Alzheimer’s Disease: The Challenge of the Second Century

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864

A default mode of brain function

Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190

Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359

The Clinical Dementia Rating (CDR): Current version and scoring rules

Morris, J. C. (1993) · Neurology · doi:10.1212/wnl.43.11.2412-a · Cited by 9,882

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429

Finding the missing heritability of complex diseases

Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature · doi:10.1038/nature08494 · Cited by 8,336

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

Jack, C. R., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C., & Trojanowski, J. Q. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70299-6 · Cited by 4,806

Nanoparticle Assisted Regulation of Nucleation Pathway of Amyloid Tetramer and Inhibition of Their Fibrillation Kinetics

Mondal, S., Chowdhury, S. R., Shah, M., Kumar, V., Kumar, S., & Iyer, P. K. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.9b00128 · Cited by 18

Evodiamine derivatives improve cognitive abilities in APPswe/PS1ΔE9 transgenic mouse models of Alzheimer's disease

Pang, S., Sun, C., Gao, S., Yang, Y., Pan, X., & Zhang, L. (2020) · Animal Models and Experimental Medicine · doi:10.1002/ame2.12126 · Cited by 18

The potential roles of genetic factors in predicting ageing-related cognitive change and Alzheimer’s disease

Pan, G., King, A. E., Wu, F., Simpson, S., Woodhouse, A., Phipps, A., & Vickers, J. C. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101402 · Cited by 19

HEBP1 - An early trigger for neuronal cell death and circuit dysfunction in Alzheimer’s disease

Chua, J. J. E. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.07.005 · Cited by 18

APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study

Iacono, D., Zandi, P. P., Gross, M. D., Markesbery, W. R., Pletniková, O., Rudow, G. L., & Troncoso, J. C. (2015) · Oncotarget · doi:10.18632/oncotarget.4118 · Cited by 18

A Therapeutic Approach for Senile Dementias: Neuroangiogenesis

Ambrose, C. T. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-140498 · Cited by 18

Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice

Lillehaug, S., Skaaraas, G. H. E. S., Nilsson, L. N. G., Bjaalie, J. G., Leergaard, T. B., & Torp, R. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.09.013 · Cited by 18

Protective effect of tetrahydroxy stilbene glucoside on learning and memory by regulating synaptic plasticity

Shi, X., Luo, H.-B., Li, Y., Liu, Z.-J., Cao, L., Zhang, Z.-Q., Wang, Y., Zhang, X., & Liu, Z. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.191223 · Cited by 18

The value of whole-brain CT perfusion imaging and CT angiography using a 320-slice CT scanner in the diagnosis of MCI and AD patients

Zhang, B., Gu, G.-J., Jiang, H., Guo, Y. C., Shen, X., Li, B., & Zhang, W. (2017) · European Radiology · doi:10.1007/s00330-017-4865-1 · Cited by 18

Oil Palm Phenolics Inhibit theIn VitroAggregation ofβ-Amyloid Peptide into Oligomeric Complexes

Weinberg, R. P., Koledova, V. V., Shin, H., Park, J. H., Tan, Y., Sinskey, A. J., Sambanthamurthi, R., & Rha, C. (2018) · International Journal of Alzheimer s Disease · doi:10.1155/2018/7608038 · Cited by 18

FRET-Based Calcium Imaging: A Tool for High-Throughput/Content Phenotypic Drug Screening in Alzheimer Disease

Honarnejad, K., Kirsch, A. K., Daschner, A., Szybińska, A., Kuźnicki, J., & Herms, J. W. (2013) · SLAS DISCOVERY · doi:10.1177/1087057113502672 · Cited by 18

Pathogenesis and therapeutic applications of microglia receptors in Alzheimer’s disease

Fu, J., Wang, R., He, J., Liu, X., Wang, X., Yao, J., Liu, Y., Ran, C., Ye, Q., & He, Y. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1508023 · Cited by 17

Imaging Amyloid and Tau in the Retina: Current Research and Future Directions

Tang, M. Y., Blazes, M. S., & Lee, C. S. (2023) · Journal of Neuro-Ophthalmology · doi:10.1097/wno.0000000000001786 · Cited by 17

Population pharmacokinetic and pharmacodynamic analysis of plasma Aβ40and Aβ42following single oral doses of the BACE1 inhibitor AZD3839 to healthy volunteers

Quartino, A. L., Huledal, G., Sparve, E., Lüttgen, M., Bueters, T., Karlsson, P., Olsson, T., Paraskos, J., Maltby, J., Claeson‐Bohnstedt, K., et al. (2014) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.130 · Cited by 17

