A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

MicroRNA targets in Drosophila

Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597

Transient Regenerative Potential of the Neonatal Mouse Heart

Porrello, E. R., Mahmoud, A. I., Simpson, E., Hill, J. A., Richardson, J. A., Olson, E. N., & Sadek, H. A. (2011) · Science · doi:10.1126/science.1200708 · Cited by 2,545

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

Chi, S. W., Zang, J. B., Mele, A., & Darnell, R. B. (2009) · Nature · doi:10.1038/nature08170 · Cited by 1,791

Mammalian heart renewal by pre-existing cardiomyocytes

Senyo, S. E., Steinhauser, M. L., Pizzimenti, C. L., Yang, V. K., Cai, L., Wang, M., Wu, T.-D., Guerquin-Kern, J.-L., Lechene, C. P., & Lee, R. T. (2013) · Nature · doi:10.1038/nature11682 · Cited by 1,343

Heart regeneration

Laflamme, M. A., & Murry, C. E. (2011) · Nature · doi:10.1038/nature10147 · Cited by 1,272

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

Anokye‐Danso, F., Trivedi, C. M., Juhr, D., Gupta, M., Cui, Z., Tian, Y., Zhang, Y., Yang, W., Gruber, P. J., Epstein, J. A., et al. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.03.001 · Cited by 1,244

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

Heallen, T. R., Zhang, M., Wang, J., Bonilla-Claudio, M., Klysik, E., Johnson, R. L., & Martin, J. F. (2011) · Science · doi:10.1126/science.1199010 · Cited by 1,092

Functional screening identifies miRNAs inducing cardiac regeneration

Eulalio, A., Mano, M., Ferro, M. D., Zentilin, L., Sinagra, G., Zacchigna, S., & Giacca, M. (2012) · Nature · doi:10.1038/nature11739 · Cited by 1,029

A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout MutationsPreprint

Liu, P., Jenkins, N. A., & Copeland, N. G. (2003) · Genome Research · doi:10.1101/gr.749203 · Cited by 1,013

Comprehensive circRNA expression profile and construction of circRNA-related ceRNA network in cardiac fibrosis

Gu, X., Jiang, Y., Wang, W., Zhang, J., Shang, D., Sun, C., Tian, J.-T., Tian, J., Yu, B., & Zhang, Y. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.109944 · Cited by 40

Cardiac Regeneration: New Hope for an Old Dream

Weinberger, F., & Eschenhagen, T. (2020) · Annual Review of Physiology · doi:10.1146/annurev-physiol-031120-103629 · Cited by 39

Stem cell therapy for acute myocardial infarction: Mesenchymal Stem Cells and induced Pluripotent Stem Cells

Clavellina, D., Balkan, W., & Hare, J. M. (2023) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2023.2245329 · Cited by 40

Therapeutic targeting of autophagy in myocardial infarction and heart failure

Riquelme, J. A., Chávez, M. N., Mondaca‐Ruff, D., Bustamante, M., Vicencio, J. M., Quest, A. F. G., & Lavandero, S. (2016) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2016.1202760 · Cited by 37

Gene Therapy for Heart Failure: New Perspectives

Gabisonia, K., & Recchia, F. A. (2018) · Current Heart Failure Reports · doi:10.1007/s11897-018-0410-z · Cited by 36

Adult Cardiomyocyte Proliferation: a New Insight for Myocardial Infarction Therapy

Zhu, F., Meng, Q., You, Y., Shao, L., & Shen, Z. (2020) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-020-10067-8 · Cited by 39

Cell-Based and Selected Cell-Free Therapies for Myocardial Infarction: How Do They Compare to the Current Treatment Options?

