Human COL7A1 -corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa

The Sequence Alignment/Map format and SAMtools

Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R., & 1000 Genome Project Data Processing Subgroup (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp352 · Cited by 62,041

Fast and accurate short read alignment with Burrows-Wheeler transform

Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.211 · Cited by 35,890

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

Wang, K., Li, M., & Hakonarson, H. H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq603 · Cited by 14,724

Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification

Fine, J., Bruckner‐Tuderman, L., Eady, R. A. J., Bauer, E. A., Bauer, J. W., Has, C., Heagerty, A., Hintner, H., Hovnanian, A., Jonkman, M. F., et al. (2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.01.903 · Cited by 934

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

Sommer, C. A., Stadtfeld, M., Murphy, G. J., Hochedlinger, K., Kotton, D. N., & Mostoslavsky, G. (2009) · Stem Cells · doi:10.1634/stemcells.2008-1075 · Cited by 676

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

Mavilio, F., Pellegrini, G., Ferrari, S., Nunzio, F. D., Iorio, E. D., Recchia, A., Maruggi, G., Ferrari, G., Provasi, E., Bonini, C., et al. (2006) · Nature Medicine · doi:10.1038/nm1504 · Cited by 668

Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette

Somers, A., Jean, J.-C., Sommer, C. A., Omari, A., Ford, C. C., Mills, J. A., Ying, L., Sommer, A. G., Jean, J. M., Smith, B. W., et al. (2010) · Stem Cells · doi:10.1002/stem.495 · Cited by 423

iPS cells: a game changer for future medicine

Inoue, H., Nagata, N., Kurokawa, H., & Yamanaka, S. (2014) · The EMBO Journal · doi:10.1002/embj.201387098 · Cited by 414

In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases

Sebastiano, V., Maeder, M. L., Angstman, J. F., Haddad, B., Khayter, C., Yeo, D. T., Goodwin, M. J., Hawkins, J. S., Ramirez, C. L., Batista, L. F. Z., et al. (2011) · Stem Cells · doi:10.1002/stem.718 · Cited by 311

Genome-edited skin epidermal stem cells protect mice from cocaine-seeking behaviour and cocaine overdose

Li, Y., Kong, Q., Yue, J., Gou, X., Xu, M., & Wu, X. (2018) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0293-z · Cited by 26

Differentiation of pluripotent stem cells for modeling human skin development and potential applications

Oceguera-Yañez, F., Ávila-Robinson, A., & Woltjen, K. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1030339 · Cited by 28

A novel defined risk signature based on pyroptosis-related genes can predict the prognosis of prostate cancer

Hu, D., Cao, Q., Tong, M., Ji, C., Li, Z., Huang, W., Jin, Y., Tong, G., Wang, Y., Li, P., et al. (2022) · BMC Medical Genomics · doi:10.1186/s12920-022-01172-5 · Cited by 23

Raising Awareness Among Healthcare Providers about Epidermolysis Bullosa and Advancing Toward a Cure.

Tabor, A., Pergolizzi, J. V., Marti, G. P., Harmon, J. W., Cohen, B. H., & LeQuang, J. A. (2017) · PubMed Central · Cited by 24

iPSC-based approach for human hair follicle regeneration

Vatanashevanopakorn, C., & Sartyoungkul, T. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1149050 · Cited by 25

Regenerative Engineering Approaches to Scar-Free Skin Regeneration

Otsuka, T., Kan, H.-M., & Laurencin, C. T. (2021) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-021-00229-8 · Cited by 23

A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa

Neumayer, G., Torkelson, J. L., Li, S., McCarthy, K., Zhen, H. H., Vangipuram, M., Mader, M. M.-D., Gebeyehu, G., Jaouni, T. M., Jackow, J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49400-z · Cited by 30

Gene editing toward the use of autologous therapies in recessive dystrophic epidermolysis bullosa

Perdoni, C., Osborn, M. J., & Tolar, J. (2015) · Translational research · doi:10.1016/j.trsl.2015.05.008 · Cited by 20