Enantiomeric lignans with anti-β-amyloid aggregation activity from the twigs and leaves of Pithecellobium clypearia Benth

Wang, Y.-X., Zhou, L., Wang, J., Lin, B., Wang, X., Huang, X., & Song, S. (2018) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2018.02.001 · Cited by 17

EphA4 regulates Aβ production via BACE1 expression in neurons

Tamura, K., Chiu, Y., Shiohara, A., Hori, Y., & Tomita, T. (2020) · The FASEB Journal · doi:10.1096/fj.202001510r · Cited by 17

Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors

Ahuja‐Casarín, A. I., Merino‐Montiel, P., Vega-Báez, J. L., Montiel‐Smith, S., Fernandes, M. X., Lagunes, I., Maya, I., Padrón, J. M., López, Ó., & Fernández‐Bolaños, J. G. (2020) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2020.1847101 · Cited by 17

An fMRI Feature Selection Method Based on a Minimum Spanning Tree for Identifying Patients with Autism

Shi, C., Zhang, J., & Wu, X. (2020) · Symmetry · doi:10.3390/sym12121995 · Cited by 17

The Psen1‐L166P ‐knock‐in mutation leads to amyloid deposition in human wild‐type amyloid precursor protein YAC transgenic mice

Vidal, R., Sammeta, N., Garringer, H. J., Sambamurti, K., Miravalle, L., Lamb, B. T., & Ghetti, B. F. (2012) · The FASEB Journal · doi:10.1096/fj.12-205542 · Cited by 17

Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy

Ochałek, A., Szczęsna, K., Petazzi, P., Kobolák, J., & Dinnyés, A. (2016) · Stem Cells International · doi:10.1155/2016/5838934 · Cited by 17

TRPC Channels and Alzheimer’s Disease

Lu, R., Qian, H., & Wang, J. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-94-024-1088-4_7 · Cited by 17

Proteomics Time-Course Study of App Knock-In Mice Reveals Novel Presymptomatic Aβ42-Induced Pathways to Alzheimer’s Disease Pathology

Schedin‐Weiss, S., Nilsson, P., Matton, A., Axenhus, M., Sekiguchi, M., Saito, T., Winblad, B. G., Saido, T. C., & Tjernberg, L. O. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200028 · Cited by 17

Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease

Svedružić, Ž. M., Popović, K., & Jengić, V. Š. (2015) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2015.06.002 · Cited by 17

Reduction of Amyloid-β Deposition and Attenuation of Memory Deficits by Tolfenamic Acid

Subaiea, G. M., Ahmed, A. H., Adwan, L. I., & Zawia, N. H. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-132726 · Cited by 17

Extremely Low-Frequency Magnetic Exposure Appears to Have No Effect on Pathogenesis of Alzheimer’s Disease in Aluminum-Overloaded Rat

Zhang, C., Li, Y., Wang, C., Lv, R., & Song, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071087 · Cited by 17

Probiotic-fermented ginger-processed Gastrodia elata BI. Ameliorates AlCl3-induced cognitive dysfunction in an Alzheimer's disease rat model by regulating the gut microbiota and CREB/BDNF pathway

Huang, J., Lai, L., Su, Y., Chen, J., Li, P., & Du, B. (2025) · Food Research International · doi:10.1016/j.foodres.2025.116087 · Cited by 16

The Role of the Urea Cycle in the Alzheimer's Disease Brain

Al‐Thani, N. A., Stewart, G. S., & Costello, D. A. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70033 · Cited by 16

Pre-clinical Evidence-based Neuroprotective Potential of Naringin against Alzheimer’s Disease-like Pathology: A Comprehensive Review

Singh, A., & Singh, N. K. (2023) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201024666230801095526 · Cited by 16

Reduced Sulfotransferase SULT2A1 Activity in Patients With Alzheimer´s Disease

Vaňková, M., Hill, M., Velíková, M., Včelák, J., Vacínová, G., Lukášová, P., Vejražková, D., Dvořáková, K., Rusina, R., Holmerová, I., et al. (2015) · Physiological Research · doi:10.33549/physiolres.933160 · Cited by 16

Valproic acid ameliorates olfactory dysfunction in APP/PS1 transgenic mice of Alzheimer's disease: Ameliorations from the olfactory epithelium to the olfactory bulb

