Origin of the U87MG glioma cell line: Good news and bad news

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Barretina, J., Caponigro, G., Stransky, N., Venkatesan, K., Margolin, A. A., Kim, S., Wilson, C. J., Lehár, J., Kryukov, G. V., Sonkin, D., et al. (2012) · Nature · doi:10.1038/nature11003 · Cited by 7,950

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Lee, J., Kotliarova, S. E., Kotliarov, Y., Li, A., Su, Q., Donin, N. M., Pastorino, S., Purow, B. W., Christopher, N., Zhang, W., et al. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.03.030 · Cited by 2,345

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

Pollard, S. M., Yoshikawa, K., Clarke, I. D., Danovi, D., Stricker, S., Russell, R., Bayani, J., Head, R., Lee, M., Bernstein, M., et al. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.03.014 · Cited by 1,025

LONG TERM CULTURE OF NORMAL AND NEOPLASTIC HUMAN GLIA

Pontén, J., & Macintyre, E. H. (1968) · Acta Pathologica Microbiologica Scandinavica · doi:10.1111/j.1699-0463.1968.tb03502.x · Cited by 721

Absence of HeLa Cell Contamination in 169 Cell Lines Derived From Human Tumors2

Fogh, J., Wright, W. C., & Loveless, J. D. (1977) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/58.2.209 · Cited by 663

Check your cultures! A list of cross‐contaminated or misidentified cell lines

Capes‐Davis, A., Theodosopoulos, G., Atkin, I., Drexler, H. G., Kohara, A., MacLeod, R. A. F., Masters, J. R., Nakamura, Y., Reid, Y. A., Reddel, R. R., et al. (2010) · International Journal of Cancer · doi:10.1002/ijc.25242 · Cited by 520 · cited 1×

The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Y., Bergström, T., Jiang, Y., Johansson, P., Marinescu, V. D., Lindberg, N., Segerman, A., Wicher, G., Niklasson, M., Baskaran, S., et al. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.08.026 · Cited by 329

Cell line misidentification: the beginning of the end

American Type Culture Collection Standards Development Organization Workgroup ASN-0002 (2010) · Nature Reviews Cancer · doi:10.1038/nrc2852 · Cited by 266

DNA fingerprinting in forensics: past, present, future

Roewer, L. (2013) · Investigative Genetics · doi:10.1186/2041-2223-4-22 · Cited by 182

The Beginning of the End

Schraer, L., Borum, I., & Sathyan, T. G. (1995) · Cited by 113

Cytocidal effects of arenobufagin and hellebrigenin, two active bufadienolide compounds, against human glioblastoma cell line U-87

Han, L., Yuan, B., Shimada, R., Hayashi, H., Si, N., Zhao, H., Bian, B., & Takagi, N. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4567 · Cited by 36

Daam1 activates RhoA to regulate Wnt5a‑induced glioblastoma cell invasion

Liu, G., Yan, T., Li, X., Sun, J., Zhang, B., Wang, H., & Zhu, Y. (2017) · Oncology Reports · doi:10.3892/or.2017.6124 · Cited by 35

Association between SOX9 and CA9 in glioma, and its effects on chemosensitivity to TMZ

Xu, X., Wang, Z., Liu, N., Cheng, Y., Jin, W., Zhang, P., Wang, X., Yang, H., Liu, H., Zhang, Y., et al. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4382 · Cited by 35

miR-186 reverses cisplatin resistance and inhibits the�formation of the glioblastoma-initiating cell�phenotype by degrading Yin Yang 1 in glioblastoma

Li, J., Song, J., & Guo, F. (2018) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2018.3940 · Cited by 35

Intracellular stiffening competes with cortical softening in glioblastoma cells

Alibert, C., Pereira, D., Lardier, N., Etienne‐Manneville, S., Goud, B., Asnacios, A., & Manneville, J. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2021.120903 · Cited by 36

Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma

Шевченко, В. Е., Arnotskaya, N. E., Korneyko, M., Zaytsev, S., Khotimchenko, Y. S., Sharma, H., & Bryukhovetskiy, I. (2019) · Oncology Reports · doi:10.3892/or.2019.7043 · Cited by 34

GADD45A plays a protective role against temozolomide treatment in glioblastoma cells

Wang, H.-H., Chang, T., Lin, W.-C., Wei, K., & Shin, J.-W. (2017) · Scientific Reports · doi:10.1038/s41598-017-06851-3 · Cited by 33

Tissue-derived extracellular vesicles: Research progress from isolation to application

Qin, B., Hu, X., Su, Z., Zeng, X.-B., Ma, H., & Xiong, K. (2021) · Pathology - Research and Practice · doi:10.1016/j.prp.2021.153604 · Cited by 33

A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma

Way, G. P., Allaway, R. J., Bouley, S. J., Fadul, C. E., Sánchez, Y., & Greene, C. S. (2017) · BMC Genomics · doi:10.1186/s12864-017-3519-7 · Cited by 33

Venerable brain-cancer cell line faces identity crisis

Dolgin, E. (2016) · Nature · doi:10.1038/nature.2016.20515 · Cited by 33

Glioblastoma Vasculature: From its Critical Role in Tumor Survival to Relevant in Vitro Modelling

Pacheco, C., Martins, C., Monteiro, J., Baltazar, F., Costa, B. M., & Sarmento, B. F. C. C. (2022) · Frontiers in Drug Delivery · doi:10.3389/fddev.2022.823412 · Cited by 33

Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells

Ivanov, V. N., Wu, J., Wang, T. J. C., & Hei, T. K. (2019) · Oncotarget · doi:10.18632/oncotarget.26582 · Cited by 32

CKAP2 expression is associated with glioma tumor growth and acts as a prognostic factor in high‑grade�glioma

Wang, K., Huang, R., Li, G., Zeng, F., Zhao, Z., Liu, Y., Hu, H., & Jiang, T. (2018) · Oncology Reports · doi:10.3892/or.2018.6611 · Cited by 31

The function of histone methylation and acetylation regulators in GBM pathophysiology

McCornack, C. R., Woodiwiss, T. R., Hardi, A., Yano, H., & Kim, A. H. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1144184 · Cited by 33

Assessment of the proliferation status of glioblastoma cell and tumour tissue after nanoplatinum treatment

Kutwin, M., Sawosz, E., Jaworski, S., Wierzbicki, M., Strojny, B., Grodzik, M., & Chwalibóg, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178277 · Cited by 31

Convection-enhanced drug delivery for glioblastoma: A systematic review focused on methodological differences in the use of the convection-enhanced delivery method

Halle, B., Mongelard, K. B. G., & Poulsen, F. R. (2018) · Asian Journal of Neurosurgery · doi:10.4103/ajns.ajns_302_17 · Cited by 31

Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix

Umlauf, B. J., Clark, P. A., Lajoie, J. M., Georgieva, J. V., Bremner, S. B., Herrin, B. R., Kuo, J. S., & Shusta, E. V. (2019) · Science Advances · doi:10.1126/sciadv.aau4245 · Cited by 30

A 3D tumor spheroid model for the T98G Glioblastoma cell line phenotypic characterization

Oraiopoulou, M., Tampakaki, M., Tzamali, E., Tamiolakis, T., Makatounakis, V., Vakis, A. F., Zacharakis, G., Sakkalis, V., & Papamatheakis, J. D. (2019) · Tissue and Cell · doi:10.1016/j.tice.2019.05.007 · Cited by 30

Gradient hydrogels for screening stiffness effects on patient‐derived glioblastoma xenograft cellfates in 3D

Zhu, D., Trinh, P., Li, J., Grant, G., & Yang, F. (2020) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37093 · Cited by 30

Inkjet‐Patterned Microdroplets as Individual Microenvironments for Adherent Single Cell Culture

