The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.
A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease
Open accessAbstract
The second X chromosome confers resilience in a mouse model of Alzheimer’s disease potentially through the X-linked gene Kdm6a .
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“Sex is an important factor that contributes to the clinical and biological heterogeneities in Alzheimer’s disease (AD)”
From Sex-specific DNA methylation differences in Alzheimer’s disease pathology (2021) · cites this paper as [9]
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“it has also been reported men with AD have an increased risk for death [9–11]”
From Sex-specific DNA methylation differences in Alzheimer’s disease pathology (2021) · cites this paper as [9]
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Bates, D., Mächler, M., Bolker, B., & Walker, S. (2015) · Journal of Statistical Software · doi:10.18637/jss.v067.i01 · Cited by 86,835
Hirono, N., Mori, E., Ikejiri, Y., Imamura, T., Shimomura, T., Hashimoto, M., Yamashita, H., & Ikeda, M. (1997) · PubMed · Cited by 21,012
Kok, J. S., Berg, I. J., & Scherder, E. J. A. (2013) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000353441 · Cited by 20,589
Conducting Meta-Analyses in R with the metafor Package
Viechtbauer, W. (2010) · Journal of Statistical Software · doi:10.18637/jss.v036.i03 · Cited by 20,464
Older Adults' Reasons for Using Technology while Aging in Place
Peek, S. T. M., Luijkx, K. G., Rijnaard, M. D., Nieboer, M. E., van der Voort, C. S., Aarts, S., van Hoof, J., Vrijhoef, H. J., & Wouters, E. (2015) · Gerontology · doi:10.1159/000430949 · Cited by 19,852
Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly
Kangas, M., Korpelainen, R., Vikman, I., Nyberg, L., & Jämsä, T. J. (2014) · Gerontology · doi:10.1159/000362720 · Cited by 19,007
Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359
A scaling normalization method for differential expression analysis of RNA-seq data
Robinson, M. D., & Oshlack, A. (2010) · Genome Biology · doi:10.1186/gb-2010-11-3-r25 · Cited by 7,876
dbSNP: the NCBI database of genetic variation
Sherry, S. T. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.1.308 · Cited by 7,502
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Sex differences in biological aging with a focus on human studies
Hägg, S., & Jylhävä, J. (2021) · eLife · doi:10.7554/elife.63425 · Cited by 442
“DOI: https://doi.org/10.7554/eLife.63425 16 of 27 AD symptoms (Davis, 2020).”
InfluentialMechanisms of sex differences in Alzheimer’s disease
Lopez-Lee, C., Torres, E. R. S., Carling, G., & Gan, L. (2024) · Neuron · doi:10.1016/j.neuron.2024.01.024 · Cited by 376
Sex and gender differences in cognitive resilience to aging and Alzheimer's disease
Arenaza‐Urquijo, E. M., Boyle, R., Casaletto, K., Anstey, K. J., Vila‐Castelar, C., Colverson, A., Palpatzis, E., Eissman, J. M., Kheng Siang Ng, T., Raghavan, S., et al. (2024) · Alzheimer's & Dementia · doi:10.1002/alz.13844 · Cited by 223
Self-citationSex Differences in Alzheimer’s Disease: Insights From the Multiomics Landscape
Guo, L., Zhong, M. B., Zhang, L., Zhang, B., & Cai, D. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.02.968 · Cited by 164
Small molecule cognitive enhancer reverses age-related memory decline in mice
Krukowski, K., Nolan, A., Frias, E. S., Boone, M., Ureta, G., Grue, K. A., Paladini, M. S., Elizarraras, E., Delgado, L. M., Bernales, S., et al. (2020) · eLife · doi:10.7554/elife.62048 · Cited by 167
Metadata
- Authors
- Davis, E. J., Broestl, L., Abdulai-Saiku, S., Worden, K., Bonham, L. W., Miñones-Moyano, E., Moreno, A. J., Wang, D., Chang, K., Williams, G., Garay, B. I., Lobach, I., Devidze, N., Kim, D., Anderson-Bergman, C., Yu, G.-Q., White, C. C., Harris, J. A., Miller, B. L., Bennett, D. A., Arnold, A. P., De Jager, P. L., Palop, J. J., Panning, B., Yokoyama, J. S., Mucke, L., & Dubal, D. B.
- Affiliations
- University of California, San Francisco (US)
- Gladstone Institutes (US)
- Broad Institute (US)
- Allen Institute for Brain Science (US)
- Rush University Medical Center (US)
- University of California, Los Angeles (US)
- Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA.
- Corresponding author
- Davis, Emily J.
- Broestl, Lauren
- Dubal, Dena B.
- ORCID
- Davis, Emily J.
- Broestl, Lauren
- Abdulai-Saiku, Samira
- Worden, Kurtresha
- Bonham, Luke W.
- Miñones-Moyano, Elena
- Moreno, Arturo J.
- Wang, Dan
- Chang, Kevin
- Williams, Gina
- Garay, Bayardo I.
- Lobach, Iryna
- Kim, Daniel
- Anderson-Bergman, Cliff
- White, Charles C.
- Harris, Julie A.
- Miller, Bruce L.
- Bennett, David A.
- Arnold, Arthur P.
- De Jager, Phil L.
- Palop, Jorge J.
- Panning, Barbara
- Yokoyama, Jennifer S.
- Mucke, Lennart
- Dubal, Dena B.
- Venue
- Science Translational Medicine
- Published
- 2020-08-26
- Volume
- 12
- Issue
- 558
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC8409261
- OpenAlex
- W3080470877
- Cited by
- 176
- References
- 141
- Citations by year
- 2026: 19 · 2025: 32 · 2024: 28 · 2023: 26 · 2022: 44 · 2021: 21 · 2020: 6
- FWCI
- 14.59
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Science Foundation (1650113)
- National Institutes of Health (AG023501, NS043196, AG011385 and NS065780, P30AG10161, R01AG15819, and R01AG17917, U01AG46152 and U01AG61356, CTSI UL1 TR000004, AG049152, NS092918 and AG034531, R01AG36836)
- Larry L. Hillblom Foundation
- American Federation for Aging Research
- Glenn Foundation for Medical Research
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- Alzheimer's disease, X chromosome, sex chromosomes, resilience, cognitive decline, aging, preclinical Alzheimer's disease, mouse model, brain gene expression, disease susceptibility
- MeSH terms
- Alzheimer Disease, Animals, Female, Male, Sex Characteristics, Testis, X Chromosome, Y Chromosome, Mice
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