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Cited by 45

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Disturbed gut microbiota and bile homeostasis in Giardia -infected mice contributes to metabolic dysregulation and growth impairment

Riba, Ambre, Hassani, Kasra, Walker, Alesia, van Best, Niels, von Zeschwitz, Dunja, Anslinger, Teresa, Sillner, Nina, Rosenhain, Stefanie, Eibach, Daniel, Maiga-Ascofaré, Oumou, Rolle-Kampczyk, Ulrike, Basic, Marijana, Binz, Anne, Mocek, Sabine, Sodeik, Beate, Bauerfeind, Rudolf, Mohs, Antje, Trautwein, Christian, Kiessling, Fabian, May, Jürgen, Klingenspor, Martin, Gremse, Felix, Schmitt-Kopplin, Philippe, Bleich, André, Torow, Natalia, von Bergen, Martin, Hornef, Mathias W.·2020·Science Translational Medicine
DOI 10.1126/scitranslmed.aay7019
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Abstract

The protozoan parasite Giardia lamblia enhances bile secretion and microbiota–mediated bile acid deconjugation in mice, leading to growth impairment.

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Metadata

Authors
Riba, A., Hassani, K., Walker, A., van Best, N., von Zeschwitz, D., Anslinger, T., Sillner, N., Rosenhain, S., Eibach, D., Maiga-Ascofaré, O., Rolle-Kampczyk, U., Basic, M., Binz, A., Mocek, S., Sodeik, B., Bauerfeind, R., Mohs, A., Trautwein, C., Kiessling, F., May, J., Klingenspor, M., Gremse, F., Schmitt-Kopplin, P., Bleich, A., Torow, N., von Bergen, M., & Hornef, M. W.
Venue
Science Translational Medicine
Publisher
American Association for the Advancement of Science (AAAS)
Published
2020-10-14
Volume
12
Issue
565
ISSN
  • 1946-6234
  • 1946-6242
DOI
10.1126/scitranslmed.aay7019
Cited by
45
References
7
Language
en
Funders
  • Deutsche Forschungsgemeinschaft (SPP1656 HO2236/9-2, HO2236/14-1, HO2236/17-1, CRC1382 project A5, CRC1382 project A8, CRC1382 project B1, CRC1382 project Q1, SPP1656 BL953/5-2, BL953/5-2, CRC900 project C2 - Projektnummer 158989968 – SFB 900, CRC1371 project P13, TO1052/1-1)
  • Interdisciplinary Center for Clinical Research, Faculty of Medicine, RWTH Aachen University (Grant E8-13)
  • German Centrefor Infection Research (8000 201-3)
  • German Center for Infection Research (8000 201-3)
  • German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany (8000 201-3)

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