Recent advances in the induced pluripotent stem cell‐based skin regeneration

Choudhury, S., Surendran, N., & Das, A. (2021) · Wound Repair and Regeneration · doi:10.1111/wrr.12925 · Cited by 22

Emerging drugs for the treatment of epidermolysis bullosa

Titeux, M., Claustres, M. B. D., Izmiryan, A., Ragot, H., & Hovnanian, A. (2020) · Expert Opinion on Emerging Drugs · doi:10.1080/14728214.2020.1839049 · Cited by 21

Human pluripotent stem cells: An alternative for 3D in vitro modelling of skin disease

Khurana, P., Kolundžić, N., Flohr, C., & Ilić, D. (2021) · Experimental Dermatology · doi:10.1111/exd.14358 · Cited by 20

The utility of dermal fibroblasts in treatment of skin disorders: A paradigm of recessive dystrophic epidermolysis bullosa

Shams, F., Rahimpour, A., Vahidnezhad, H., Hosseinzadeh, S., Moravvej, H., Kazemi, B., Rajabibazl, M., Abdollahimajd, F., & Uitto, J. (2021) · Dermatologic Therapy · doi:10.1111/dth.15028 · Cited by 17

Improved methods of AAV-mediated gene targeting for human cell lines using ribosome-skipping 2A peptide

Karnan, S., Ota, A., Konishi, Y., Wahiduzzaman, M., Hosokawa, Y., & Konishi, H. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv1338 · Cited by 17

Research Techniques Made Simple: The Application of CRISPR-Cas9 and Genome Editing in Investigative Dermatology

Guitart, J., Johnson, J. L., & Chien, W. W. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.06.007 · Cited by 17

CRISPR-Cas9‒Based Genomic Engineering in Keratinocytes: From Technology to Application

Smits, J. P. H., Meesters, L. D., Maste, B. G. W., Zhou, H., Zeeuwen, P. L. J. M., & van den Bogaard, E. H. J. (2021) · JID Innovations · doi:10.1016/j.xjidi.2021.100082 · Cited by 16

Challenges in Treating Genodermatoses: New Therapies at the Horizon

Morren, M., Legius, E., Giuliano, F., Hadj-Rabia, S., Hohl, D., & Bodemer, C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.746664 · Cited by 17

Culturing human pluripotent stem cells for regenerative medicine

Ozawa, H., Matsumoto, T., & Nakagawa, M. (2023) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2023.2225701 · Cited by 16

Current and future prospects for hemophilia gene therapy

Ward, P., & Walsh, C. (2016) · Expert Review of Hematology · doi:10.1080/17474086.2016.1182859 · Cited by 16

Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing

Hopfner, Ú., Aitzetmüller, M. M., Neßbach, P., Hu, M. S.-M., Machens, H., Maan, Z. N., & Duscher, D. (2018) · Stem Cells International · doi:10.1155/2018/1353085 · Cited by 16

Is hypoimmunogenic stem cell therapy safe in times of pandemics?

Matheus, F., Raveh, T. B., Oro, A. E., Wernig, M., & Drukker, M. (2022) · Stem Cell Reports · doi:10.1016/j.stemcr.2022.02.014 · Cited by 15

Placenta-based therapies for the treatment of epidermolysis bullosa

Nevala-Plagemann, C., Lee, C. A. A., & Tolar, J. (2015) · Cytotherapy · doi:10.1016/j.jcyt.2015.03.006 · Cited by 16

Research on genodermatoses using novel genome‐editing tools

Lehmann, J., Seebode, C., & Emmert, S. (2017) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/ddg.13270 · Cited by 17

A Systematic Review of Stem Cell Differentiation into Keratinocytes for Regenerative Applications

Hazrati, R., Davaran, S., Keyhanvar, P., Soltani, S., & Alizadeh, E. (2023) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10636-9 · Cited by 17

Integrated Genomic Medicine

Schork, N. J., & Nazor, K. L. (2017) · Advances in genetics · doi:10.1016/bs.adgen.2017.06.001 · Cited by 16

Rare Genetic Disorders: Novel Treatment Strategies and Insights Into Human Biology

Koch, P. J., & Koster, M. I. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.714764 · Cited by 18

