The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Identification of a choroid plexus vascular barrier closing during intestinal inflammation
Abstract
Locking down access to the brain: Inflammatory bowel disease is best known for intestinal symptoms but can also cause a variety of extraintestinal manifestations in other organs. It can also be associated with cognitive and psychiatric effects, including anxiety and depression. Using mouse models of intestinal inflammation, Carloni et al . uncovered a potential pathogenic link between these aspects of inflammatory bowel disease. The inflammatory process causes the gut vascular barrier to become more permeable, resulting in the spread of inflammation beyond the intestine, while the vascular barrier in the choroid plexus shuts down, helping protect the brain from inflammation but also potentially impairing communication between organs and impairing some brain functions. —YN
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Transforming the understanding of brain immunity
Castellani, G., Croese, T., Peralta Ramos, J. M., & Schwartz, M. (2023) · Science · doi:10.1126/science.abo7649 · Cited by 386
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Metadata
- Authors
- Carloni, S., Bertocchi, A., Mancinelli, S., Bellini, M., Erreni, M., Borreca, A., Braga, D., Giugliano, S., Mozzarelli, A. M., Manganaro, D., Fernandez Perez, D., Colombo, F., Di Sabatino, A., Pasini, D., Penna, G., Matteoli, M., Lodato, S., & Rescigno, M.
- Venue
- Science
- Published
- 2021-10-22
- Volume
- 374
- Issue
- 6566
- Pages
- 439-448
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W3205139696
- Cited by
- 268
- References
- 74
- FWCI
- 14.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- Carloni, S., Bertocchi, A., Mancinelli, S., Bellini, M., Erreni, M., Borreca, A., Braga, D., Giugliano, S., Mozzarelli, A. M., Manganaro, D., Fernandez Perez, D., Colombo, F., Di Sabatino, A., Pasini, D., Penna, G., Matteoli, M., Lodato, S., & Rescigno, M. (2021). Identification of a choroid plexus vascular barrier closing during intestinal inflammation. Science. https://doi.org/10.1126/science.abc6108
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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