A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

MicroRNA targets in Drosophila

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Transient Regenerative Potential of the Neonatal Mouse Heart

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Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

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Functional screening identifies miRNAs inducing cardiac regeneration

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Mechanisms to Induce Cardiomyocyte Proliferation

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MicroRNAs in Cardiac Development and Function

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The Emerging Roles of LIS 1 Biomechanics in Cellular and Cortical Homeostasis

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Drug Discovery for Adult Cardiomyocyte Regeneration: Opportunities and Challenges

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Myocardial Tissue Repair and Regeneration

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Proregenerative MicroRNAs to Repair the Damaged Heart

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Decoding developmental signaling for heart regeneration

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Maternal Blood as a Window to the Fetal Heart: Novel Biomarkers for Early Detection of Septal Defects

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Cellular and molecular basis of cardiac regeneration

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Hippo signaling pathway regulation of innate immune response

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Genome Editing and Cardiac Regeneration

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MicroRNA Expression in the Infarcted Heart Following Neonatal Cardiovascular Progenitor Cell Transplantation in a Sheep Model of Stem Cell–Based Repair

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Hippo Pathway Knockdown Gene Therapy in the Heart

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Mechanism of Shenyuan Yiqi Huoxue capsule alleviating coronary microvascular dysfunction: network analysis and experimental evidence

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Noncoding RNAs in Ischemic Cardiovascular Disease and Repair Mechanisms

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Prospective Advances in Non-coding RNAs Investigation

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Mechanisms Underlying Cardiomyocyte Development: Can We Exploit Them to Regenerate the Heart?

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MiR-218 Promotes Adriamycin-Induced H9C2 Apoptosis by Inhibiting Stress-Associated Endoplasmic Reticulum Protein 1

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microRNA Modulation

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Combinatorial miRNA1a/15b interference drives adult cardiac regenerationPreprint

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Cellular Approaches to Adult Mammalian Heart Regeneration

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Gene and Cell Therapy in Heart Failure

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OBSOLETE: MicroRNAs in Cardiac Development and Function

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Uso de micro RNA en el manejo de la insuficiencia cardiaca

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OBSOLETE: Myocardial Repair

Eschenhagen, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99585-0

Advanced therapies to treat cardiovascular diseases: controversies and perspectives

Giacca, M., & Ibáñez, B. (2018) · doi:10.1093/med/9780198757269.003.0028

Recombinant Protein IGF1-24 Stimulates Rat Cardiomyocytes Proliferation and Repairs Myocardial InjuryPreprint

Wang, X., Fu, M., Qian, Y., Feng, J., Liao, Y., Xu, X., Chen, Y., Zhang, L., Sun, H., Liu, P., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.04.976522

Injectable biopolymers in the treatment of heart failure and cardiac remodeling

Wang, R. M., & Christman, K. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813706-2.00017-8

Factors affecting the proliferation of cardiomyocyte

Cao, X. (2020) · E3S Web of Conferences · doi:10.1051/e3sconf/202021803044

Endogenous Mechanisms for Cardiomyocyte Regeneration

Kartha, C. C. (2021) · Springer eBooks · doi:10.1007/978-3-030-85536-9_16

Faculty Opinions recommendation of Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing.

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Remuscularization of Ventricular Infarcts Using the Existing Cardiac Cells

Zhou, Y., & Zhang, J. J. (2022) · Springer eBooks · doi:10.1007/978-3-030-86140-7_4

microRNA Modulation

Castaño, I. M., Raftery, R. M., Curtin, C. M., Grillari, J., Redl, H. R., & O’Brien, F. J. (2019) · Springer eBooks · doi:10.1007/978-3-319-37076-7_34-1

Influencing factors and evaluation methods of cardiomyocyte proliferation

Fu, W., Wei, W. A. N. G., & Zeng, C. (2021) · Scientia Sinica Vitae · doi:10.1360/ssv-2020-0327

Neonatal Kalp Rejenerasyonu: Hippo Sinyal Yolağı’nın Rolü

ÖZKÜÇÜK, Y., & Tuli, A. (2022) · Arşiv Kaynak Tarama Dergisi · doi:10.17827/aktd.1030555