Csöbönyeiová, M., Beerová, N., Klein, M., Čeháková, M., & Danišovič, Ľ. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810314 · Cited by 38

Isolation, Culture and Transduction of Adult Mouse Cardiomyocytes

Judd, J., Lovas, J., & Huang, G. N. (2016) · Journal of Visualized Experiments · doi:10.3791/54012 · Cited by 38

How Hippo Signaling Pathway Modulates Cardiovascular Development and Diseases

Zhou, W., & Zhao, M. (2018) · Journal of Immunology Research · doi:10.1155/2018/3696914 · Cited by 36

Mechanisms of Neonatal Heart Regeneration

Cardoso, A. C., Pereira, A. H. M., & Sadek, H. A. (2020) · Current Cardiology Reports · doi:10.1007/s11886-020-01282-5 · Cited by 39

Non-coding RNAs in Cardiac Regeneration

Yuan, T., & Krishnan, J. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.650566 · Cited by 35

Reawakening the Intrinsic Cardiac Regenerative Potential: Molecular Strategies to Boost Dedifferentiation and Proliferation of Endogenous Cardiomyocytes

Bongiovanni, C., Sacchi, F., Pra, S. D., Pantano, E., Miano, C., Morelli, M. B., & D’Uva, G. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.750604 · Cited by 36

Regulation of endogenous cardiomyocyte proliferation: The known unknowns

Secco, I., & Giacca, M. (2023) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2023.04.001 · Cited by 35

miR-301a-PTEN-AKT Signaling Induces Cardiomyocyte Proliferation and Promotes Cardiac Repair Post-MI

Zhen, L., Zhao, Q., Lü, J., Deng, S., Xu, Z., Zhang, L., Zhang, Y., Fan, H., Chen, X., Liu, Z., et al. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2020.08.033 · Cited by 35

A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration

Raso, A., Dirkx, E., Sampaio‐Pinto, V., el Azzouzi, H., Cubero, R. J., Sorensen, D. W., Ottaviani, L., Olieslagers, S., Huibers, M. M. H., de Weger, R. A., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25211-4 · Cited by 37

The MicroRNA

Ying, S., Chang, D. C., & Lin, S.-L. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7601-0_1 · Cited by 36

Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges

Bernardo, B. C., Gregorevic, P., Ritchie, R. H., & McMullen, J. R. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01090 · Cited by 38

Insight into Heart-Tailored Architectures of Hydrogel to Restore Cardiac Functions after Myocardial Infarction

Chen, X., Zhu, L., Wang, X., & Xiao, J. (2022) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.2c00650 · Cited by 34

The regulation and function of the Hippo pathway in heart regeneration

Liu, S., & Martin, J. F. (2018) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.335 · Cited by 34

Regenerative therapy based on miRNA-302 mimics for enhancing host recovery from pneumonia caused by Streptococcus pneumoniae

Wang, Y., Li, Y., Zhang, P., Baker, S. T., Wolfson, M. R., Weiser, J. N., Tian, Y., & Shen, H. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1818522116 · Cited by 33

The Role of Reactive Oxygen Species in In Vitro Cardiac Maturation

Momtahan, N., Crosby, C. O., & Zoldan, J. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2019.04.005 · Cited by 33

IGF2BP3 promotes adult myocardial regeneration by stabilizing MMP3 mRNA through interaction with m6A modification

Li, S., Shen, S., Xu, H., Cai, S., Yuan, X., Wang, C., Zhang, X., Chen, S., Chen, J., Shi, D., et al. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01457-3 · Cited by 31

A comprehensive, multiscale framework for evaluation of arrhythmias arising from cell therapy in the whole post-myocardial infarcted heart

Yu, J. K., Franceschi, W. H., Huang, Q., Pashakhanloo, F., Boyle, P. M., & Trayanova, N. A. (2019) · Scientific Reports · doi:10.1038/s41598-019-45684-0 · Cited by 32

Heart regeneration

Breckwoldt, K., Weinberger, F., & Eschenhagen, T. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.11.010 · Cited by 31

MicroRNA‐302c‐3p inhibits endothelial cell pyroptosis via directly targeting NOD‐, LRR‐ and pyrin domain‐containing protein 3 in atherosclerosis

Bai, B., Yang, Y., Ji, S., Wang, S., Peng, X., Tian, C., Sun, R., Yu, T., & Chu, X. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16500 · Cited by 31