Yao, Z., Jing, H., Wang, D., Lv, B., Li, J., Liu, F.-F., Fan, H., Sun, X., Qin, Y., & Zhao, M. (2016) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2016.02.012 · Cited by 16

Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype

Whitehouse, I. J., Brown, D., Baybutt, H. N., Diack, A. B., Kellett, K. A. B., Piccardo, P., Manson, J. C., & Hooper, N. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159119 · Cited by 16

A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation

Kundra, R., Dobson, C. M., & Vendruscolo, M. (2020) · iScience · doi:10.1016/j.isci.2020.100934 · Cited by 16

Comprehensive chemical profiling of Jia-Wei-Qi-Fu-Yin and its network pharmacology-based analysis on Alzheimer's disease

An, H.-M., Da-rong, H., Yang, H. Q., Liu, X., Du, J., Li, Y., Li, C., Pang, H., Liu, R., Peng, C., et al. (2020) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2020.113467 · Cited by 16

How Mutations Perturb γ-Secretase Active Site Studied by Free Energy Simulations

Chen, S., & Zacharias, M. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00440 · Cited by 16

[18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

Hsieh, C., Hou, C., Zhu, Y., Lee, J. Y., Kohli, N., Gallagher, E. P., Xu, K., Lee, H. S., Li, S., McManus, M. J., et al. (2022) · EJNMMI Research · doi:10.1186/s13550-022-00914-x · Cited by 16

Pathophysiological Association Between Diabetes Mellitus and Alzheimer's Disease

Agrawal, M., & Agrawal, A. K. (2022) · Cureus · doi:10.7759/cureus.29120 · Cited by 16

APP/PS1 Gene-Environmental Cadmium Interaction Aggravates the Progression of Alzheimer’s Disease in Mice via the Blood-Brain Barrier, Amyloid-β, and Inflammation

Liu, J., Xie, Y., Lu, Y., Zhao, Z., Zhuang, Z., Yang, L., Huang, H., Li, H., Mao, Z., Pi, S., et al. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221205 · Cited by 16

The Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations

Bakır-Güngör, B., & Sezerman, O. U. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057022 · Cited by 16

Early-stage reduction of the dendritic complexity in basolateral amygdala of a transgenic mouse model of Alzheimer's disease

Guo, C., Long, B., Hu, Y., Yuan, J., Gong, H., & Li, X. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.03.094 · Cited by 16

Prevalence and Incidence of Statin Use and 3-Year Adherence and Discontinuation Rates Among Older Adults With Dementia

Ofori‐Asenso, R., Ilomäki, J., TACEY, M. A., Curtis, A. J., Zomer, E., Bell, J. S., Zoungas, S., & Liew, D. (2018) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317518787314 · Cited by 16

In vivo characterization of a bigenic fluorescent mouse model of Alzheimer’s disease with neurodegeneration

Crowe, S. E., & Ellis‐Davies, G. C. R. (2013) · Journal of Comparative Neurology · doi:10.1002/cne.23306 · Cited by 15

The reduction of astrocytic tau prevents amyloid-β-induced synaptotoxicity

Cisternas, P., Taylor, X., Martínez, P., Maldonado, O., Jury, N., & Lasagna‐Reeves, C. A. (2022) · Brain Communications · doi:10.1093/braincomms/fcac235 · Cited by 15

Insomnia Symptoms and Biomarkers of Alzheimer’s Disease in the Community

Nicolazzo, J., Cavuoto, M. G., Rowsthorn, E., Cribb, L., Bransby, L., Gibson, M., Wall, P., Velakoulis, D., Eratne, D., Buckley, R. F., et al. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-220924 · Cited by 15

An inclusive study of recent advancements in Alzheimer's disease: A comprehensive review

Singh, S., Mahajan, M., Kumar, D., Singh, K., Chowdhary, M., & Amit (2023) · Neuropeptides · doi:10.1016/j.npep.2023.102369 · Cited by 15

Astrocytes in Amyloid Generation and Alcohol Metabolism: Implications of Alcohol Use in Neurological Disorder(s)

Kumar, M., Swanson, N., Ray, S., Buch, S. J., Saraswathi, V., & Sil, S. (2024) · Cells · doi:10.3390/cells13141173 · Cited by 15

Cognitive resilience to Alzheimer's disease characterized by cell‐type abundance

O’Neill, N. K., Stein, T. D., Olayinka, O. A., Empawi, J. A., Hu, J., Tong, T., Zhang, X., & Farrer, L. A. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14187 · Cited by 15

