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Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression
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Common changes in signaling pathway–associated gene expression may explain why chronic pain or stress can lead to depression.
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“LAMB2 is involved in neuropathic pain and influencing gene expression changes in brain pathways implicated in depression.36”
From Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions (2021) · cites this paper as [36]
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Cites
From inflammation to sickness and depression: when the immune system subjugates the brain
Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395
Causal analysis approaches in Ingenuity Pathway Analysis
Krämer, A., Green, J., Pollard, J., & Tugendreich, S. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btt703 · Cited by 5,724
Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875
Cellular and Molecular Mechanisms of Pain
Basbaum, A. I., Bautista, D. M., Scherrer, G., & Julius, D. (2009) · Cell · doi:10.1016/j.cell.2009.09.028 · Cited by 4,344
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
Greenberg, M. E., & Ziff, E. B. (1984) · Nature · doi:10.1038/311433a0 · Cited by 2,992
Goll, D. E., Thompson, V. F., Li, H., WEI, W., & Cong, J. (2003) · Physiological Reviews · doi:10.1152/physrev.00029.2002 · Cited by 2,899
Willner, P., Towell, A., Sampson, D., Sophokleous, S., & Muscat, R. (1987) · Psychopharmacology · doi:10.1007/bf00187257 · Cited by 1,993
The brain reward circuitry in mood disorders
Russo, S. J., & Nestler, E. J. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3381 · Cited by 1,870
Willner, P. (1997) · Psychopharmacology · doi:10.1007/s002130050456 · Cited by 1,832
Research works printed but not linked: 1
- Committee on Advancing Pain Research and Education Relieving Pain in America: A Blueprint for Transforming Prevention Care Education and Research (The National Academies Press 2011).
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Levey, D. F., Stein, M. B., Wendt, F. R., Pathak, G. A., Zhou, H., Aslan, M., Quaden, R., Harrington, K. M., Nuñez, Y. Z., Overstreet, C., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00860-2 · Cited by 422
Zhou, X., Wahane, S., Friedl, M.-S., Kluge, M., Friedel, C. C., Avrampou, K., Zachariou, V., Guo, L., Zhang, B., He, X., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0597-7 · Cited by 275
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Serafini, R. A., Pryce, K. D., & Zachariou, V. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.10.018 · Cited by 237
Self-citationThe Role of the Locus Coeruleus in Pain and Associated Stress-Related Disorders
Suárez‐Pereira, I., Llorca-Torralba, M., Bravo, L., Camarena-Delgado, C., Soriano‐Mas, C., & Berrocoso, E. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.11.023 · Cited by 181
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Kremer, M., Becker, L. J., Barrot, M., & Yalçın, İ. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14686 · Cited by 176
The molecular neurobiology of chronic pain–induced depression
Humo, M., Lu, H., & Yalçın, İ. (2019) · Cell and Tissue Research · doi:10.1007/s00441-019-03003-z · Cited by 167
Guida, F., Gregorio, D. D., Palazzo, E., Ricciardi, F., Boccella, S., Belardo, C., Iannotta, M., Infantino, R., Formato, F., Marabese, I., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093396 · Cited by 130