Therapies for inherited skin fragility disorders

Has, C., & Kiritsi, D. (2015) · Experimental Dermatology · doi:10.1111/exd.12666 · Cited by 16

“…Rewritten in the Skin”: Clues to Skin Biology and Aging from Inherited Disease

Monnat, R. J. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.88 · Cited by 13

Research Techniques Made Simple: Delivery of the CRISPR/Cas9 Components into Epidermal Cells

Shi, H., Smits, J. P. H., van den Bogaard, E. H. J., & Brewer, M. G. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2021.01.008 · Cited by 14

Differentiation of Human Induced Pluripotent Stem Cells into Keratinocytes

Koch, P. J., Webb, S., Gugger, J. A., Salois, M. N., & Koster, M. I. (2022) · Current Protocols · doi:10.1002/cpz1.408 · Cited by 13

Stem cell regenerative potential for plastic and reconstructive surgery

Boháč, M., Csöbönyeiová, M., Kupcová, I., Zamborský, R., Fedeleš, J., & Koller, J. (2016) · Cell and Tissue Banking · doi:10.1007/s10561-016-9583-4 · Cited by 14

Gene Replacement Therapies for Genodermatoses: A Status Quo

Koller, U., & Bauer, J. W. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.658295 · Cited by 13

A Biologic Velcro Patch

Tolar, J., & Wagner, J. E. (2015) · New England Journal of Medicine · doi:10.1056/nejmcibr1414709 · Cited by 12

Biologic Skin Substitutes

Boyce, S. T., & Supp, D. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801654-1.00011-5 · Cited by 12

From Marrow to Matrix: Novel Gene and Cell Therapies for Epidermolysis Bullosa

Webber, B. R., & Tolar, J. (2015) · Molecular Therapy · doi:10.1038/mt.2015.47 · Cited by 13

Role of Actin Cytoskeleton in the Regulation of Epithelial Cutaneous Stem Cells

Yang, G. N., Kopecki, Z., & Cowin, A. J. (2016) · Stem Cells and Development · doi:10.1089/scd.2016.0051 · Cited by 12

dsRNA Sensing Induces Loss of Cell Identity

Rongying, Z., Wang, G., Kim, D.-W., Kim, S., Islam, N., Chen, R., Wang, Z., Li, A., McCarthy, E. F., Li, L., et al. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.07.021 · Cited by 11

CRISPR/Cas9 gene editing for genodermatoses: progress and perspectives

Naso, G., & Petrova, A. (2019) · Emerging Topics in Life Sciences · doi:10.1042/etls20180148 · Cited by 12

Evaluating the Genomic Parameters Governing rAAV-Mediated Homologous Recombination

Spector, L. P., Tiffany, M. R., Ferraro, N. M., Abell, N. S., Montgomery, S. B., & Kay, M. A. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.11.025 · Cited by 12

Epigenetic regulation and signalling pathways in Merkel cell development

Oss-Ronen, L., & Cohen, I. (2021) · Experimental Dermatology · doi:10.1111/exd.14415 · Cited by 14

Review of the Latest Methods of Epidermolysis Bullosa and Other Chronic Wounds Treatment Including BIOOPA Dressing

Nita, M., Pliszczyński, J., Kosieradzki, M., & Fiedor, P. S. (2021) · Dermatology and Therapy · doi:10.1007/s13555-021-00578-w · Cited by 13

Challenges and progress related to gene editing in rare skin diseases

Hofbauer, J. P., Guttmann‐Gruber, C., Wally, V., Sharma, A. K., Gratz, I. K., & Koller, U. (2024) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2024.115294 · Cited by 13

Patent landscape of molecular and cellular targeted therapies for recessive dystrophic epidermolysis bullosa

Alcorte, M. D., Sogayar, M. C., & Demasi, M. A. A. (2019) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2019.1608181 · Cited by 11

Advances in gene editing strategies for epidermolysis bullosa

Köcher, T., & Koller, U. (2021) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2020.12.007 · Cited by 11

Bullous Disorders of Childhood

Paller, A. S., & Mancini, A. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-24475-6.00013-3 · Cited by 11