Xie, T., Zhang, Q., Zhang, W., Feng, S., & Lin, J. (2022) · Small · doi:10.1002/smll.202107992 · Cited by 29

The Mayo Clinic Florida Microdosimetric Kinetic Model of Clonogenic Survival: Application to Various Repair-Competent Rodent and Human Cell Lines

Parisi, A., Beltran, C. J., & Furutani, K. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012491 · Cited by 29

Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis

Magallón‐Lorenz, M., Terribas, E., Ortega‐Bertran, S., Creus‐Bachiller, E., Fernández, M. A., Requena, G., Rosas, I., Mazuelas, H., Uriarte-Arrazola, I., Negro, A., et al. (2023) · iScience · doi:10.1016/j.isci.2023.106096 · Cited by 31

Metabolic response of glioblastoma cells associated with glucose withdrawal and pyruvate substitution as revealed by GC-MS

Oppermann, H., Ding, Y., Sharma, J., Berndt‐Paetz, M., Meixensberger, J., Gaunitz, F., & Birkemeyer, C. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0131-9 · Cited by 29

Design, synthesis, DNA binding studies and evaluation of anticancer potential of novel substituted biscarbazole derivatives against human glioma U87 MG cell line

Kumar, N., Lal, N., Nemaysh, V., & Luthra, P. M. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.103911 · Cited by 29

Biomaterial-based in vitro 3D modeling of glioblastoma multiforme

Ahmed, T. (2023) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2023.01.002 · Cited by 31

Strategies for developing complex multi-component in vitro tumor models: Highlights in glioblastoma

DePalma, T. J., Sivakumar, H., & Skardal, A. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114067 · Cited by 30

Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

Fedorová, V., Pospíšilová, V., Váňová, T., Černá, K. A., Abaffy, P., Sedmík, J., Raška, J., Vochyánová, S., Matusova, Z., Houserova, J., et al. (2023) · Molecular Oncology · doi:10.1002/1878-0261.13389 · Cited by 30

Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells

Villodre, E. S., Kipper, F. C., Silva, A. O., Lenz, G., & Lopez, P. L. D. C. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0611-6 · Cited by 28

Sirtuin 1 knockdown inhibits glioma cell proliferation and potentiates temozolomide toxicity via facilitation of reactive oxygen species generation

Chen, H.-W., Lin, R. J., Zhang, Z., Wei, Q., Zhong, Z., Huang, J., & Xu, Y. (2019) · Oncology Letters · doi:10.3892/ol.2019.10235 · Cited by 27

Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids

Pettke, A., Tampere, M., Pronk, R., Wallner, O. A., Falk, A., Berglund, U. W., Helleday, T., Mirazimi, A., & Puumalainen, M.-R. (2020) · Viruses · doi:10.3390/v13010037 · Cited by 27

Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity

Schniewind, I., Hadiwikarta, W. W., Grajek, J., Poleszczuk, J., Richter, S., Peitzsch, M., Müller, J., Klusa, D., Beyreuther, E., Löck, S., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110422 · Cited by 27

Addressing blood-brain-tumor-barrier heterogeneity in pediatric brain tumors with innovative preclinical models

Morris, E. K., Daignault, S. M., Stehbens, S. J., Genovesi, L. A., & Lagendijk, A. K. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1101522 · Cited by 28

Copper induces neuron‐sparing, ferredoxin 1‐independent astrocyte toxicity mediated by oxidative stress

Gale, J. R., Hartnett, K. A., Ross, M. M., Rosenberg, P. A., & Aizenman, E. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15961 · Cited by 27

Knockdown of collagen α‑1(III) inhibits glioma cell proliferation and migration and is regulated by miR128‑3p

Gao, Y., Zhu, T., Chen, J., Liu, L., & Ouyang, R. (2018) · Oncology Letters · doi:10.3892/ol.2018.8830 · Cited by 27