Brain Microglial Activation in Chronic Pain-Associated Affective Disorder
Barcelon, E. E., Cho, W.-H., Jun, S. B., & Lee, S. J. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00213 · Cited by 118
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Coussens, N. P., Sittampalam, G. S., Jonson, S. G., Hall, M. D., Gorby, H. E., Tamiz, A. P., McManus, O. B., Felder, C. C., & Rasmussen, K. (2019) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.119.259408 · Cited by 112
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Song, J., & Kim, Y. (2021) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13622 · Cited by 112
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Niculescu, A. B., Le-Niculescu, H., Levey, D. F., Roseberry, K., Soe, K. C., Rogers, J., Khan, F., Jones, T., Judd, S., McCormick, M. A., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0345-5 · Cited by 99
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Torta, R., Ieraci, V., & Zizzi, F. (2017) · Pain and Therapy · doi:10.1007/s40122-017-0088-z · Cited by 86
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Meng, W., Adams, M. J., Reel, P. S., Rajendrakumar, A. L., Huang, Y. S., Deary, I. J., Palmer, C. N. A., McIntosh, A. M., & Smith, B. H. (2019) · European Journal of Human Genetics · doi:10.1038/s41431-019-0530-2 · Cited by 84
Bhattacherjee, A., Zhang, C., Watson, B. R., Djekidel, M. N., Moffitt, J. R., & Zhang, Y. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01455-9 · Cited by 71
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Zhu, X., Zhou, W., Jin, Y., Tang, H.-D., Cao, P., Mao, Y., Xie, W., Zhang, X., Zhao, F., Luo, M.-H., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.11.003 · Cited by 74
Kimura, L. F., Novaes, L. S., Picolo, G., Munhoz, C. D., Cheung, C. W., & Camarini, R. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15584 · Cited by 70
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Baeza‐Flores, G. D. C., Guzmán‐Priego, C. G., Flores, L. I. P., Murbartián, J., Torres‐López, J. E., & Granados‐Soto, V. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.558474 · Cited by 65
Wang, X., Jiang, Y., Li, J., Wang, Y., Tian, Y., Guo, Q., & Cheng, Z. (2021) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00567 · Cited by 60
Pitzer, C., Porta, C. L., Treede, R., & Tappe‐Theodor, A. (2018) · European Journal of Pain · doi:10.1002/ejp.1303 · Cited by 59
Mo, K., Wu, S., Gu, X., Xiong, M., Cai, W., Atianjoh, F. E., Jobe, E. E., Zhao, X., Tu, W., & Tao, Y. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0880-18.2018 · Cited by 59
Pagé, M. G., Fortier, M., Ware, M. A., & Choinière, M. (2018) · Journal of Pain Research · doi:10.2147/jpr.s149262 · Cited by 58
Looking beyond the intervertebral disc: the need for behavioral assays in models of discogenic pain
Mosley, G. E., Evashwick‐Rogler, T. W., Lai, A., & Iatridis, J. C. (2017) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13429 · Cited by 52
Kong, Q., Li, T., Reddy, S., Hodges, S., & Kong, J. (2023) · Neurotherapeutics · doi:10.1016/j.neurot.2023.10.007 · Cited by 55
Satyanarayanan, S. K., Shih, Y.-H., Wen, Y., Palani, M., Lin, Y., Su, H., Gałecki, P., & Su, K. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.08.190 · Cited by 51
Pain-Associated Transcriptome Changes in Synovium of Knee Osteoarthritis Patients
Bratus-Neuenschwander, A., Castro-Giner, F., Frank‐Bertoncelj, M., Aluri, S., Fucentese, S. F., Schlapbach, R., & Sprott, H. (2018) · Genes · doi:10.3390/genes9070338 · Cited by 51
