Valle, Torsten Groß, George Giotopoulos, Tumas Beinortas, Mar Navarro-Alonso, Laura Pilar Aguado‐Alvaro et al. · 2023 · Nature Genetics
38. Decoding the gene regulatory network of endosperm differentiation in maize
    Yue Yuan, Qiang Huo, Ziru Zhang, Qun Wang, Juanxia Wang, Shuaikang Chang, Peng Cai, K. Song, David W. Galbraith, Weixiao Zhang et al. · 2024 · Nature Communications
39. Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis
    Farshad Farshidfar, Kahn Rhrissorrakrai, Chaya Levovitz, Cong Peng, James Knight, Antonella Bacchiocchi, Juan Su, Mingzhu Yin, Mario Sznol, Stephan Ariyan et al. · 2022 · Nature Communications
40. Single cell clonotypic and transcriptional evolution of multiple myeloma precursor disease
    Dang, Minghao, Han, Guangchun, Lee, Hans C., Patel, Krina K., Becnel, Melody R., Wang, Ruiping, Thomas, Sheeba K., Hao, Dapeng, Chu, Yanshuo, Weber, Donna M. et al. · 2023 · Cancer Cell
41. Multiomics profiling reveals the benefits of gamma-delta (γδ) T lymphocytes for improving the tumor microenvironment, immunotherapy efficacy and prognosis in cervical cancer
    Junyi Li, Yuanjie Cao, Yan‐Cheng Liu, Yu Lu, Zhen Zhang, Xiaofeng Wang, Hui Bai, Yuhan Zhang, Shaochuan Liu, Miaomiao Gao et al. · 2024 · Journal for ImmunoTherapy of Cancer
42. Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation
    Mathijs P. Verhagen, Rosalie Joosten, Mark Schmitt, Niko Välimäki, Andrea Sacchetti, Kristiina Rajamäki, Jiahn Choi, Paola Procopio, Sara Neves Silva, Berdine van der Steen et al. · 2024 · Nature Genetics
43. Exploring cellular diversity in lung adenocarcinoma epithelium: Advancing prognostic methods and immunotherapeutic strategies
    Lianmin Zhang, Yanan Cui, Jie Mei, Zhenfa Zhang, Pengpeng Zhang · 2024 · Cell Proliferation
44. Cranioencephalic functional lymphoid units in glioblastoma
    Celia Dobersalske, Laurèl Rauschenbach, Yichao Hua, Christoph Berliner, Anita Steinbach, Anika Grüneboom, Konstantinos D. Kokkaliaris, Dieter Henrik Heiland, Pia Berger, Sarah Langer et al. · 2024 · Nature Medicine
45. GepLiver: an integrative liver expression atlas spanning developmental stages and liver disease phases
    Ziteng Li, Hena Zhang, Qin Li, Wanjing Feng, Xiya Jia, Runye Zhou, Yi Huang, Yan Li, Zhixiang Hu, Xichun Hu et al. · 2023 · Scientific Data
46. Single-cell RNA sequencing reveals that MYBL2 in malignant epithelial cells is involved in the development and progression of ovarian cancer
    Wenwen Shao, Zhiheng Lin, Zhikai Xiahou, Fu Zhao, Jue Xu, Xinqi Liu, Pingping Cai · 2024 · Frontiers in Immunology
47. Cascade diversification directs generation of neuronal diversity in the hypothalamus
    Yu-Hong Zhang, Mingrui Xu, Xiang Shi, Xuelian Sun, Wenhui Mu, Haoda Wu, Jingjing Wang, Si Li, Pengfei Su, Ling Gong et al. · 2021 · Cell stem cell
48. Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis
    Kohei Saeki, Gregory Chang, Noriko Kanaya, Xiwei Wu, Jinhui Wang, Lauren Bernal, Desiree Ha, Susan L. Neuhausen, Shiuan Chen · 2021 · Communications Biology
49. Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma
