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Discovery of the First-in-Class Intestinal Restricted FXR and FABP1 Dual Modulator ZLY28 for the Treatment of Nonalcoholic Fatty Liver Disease

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Gypenosides Altered Hepatic Bile Acids Homeostasis in Mice Treated with High Fat Diet

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Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease

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Postbiotics Prepared Using Lactobacillus reuteri Ameliorates Ethanol‐Induced Liver Injury by Regulating the FXR/SHP/SREBP‐1c Axis

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Farnesoid X receptor: From Structure to Function and Its Pharmacology in Liver Fibrosis

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A novel role for farnesoid X receptor in the bile acid‐mediated intestinal glucose homeostasis

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The Nuclear Farnesoid X Receptor Reduces p53 Ubiquitination and Inhibits Cervical Cancer Cell Proliferation

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Molecular mechanism underlying the hypolipidemic effect of Shanmei Capsule based on network pharmacology and molecular docking

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A Possible Mechanism of Metformin in Improving Insulin Resistance in Diabetic Rat Models

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Farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5) signaling pathways improved the hepatic lipid metabolism in hybrid grouper

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Effects of maternal T-2 toxin exposure on the hepatic glycolipid metabolism in young mice

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Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma

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Fucoidan ameliorates alcohol-induced liver injury in mice through Parabacteroides distasonis-mediated regulation of the gut-liver axis

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Impact of gut microbiota and associated mechanisms on postprandial glucose levels in patients with diabetes

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Dietary β-Cryptoxanthin Inhibits High-Refined Carbohydrate Diet–Induced Fatty Liver via Differential Protective Mechanisms Depending on Carotenoid Cleavage Enzymes in Male Mice

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Gut Microbiota and Heart, Vascular Injury

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Ampelopsis grossedentata improves type 2 diabetes mellitus through modulating the gut microbiota and bile acid metabolism

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Signal Transduction and Molecular Regulation in Fatty Liver Disease

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Changes in circulating bile acid subtypes in response to weight-loss diets are associated with improvements in glycemic status and insulin resistance: The POUNDS Lost trial

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Potential use of seaweed polysaccharides as prebiotics for management of metabolic syndrome: a review

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Gut microbiota, bile acids, and nature compounds

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Pathological and therapeutic roles of bile acid metabolism and signaling in hepatocellular carcinoma: Insights from human and mouse studies

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Hepatic PHD2/HIF‐1α axis is involved in postexercise systemic energy homeostasis

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The bile acid induced hepatokine orosomucoid suppresses adipocyte differentiation

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Transcriptional Regulation of Hepatic Autophagy by Nuclear Receptors

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Dual derivatization strategy for the comprehensive quantification and double bond location characterization of fatty acids by ultra-high performance liquid chromatography-tandem mass spectrometry

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Geniposide dosage and administration time: Balancing therapeutic benefits and adverse reactions in liver disease treatment

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The Therapeutic Role of Xenobiotic Nuclear Receptors Against Metabolic Syndrome

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Improvement of obesity-induced fatty liver disease by intermittent hypoxia exposure in a murine model

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Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease

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Probiotics protect against hepatic steatosis in tris (2-chloroethyl) phosphate-induced metabolic disorder of mice via FXR signaling

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Obeticholic acid alleviates intrauterine growth restriction induced by di-ethyl-hexyl phthalate in pregnant female mice by improving bile acid disorder

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The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids

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Body Composition and Senescence: Impact of Polyphenols on Aging-Associated Events

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The long and the small collide: LncRNAs and small heterodimer partner (SHP) in liver disease

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Alterations in intestinal bile acid transport provide a therapeutic target in patients with post-bariatric hypoglycaemia

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Obeticholic acid aggravates liver fibrosis by activating hepatic farnesoid X receptor-induced apoptosis in cholestatic mice

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Beyond Farnesoid X receptor to target new therapies for NAFLD

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Liver-specific Nr1h4 deletion in mice with human-like bile acid composition causes severe liver injury

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The important role of fatty infiltration of skeletal muscle in aging: skeletal muscle function, pathological mechanisms, and intervention

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Bile acid signaling, metabolism, and aging

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Association between lipid accumulation products and relative handgrip strength: a large population-based study

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The contribution of small heterodimer partner to the occurrence and progression of cholestatic liver injury

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Roles and potential mechanisms of hepatic stellate cells activation mediated by epigenetics through insulin like growth factor 1 and receptor: A review

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The Molecular Mechanism of Farnesoid X Receptor Alleviating Glucose Intolerance in Turbot (Scophthalmus maximus)

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Squid cartilage type II collagen accelerates osteoporotic fractures healing through regulating homocysteine mediated EGF and FBN1 signals

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Bile acid regulation of xenobiotic nuclear receptors on the expressions of orosomucoids in the liver

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Dietary bile acid supplementation improves the intestinal health and growth performance of piglets partially through the FXR/AQPs pathway

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Drug-gut Microbiome Interaction in Atherosclerosis Therapeutics

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Farnesoid X receptor is inhibited after ileum transposition in diabetic rats: its hypoglycemic effect

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Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

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Prevention of Cholestatic Liver Disease Through BCL6-FXR Enterohepatic Crosstalk

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Microcystin-LR Disrupts Bile Acid Homeostasis, Driving Cholestatic Liver Injury and Gallstones via FXR/SHP Antagonism

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Therapeutic Approaches for Nonalcoholic Steatohepatitis ( NASH )

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Correlation between Skeletal Muscle Mass Index and Visceral Fat Area in Type 2 Diabetes Patients with Sarcopenia

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Research Progress of Animal Models of Type II Diabetes

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Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice

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Ageing Fxr Deficient Mice Develop Increased Energy Expenditure, Improved Glucose Control and Liver Damage Resembling NASH

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Beyond Farnesoid X receptor to target new therapies for NAFLD

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