Dattilo, V., Amato, R., Perrotti, N., & Gennarelli, M. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00826 · Cited by 49
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Tobin, D. G., Lockwood, M. B., Kimmel, P. L., Dember, L. M., Eneanya, N. D., Jhamb, M., Nolin, T. D., Becker, W. C., & Fischer, M. J. (2021) · Nature Reviews Nephrology · doi:10.1038/s41581-021-00484-6 · Cited by 55
Sun, W., Kou, D., Yu, Z., Yang, S., Jiang, C., Xiong, D., Xiao, L., Deng, Q., Xie, H., & Hao, Y. (2019) · NeuroMolecular Medicine · doi:10.1007/s12017-019-08581-3 · Cited by 48
Mosley, G. E., Wang, M., Nasser, P. R., Lai, A., Charen, D. A., Zhang, B., & Iatridis, J. C. (2020) · Scientific Reports · doi:10.1038/s41598-020-72081-9 · Cited by 50
Mecca, C. M., Chao, D., Yu, G., Feng, Y., Segel, I., Zhang, Z., Rodríguez-García, D., Pawela, C. P., Hillard, C. J., Hogan, Q. H., et al. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.3135-20.2021 · Cited by 47
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Wang, X., Mokhtari, T., Zeng, Y., Yue, L., & Hu, L. (2021) · Neural Plasticity · doi:10.1155/2021/6682275 · Cited by 47
Zhang, X., Feng, C., Pei, L., Zhang, Y.-N., Chen, L., Wei, X., Zhou, J. J., Yong, Y., & Wang, K. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.657507 · Cited by 44
Bibliometric Study of the Comorbidity of Pain and Depression Research
Wang, X., Peng, M., Weng, L., Zheng, Y.-L., Zhang, Z., & Chen, P. (2019) · Neural Plasticity · doi:10.1155/2019/1657498 · Cited by 46
Liang, L., Wei, J., Tian, L., Nagendra, B. V. P., Gao, F., Zhang, J., Xu, L., Wang, H., & Huo, F.-Q. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.11.031 · Cited by 42
Hervé, M., Bergon, A., Guisquet, A. L., Leman, S., Consoloni, J.-L., Fernandez, N., Lefebvre, M., El‐Hage, W., Belzeaux-R, R., Belzung, C., et al. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00248 · Cited by 41
Li, Q., Liu, S., Zhu, X., Mi, W., Mao‐Ying, Q., Wang, J., Yu, J. M., & Wang, Y.-Q. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.05.025 · Cited by 40
Chronic pain impact on rodents’ behavioral repertoire
Cunha, A. M., Pereira-Mendes, J., Almeida, A., Guimarães, M. R., & Leite‐Almeida, H. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.022 · Cited by 38
The paraventricular thalamus input to central amygdala controls depression-related behaviors
Zhao, D., Liu, C., Cui, M., Liu, J., Meng, F., Lian, H., Wang, D., Hu, F., Liu, D., & Li, C. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113744 · Cited by 40
The antiviral alkaloid berberine ameliorates neuropathic pain in rats with peripheral nerve injury
Yang, S., Yu, Z., Sun, W., Jiang, C., Ba, X., Zhou, Q., Xiong, D., Xiao, L., Deng, Q., & Hao, Y. (2018) · Acta Neurologica Belgica · doi:10.1007/s13760-018-1006-9 · Cited by 36
Yang, L., Lu, J., Guo, J., Chen, J., Xiong, F., Wang, X., Chen, L., & Yu, C. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0920-22.2022 · Cited by 37
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Xiong, H.-Y., Wyns, A., Campenhout, J. V., Hendrix, J., Bruyne, E. D., Godderis, L., Schabrun, S. M., Nijs, J., & Polli, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158324 · Cited by 39
Sun, W., Yang, S., Wu, S., Ba, X., Xiong, D., Xiao, L., & Hao, Y. (2022) · Molecular Pain · doi:10.1177/17448069221106167 · Cited by 33
Costa, F. V., Rosemberg, D. B., Rosa, L. V., de Quadros, V. A., de Abreu, M. S., Santos, A. R. S., Sneddon, L. U., & Kalueff, A. V. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210311104408 · Cited by 33