    Julia Frede, Praveen Anand, Noori Sotudeh, Ricardo A. Pinto, Monica S. Nair, Hannah Stuart, Andrew Jenho Yee, Tushara Vijaykumar, Johannes Moritz Waldschmidt, Sayalee V. Potdar et al. · 2021 · Nature Cell Biology
50. Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level
    Kannan, Suraj, Farid, Michael, Lin, Brian L., Miyamoto, Matthew, Kwon, Chulan · 2021 · PLOS Computational Biology
51. Applications of Single-Cell Omics in Tumor Immunology
    Junwei Liu, Saisi Qu, Tongtong Zhang, Yufei Gao, Hongyu Shi, Kaichen Song, Wei Chen, Weiwei Yin · 2021 · Frontiers in Immunology
52. Regulatory mechanism of miR-20a-5p expression in Cancer
    Wei Huang, Xiaoyue Wu, Shuaixi Xiang, Mingxin Qiao, Xiao Bo Cen, Xuefeng Pan, Xinqi Huang, Zhihe Zhao · 2022 · Cell Death Discovery
53. Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4
    Gaetano D’Amato, Ragini Phansalkar, Jeffrey A. Naftaly, Xiaochen Fan, Zhainib Adel Amir, Pamela E. Rios Coronado, Dale O. Cowley, Kelsey E. Quinn, Bikram Sharma, Kathleen M. Caron et al. · 2022 · Developmental Cell
54. Decoding transcriptional identity in developing human sensory neurons and organoid modeling
    Lu Tian, Mengdi Wang, Wei Zhou, Qi Ni, Yuanlei Yue, Wei Wang, Yingchao Shi, Zeyuan Liu, Changlin Li, Bei Hong et al. · 2024 · Cell
55. Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution
    Zhisheng Wu, Yiheng Wang, Weiwei Chen, Hua Sun, Xiaoyan Chen, Xiaobo Li, Zeshuai Wang, Weizheng Liang, Shuang-Yin Wang, Xuemei Luan et al. · 2025 · Cell
56. Mammary epithelial cells have lineage-rooted metabolic identities
    Mathepan Jeya Mahendralingam, Hye‐Yeon Kim, Curtis W. McCloskey, Kazeera Aliar, Alison E. Casey, Pirashaanthy Tharmapalan, Davide Pellacani, Vladimir Ignatchenko, Mar García-Valero, Luís Palomero et al. · 2021 · Nature Metabolism
57. The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis
    Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto et al. · 2023 · Cell Reports
58. Directionality of developing skeletal muscles is set by mechanical forces
    Kazunori Sunadome, Alek G. Erickson, Delf Kah, Ben Fabry, Csaba Ádori, Polina Kameneva, Louis Faure, Shigeaki Kanatani, Markéta Kaucká, Ivar Dehnisch Ellström et al. · 2023 · Nature Communications
59. Single-cell RNA sequencing unveils Lrg1's role in cerebral ischemia‒reperfusion injury by modulating various cells
    Zhaohui Ruan, Guosheng Cao, Yisong Qian, Longsheng Fu, Jinfang Hu, Tiantian Xu, Yaoqi Wu, Yanni Lv · 2023 · Journal of Neuroinflammation
60. A single cell RNA sequencing resource for early sea urchin development
    Stephany Foster, Nathalie Oulhen, Gary M. Wessel · 2020 · Development
61. Dach1 Extends Artery Networks and Protects Against Cardiac Injury
    Brian C. Raftrey, Ian M. Williams, Pamela E. Rios Coronado, Xiaochen Fan, Andrew H. Chang, Mingming Zhao, Robert Roth, Emily Trimm, Raquel Racelis, Gaetano D’Amato et al. · 2021 · Circulation Research
62. RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification
    Naohiro Tachibana, Ryota Chijimatsu, Hiroyuki Okada, Takeshi Oichi, Yuki Taniguchi, Yuji Maenohara, Junya Miyahara, Hisatoshi Ishikura, Yasuhide Iwanaga, Yusuke Arino et al. · 2022 · Science Advances
63. Dental niche cells directly contribute to tooth reconstitution and morphogenesis