The Molecular Revolution in Cutaneous Biology: Emerging Landscape in Genomic Dermatology: New Mechanistic Ideas, Gene Editing, and Therapeutic Breakthroughs

Titeux, M., Izmiryan, A., & Hovnanian, A. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.08.038 · Cited by 9

Seven novel COL7A1 mutations identified in patients with recessive dystrophic epidermolysis bullosa from Mexico

Saeidian, A. H., Youssefian, L., Moreno‐Treviño, M. G., Fortuna, G., Vahidnezhad, H., Atanasova, V. S., Uitto, J., Salas-Alanis, J. C., & South, A. P. (2018) · Clinical and Experimental Dermatology · doi:10.1111/ced.13407 · Cited by 10

A 3D in vitro model of the dermoepidermal junction amenable to mechanical testing

Jung, J. P., Lin, W., Riddle, M. J., Tolar, J., & Ogle, B. M. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36519 · Cited by 10

Genome editing strategies for targeted correction of β-globin mutation in sickle cell disease: From bench to bedside

Butt, H., Sathish, S., London, E., Johnson, T. L., Essawi, K., Leonard, A. K., Tisdale, J. F., & Demirci, S. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.03.047 · Cited by 12

A Review of CRISPR-Based Advances in Dermatological Diseases

Lu, X., & Jin, H. (2023) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-023-00642-5 · Cited by 9

Reducing alcohol and/or cocaine-induced reward and toxicity via an epidermal stem cell-based gene delivery platform

Kong, Q., Li, Y., Yue, J., Wu, X., & Xu, M. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01043-y · Cited by 10

A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

Yang, Y., McCullough, C. G., Seninge, L., Guo, L., Kwon, W.-J., Zhang, Y., Li, N. Y., Gaddam, S., Pan, C., Zhen, H. H., et al. (2023) · Developmental Cell · doi:10.1016/j.devcel.2024.12.030 · Cited by 9

Directed differentiation of human pluripotent stem cells into epidermal keratinocyte-like cells

Ali, G., & Abdelalim, E. M. (2022) · STAR Protocols · doi:10.1016/j.xpro.2022.101613 · Cited by 8

Skin Fragility: Perspectives on Evidence-based Therapies

Bruckner‐Tuderman, L. (2020) · Acta Dermato Venereologica · doi:10.2340/00015555-3398 · Cited by 11

Gene Therapy for Inherited Skin Disorders

Lwin, S. M., & McGrath, J. A. (2017) · Wiley eBooks · doi:10.1002/9780470015902.a0026940 · Cited by 8

Stem Cells and Regenerative Strategies for Wound Healing: Therapeutic and Clinical Implications

Garg, A., Garg, S., Adlak, P., Kori, M. L., & Lodhi, S. (2024) · Current Pharmacology Reports · doi:10.1007/s40495-024-00352-4 · Cited by 10

Generation of keratinocyte stem‐like cells from human fibroblasts via a direct reprogramming approach

Zhao, A., Yang, Y., Pan, X., Pan, Y., & Cai, S. (2020) · Biotechnology Progress · doi:10.1002/btpr.2961 · Cited by 7

Congenital epidermolysis bullosa: modern methods of diagnosis and therapy. Prospects for regenerative medicine

Kubanov, A. A., Karamova, A. Е., & Monchakovskaya, E. S. (2020) · Vestnik dermatologii i venerologii · doi:10.25208/vdv551-2020-96-1-10-17 · Cited by 6

Surgical Treatment of Wounds Using Stem Cells in Epidermolysis Bullosa (EB)

Nita, M., Pliszczyński, J., Eljaszewicz, A., Moniuszko, M., Ołdak, T., Woźniak, K., Majewski, S. T., Kowaléwski, C., Kamiński, A., Śladowski, D., et al. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.97036 · Cited by 6

The three-body problem of therapy with induced pluripotent stem cells

Tolar, J., & McGrath, J. A. (2015) · Genome Medicine · doi:10.1186/s13073-015-0141-7 · Cited by 6