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Nestler, E. J., & Waxman, S. G. (2020) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2020.03.007 · Cited by 33
Dai, W.-P., Huang, S., Luo, Y. M., Cheng, X. R., Xia, P., Yang, M., Zhao, P., Zhang, Y., Lin, W., & Ye, X. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.886916 · Cited by 33
Li, X., Shi, W., Chen, Q., Hao, S., Miao, H., Miao, Z., Xu, F., Bi, G., & Zhuo, M. (2023) · Communications Biology · doi:10.1038/s42003-023-05589-1 · Cited by 30
Jeong, H., Moye, L. S., Southey, B. R., Hernández, Á. G., Dripps, I. J., Romanova, E. V., Rubakhin, S. S., Sweedler, J. V., Pradhan, A. A. A., & Rodriguez‐Zas, S. L. (2018) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2018.00063 · Cited by 30
Zhu, X., Xu, Y., Shen, Z., Zhang, H., Xiao, S., Zhu, Y., Wu, M., Chen, Y., Wu, Z., Xu, Y., et al. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.757628 · Cited by 30
Li, Y., Liu, X., Fu, Q., Fan, W., Shao, X., Fang, J., Liu, J., & Xu, C. (2023) · Stem Cells · doi:10.1093/stmcls/sxad007 · Cited by 31
Gu, P., Pan, Z., Wang, X., Sun, L., Tai, W. L., & Cheung, C. W. (2017) · Pain · doi:10.1097/j.pain.0000000000001125 · Cited by 29
Sakloth, F., Manouras, L., Avrampou, K., Mitsi, V., Serafini, R. A., Pryce, K. D., Cogliani, V., Berton, O., Jarpe, M. B., & Zachariou, V. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05525-9 · Cited by 29
Self-citationGaspari, S., Purushothaman, I., Cogliani, V., Sakloth, F., Neve, R. L., Howland, D., Ring, R. H., Ross, E. M., Shen, L., & Zachariou, V. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1707887115 · Cited by 29
Self-citationDepolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation
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Self-citationBoullon, L., Finn, D. P., & Llorente‐Berzal, A. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2021.673638 · Cited by 28
Țenea-Cojan, Ș.-T., Dinescu, V.-C., Gheorman, V., Dragne, I.-G., Gheorman, V., Forțofoiu, M.-C., Forţofoiu, M., & Dobrinescu, A. (2025) · Life · doi:10.3390/life15020251 · Cited by 29
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Islam, B., Stephenson, J. R., Young, B., Manca, M., Buckley, D. A., Radford, H. E., Zis, P., Johnson, M. I., Finn, D. P., & McHugh, P. (2021) · NeuroMolecular Medicine · doi:10.1007/s12017-021-08694-8 · Cited by 23
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Geva, N., Golan, S., Pinchas, L., & Defrin, R. (2022) · Pain · doi:10.1097/j.pain.0000000000002743 · Cited by 22
Pryce, K. D., Serafini, R. A., Ramakrishnan, A., Nicolais, A., Giosan, I. M., Polizu, C., Torres‐Berrío, A., Vuppala, S., Kronman, H. G., Ruiz, A., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01350-3 · Cited by 22
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Guo, J., Wang, C., Niu, X., Zhou, F. J., Li, H., & Weifang, G. (2019) · Acta Neurologica Belgica · doi:10.1007/s13760-019-01126-2 · Cited by 22
Su, S., Li, M., Wu, D., Cao, J., Ren, X., Tao, Y., & Zang, W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.634810 · Cited by 22
Wu, C.-C., Chang, C.-Y., Tzeng, C., Huang, J.-H., Hung, C.-J., Chen, W., Liao, S., Kuan, Y., & Chen, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137197 · Cited by 21
Himmel, N. J., Sakurai, A., Letcher, J. M., Patel, A. A., Bhattacharjee, S., Benson, M. N., Gray, T. R., Cymbalyuk, G. S., & Cox, D. N. (2023) · eLife · doi:10.7554/elife.76863 · Cited by 21
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Wilson‐Poe, A. R., Wiese, B. M., Kibaly, C., Lueptow, L. M., Garcia, J. J., Anand, P., Cahill, C. M., & Morón, J. A. (2021) · PAIN Reports · doi:10.1097/pr9.0000000000000897 · Cited by 20