Graphene oxide down-regulates genes of the oxidative phosphorylation complexes in a glioblastoma

Szmidt, M., Stankiewicz, A. M., Urbańska, K., Jaworski, S., Kutwin, M., Wierzbicki, M., Grodzik, M., Burzyńska, B., Góra, M., Chwalibóg, A., et al. (2019) · BMC Molecular Biology · doi:10.1186/s12867-018-0119-2 · Cited by 27

Emerging Roles of Primary Cilia in Glioma

Sarkisian, M. R., & Semple‐Rowland, S. L. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00055 · Cited by 27

Targeted suppression of glioma by ultralow-dose x-ray–induced photodynamic therapy and gold-based nanoclusters in preclinical models

Li, S., Chen, S., Li, Y., Sun, W., Li, J., Deng, H., Ding, H., Wang, Z., Zhu, L., Liu, J., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adq5331 · Cited by 27

Research advances and challenges in tissue-derived extracellular vesicles

Zhi, Z., Sun, Q., & Tang, W. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.1036746 · Cited by 26

μMESH-Enabled Sustained Delivery of Molecular and Nanoformulated Drugs for Glioblastoma Treatment

Mascolo, D. D., Guerriero, I., Pesce, C., Spanò, R., Palange, A. L., & Decuzzi, P. (2023) · ACS Nano · doi:10.1021/acsnano.3c01574 · Cited by 26

CRISPR/Cas9 Editing for Gaucher Disease Modelling

Pavan, E., Ormazábal, M., Peruzzo, P., Vaena, E., Rozenfeld, P. A., & Dardis, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093268 · Cited by 27

Transcriptomics predicts compound synergy in drug and natural product treated glioblastoma cells

Pruteanu, L.-L., Kopanitsa, L., Módos, D., Kletnieks, E., Samarova, E. I., Bender, A., Gomez, L. D., & Bailey, D. S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0239551 · Cited by 26

Mitochondrial dysfunction contributes to Rapamycin-induced apoptosis of Human Glioblastoma Cells - A synergistic effect with Temozolomide

Zimmerman, M. A., Wilkison, S. J., Qi, Q., Chen, G., & Li, P. A. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.40159 · Cited by 25

RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma

Zhou, J., Kong, Y. S., Vincent, K. M., Dieters‐Castator, D. Z., Bukhari, A. B., Glubrecht, D. D., Liu, R., Quilty, D., Findlay, S. D., Huang, X., et al. (2023) · Molecular Oncology · doi:10.1002/1878-0261.13434 · Cited by 25

One-Pot Aqueous Synthesis of Fluorescent Ag-In-Zn-S Quantum Dot/Polymer Bioconjugates for Multiplex Optical Bioimaging of Glioblastoma Cells

Mansur, A. A. P., Mansur, H. S., Carvalho, S. M., & Caires, A. J. (2017) · Contrast Media & Molecular Imaging · doi:10.1155/2017/3896107 · Cited by 25

Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma

Yang, Y., Lei, T., Du, S., Tong, R., Wang, H., Yang, J., Huang, J., Sun, M., Wang, Y., & Dong, Z. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4237 · Cited by 25

IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors

Joalland, N., Chauvin, C., Oliver, L., Vallette, F. M., Pecqueur, C., Jarry, U., & Scotet, E. (2018) · Journal of Immunotherapy · doi:10.1097/cji.0000000000000225 · Cited by 25

CADM2 inhibits human glioma proliferation, migration and invasion

Liu, N., Chen, Y., Bai, W., Wang, Z., Wang, X., Johnson, M., Wang, W., Zhang, P., Yang, H. W., Liu, H., et al. (2019) · Oncology Reports · doi:10.3892/or.2019.7010 · Cited by 25

3D Bioprinting Models for Glioblastoma: From Scaffold Design to Therapeutic Application