Improving Upper-limb Prosthesis Usability: Cognitive Workload Measures Quantify Task DifficultyPreprint

Paskett, M. D., Garcia, J. K., Jones, S. T., Brinton, M. R., Davis, T. S., Duncan, C. C., Cooper, J. M., Strayer, D. L., & Clark, G. A. (2022) · medRxiv · doi:10.1101/2022.08.02.22278038 · Cited by 6

Hippo cooperates with p53 to maintain foregut homeostasis and suppress the malignant transformation of foregut basal progenitor cells

Jiang, Y., Huang, H., Liu, J., Luo, D., Mu, R., Yuan, J., Lin, J., Chen, Q., Tao, W., Yang, L., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2320559121 · Cited by 5

Recent progress in the identification and in vitro culture of skin organoids

Huang, Y., Ye, Q., Wang, J., Kaimin, Z., Yang, H., Jiang, X., & Shen, M. (2025) · Regenerative Therapy · doi:10.1016/j.reth.2025.01.001 · Cited by 8

Advances in Genetic Reprogramming: Prospects from Developmental Biology to Regenerative Medicine

Dhanjal, D. S., Singh, R., Sharma, V., Nepovimová, E., Adam, V., Kuča, K., & Chopra, C. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867330666230503144619 · Cited by 5

Single stem cell gene therapy for genetic skin disease

Larsimont, J., & Blanpain, C. (2015) · EMBO Molecular Medicine · doi:10.15252/emmm.201404859 · Cited by 6

Use of Stem Cells in Wound Healing

Aronson, A., Laageide, L. G., & Powers, J. G. (2018) · Current Dermatology Reports · doi:10.1007/s13671-018-0233-x · Cited by 6

Assessing the zoonotic potential of a novel bat morbillivirusPreprint

Ikegame, S., Carmichael, J. C., Wells, H., O’Brien, R. L. F., Acklin, J. A., Chiu, H.-P., Oguntuyo, K. Y., Cox, R. M., Patel, A. R., Kowdle, S., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.17.460143 · Cited by 5

Mitochondrial Responses to Conventional and Ultra-High Dose Rate (FLASH) Radiation

Caggiano, E. G., Elizondo, M. E., Lopez-Hernandez, A., Waldrop, T., Liu, K., Gatica-Gutierrez, H., Vargas-Hernández, S., Mims, N., Acevedo-Diaz, A., Velasquez, B., et al. (2026) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2026.07.006 · Cited by 4

Current Applications for Bioengineered Skin

Guerrero‐Aspizua, S., Conti, C. J., Zapatero-Solana, E., Larcher, F., & Río, M. D. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800548-4.00008-5 · Cited by 4

Stem Cell Therapies for Tissue Regeneration and Wound Healing: Strategies to Enhance Therapeutic Effectiveness

Mihalceanu, S., Aitzetmüller, M. M., Machens, H., & Duscher, D. (2019) · Springer eBooks · doi:10.1007/978-3-030-19958-6_18 · Cited by 4

A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing

Klementieva, N. V., Goliusova, D. V., Krupinova, J. A., Yanvarev, V., Panova, A. V., Mokrysheva, N., & Киселев, С. Л. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222112054 · Cited by 4

Skin wound healing: The critical role of angiogenesis

Nazarnezhad, S., Kargozar, S., & Hamblin, M. R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821867-9.00022-6 · Cited by 4

Induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa.

Spiliοpoulos, S., & Davanos, N. (2015) · PubMed Central · doi:10.3978/j.issn.2305-5839.2015.09.42 · Cited by 4

Direct reprogramming of somatic cells: an update

Pham, P. V. (2015) · Biomedical Research and Therapy · doi:10.7603/s40730-015-0008-y · Cited by 3

Venturing into the New Science of Nucleases

Tolarová, M., McGrath, J. A., & Tolar, J. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.01.021 · Cited by 3

Induced Pluripotent Stem Cells: Advances and Applications in Regenerative Medicine

Kizub, I. V., Rozhok, A. I., & Bilousova, G. (2023) · Biochemistry · doi:10.5772/intechopen.109274 · Cited by 3