Baba, M., Takatsuna, H., Matsui, N., & Ohwada, S. (2020) · Journal of Pain Research · doi:10.2147/jpr.s255345 · Cited by 20
Xu, X., Chen, R., Yu, Y., Yang, J., Lin, C., & Liu, R. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111419 · Cited by 19
Yuan, B.-T., Li, M., Zhu, L.-P., Xu, M., Gu, J., Gao, Y., & Ma, L.-J. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116427 · Cited by 19
Fang, Y., Chen, C., Zhong, Q., Wang, L., Gui, Z., Zhu, J., Manyande, A., Xu, F., Wang, J., & Zhang, Z. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02816-4 · Cited by 17
Jensen, J., Pitcher, M. H., Yuan, Z., Ramsden, C. E., & Domenichiello, A. F. (2018) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2018.07.015 · Cited by 17
Topham, L., Grégoire, S., Kang, H., Salmon‐Divon, M., Lax, E., Millecamps, M., Moshe Szyf, A., & Stone, L. S. (2021) · PAIN Reports · doi:10.1097/pr9.0000000000000944 · Cited by 18
Zhu, X., Zhang, C., Hu, Y., Wang, Y., Xiao, S., Zhu, Y., Sun, H., Sun, J., Xu, C., Xu, Y., et al. (2024) · eNeuro · doi:10.1523/eneuro.0454-23.2024 · Cited by 17
Tang, Y., Wu, J., Liu, C., Chen, H., Sun, Y., Xu, X., Gan, L., Tao, Y., Ye, S., Song, J., et al. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03081-z · Cited by 15
Elina, K. C., Moon, H. C., Kim, S., Kim, H. K., Won, S.-Y., Hyun, S., & Park, Y. S. (2019) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.13059 · Cited by 15
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Kim, J., Lee, J., Song, H., Koo, J. W., & Kang, S. (2025) · Neural Plasticity · doi:10.1155/np/7259018 · Cited by 14
Hara, A. C. P., Aching, N. C., Marques, L. M., Fregni, F., Battistella, L. R., & Simis, M. (2022) · Spinal Cord · doi:10.1038/s41393-022-00831-9 · Cited by 15
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Norris, M. R., Becker, L. J., Bilbily, J., Chang, Y. A., Borges, G., Dunn, S. S., Madasu, M. K., Vazquez, C. R., Cariello, S. A., Al‐Hasani, R., et al. (2023) · Pain · doi:10.1097/j.pain.0000000000003123 · Cited by 14
Zou, H., Pu, W., Zhou, J., Li, J., Ma, L., Wang, S., Liu, C., Mou, J., Liu, X., Yu, T., et al. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70360 · Cited by 14
Brandão, A. D. F., Bonet, I. J. M., Pagliusi, M., Zanetti, G. G., Pho, N., Tambeli, C. H., Parada, C. A., Vieira, A. S., & Sartori, C. R. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01453 · Cited by 13
Function, regulation, and pharmacological effects of pregnenolone in the central nervous system
Lin, Y. C., Cheung, G., Espinoza, N., & Papadopoulos, V. (2021) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2021.100310 · Cited by 14
Zeng, P., Huang, J., Wu, S., Qian, C., Chen, F., Sun, W., Tao, W., Liao, Y., Zhang, J., Yang, Z., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00534 · Cited by 13
Xiao, C., Liu, D., Du, J., Guo, Y., Deng, Y., Hei, Z., & Li, X. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.11.020 · Cited by 13
Neuropathic pain as a trigger for histone modifications in limbic circuitry
Bryant, S., Rodier, J.-A., Geiger, L. T., Barker, D. J., & Peña, C. J. (2022) · Genes Brain & Behavior · doi:10.1111/gbb.12830 · Cited by 11
Chen, L., Gui, X., Tian, W.-D., Kan, H., Huang, J.-Z., & Ji, F. (2024) · World Journal of Psychiatry · doi:10.5498/wjp.v14.i8.1254 · Cited by 12
Wang, J., Zhao, Q., Zhou, Y., Sun, W., Han, S., Peng, Y., Li, J., & Han, R. (2019) · Journal of Neurosurgical Anesthesiology · doi:10.1097/ana.0000000000000610 · Cited by 12