Myocardial Repair

Breckwoldt, K., & Eschenhagen, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99585-1

Stem Cells and Therapies in Cardiac Regeneration

Renikunta, H. V., Chakrabarti, R., Duddu, S., Bhattacharya, A., Chakravorty, N., & Shukla, P. C. (2023) · Springer eBooks · doi:10.1007/978-981-19-6008-6_7

Therapeutic Innovations for Heart Failure

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Dual Gene-Loaded Near-Infrared AIEgen Nanoplatforms with Promoted Proliferation, Relieved Immunosuppression, and Tracking Capabilities for Cardiomyocyte Transplantation

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Experimental validation and bioinformatics analysis of hub genes in myocardial infarction

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Innovative drug delivery technologies in myocardial infarction therapy

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Innovative nanotechnologies in the diagnosis and treatment of myocardial infarction: new horizons and perspectives

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Growth and proliferation of cardiomyocytes

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Dual Mechanism of Action: Exosomes from Human iPSC-Cardiomyocytes and Mesenchymal Stem Cells Restore Injured MyocardiumPreprint

Tzng, E., Bayardo, N., Ikeda, G., Takashima, H., Lyons, J. K., Bennett, M. V., O’Brien, C., & Yang, P. C.-M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.29.596548

Engineered Cardiac Tissues as a Platform for CRISPR‐Based Mitogen Discovery

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Peripheral Blood Mesenchymal Stem Cell–Derived Exosomes Improve Renal Sympathetic Denervation Efficacy Through β-Catenin-Mediated Cardiac ReprogrammingPreprint

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Cardiomyocyte Proliferation and Cardiac Cell Therapy

Li, F., & Zhu, W. (2025) · Springer eBooks · doi:10.1007/978-3-031-81743-4_9

The Role of the Autonomic Nervous System in Cardiovascular Toxicity

Carll, A. P., Reynolds, B. R., & Roberts, A. M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95488-4.00263-1

LncRNA Xist acts as a miR-486-5p sponge to modulate myoblast proliferation by recruiting Stk4

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MicroRNA-Mediated Regulatory Mechanisms in the Etiopathogenesis of Congenital Heart Disease

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miR-302 regulates pancreatic progenitor pool and pancreatic size

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RNA Mimics as Therapeutics for Cardiac Regeneration: A Paradigm Shift

Giacca, M. (2015) · Molecular Therapy · doi:10.1038/mt.2015.86

Additional file 6 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747036

Additional file 2 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747024

Additional file 2 of Time-regulated transcripts with the potential to modulate human pluripotent stem cell-derived cardiomyocyte differentiation

Muñoz, J. J. A. M., Dariolli, R., da Silva, C. M., Neri, E. A., Valadão, I. C., Turaça, L. T., Lima, V. M., de Carvalho, M. L. P., Velho, M., Sobie, E. A., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20887089

Additional file 12 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747051

Additional file 9 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747042

Additional file 3 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747027

Additional file 1 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747021

Additional file 10 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747045

Additional file 8 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747039

Additional file 11 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747048

Additional file 4 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747030

Additional file 5 of Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling

Bobis‐Wozowicz, S., Paw, M., Sarna, M., Kędracka–Krok, S., Nit, K., Błażowska, N., Dobosz, A., Hammad, R., Cathomen, T., Zuba‐Surma, E. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26747033

Cell and Gene Therapy in Heart Failure

Badimón, L., Mendieta, G., Vilahur, G., & Borrell-Pagés, M. (2025) · Springer eBooks · doi:10.1007/978-3-031-96562-3_15

The Application of Gene and Cell Therapies in Cardiac Repair

刘, 思. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.15123503

Novel Use of Autologous Cell Therapy in Ischemic Heart Failure

Fishkin, T., Khan, R., Materia, A. S., Patel, P., Rivero, H., Frishman, W. H., & Aronow, W. S. (2025) · Cardiology in Review · doi:10.1097/crd.0000000000001159

The harmonies played by miR-302/367 cluster in pluripotency, reprogramming, and rejuvenation