A Hearty Dose of Noncoding RNAs: The Imprinted DLK1-DIO3 Locus in Cardiac Development and Disease

Dill, T. L., & Naya, F. J. (2018) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd5030037 · Cited by 31

Possible Muscle Repair in the Human Cardiovascular System

Sommese, L., Zullo, A., Schiano, C., Mancini, F. P., & Claudio Napoli, A. (2017) · Stem Cell Reviews and Reports · doi:10.1007/s12015-016-9711-3 · Cited by 30

Inhibition of miR‐302 Suppresses Hypoxia‐Reoxygenation‐Induced H9c2 Cardiomyocyte Death by Regulating Mcl‐1 Expression

Fang, Y.-C., & Yeh, C. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/7968905 · Cited by 31

MicroRNA-302d promotes the proliferation of human pluripotent stem cell-derived cardiomyocytes by inhibiting LATS2 in the Hippo pathway

Xu, F., Yang, J., Shang, J., Lan, F., Li, M., Shi, L. M., Shen, L., Wang, Y., & Ge, J. (2019) · Clinical Science · doi:10.1042/cs20190099 · Cited by 30

miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7

Wang, B., Xu, M., Li, M., Wu, F., Hu, S., Chen, X., Zhao, L., Huang, Z., Lan, F., Liu, D., et al. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2020.01.013 · Cited by 30

Mending a Faltering Heart

Li, M., & Belmonte, J. C. I. (2016) · Circulation Research · doi:10.1161/circresaha.115.306820 · Cited by 29

Oxidized low‐density lipoprotein promotes vascular endothelial cell dysfunction by stimulating miR‐496 expression and inhibiting the Hippo pathway effector YAP

Hu, J., Liu, T., Zhang, Z., Xu, Y., & Zhu, F. (2019) · Cell Biology International · doi:10.1002/cbin.11120 · Cited by 29

MicroRNA302-367-PI3K-PTEN-AKT-mTORC1 pathway promotes the development of cardiac hypertrophy through controlling autophagy

Jin, L., Zhou, Y., Han, L., & Piao, J. (2019) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-019-00417-5 · Cited by 30

Cardiomyocyte Proliferation as a Source of New Myocyte Development in the Adult Heart

Johnson, J. P., Mohsin, S., & Houser, S. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157764 · Cited by 31

State of the Art and Perspectives of Gene Therapy in Heart Failure. A Scientific Statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial & Pericardial Diseases

Linthout, S. V., Stellos, K., Giacca, M., Bertero, E., Cannata, A. N., Carrier, L., García‐Pavía, P., Ghigo, A., González, A., Haugaa, K. H., et al. (2024) · European Journal of Heart Failure · doi:10.1002/ejhf.3516 · Cited by 29

Circulating miRNA-302 Family Members as Potential Biomarkers for the Diagnosis of Acute Heart Failure

Li, G., Song, Y., Li, Y., Jie, L., Wu, W., Li, J.-Z., Zhang, Q., & Wang, Y. (2018) · Biomarkers in Medicine · doi:10.2217/bmm-2018-0132 · Cited by 28

Non-coding RNAs in cardiac regeneration: Mechanism of action and therapeutic potential

Wang, Y., Chen, J., Cowan, D. B., & Wang, D. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.07.007 · Cited by 28

Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01722-7 · Cited by 30

Sustained cardiac programming by short‐term juvenile exercise training in male rats

Yusuf, A., Wlodek, M. E., Black, M. J., Russell, A. P., Soeding, P., & Wadley, G. D. (2017) · The Journal of Physiology · doi:10.1113/jp275339 · Cited by 27

Combining Nanomaterials and Developmental Pathways to Design New Treatments for Cardiac Regeneration: The Pulsing Heart of Advanced Therapies

Cassani, M., Fernandes, S., Vrbský, J., Ergir, E., Cavalieri, F., & Forte, G. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00323 · Cited by 29