Branco, F., Cunha, J., Mendes, M., Sousa, J., & Vitorino, C. (2025) · Advanced Materials · doi:10.1002/adma.202501994 · Cited by 24

A systematic review and meta-analysis of topoisomerase inhibition in pre-clinical glioma models

Jue, T. R., Sena, E. S., Macleod, M. R., McDonald, K. L., & Hirst, T. C. (2018) · Oncotarget · doi:10.18632/oncotarget.24334 · Cited by 24

From glioma gloom to immune bloom: unveiling novel immunotherapeutic paradigms-a review

Regmi, M., Wang, Y., Liu, W., Dai, Y., Liu, S., Ma, K., Lin, G., Yang, J., Liu, H., Wu, J., et al. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-02973-5 · Cited by 24

Apatinib suppresses cell growth and metastasis and promotes antitumor activity of temozolomide in glioma

Wang, C., Jiang, M., Hou, H., Lin, Q., Yan, Z., & Zhang, X. (2018) · Oncology Letters · doi:10.3892/ol.2018.9355 · Cited by 24

Downregulation of SYT7 inhibits glioblastoma growth by promoting cellular apoptosis

Xiao, B., Li, J., Fan, Y., Ye, M., Lv, S., Xu, B., Chai, Y., Zhou, Z., Wu, M., & Zhu, X. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7723 · Cited by 23

Kinase-Modulated Bioluminescent Indicators Enable Noninvasive Imaging of Drug Activity in the Brain

Wu, Y., Walker, J. R., Westberg, M., Lin, N., Monje, M., Kirkland, T. A., Lin, M. Z., & Su, Y. (2023) · ACS Central Science · doi:10.1021/acscentsci.3c00074 · Cited by 23

Proteins of Wnt signaling pathway in cancer stem cells of human glioblastoma

Шевченко, В. Е., Arnotskaya, N. E., Zaitsev, S., Sharma, A., Sharma, H. S., Bryukhovetskiy, A. S., Pak, O., Khotimchenko, Y. S., & Bryukhovetskiy, I. (2020) · International review of neurobiology · doi:10.1016/bs.irn.2020.03.006 · Cited by 22

Multimodal study of CHI3L1 inhibition and its effect on angiogenesis, migration, immune response and refractive index of cellular structures in glioblastoma

Rusak, A., Buzalewicz, I., Mrozowska, M., Wiatrak, B., Haczkiewicz-Leśniak, K., Olbromski, M., Kmiecik, A. M., Krzyżak, E., Pietrowska, A., Moskal, J., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114520 · Cited by 22

MicroRNA‑370 suppresses the progression and proliferation of human astrocytoma and glioblastoma by negatively regulating β‑catenin and causing activation of FOXO3a

Lu, M., Wang, Y., Zhou, S., Xu, J., Li, J., Tao, R., & Zhu, Y. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5494 · Cited by 22

Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells

Liu, H.-J., Wang, L., Kang, L., Du, J., Li, S., & Cui, H. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000495274 · Cited by 22

Ecofriendly Multiphase Aqueous Colloidal Based on Carboxymethylcellulose Nanoconjugates with Luminescence Properties for Potential Bioimaging Cancer Cells

Paiva, A. E., & Borsagli, F. G. L. M. (2020) · Journal of Polymers and the Environment · doi:10.1007/s10924-020-01825-5 · Cited by 22

Human Brain Neuropharmacology: A Platform for Translational Neuroscience

Dragunow, M. (2020) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2020.09.002 · Cited by 23

Computer‑aided design of temozolomide derivatives based on alkylglycerone phosphate synthase structure with isothiocyanate and their pharmacokinetic/toxicity prediction and anti‑tumor activity in vitro

Yang, B., Li, X., He, L., & Zhu, Y. T. (2018) · Biomedical Reports · doi:10.3892/br.2018.1051 · Cited by 21

Molecular determinants of the interaction between glioblastoma CD133+ cancer stem cells and the extracellular matrix

