A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

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The Noncoding Side of Cardiac Differentiation and Regeneration

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Therapeutic Acellular Scaffolds for Limiting Left Ventricular Remodelling-Current Status and Future Directions

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Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation

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Spotlight on epigenetic reprogramming in cardiac regeneration

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Targeting cardiomyocyte proliferation as a key approach of promoting heart repair after injury

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Streptococcus gordonii Supragingival Bacterium Oral Infection-Induced Periodontitis and Robust miRNA Expression Kinetics

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LncRNAs in Cardiomyocyte Maturation: New Window for Cardiac Regenerative Medicine

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Defining the molecular underpinnings controlling cardiomyocyte proliferation

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Epigenetic Modification Factors and microRNAs Network Associated with Differentiation of Embryonic Stem Cells and Induced Pluripotent Stem Cells toward Cardiomyocytes: A Review

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Exosomes as intercellular communication messengers for cardiovascular and cerebrovascular diseases

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The emerging role of miRNAs in myocardial infarction: From molecular signatures to therapeutic targets

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Pharmacokinetics and cardioprotective efficacy of intravenous miR‐125b* microRNA mimic in a mouse model of acute myocardial infarction

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Endogenous Mechanisms of Cardiac Regeneration

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Gene transfer to promote cardiac regeneration

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Pentoxifylline alleviated cardiac injury via modulating the cardiac expression of lncRNA-00654-miR-133a-SOX5 mRNA in the rat model of ischemia-reperfusion

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Neuregulin-1 enhances cell-cycle activity, delays cardiac fibrosis, and improves cardiac performance in rat pups with right ventricular pressure load

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Manipulating Cardiomyocyte Plasticity for Heart Regeneration

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Endothelial plasticity across PTEN and Hippo pathways: A complex hormetic rheostat modulated by extracellular vesicles

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Effects and mechanisms of the myocardial microenvironment on cardiomyocyte proliferation and regeneration

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Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15

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Hippo signaling and histone methylation control cardiomyocyte cell cycle re-entry through distinct transcriptional pathways

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Revolutionizing cardiovascular research: Human organoids as a Beacon of hope for understanding and treating cardiovascular diseases

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Delayed miR-199a Administration After Myocardial Infarction Precludes Pro-Regenerative Effects

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Innate heart regeneration: endogenous cellular sources and exogenous therapeutic amplification

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Cardiac regenerative medicine: At the crossroad of microRNA function and biotechnology

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Non-Coding RNAs in Stem Cell Regulation and Cardiac Regeneration: Current Problems and Future Perspectives

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The cell-autonomous and non–cell-autonomous roles of the Hippo pathway in heart regeneration

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Gene Therapy for Cardiomyocyte Renewal: Cell Cycle, a Potential Therapeutic Target

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Targeting the Cardiomyocyte Cell Cycle for Heart Regeneration

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A miRNA’s insight into the regenerating heart: a concise descriptive analysis

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Photosynthetic symbiotic therapeutics – An innovative, effective treatment for ischemic cardiovascular diseases

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Restoring Ravaged Heart: Molecular Mechanisms and Clinical Application of miRNA in Heart Regeneration

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The Role of the Autonomic Nervous System in Cardiovascular Toxicity

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The emerging therapeutic role of mesenchymal stem cells in anthracycline-induced cardiotoxicity

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Cell Reprogramming, Transdifferentiation, and Dedifferentiation Approaches for Heart Repair

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Mitigation of Doxorubicin Cardiotoxicity With Synergistic miRNA Combinations Identified Using Combinatorial Genetics en masse (CombiGEM)

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Nanodrug targeting for myocardial ischemia-reperfusion injury: mechanisms, therapeutic strategies, and challenges in clinical translation

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Remodeling of non-coding RNA regulatory networks: Decoding the pathological mechanisms and new therapeutic paradigms of cardiovascular diseases

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Non-coding RNAs in Cardiac Regeneration

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Reactive Oxygen Species-Mediated Diabetic Heart Disease: Mechanisms and Therapies

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Contemporary Challenges of Regenerative Therapy in Patients with Ischemic and Non-Ischemic Heart Failure

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Large-scale microRNA functional high-throughput screening identifies miR-515-3p and miR-519e-3p as inducers of human cardiomyocyte proliferation

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LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

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Idiopathic Pulmonary Arterial Hypertension: Network-Based Integration of Multi-Omics Data Reveals New Molecular Signatures and Candidate Drugs

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Delivery of SAV-siRNA via Exosomes from Adipose-Derived Stem Cells for the Treatment of Myocardial Infarction

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Integrated small RNA, mRNA and protein omics reveal a miRNA network orchestrating metabolic maturation of the developing human heart

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Emerging Roles for Immune Cells and MicroRNAs in Modulating the Response to Cardiac Injury

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Differential Spatio-Temporal Regulation of T-Box Gene Expression by microRNAs during Cardiac Development

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Micro RNAs: an arguable appraisal in medicine

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Noncoding RNA and Cardiomyocyte Proliferation

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MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging

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Time-regulated transcripts with the potential to modulate human pluripotent stem cell-derived cardiomyocyte differentiation

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Small RNA: From development to regeneration

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Myocardial regeneration therapy in heart failure: Current status and future therapeutic implications in clinical practice

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Research progress on myocardial regeneration: what is new?