Bioderived Nanoparticles for Cardiac Repair

Cui, X., Guo, J., Yuan, P., Dai, Y., Du, P., Yu, F., Sun, Z., Zhang, J., Cheng, K., & Tang, J. (2024) · ACS Nano · doi:10.1021/acsnano.3c07878 · Cited by 27

MircroRNA-10b Promotes Human Embryonic Stem Cell-Derived Cardiomyocyte Proliferation via Novel Target Gene LATS1

Xie, Y., Wang, Q., Gao, N., Wu, F., Lan, F., Zhang, F., Li, J., Huang, Z., Ge, J., Wang, H., et al. (2019) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2019.11.026 · Cited by 25

Efficient and precise delivery of microRNA by photoacoustic force generated from semiconducting polymer-based nanocarriers

Kang, T., Ni, J., Li, T., Wang, J., Li, Z., Li, Y., Zha, M., Zhang, C., Wu, X., Guo, H., et al. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120907 · Cited by 25

MICU1-dependent mitochondrial calcium uptake regulates lung alveolar type 2 cell plasticity and lung regeneration

Ali, M., Zhang, X., LaCanna, R., Tomar, D., Elrod, J. W., & Tian, Y. (2022) · JCI Insight · doi:10.1172/jci.insight.154447 · Cited by 23

Cardiac regeneration – Past advancements, current challenges, and future directions

Pezhouman, A., Nguyen, N. B., Kay, M., Kanjilal, B., Noshadi, I., & Ardehali, R. (2023) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2023.07.009 · Cited by 27

Harnessing the Induction of Cardiomyocyte Proliferation for Cardiac Regenerative Medicine

Sharma, A., Zhang, Y., & Wu, S. M. (2015) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-015-0404-z · Cited by 25

Direct Cellular Reprogramming for Cardiac Repair and Regeneration

Batty, J. A., Lima, J. A. C., & Kunadian, V. (2015) · European Journal of Heart Failure · doi:10.1002/ejhf.446 · Cited by 25

Neonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration

Costa, A., Cushman, S., Haubner, B. J., Derda, A. A., Thum, T., & Bär, C. (2022) · Basic Research in Cardiology · doi:10.1007/s00395-022-00931-w · Cited by 26

A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration

Alharbi, K. S., Almalki, W. H., Alzarea, S. I., Kazmi, I. A., Al-Abbasi, F. A., Afzal, O., Altamimi, A. S. A., Singh, S. K., Dua, K., & Gupta, G. (2022) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2022.110011 · Cited by 24

Cardiac regeneration: Options for repairing the injured heart

Wang, J., An, M., Haubner, B. J., & Penninger, J. M. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.981982 · Cited by 26

Pioneering therapies for post-infarction angiogenesis: Insight into molecular mechanisms and preclinical studies

Chen, C., Wang, J., Liu, C., Hu, J., & Liu, L. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115306 · Cited by 25

New Trends in Heart Regeneration: A Review

Kochegarov, A., & Lemanski, L. F. (2016) · Journal of Stem Cells and Regenerative Medicine · doi:10.46582/jsrm.1202010 · Cited by 24

Application of Cell, Tissue, and Biomaterial Delivery in Cardiac Regenerative Therapy

Portillo‐Esquivel, L. E., & Zhang, B. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c01805 · Cited by 22

Induced Cardiomyocyte Proliferation: A Promising Approach to Cure Heart Failure

Salama, A. B. M., Gebreil, A., Mohamed, T., & Abouleisa, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147720 · Cited by 23

Transcriptional Co-Activators YAP1–TAZ of Hippo Signalling in Doxorubicin-Induced Cardiomyopathy

Berecz, T., Yiu, A., Vittay, O. I., Orsolits, B., Mioulane, M., dos Remedios, C. G., Ketteler, R., Merkely, B. P., Apáti, Á., Harding, S. E., et al. (2021) · ESC Heart Failure · doi:10.1002/ehf2.13756 · Cited by 22