Шевченко, В. Е., Arnotskaya, N. E., Pak, O., Sharma, A., Sharma, H. S., Khotimchenko, Y. S., Bryukhovetskiy, A. S., & Bryukhovetskiy, I. (2020) · International review of neurobiology · doi:10.1016/bs.irn.2020.03.005 · Cited by 21

Development and optimisation of in vitro sonodynamic therapy for glioblastoma

Keenlyside, A., Marples, T., Gao, Z., Hong, H., Nicely, L. G., Nogales, J., Li, H., Landgraf, L., Solth, A., Melzer, A., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-47562-2 · Cited by 21

Best practices for authenticating cell lines

Nims, R. W., & Reid, Y. (2017) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-017-0212-8 · Cited by 21

Modeling Microenvironmental Regulation of Glioblastoma Stem Cells: A Biomaterials Perspective

Heffernan, J. M., & Sirianni, R. W. (2018) · Frontiers in Materials · doi:10.3389/fmats.2018.00007 · Cited by 21

Integrated analysis identified core signal pathways and hypoxic characteristics of human glioblastoma

Gao, Y., Zhang, E., Liu, B., Zhou, K., He, S., Feng, L., Wu, G., Cao, M., Wu, H., Cui, Y., et al. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14507 · Cited by 21

Diosmin induces caspase-dependent apoptosis in human glioblastoma cells

SOARES, J. M., de Faria, B. M., Ascari, L. M., Alves‐Leon, S. V., de Souza, J. M., Soares, A. G., Cordeiro, Y., & Romão, L. F. (2019) · Anais da Academia Brasileira de Ciências · doi:10.1590/0001-3765201920191031 · Cited by 21

Zikavirus prME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy

Kretschmer, M., Kadlubowska, P., Hoffmann, D. E., Schwalbe, B., Auerswald, H., & Schreiber, M. (2020) · Cancers · doi:10.3390/cancers12041000 · Cited by 21

Radiotherapy of high-grade gliomas: dealing with a stalemate

Fròsina, G. (2023) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2023.104110 · Cited by 20

Neutrophils traffic in cancer nanodrugs

Osuka, S., & Meir, E. G. V. (2017) · Nature Nanotechnology · doi:10.1038/nnano.2017.82 · Cited by 20

Toxic effects of phytol and retinol on human glioblastoma cells are associated with modulation of cholesterol and fatty acid biosynthetic pathways

Facchini, G., Ignarro, R. S., Rodrigues-Silva, E., Vieira, A. S., Lopes‐Cendes, Í., Castilho, R. F., & Rogério, F. (2017) · Journal of Neuro-Oncology · doi:10.1007/s11060-017-2672-9 · Cited by 20

RIP2 promotes glioma cell growth by regulating TRAF3 and activating the NF‑κB and p38 signaling pathways

Cai, X., Yang, Y., Xia, W., Kong, H., Wang, M., Fu, W., Long, M., Hu, Y., & Xu, D. (2018) · Oncology Reports · doi:10.3892/or.2018.6397 · Cited by 20

C1q/ TNF ‐related peptide 8 ( CTRP 8) promotes temozolomide resistance in human glioblastoma

Thanasupawat, T., Głogowska, A., Burg, M., Krcek, J. P., Beiko, J., Pitz, M. W., Zhang, G., Hombach‐Klonisch, S., & Klonisch, T. C. (2018) · Molecular Oncology · doi:10.1002/1878-0261.12349 · Cited by 23

The efficacy and toxicity of ATM inhibition in glioblastoma initiating cells-driven tumor models

Fròsina, G., Marubbi, D., Marcello, D., Vecchio, D., & Daga, A. (2019) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2019.04.015 · Cited by 20

CXCR4-STAT3 Axis Plays a Role in Tumor Cell Infiltration in an Orthotopic Mouse Glioblastoma Model.