Dachsous is a key player in epithelial wound closure through modulating cell shape changes and tissue mechanics

Porfírio-Rodrigues, P., Pereira, T., Jacinto, A., & Carvalho, L. (2025) · Journal of Cell Science · doi:10.1242/jcs.263674 · Cited by 3

Pluripotent Stem Cell Differentiation Toward Functional Basal Stratified Epithelial Cells

Soares, E., & Zhou, H. (2020) · Methods in molecular biology · doi:10.1007/7651_2020_301 · Cited by 3

Advances on potential therapeutic options for epidermolysis bullosa

Rosa, L. D., Koller, U., Bauer, J. W., Luca, M. D., & Reichelt, J. (2018) · Expert Opinion on Orphan Drugs · doi:10.1080/21678707.2018.1463216 · Cited by 4

Photoaffinity Ligand of Cystic Fibrosis Corrector VX-445 Identifies SCCPDH as an Off-Target

Kim, M., Kim, K., Lee, J., Barny, L. A., Scaggs, T. D., Romaine, I. M., Jeon, K., Codreanu, S. G., Sherrod, S. D., MCLEAN, J. A. J., et al. (2025) · ACS Chemical Biology · doi:10.1021/acschembio.5c00157 · Cited by 3

Human induced pluripotent stem cell–derived keratinocyte progenitors

Sah, S. K., Chen, I., & Reichenberger, E. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85545-7.00008-9 · Cited by 2

Pluripotent stem cells as a cellular model for skin: relevance for physiopathology, cell/gene therapy and drug screening

Levy, A., Petit, I., & Aberdam, D. (2015) · European Journal of Dermatology · doi:10.1684/ejd.2015.2537 · Cited by 2

Use of Stem Cells in Acute and Complex Wounds

Yousuf, Y., Amini‐Nik, S., & Jeschke, M. G. (2017) · Stem cells in clinical applications · doi:10.1007/978-3-319-55687-1_9 · Cited by 2

Noninvasive cancer detection by extracting and integrating multi-modal data from whole-methylome sequencing of plasma cell-free DNAPreprint

Bie, F., Wang, Z., Li, Y., Hong, Y., Han, T., Lv, F., Yang, S., Li, S., Li, X., Nie, P., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.04.498641 · Cited by 1

Cell Therapy and the Skin: Great Potential but in Need of Optimization

Lee, S. S., Peña, E. G. M., Willis, A. A., Wang, C. C., Haddad, N. R., & Garza, L. A. (2024) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.09.011 · Cited by 1

YAP-TEAD regulates the super-enhancer network to control early surface ectoderm commitment

Wang, Z., Yang, C., Ma, Z., He, X., Li, L., Wang, Y., Wang, Y., Cai, X., Jiao, H., Zhang, M., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1285 · Cited by 1

Stem Cells for the Regeneration of Chronic Wounds

Estronca, L. M. B. B., & Ferreira, L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-444-63265-4.00013-3 · Cited by 1

Cells and Structures Involved in Hair Follicle Regeneration: An Introduction

Tsai, J., & Garza, L. A. (2022) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-030-98331-4_3 · Cited by 1

Scaling Autologous Epidermal Cell Therapies: iPSC ‐Derived Keratinocytes and In Vivo Chimerism for Skin Regeneration

Kardeh, S., Mazloomrezaei, M., & Hosseini, A. (2025) · Experimental Dermatology · doi:10.1111/exd.70107 · Cited by 2

Forschung zu Genodermatosen durch neue Genom‐Editing‐Methoden

Lehmann, J., Seebode, C., & Emmert, S. (2017) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/ddg.13270_g · Cited by 1

Organotypic and humanized animal models of genodermatoses

Chacón-Solano, E., Guerrero‐Aspizua, S., Martínez‐Santamaría, L., Río, M. D., & Larcher, F. (2018) · Academic Press eBooks · doi:10.1016/b978-0-12-810545-0.00004-8 · Cited by 1

Milieu-Initiated Inversion of the Aqueous Polyproline II/β Propensity in the Alanine Tripeptide: Aggregation Origin of the Onset of Amyloid Formation