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Li, H., Wan, H., Zhao, H., Luan, S., & Zhang, C. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4305 · Cited by 12
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Ramírez‐López, A., Pastor, A., de la Torre, R., Porta, C. L., Ozaita, A., Cabañero, D., & Maldonado, R. J. (2021) · European Journal of Pain · doi:10.1002/ejp.1753 · Cited by 11
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Awad-Igbaria, Y., Abu-Ata, S., Francis, Y. N., Lowenstein, L., Ginat, K., Bornstein, J., Palzur, E., & Shamir, A. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109788 · Cited by 10
Xu, C., Zheng, H., Liu, T., Zhang, Y., & Feng, Y. (2021) · International Journal of Surgery · doi:10.1016/j.ijsu.2021.106140 · Cited by 10
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Wang, Y. (2024) · ImmunoHorizons · doi:10.4049/immunohorizons.2400004 · Cited by 9
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Yu, Y., Xia, S.-H., Xu, Z., Zhao, W.-N., Song, L., Pan, X., Zhong, C., Wang, D., Gao, Y., Yang, J., et al. (2025) · Current Biology · doi:10.1016/j.cub.2025.02.055 · Cited by 9
Shiers, S. I., Elahi, H., Hennen, S., & Price, T. J. (2021) · Neurobiology of Pain · doi:10.1016/j.ynpai.2021.100081 · Cited by 9
Pollema‐Mays, S. L., Centeno, M. V., Chang, Z., Apkarian, A. V., & Martina, M. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.11.036 · Cited by 9
Xu, S., Yi, Y., Wang, Y., Wang, P., Zhao, Y., & Feng, W. S. (2022) · Journal of Pain Research · doi:10.2147/jpr.s378893 · Cited by 8
Farghaly, H. S. M., Elbadr, M. M., Ahmed, M. A., & Abdelhaffez, A. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116752 · Cited by 8
Vivanco-Estela, A. N., da Rocha, S. A., Escobar-Espinal, D. M., Bálico, G. G., Caudle, R. M., Guimarães, F. S., Del-Bel, E., & Nascimento, G. C. (2025) · Pain · doi:10.1097/j.pain.0000000000003616 · Cited by 7
Ni, H., Zhou, Z., Estill, M. S., Halawani, D., Alves, C. J., Shen, L., Xie, N., Friedel, R. H., & Zou, H. (2025) · Nature Communications · doi:10.1038/s41467-025-65095-2 · Cited by 8
Self-citation
Metadata
- Authors
- Descalzi, G., Mitsi, V., Purushothaman, I., Gaspari, S., Avrampou, K., Loh, Y.-H. E., Shen, L., & Zachariou, V.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Corresponding author
- Zachariou, Venetia
- ORCID
- Venue
- Science Signaling
- Published
- 2017-03-21
- Volume
- 10
- Issue
- 471
- ISSN
- 1937-9145 (ISSN-L)
- 1945-0877
- PMC
- PMC5524975
- OpenAlex
- W2600178581
- Cited by
- 188
- References
- 171
- Citations by year
- 2026: 15 · 2025: 21 · 2024: 21 · 2023: 22 · 2022: 18 · 2021: 28 · 2020: 17 · 2019: 26 · 2018: 12 · 2017: 6
- FWCI
- 12.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Signaling (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (award287707)
- National Institute of Neurological Disorders and Stroke (award287708)
- Banting Research Foundation (award287709)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- neuropathic pain, depression, chronic stress, gene expression, transcriptome, nucleus accumbens, medial prefrontal cortex, periaqueductal gray, spared nerve injury, chronic unpredictable mild stress, signaling pathways, anxiety
- MeSH terms
- Adaptation, Physiological, Animals, Brain, Depression, Gene Expression Regulation, Mice, Inbred C57BL, Nerve Net, Neuralgia, Nucleus Accumbens, Periaqueductal Gray, Stress, Psychological, Signal Transduction, Cluster Analysis, Prefrontal Cortex, Mice, Knockout, Gene Expression Profiling, Chronic Pain
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