Zamanian, M., Moradi, S., & Baharvand, H. (2026) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szaf072

Molecular Regulation of Cardiomyocyte Cell Cycle and Regeneration

Li, F., Son, Y., Yang, M., & Zhu, W. (2026) · Biology · doi:10.3390/biology15070568

Rôle d'éphrine-B1 dans la morphologie et l'état post-mitotique du cardiomyocyte adulte : potentiel en régénération cardiaque

Cauquil, M. (2018) · theses.fr (ABES) · doi:10.70675/10c157c2z498fz4112z9078z46c41b806f10

Progeria de Hutchinson-Gilford : rôle des microARNs dans la régulation du cycle cellulaire et de l’induction de la sénescence

Delecourt, V. (2019) · theses.fr (ABES) · doi:10.70675/b5eb88aczb7f9z49dcza454z9bdb6a8216fc

From heart development to cardiac regeneration : identification of cardiomyocyte proliferation regulators

Payan, S. M. (2020) · theses.fr (ABES) · doi:10.70675/e54b0514zbb6bz4ed6zb634ze44b29ecc331

The role of MEIS inhibitors in cardiac regeneration and protection

Mammadova, A. (2024) · doi:10.70675/26f419bdzeecdz4816z8ff0z9800989c228b

Myocardial Repair

Breckwoldt, K., & Eschenhagen, T. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-15734-9.00159-x

Macrophage exosome-modified Mn/Se nanoheterostructure induces post-infarction cardiomyocyte regeneration and immunometabolic microenvironment repair

Guo, L., Xiong, Z., Sheng, K., Zhang, Q., Cheng, J., Xu, L., Wang, W., Zhang, G., Yao, T., Wang, D., et al. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04572-2

Cardiac regeneration and repair: the emerging mechanisms and therapeutic approaches

Li, Y., Zheng, K., Liu, Y., Li, R., Wang, S., Ye, W., Luo, Z., Li, X., Tao, Z., Xia, J., et al. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00504-6

Non-Coding RNAs from Cardiac Development to Disease: Regulatory Context, Regenerative Potential, and Translational Limits

Wang, L., Zhao, Y., Zhang, R., Ning, X., & Jin, B. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27177793

BindingDB Entry 50022615: Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration.

BindingDB (2025) · UC San Diego · doi:10.7270/q2m04b70

“Metabolic reprogramming as a central regulator of cardiomyocyte proliferation and heart regeneration”.

Kowalik, A., Paszenda, P., Frątczak, A., Suchecka, N., Popławska, P., Obrycka, P., Kita, J., & Woźniak, S. (2026) · Differentiation · doi:10.1016/j.diff.2026.101011

Abstract 259: A Microrna Pathway That Promotes Cardiomyocyte Proliferation And Cardiac Regeneration By Inhibiting Hippo Signaling

Tian, Y., Chen, L., Wang, T., Zhou, N., Kong, J., Liu, Y., Snitow, M. E., Morley, M. P., Li, D., Petrenko, N. B., et al. (2014) · Circulation Research · doi:10.1161/res.115.suppl_1.259

Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice

Nugroho, A. B., Stafford, N., Zi, M., Prehar, S., Potter, R., Kwon, D., Kohar, Y. S., Triastuti, E., Bùi, T. A., Cartwright, E. J., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.05.008 · Cited by 19

miRNA in cardiac development and regeneration

Ouyang, Z., & Wei, K. (2021) · Cell Regeneration · doi:10.1186/s13619-021-00077-5 · Cited by 77

RNA Mimics as Therapeutics for Cardiac Regeneration: A Paradigm Shift

Giacca, M. (2015) · Molecular Therapy · doi:10.1038/mt.2015.86

miR-301a-PTEN-AKT Signaling Induces Cardiomyocyte Proliferation and Promotes Cardiac Repair Post-MI

Zhen, L., Zhao, Q., Lü, J., Deng, S., Xu, Z., Zhang, L., Zhang, Y., Fan, H., Chen, X., Liu, Z., et al. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2020.08.033 · Cited by 35