Han, J.-H., Yoon, J. S., Chang, D., Cho, K. G., Lim, J., Kim, S., & Suh‐Kim, H. (2020) · PubMed Central · doi:10.14348/molcells.2020.0098 · Cited by 20

Cytotoxic effect of boron application on glioblastoma cells

Aydın, H. E., Gündüz, M. K., Kızmazoğlu, C., Kandemir, T., & Arslantaş, A. (2020) · Turkish Neurosurgery · doi:10.5137/1019-5149.jtn.30316-20.1 · Cited by 20

Radiotherapy of High-Grade Gliomas: First Half of 2021 Update with Special Reference to Radiosensitization Studies

Fròsina, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168942 · Cited by 20

MAP30 promotes apoptosis of U251 and U87 cells by suppressing the LGR5 and Wnt/β-catenin signaling pathway, and enhancing Smac expression

Jiang, Y., Miao, J., Wang, D., Zhou, J., Liu, B., Jiao, F., Liang, J., Wang, Y., Fan, C., & Zhang, Q. (2018) · Oncology Letters · doi:10.3892/ol.2018.8073 · Cited by 20

Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy

Wilson, K. M., Mathews-Griner, L. A., Williamson, T., Guha, R., Chen, L., Shinn, P., McKnight, C. G., Michael, S., Klumpp-Thomas, C. A., Binder, Z. A., et al. (2018) · SLAS TECHNOLOGY · doi:10.1177/2472630318803749 · Cited by 20

The Tumorgenicity of Glioblastoma Cell Line U87MG Decreased During Serial In Vitro Passage

Zeng, Y., Wang, X., Wang, J., Yi, R., Long, H., Zhou, M., Luo, Q., Zhai, Z., Song, Y., & Qi, S. (2018) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-018-0592-7 · Cited by 19

Genetic manipulation of adhesion GPCR CD97/ADGRE5 modulates invasion in patient-derived glioma stem cells

Eichberg, D. G., Slepak, T. I., Pascoini, A. L., Komotar, R. J., & Ivan, M. E. (2021) · Journal of Neuro-Oncology · doi:10.1007/s11060-021-03778-8 · Cited by 19

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Pieri, V., Gallotti, A. L., Drago, D., Cominelli, M., Pagano, I., Conti, V., Valtorta, S., Coliva, A., Lago, S., Michelatti, D., et al. (2022) · Cancer Research · doi:10.1158/0008-5472.can-22-0677 · Cited by 19

Design and validation of a flowless gradient generating microfluidic device for high-throughput drug testing

Bachal, K., Yadav, S., Gandhi, P. S., & Majumder, A. (2022) · Lab on a Chip · doi:10.1039/d2lc00879c · Cited by 19

Boholamide A, an APD-Class, Hypoxia-Selective Cyclodepsipeptide

Torres, J. P., Lin, Z., Fenton, D. S., Leavitt, L. U., Niu, C., Lam, P., Robes, J. M. D., Peterson, R. T., Concepción, G. P., Haygood, M. G., et al. (2020) · Journal of Natural Products · doi:10.1021/acs.jnatprod.0c00038 · Cited by 18

Brain tumor vessels—a barrier for drug delivery

Hempel, C., Johnsen, K. B., Kostrikov, S., Hamerlik, P., & Andresen, T. L. (2020) · Cancer and Metastasis Reviews · doi:10.1007/s10555-020-09877-8 · Cited by 18

Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells

Paraiso, W. K. D., García-Chica, J., Ariza, X., Zagmutt, S., Fukushima, S., García, J., Mochida, Y., Serra, D., Herrero, L., Kinoh, H., et al. (2021) · Biomaterials Science · doi:10.1039/d1bm00689d · Cited by 18

Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

Schnöller, L. E., Piehlmaier, D., Weber, P., Brix, N., Fleischmann, D. F., Nieto, A. E., Selmansberger, M., Heider, T., Heß, J., Niyazi, M., et al. (2023) · Radiation Oncology · doi:10.1186/s13014-023-02241-4 · Cited by 19