Translational aspects of cardiac cell therapy

Chen, C., Sereti, K., Wu, B. M., & Ardehali, R. (2015) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12632 · Cited by 23

Elevated Expression of miR302-367 in Endothelial Cells Inhibits Developmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways

Pi, J., Liu, J., Zhuang, T., Zhang, L., Sun, H., Chen, X., Zhao, Q., Kuang, Y., Peng, S., Zhou, X., et al. (2018) · Theranostics · doi:10.7150/thno.21986 · Cited by 23

Noncoding RNAs regulating cardiac muscle mass

Wadley, G. D., Lamon, S., Alexander, S. E., McMullen, J. R., & Bernardo, B. C. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00904.2018 · Cited by 23

Reviewing the Limitations of Adult Mammalian Cardiac Regeneration: Noncoding RNAs as Regulators of Cardiomyogenesis

Verjans, R., van Bilsen, M., & Schroen, B. L. M. (2020) · Biomolecules · doi:10.3390/biom10020262 · Cited by 24

Role of miR-302/367 cluster in human physiology and pathophysiology

Guo, M., Gan, L., Si, J., Zhang, J., Liu, Z., Zhao, J., Gou, Z., & Zhang, H. (2020) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmaa065 · Cited by 23

Hippo vs. Crab: tissue‐specific functions of the mammalian Hippo pathway

Nishio, M., Maehama, T., Goto, H., Nakatani, K., Kato, W., Omori, H., Miyachi, Y., Togashi, H., Shimono, Y., & Suzuki, A. (2017) · Genes to Cells · doi:10.1111/gtc.12461 · Cited by 22

A DGCR8-Independent Stable MicroRNA Expression Strategy Reveals Important Functions of miR-290 and miR-183–182 Families in Mouse Embryonic Stem Cells

Wang, X., Hao, J., Guo, W., Liao, L., Huang, S.-Y., Guo, X., Bao, X., Esteban, M. A., & Wang, Y. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.08.027 · Cited by 22

Cardiomyocyte maturation and its reversal during cardiac regeneration

Beisaw, A., & Wu, C. C. (2022) · Developmental Dynamics · doi:10.1002/dvdy.557 · Cited by 21

Nanoparticle–Patch System for Localized, Effective, and Sustained miRNA Administration into Infarcted Myocardium to Alleviate Myocardial Ischemia–Reperfusion Injury

Chen, X., Chen, H., Zhu, L., Zeng, M., Wang, T., Su, C., Vulugundam, G., Gokulnath, P., Li, G., Wang, X., et al. (2024) · ACS Nano · doi:10.1021/acsnano.3c08811 · Cited by 21

MiR-138 protects cardiac cells against hypoxia through modulation of glucose metabolism by targetting pyruvate dehydrogenase kinase 1

Zhu, H., Xue, H., Jin, Q., Guo, J., & Chen, Y. (2017) · Bioscience Reports · doi:10.1042/bsr20170296 · Cited by 21

Delta-1 Functionalized Hydrogel Promotes hESC-Cardiomyocyte Graft Proliferation and Maintains Heart Function Post-Injury

Gerbin, K. A., Mitzelfelt, K. A., Guan, X., Martinson, A., & Murry, C. E. (2020) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2020.04.011 · Cited by 21

The Regulation Mechanisms and Clinical Application of MicroRNAs in Myocardial Infarction: A Review of the Recent 5 Years

Wu, C., Liu, B., Wang, R., & Li, G. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.809580 · Cited by 21

G1/S restriction point coordinates phasic gene expression and cell differentiation

DeVeale, B., Liu, L., Boileau, R. M., Swindlehurst-Chan, J., Marsh, B., Freimer, J. W., Abate, A. R., & Blelloch, R. H. (2022) · Nature Communications · doi:10.1038/s41467-022-31101-0 · Cited by 20

RNA therapeutics for heart disease

Majo, F. D., & Windt, L. J. D. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.07.037 · Cited by 20

Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes

Judd, J., Lovas, J., & Huang, G. N. (2019) · Scientific Reports · doi:10.1038/s41598-019-55027-8 · Cited by 20

State-Of-Play for Cellular Therapies in Cardiac Repair and Regeneration

Vaka, V. R., & Davis, D. R. (2021) · Stem Cells · doi:10.1002/stem.3446 · Cited by 21

Harnessing Mechanosensation in Next Generation Cardiovascular Tissue Engineering

Garoffolo, G., Ferrari, S., Rizzi, S., Barbuto, M., Bernava, G., & Pesce, M. (2020) · Biomolecules · doi:10.3390/biom10101419 · Cited by 18

Yes-Associated Protein and Transcriptional Coactivator with PDZ-Binding Motif in Cardiovascular Diseases

Li, R., & Huang, W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021666 · Cited by 19

Fluorescent conjugated polymer nanovector for in vivo tracking and regulating the fate of stem cells for restoring infarcted myocardium

Jin, G., Li, W., Song, F., Zhao, J., Wang, M., Liu, Q., Li, A., Huang, G., & Xu, F. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.04.010 · Cited by 19

mir15a/mir16‐1 cluster and its novel targeting molecules negatively regulate cardiac hypertrophy

Guo, H., Ma, K., Hao, W., Yao, J., Li, Y., Chen, J., Chen, X., Xu, F., Lau, W. B., Du, J., et al. (2020) · Clinical and Translational Medicine · doi:10.1002/ctm2.242 · Cited by 17

Molecular regulation of myocardial proliferation and regeneration

Zheng, L., Du, J., Wang, Z., Zhou, Q., Zhu, X., & Xiong, J. (2021) · Cell Regeneration · doi:10.1186/s13619-021-00075-7 · Cited by 18

The regenerative capacity of neonatal tissues

Montero, A. M., & Huang, A. H. (2022) · Development · doi:10.1242/dev.199819 · Cited by 19

Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice

Nugroho, A. B., Stafford, N., Zi, M., Prehar, S., Potter, R., Kwon, D., Kohar, Y. S., Triastuti, E., Bùi, T. A., Cartwright, E. J., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.05.008 · Cited by 19

Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration

Wang, Q., Song, Y., Gao, J., Li, Q., Chen, J., Xie, Y., Wang, Z., Tan, H., Yang, H., Zhang, N., et al. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2023.08.021 · Cited by 18

Stem cell-derived exosome delivery systems for treating atherosclerosis: The new frontier of stem cell therapy

Tariq, H., Bukhari, S. Z., An, R., Dong, J., Ihsan, A., & Younis, M. R. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101440 · Cited by 18

Cardiac regeneration: All work and no repair?

Kennedy‐Lydon, T., & Rosenthal, N. A. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aad9019 · Cited by 18

The Emerging Link between the Hippo Pathway and Non-coding RNA

Shimoda, M., & Moroishi, T. (2019) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b19-00795 · Cited by 16

Transposon control as a checkpoint for tissue regeneration

Angileri, K. M., Bagia, N. A., & Feschotte, C. (2022) · Development · doi:10.1242/dev.191957 · Cited by 15

The miR‐17‐92 cluster in cardiac health and disease

Cao, Y., Zheng, M., Sewani, M. A., & Wang, J. (2023) · Birth Defects Research · doi:10.1002/bdr2.2273 · Cited by 17

The roles of non-coding RNAs in cardiac regenerative medicine

Choong, O. K., Lee, D. S., Chen, C.-Y., & Hsieh, P. C. H. (2017) · Non-coding RNA Research · doi:10.1016/j.ncrna.2017.06.001 · Cited by 17

Implications of scar structure and mechanics for post-infarction cardiac repair and regeneration

French, B. A., & Holmes, J. W. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.01.001 · Cited by 18