Mirkin, N. G., & Krimm, S. (2018) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.8b00612 · Cited by 1

Cell Therapies: New Frontier for the Management of Diabetic Foot Ulceration

Kashpur, O., Smith, A., Imbriaco, R., Greaves, B., Gerami‐Naini, B., & Garlick, J. A. (2018) · Contemporary diabetes · doi:10.1007/978-3-319-89869-8_13 · Cited by 1

Promotion of Wound Repair Using Stem Cell Therapies

Kosaric, N., & Gurtner, G. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65452-1 · Cited by 1

Stem Cell Therapy

Graffmann, N., Spitzhorn, L., Martins, S., Rahman, M. S., Nguyen, L., & Adjaye, J. (2019) · Springer eBooks · doi:10.1007/978-3-319-56637-5_72-1 · Cited by 1

Commentary: New advances in the development of therapies for treating inherited skin fragility disorders

Kopecki, Z., & Cowin, A. J. (2015) · Wound Practice & Research: Journal of the Australian Wound Management Association · Cited by 1

Feedback Regulation between Initiation and Maturation Networks Orchestrates the Chromatin Dynamics of Epidermal Lineage CommitmentPreprint

Li, L., Wang, Y., Torkelson, J. L., Shankar, G., Pattison, J. M., Zhen, H. H., Duren, Z., Fang, F., Melo, S. P., Piekos, S. N., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/349308 · Cited by 1

Naming Human Diseases: Ethical Principles of Curating Exclusive Substitute for Inopportune NosologyPreprint

Zhi, H., Ya, C., Song, Y., Yang, Z., & Huang, H. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.05.01.442270 · Cited by 1

Growth retardation in a mouse model of Kabuki syndrome 2 bears mechanistic similarities to Kabuki syndrome 1Preprint

Gao, C. W., Lin, W., Riddle, R. C., Chopra, S., Boukas, L., Hansen, K. D., Bjornsson, H. T., & Fahrner, J. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.15.562327 · Cited by 1

Innate immune system signaling and CD11b + CD11c + CD103 + cell migration to the brain underlie changes in mouse behavior after microbial colonizationPreprint

Philip, V., Kraïmi, N., Zhang, H., Lü, J., Palma, G. D., Shimbori, C., McCoy, K. D., Hapfelmeier, S., Schären, O. P., Macpherson, A. J., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.03.600853 · Cited by 1

Direct Prosthesis Force Control with Tactile Feedback May Connect with the Internal ModelPreprint

Chowdhury, N. H., Schramfield, S., Pariseau, P., & Tyler, D. J. (2024) · medRxiv · doi:10.1101/2024.12.05.24318338 · Cited by 1

Induced Pluripotent Stem Cells from Individuals with Recessive Dystrophic Epidermolysis Bullosa

Tolar, J., Xia, L., Riddle, M. J., Lees, C. J., Eide, C. R., McElmurry, R. T., Titeux, M., Osborn, M. J., Lund, T. C., Hovnanian, A., et al. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.346 · Cited by 155

Genetically corrected iPSCs as cell therapy for recessive dystrophic epidermolysis bullosa

Wenzel, D., Bayerl, J., Nyström, A., Bruckner-Tuderman, L., Meixner, A., & Penninger, J. M. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3010083 · Cited by 62

Induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa.

Spiliοpoulos, S., & Davanos, N. (2015) · PubMed Central · doi:10.3978/j.issn.2305-5839.2015.09.42 · Cited by 4

289 CRISPR/Cas9 and Homology Directed Repair-mediated correction of COL7A1 recurrent mutations in induced pluripotent stem cells from patients with recessive dystrophic epidermolysis bullosa

Izmiryan, A., Berthault, C., & Hovnanian, A. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.07.290

371 CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa (RDEB)

Osborn, M. J., Webber, B. R., McElroy, A. N., DeFeo, A. P., Patel, D., Lees, C. J., McElmurry, R. T., Riddle, M. J., Blazar, B. R., & Tolar, J. (2016) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.02.404