Basement membranes’ role in immune cell recruitment to the central nervous system

Wright, S. A., Lennon, R., & Greenhalgh, A. D. (2024) · Journal of Inflammation · doi:10.1186/s12950-024-00426-6 · Cited by 17

Cannabinoids: Role in Neurological Diseases and Psychiatric Disorders

Kumar, U. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms26010152 · Cited by 15

Hologram QSAR Models of a Series of 6-Arylquinazolin-4-Amine Inhibitors of a New Alzheimer’s Disease Target: Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase-1A Enzyme

Leal, F. D., Lima, C. H. D. S., de Alencastro, R. B., Castro, H. C., Rodrigues, C. R., & Albuquerque, M. G. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16035235 · Cited by 15

Specific aromatic foldamers potently inhibit spontaneous and seeded Aβ42 and Aβ43 fibril assembly

Seither, K. M., McMahon, H. A., Singh, N., Wang, H. H., Cushman-Nick, M., Montalvo, G. L., DeGrado, W. F., & Shorter, J. (2014) · Biochemical Journal · doi:10.1042/bj20131609 · Cited by 15

Conformational evolution of polymorphic amyloid assemblies

Chen, L., Hsieh, M.-C., Li, N. X., & Lynn, D. G. (2018) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2018.04.004 · Cited by 15

Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes

Kamp, F., Scheidt, H. A., Winkler, E., Basset, G., Heinel, H., Hutchison, J. M. S., LaPointe, L. M., Sanders, C. R., Steiner, H., & Huster, D. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00068 · Cited by 15

Lipid Metabolism in Late-Onset Alzheimer’s Disease Differs from Patients Presenting with Other Dementia Phenotypes

Sarrafpour, S., Ormseth, C. H., Chiang, A. J., Arakaki, X., Harrington, M. G., & Fonteh, A. N. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16111995 · Cited by 15

Interplay Between Macular Retinal Changes and White Matter Integrity in Early Alzheimer’s Disease

Alves, C., Jorge, L., Canário, N., Santiago, B., Santana, I. J., Castelhano, J., Ambrósio, A. F., Bernardes, R., & Castelo-Branco, M. S. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190152 · Cited by 15

Leukotriene Receptor Antagonist Use and Dementia Risk in Patients With Asthma: A Retrospective Cohort Study

ISHIKURA, Y., Maeda‐Minami, A., HOSOKAWA, M., Onoda, A., Kawano, Y., Ihara, T., Sugamata, M., Takeda, K., & Mano, Y. (2021) · In Vivo · doi:10.21873/invivo.12625 · Cited by 15

Evaluation of the Predictive Ability and User Acceptance of Panoramix 2.0, an AI-Based E-Health Tool for the Detection of Cognitive Impairment

Valladares‐Rodríguez, S., Iglesias, M. J. F., Anido, L., & Pacheco-Lorenzo, M. R. (2022) · Electronics · doi:10.3390/electronics11213424 · Cited by 15

The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression

Corsi, G. I., Gadekar, V. P., Haukedal, H., Doncheva, N. T., Anthon, C., Ambardar, S., Palakodeti, D., Hyttel, P., Freude, K., Seemann, S. E., et al. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105980 · Cited by 15

Structural Proteomic Profiling of Cerebrospinal Fluids to Reveal Novel Conformational Biomarkers for Alzheimer’s Disease

Wang, B., Zhong, X., Fields, L. G., Lu, H., Zhu, Z., & Li, L. (2023) · Journal of the American Society for Mass Spectrometry · doi:10.1021/jasms.2c00332 · Cited by 15

Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis

Ulku, I., Liebsch, F., Åkerman, S., Schulz, J. F., Kulic, L., Höck, C., Pietrzik, C. U., Spiezio, A. D., Thinakaran, G., Säftig, P., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-28846-z · Cited by 15

Emerging trends in IRAK-4 kinase research

Yadav, H. K., & Shirumalla, R. K. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08438-w · Cited by 15

Mind the Gap: Unraveling the Intricate Dance Between Alzheimer’s Disease and Related Dementias and Bone Health

Karnik, S. J., Margetts, T. J., Wang, H. S., Movilă, A., Oblak, A. L., Fehrenbacher, J. C., Kacena, M. A., & Plotkin, L. I. (2024) · Current Osteoporosis Reports · doi:10.1007/s11914-023-00847-x · Cited by 15

Telencephalic neurocircuitry and synaptic plasticity in rodent spatial learning and memory