MiRNAs: A Powerful Tool in Deciphering Gynecological Malignancies

Duică, F., Condrat, C. E., Dănilă, C. A., Boboc, A. E., Radu, M. R., Xiao, J., Li, X., Creţoiu, S. M., Suciu, N., Crețoiu, D., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.591181 · Cited by 17

miR‑449a‑5p suppresses CDK6 expression to inhibit cardiomyocyte proliferation

Li, B., Zhi, W., Yang, F., Huang, J., Hu, X., Deng, S., Tian, M., & Si, X. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11652 · Cited by 17

Differential Regulation of mTOR Complexes with miR-302a Attenuates Myocardial Reperfusion Injury in Diabetes

Samidurai, A., Ockaili, R. A., Cain, C. K., Roh, S. K., Filippone, S. M., Kraskauskas, D., Kukreja, R. C., & Das, A. (2020) · iScience · doi:10.1016/j.isci.2020.101863 · Cited by 18

METTL14-mediated m6A methylation of pri-miR-5099 to facilitate cardiomyocyte pyroptosis in myocardial infarction

Yu, H., Li, Q.-S., Guo, J., Zhang, Z., Lang, X.-Z., Liu, Y., Qin, L., Xu, S., Zhang, Q., Xue, Y.-D., et al. (2025) · Acta Pharmacologica Sinica · doi:10.1038/s41401-025-01485-y · Cited by 16

RNA interference therapeutics for cardiac regeneration

Huntington, J., Pachauri, M., Ali, H., & Giacca, M. (2021) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2021.05.007 · Cited by 17

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Sacco, A., Martelli, F., Pal, A., Saraceno, C., Benussi, L., Ghidoni, R., Rongioletti, M. C. A., & Squitti, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063327 · Cited by 16

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Windmueller, R., & Morrisey, E. E. (2015) · Circulation Research · doi:10.1161/circresaha.115.307546 · Cited by 16

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Bernardo, B. C., & Blaxall, B. C. (2016) · Heart Lung and Circulation · doi:10.1016/j.hlc.2016.01.002 · Cited by 15

Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes

Yasutake, H., Lee, J., Hashimoto, A., Masuyama, K., Li, J., Kuramoto, Y., Higo, S., Hikoso, S., Hidaka, K., Naito, A. T., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-89603-8 · Cited by 16

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Elia, A., Mohsin, S., & Khan, M. (2023) · Cells · doi:10.3390/cells12121571 · Cited by 15

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Giacca, M. (2023) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szad038 · Cited by 15

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Hassanabad, A. F., Zarzycki, A. N., & Fedak, P. W. M. (2024) · Cardiovascular Pathology · doi:10.1016/j.carpath.2024.107635 · Cited by 18

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Chen, E. Y. Y., Chen, J. S., & Ying, S. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e01167 · Cited by 14

Integrated Perspective of Scaffold Designing and Multiscale Mechanics in Cardiac Bioengineering

Lou, L., Orikasa, K., Nautiyal, P., & Agarwal, A. K. (2021) · Advanced NanoBiomed Research · doi:10.1002/anbr.202100075 · Cited by 13

Abstract 259: A Microrna Pathway That Promotes Cardiomyocyte Proliferation And Cardiac Regeneration By Inhibiting Hippo Signaling

Tian, Y., Chen, L., Wang, T., Zhou, N., Kong, J., Liu, Y., Snitow, M. E., Morley, M. P., Li, D., Petrenko, N. B., et al. (2014) · Circulation Research · doi:10.1161/res.115.suppl_1.259

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Nugroho, A. B., Stafford, N., Zi, M., Prehar, S., Potter, R., Kwon, D., Kohar, Y. S., Triastuti, E., Bùi, T. A., Cartwright, E. J., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.05.008 · Cited by 19

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Ouyang, Z., & Wei, K. (2021) · Cell Regeneration · doi:10.1186/s13619-021-00077-5 · Cited by 77

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Giacca, M. (2015) · Molecular Therapy · doi:10.1038/mt.2015.86

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Zhen, L., Zhao, Q., Lü, J., Deng, S., Xu, Z., Zhang, L., Zhang, Y., Fan, H., Chen, X., Liu, Z., et al. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2020.08.033 · Cited by 35