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AntimiR-34a to Enhance Cardiac Repair After Ischemic Injury

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Approaches Toward Targeting Matrix Metalloproteases for Prognosis and Therapies in Gynecological Cancer: MicroRNAs as a Molecular Driver

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Stimulation of autologous progenitorial and committed cells in ischemically damaged myocardium

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The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

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Circulating exosomal miR-550a-5p/miR-665 identify coronary microvascular dysfunction and drive endothelial–myocyte crosstalk in type 2 diabetes

Ding, X., Bai, G., Liu, X., Dong, Y., Chai, Y., Han, B., Meng, X., & Lei, H. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1744708 · Cited by 5

Natriuretic peptides and Forkhead O transcription factors act in a cooperative manner to promote cardiomyocyte cell cycle re-entry in the postnatal mouse heart

Ali, M. S., Liccardo, D., Cao, T., & Tian, Y. (2021) · BMC Developmental Biology · doi:10.1186/s12861-020-00236-y · Cited by 5

Analysis and Evaluation of Major COVID-19 Features: A Pairwise Comparison Approach

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Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing

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Endoplasmic reticulum and the microRNA environment in the cardiovascular system

Groenendyk, J., Fan, X., Peng, Z., Kurgan, L., & Michalak, M. (2019) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2018-0720 · Cited by 5

Activation or inhibition of PPARα-mediated fatty acid β-oxidation does not active cardiomyocyte proliferation in normal or infarcted adult micePreprint

Roy, R., Leigh, T., Gao, E., Zhang, X., & Tian, Y. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/667964 · Cited by 5

Non-coding RNAs as regulators of the Hippo pathway in cardiac development and cardiovascular disease

Song, M., Wang, H., Liu, C., Jin, S., Liu, B., & Sun, W. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1348280 · Cited by 7

Peripheral blood mesenchymal stem cell‐derived exosomes improve renal sympathetic denervation efficacy through β‐catenin‐mediated cardiac reprogramming

Zhao, L., Li, C., Huang, Z., Wang, J., Deng, Z., Deng, Y., Wang, P., & Zhang, S. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70475 · Cited by 4

Regulatory Mechanisms That Guide the Fetal to Postnatal Transition of Cardiomyocytes

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STEMIN and YAP5SA, the future of heart repair?

Bejar, N., Xiao, S., Iyer, D., Muili, A., Adeleye, A., McConnell, B. K., & Schwartz, R. J. (2024) · Experimental Biology and Medicine · doi:10.3389/ebm.2024.10246 · Cited by 4

Dynamic map illuminates Hippo-cMyc module crosstalk driving cardiomyocyte proliferation

Harris, B. N., Woo, L. A., Perry, R. N., Wallace, A., Civelek, M., Wolf, M. J., & Saucerman, J. J. (2025) · Development · doi:10.1242/dev.204397 · Cited by 4

The miR-290 and miR-302 clusters are essential for reprogramming of fibroblasts to induced pluripotent stem cells

Ye, J., Boileau, R. M., Parchem, R. J., Judson‐Torres, R. L., & Blelloch, R. H. (2025) · Stem Cells · doi:10.1093/stmcls/sxae080 · Cited by 4

Single dose of synthetic microRNA-199a or microRNA-149 mimic does not improve cardiac function in a murine model of myocardial infarction

Nong, Y., Guo, Y., Gumpert, A. M., Li, Q., Tomlin, A. A., Zhu, X., & Bolli, R. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04227-w · Cited by 4

Differential sensitivity to longitudinal and transverse stretch mediates transcriptional responses in mouse neonatal ventricular myocytes

Cao, S., Buchholz, K. S., Tan, P. M., Stowe, J. C., Wang, A., Fowler, A., Knaus, K. R., Khalilimeybodi, A., Zambon, A. C., Omens, J. H., et al. (2023) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00562.2023 · Cited by 4

Ephrin-B1 blocks adult cardiomyocyte proliferation and heart regenerationPreprint

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Long noncoding RNA LncBAR enhances BRG1 protein to promote cardiomyocyte cell cycle progression and cardiac repair

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