    Hong Hu, Yufeng Duan, Kun Wang, Huancheng Fu, Yuansong Liao, Tianshu Wang, Ziwei Zhang, Fanchen Kang, Baiquan Zhang, Haiying Zhang et al. · 2022 · Cell Reports
64. Single-nucleus sequencing deciphers developmental trajectories in rice pistils
    Chengxiang Li, Songyao Zhang, Xingying Yan, Peng Cheng, Hao Qiang Yu · 2023 · Developmental Cell
65. scRNA-seq of colorectal cancer shows regional immune atlas with the function of CD20+ B cells
    Linlin Ji, Gongbo Fu, Mengxi Huang, Xiaoming Kao, Jialong Zhu, Zhe Dai, Yitian Chen, Huiyu Li, Jie Zhou, Xiaoyuan Chu et al. · 2024 · Cancer Letters
66. Bulk and single-cell characterisation of the immune heterogeneity of atherosclerosis identifies novel targets for immunotherapy
    Jie Xiong, Zhaoyue Li, Hao Tang, Yuchen Duan, Xiaofang Ban, Ke Xu, Yutong Guo, Yingfeng Tu · 2023 · BMC Biology
67. Uncovering the potential role of oxidative stress in the development of periodontitis and establishing a stable diagnostic model via combining single-cell and machine learning analysis
    Guobin Song, Gaoge Peng, Jinhao Zhang, Binyu Song, Jinyan Yang, Xixi Xie, Siqi Gou, Jing Zhang, Guanhu Yang, Hao Chi et al. · 2023 · Frontiers in Immunology
68. An iron rheostat controls hematopoietic stem cell fate
    Yun-Ruei Kao, Jiahao Chen, Rajni Kumari, Anita Kar Yun Ng, Aliona Zintiridou, Madhuri Tatiparthy, Yuhong Ma, Maria M. Aivalioti, Deeposree Moulik, Sriram Sundaravel et al. · 2024 · Cell stem cell
69. Single-cell analysis of innate spinal cord regeneration identifies intersecting modes of neuronal repair
    Vishnu Muraleedharan Saraswathy, Lili Zhou, Mayssa H. Mokalled · 2024 · Nature Communications
70. A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis
    Rong Li, M. Colombo, Guanlin Wang, Antonio Rodriguez-Romera, Camélia Benlabiod, Natalie J. Jooss, Jennifer O’Sullivan, Charlotte K. Brierley, Sally‐Ann Clark, Juan M. Pérez‐Sáez et al. · 2024 · Science Translational Medicine
71. Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease
    Ahmed Disouky, Mark A. Sanborn, K.R. Sabitha, MOSTAFA MOSTAFA, Ivan Alejandro Ayala, David A. A Bennett, Yisha Lu, Yi Fu Zhou, Christopher Dirk Keene, Sandra Weıntraub et al. · 2026 · Nature
72. Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium
    Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shogo Nakayama, Takeru Oka, Osamu Sugahara, Daisuke Koga, Shoichiro Takeishi, Hirokazu Nakatsumi, Naoki Hosen et al. · 2022 · Nature Communications
73. Single-cell profiling reveals kidney CD163+ dendritic cell participation in human lupus nephritis
    Wei Chen, Bei Jin, Cheng Cheng, Huajing Peng, Xinxin Zhang, Weiping Tan, Ruihan Tang, Xingji Lian, Hui Diao, Ning Luo et al. · 2024 · Annals of the Rheumatic Diseases
74. Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
    Lin Fan, Junwei Liu, Wei Hu, Zexin Chen, Jie Lan, Tongtong Zhang, Yang Zhang, Xianpeng Wu, Zhiwei Zhong, Danyang Zhang et al. · 2024 · Cell Research
75. Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing
    Dominic Henn, Dehua Zhao, Dharshan Sivaraj, Artem A. Trotsyuk, Clark Andrew Bonham, Katharina S. Fischer, Tim Kehl, Tobias Fehlmann, Autumn H. Greco, Hudson C. Kussie et al. · 2023 · Nature Communications