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Mikhailova, V., Gulaia, V. S., Tiasto, V., Александрович, Р. С., Yatsunskaya, M., & Kagansky, A. (2018) · Global Medical Genetics · doi:10.3934/genet.2018.2.91 · Cited by 18

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Pin, G., Yu, Y., Tian, Z., Lin, Y., Qiu, Y., Yao, W., & Zhang, L. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4498 · Cited by 18

Single-cell tracking reveals super-spreading brain cancer cells with high persistence

Nousi, A., Søgaard, M. T., Audoin, M., & Jauffred, L. (2021) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2021.101120 · Cited by 19

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Oraiopoulou, M., Tzamali, E., Papamatheakis, J. D., & Sakkalis, V. (2021) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2021.3111744 · Cited by 17

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Song, T., Yao, M., Yang, Y., Liu, Z., Zhang, L., & Li, W. (2023) · Phenomics · doi:10.1007/s43657-023-00103-3 · Cited by 17

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Guo, S., Ramar, V., Guo, A. A., Saafir, T. B., Akpobiyeri, H., Hudson, B., Li, J., & Liu, M. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-04921-6 · Cited by 17

Function of neuronal nitric oxide synthase enzyme in temozolomide-induced damage of astrocytic tumor cells

Resende, F. F. B., Titze-de-Almeida, S. S., & Titze‐de‐Almeida, R. (2018) · Oncology Letters · doi:10.3892/ol.2018.7917 · Cited by 17

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Guo, G., Tian, A., Lan, X., Fu, C., Yan, Z., & Wang, C. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7418 · Cited by 17

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Umans, R. A., ten Kate, M., Pollock, C., & Sontheimer, H. W. (2020) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.0c00129 · Cited by 17

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Zhang, H., Huajun, S., Zhen, G., Yu, X., Liu, Q., Ziling, C., Zihao, S., Xia, Q., & Zhu, S. (2023) · BMC Cancer · doi:10.1186/s12885-023-11025-8 · Cited by 17

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Wang, Y., Song, W., Kan, P., Huang, C., Ma, Z., Wu, Q., Yao, X., & Zhang, B. (2018) · Oncology Reports · doi:10.3892/or.2018.6691 · Cited by 17

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Stabley, D. L., Holbrook, J., Harris, A. W., Swoboda, K. J., Crawford, T. O., Sol‐Church, K., & Butchbach, M. E. R. (2017) · Neuromuscular Disorders · doi:10.1016/j.nmd.2017.02.002 · Cited by 18

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Mu, F.-G., Liu, T., Zheng, H., Xie, X., Lei, T., He, X., Du, S., Tong, R., & Wang, Y. (2018) · Oncology Reports · doi:10.3892/or.2018.6756 · Cited by 16

การแสดงออกของยนและคณลกษณะของเซลลตนกำเนดมะเรงในประชากรเซลลไลน U87MG glioblastoma

บุตรศรี, ร. (2020) · doi:10.58837/chula.the.2020.685

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Nelander, S. (2017) · Molecular & Cellular Oncology · doi:10.1080/23723556.2017.1302907 · Cited by 1

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Jiang, Y., Marinescu, V. D., Xie, Y., Jarvius, M., Maturi, N. P., Haglund, C., Olofsson, S. K., Lindberg, N., Olofsson, T., Leijonmarck, C., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.04.053 · Cited by 14

Establishment of attached and non‐attached cell lines from an uncommon human glioma

Westermark, B., Larsson, E., Brunk, U. T., Lubitz, W., & Mark, J. (1981) · International Journal of Cancer · doi:10.1002/ijc.2910280314 · Cited by 17

A study of the origin of human glioma based on cell lines and tumor specimens

Timin, G., Лахина, Ю. С., Gulyaev, D. A., & Tolkunova, E. N. (2016) · Cell and Tissue Biology · doi:10.1134/s1990519x16020103