Pooters, T., der Jeugd, A. V., Callaerts‐Vegh, Z., & D’Hooge, R. (2015) · Brain Research · doi:10.1016/j.brainres.2015.01.015 · Cited by 15

Important advances in Alzheimer’s disease from the use of induced pluripotent stem cells

Majolo, F., Marinowic, D. R., Machado, D. C., & da Costa, J. C. (2019) · Journal of Biomedical Science · doi:10.1186/s12929-019-0501-5 · Cited by 15

Decreased Orexin Receptor 1 mRNA Expression in the Locus Coeruleus in Both Tau Transgenic rTg4510 and Tau Knockout Mice and Accompanying Ascending Arousal System Tau Invasion in rTg4510

Keenan, R. J., Oberrauch, S., Bron, R., Nowell, C. J., Challis, L. M., Hoyer, D., & Jacobson, L. H. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-201177 · Cited by 15

Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration

Todd, K. L., Fossati, S., Ghiso, J. A., & Rostagno, A. A. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.09.010 · Cited by 15

Lipids in Alzheimer’s disease and their potential for therapy

Lütjohann, D., Meichsner, S., & Pettersson, H. I. (2012) · Clinical Lipidology · doi:10.2217/clp.11.74 · Cited by 15

The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers

Stravalaci, M., Tapella, L., Beeg, M., Rossi, A., Joshi, P., Pizzi, E., Mazzanti, M., Balducci, C., Forloni, G., Biasini, E., et al. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150882 · Cited by 15

The Role of Resveratrol in Alzheimer's Disease: A Comprehensive Review of Current Research

Kumar, S., Saha, S., Sharma, B., Singh, S., Shukla, P., Mukherjee, S., Agarwal, M., Singh, K., & Singh, T. (2023) · Current Functional Foods · doi:10.2174/0126668629269244231127071411 · Cited by 14

An Update of Salivary Biomarkers for the Diagnosis of Alzheimer’s Disease

Guo, H., RuiHuan, Y., Cheng, W., Li, Q., & Du, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26052059 · Cited by 14

Alzheimer’s disease risk prediction using machine learning for survival analysis with a comorbidity-based approach

Abuhantash, F., Welsch, R. E., Finkelstein, S. N., & Shehhi, A. A. (2025) · Scientific Reports · doi:10.1038/s41598-025-14406-0 · Cited by 14

Dextran sulfate sodium inhibits amyloid‐β oligomer binding to cellular prion protein

Aimi, T., Suzuki, K., Hoshino, T., & Mizushima, T. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13166 · Cited by 14

Human Serum Albumin-Inspired Glycopeptide-Based Multifunctional Inhibitor of Amyloid-β Toxicity

Roy, R., Pradhan, K., Khan, J., Das, G., Mukherjee, N., Das, D., & Ghosh, S. (2020) · ACS Omega · doi:10.1021/acsomega.0c01028 · Cited by 14

Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease

Munafò, A., Cantone, A. F., Benedetto, G. D., Torrisi, S. A., Burgaletto, C., Bellanca, C. M., Gaudio, G., Broggi, G., Caltabiano, R., Leggio, G. M., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1386224 · Cited by 14

Context dependence of protein misfolding and structural strains in neurodegenerative diseases

Mehta, A. K., Rosen, R. F., Childers, W. S., Gehman, J. D., Walker, L. C., & Lynn, D. G. (2013) · Biopolymers · doi:10.1002/bip.22283 · Cited by 14

In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegeneration

Crowe, S. E., & Ellis‐Davies, G. C. R. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23336 · Cited by 14

Presenilin-1 Regulates the Expression of p62 to Govern p62-dependent Tau Degradation

Tung, Y.-T., Wang, B.-J., Hsu, W., Hu, M., Her, G. M., Huang, W., & Liao, Y. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8482-y · Cited by 14

Processed B-Type Natriuretic Peptide Is a Biomarker of Postinterventional Restenosis in Ischemic Heart Disease

Fujimoto, H., Suzuki, T., Aizawa, K., Sawaki, D., Ishida, J., Ando, J., Fujita, H., Komuro, I., & Nagai, R. (2013) · Clinical Chemistry · doi:10.1373/clinchem.2013.203406 · Cited by 14

Synthesis, biological evaluation and structure-activity relationship studies of hederacolchiside E and its derivatives as potential anti-Alzheimer agents

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One-step synthesized flower-like materials used for sensitively detecting amyloid precursor protein

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