76. Integrated analysis of single-cell and bulk transcriptomics develops a robust neuroendocrine cell-intrinsic signature to predict prostate cancer progression
    Tingting Zhang, Faming Zhao, Yahang Lin, Mingsheng Liu, Hongqing Zhou, Fengzhen Cui, Yang Jin, Liang Chen, Xia Sheng · 2024 · Theranostics
77. Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer
    Zhiheng Lin, Fengxin Wang, Renwu Yin, Shengnan Li, Yuquan Bai, Baofang Zhang, Chen-Lin Sui, Hengjie Cao, Dune Su, Lianwei Xu et al. · 2025 · Frontiers in Immunology
78. Evolutionary fingerprints of epithelial-to-mesenchymal transition
    Luigi Perelli, Li Zhang, Sarah M. Mangiameli, Francesca Giannese, Krishnan K. Mahadevan, Fuduan Peng, Francesca Citron, Hania Khan, Courtney N. Le, Enrico Gurreri et al. · 2025 · Nature
79. Single-Cell RNA Sequencing Reveals the Difference in Human Normal and Degenerative Nucleus Pulposus Tissue Profiles and Cellular Interactions
    Zhencong Li, Dongping Ye, Libing Dai, Yude Xu, Hao Wu, Wei Feng Luo, Yiming Liu, Xiguan Yao, Peigeng Wang, Haixiong Miao et al. · 2022 · Frontiers in Cell and Developmental Biology
80. Towards AI-driven longevity research: An overview
    Nicola Marino, Guido Putignano, Simone Cappilli, Emmanuele Chersoni, Antonella Santuccione Chadha, Giuliana Calabrese, Evelyne Yehudit Bischof, Quentin Vanhaelen, Alex A. Zhavoronkov, Bryan Scarano et al. · 2023 · Frontiers in Aging
81. Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration
    Phong D. Nguyen, Iris Gooijers, Giulia Campostrini, Arie O. Verkerk, Hessel Honkoop, Mara Bouwman, Dennis E. M. de Bakker, Tim Koopmans, Aryan Vink, Gerda E. M. Lamers et al. · 2023 · Science
82. A single-cell transcriptome atlas reveals the trajectory of early cell fate transition during callus induction in Arabidopsis
    Ruilian Yin, Ruiying Chen, Keke Xia, Xun Xu · 2024 · Plant Communications
83. Distinct adipose progenitor cells emerging with age drive active adipogenesis
    Guan Wang, Gaoyan Li, Anying Song, Yutian Zhao, Jiayu Yu, Yifan Wang, Wenting Dai, Martha C. Salas, Hanjun Qin, Leonard J. Medrano et al. · 2025 · Science
84. Diagnostic classification of childhood cancer using multiscale transcriptomics
    Federico Comitani, Joshua O. Nash, Sarah Cohen‐Gogo, Astra I. Chang, Timmy T. Wen, Anant Maheshwari, Bipasha Goyal, Earvin S. Tio, Kevin Tabatabaei, Chelsea Mayoh et al. · 2023 · Nature Medicine
85. Lost in space: what single-cell RNA sequencing cannot tell you
    Kelvin Adema, Michael A. Schon, Michael D. Nodine, Wouter Kohlen · 2024 · Trends in Plant Science
86. Macrophage and fibroblast trajectory inference and crosstalk analysis during myocardial infarction using integrated single-cell transcriptomic datasets
    Da Ke, Mingzhen Cao, Jian Ni, Yuan Yuan, Jiang-yang Deng, Si Chen, Xiujun Dai, Heng Zhou · 2024 · Journal of Translational Medicine
87. A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade
    Weiyuan Li, Lu Pan, Weifeng Hong, Florent Ginhoux, Xuan Zhang, Chunjie Xiao, Xuexin Li · 2024 · Nature Communications
88. Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer
    Lisa Veghini, Davide Pasini, Rui Fang, Pietro Delfino, Dea Filippini, Christian Neander, Caterina Vicentini, Elena Fiorini, Francesca Lupo, Sabrina L. D’Agosto et al. · 2024 · Nature Communications
89. THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1
    Julie Giraud, Domitille Chalopin, Eloïse Ramel, Thomas Boyer, Atika Zouine, Marie‐Alix Derieppe, Nicolas Larmonier, Olivier Adotévi, Brigitte Le Bail, Jean‐Frédéric Blanc et al. · 2024 · Cell Reports
90. Tracking single-cell evolution using clock-like chromatin accessibility loci
    Yu Xiao, Wan Jin, Lingao Ju, Jie Fu, Gang Wang, Mengxue Yu, Fangjin Chen, Kaiyu Qian, Xinghuan Wang, Yi Zhang · 2024 · Nature Biotechnology
91. De novo generation of macrophage from placenta-derived hemogenic endothelium
    Guixian Liang, Chunyu Zhou, Xiangxiang Jiang, Yifan Zhang, Baofeng Huang, Suwei Gao, Zhixin Kang, Dongyuan Ma, Fengchao Wang, Berthold Göttgens et al. · 2021 · Developmental Cell
92. Exercise improves choroid plexus epithelial cells metabolism to prevent glial cell-associated neurodegeneration
    Yisheng Chen, Zhiwen Luo, Yaying Sun, Fangqi Li, Zhihua Han, Beijie Qi, Jinrong Lin, Wei-Wei Lin, Mengxuan Yao, Xueran Kang et al. · 2022 · Frontiers in Pharmacology
93. High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival
    Erik P. Storrs, Prathamesh Chati, Abul Usmani, Ian H. Sloan, Bradley Aaron Krasnick, Ramandeep K. Babbra, Peter K. W. Harris, Chloe M. Sachs, Faridi Qaium, Deyali Chatterjee et al. · 2023 · npj Precision Oncology
94. Hypoxia-Induced Senescent Fibroblasts Secrete IGF1 to Promote Cancer Stemness in Esophageal Squamous Cell Carcinoma
    Zhengjie Ou, LIANG BO ZHU, Xinjie Chen, Tianyuan Liu, Guoyu Cheng, Rucheng Liu, Shaosen Zhang, Wen Tan, Dongxin Lin, Chen Hsuan Wu · 2024 · Cancer Research
95. Cell populations in neonatal rat peripheral nerves identified by single‐cell transcriptomics
    Ruirui Zhang, Sailing Chen, Xinghui Wang, Xiaosong Gu, Sheng Yi · 2020 · Glia
96. Optimal transport analysis reveals trajectories in steady-state systems
    Stephen Zhang, Anton Afanassiev, Laura Greenstreet, Tetsuya Matsumoto, Geoffrey R. Schiebinger · 2021 · PLoS Computational Biology
97. scRNA-seq revealed high stemness epithelial malignant cell clusters and prognostic models of lung adenocarcinoma
    GuoYong Lin, ZhiSen Gao, Shun Wu, JianPing Zheng, XiangQiong Guo, Xiaohong Zheng, RunNan Chen · 2024 · Scientific Reports
98. Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch
    Weifeng Lin, Xiaohui Jia, Xiaofeng Shi, Qiuya He, Panyu Zhang, Xianglei Zhang, Liping Zhang, Mingqi Wu, Tengfei Ren, Yufei Liu et al. · 2025 · Science
99. Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration
    Li Ping Tang, Li Ming Zhai, Jiming Li, Yue Gao, Qiu Li Ma, Rui Li, Qing Fei Liu, Wen Jie Zhang, Wang Jinsong Yao, Bangbang Mu et al. · 2025 · Cell
100. The Combination of R848 with Sorafenib Enhances Antitumor Effects by Reprogramming the Tumor Immune Microenvironment and Facilitating Vascular Normalization in Hepatocellular Carcinoma
     Yuchao He, Linlin Zhan, Jian Shi, Man‐Yu Xiao, Ran Zuo, Chengmeng Wang, Zhiyong Liu, Wenchen Gong, Liwei Chen, Yi Luo et al. · 2023 · Advanced Science