Cited by 99Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensingBacterial Identification and Susceptibility Testing

Enhancement of in vitro growth of pathogenic bacteria by norepinephrine: importance of inoculum density and role of transferrin

Open access
O'Donnell, Phyllis M., Aviles, Hernan, Lyte, Mark, Sonnenfeld, Gerald·2006·Applied and Environmental Microbiology

Abstract

Norepinephrine is a stress hormone that enhances bacterial growth. We examined the effects of a small inoculum on the norepinephrine-induced growth of species previously reported to be unaffected by norepinephrine. The results indicated that a reduced inoculum density is essential for observing norepinephrine-induced effects. Additional studies using serum-free media suggested that transferrin plays a role in norepinephrine-induced growth.

Integrity signals

Registry

Crossref · 10.1128/aem.00075-06

Cites

38 of 38 references verified0 citation errors · 0 not checkable

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Bacterial growth promotion by host stress molecules is not unique to P aeruginosa and is also seen with Streptococcus pneumoniae, S aureus, and Klebsiella pneumoniae.

    “Bacterial growth promotion by host stress molecules is not unique to P aeruginosa, and is also seen with Streptococcus pneumoniae,121 S aureus,122 and Klebsiella pneumoniae.”

    From The microbiome and critical illness (2016) · cites this paper as [122]

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Authors
O'Donnell, P. M., Aviles, H., Lyte, M., & Sonnenfeld, G.
Affiliations
  • Binghamton University (US)
  • Department of Biological Sciences, Binghamton University, State University of New York, Binghamton, New York 13902
  • Texas Tech University (US)
Venue
Applied and Environmental Microbiology
Published
2006-07
Volume
72
Issue
7
Pages
5097-5099
ISSN
  • 0099-2240 (ISSN-L)
  • 1098-5336
OpenAlex
W2086963814
Cited by
99
References
38
Citations by year
2026: 5 · 2025: 4 · 2024: 4 · 2023: 9 · 2022: 7 · 2021: 6 · 2020: 9 · 2019: 8 · 2018: 5 · 2017: 3 · 2016: 6 · 2015: 4 · 2014: 2 · 2013: 7 · 2012: 2
FWCI
1.70
Type
journal article
Language
en
Open access
Locations
  • Applied and Environmental Microbiology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Aeronautics and Space Administration (NCC958)
  • National Space Biomedical Research Institute (NCC 9‐58)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
Keywords
norepinephrine, bacterial growth enhancement, pathogenic bacteria, inoculum size, transferrin, serum-free medium, stress hormones, iron acquisition
MeSH terms
Culture Media, Gram-Negative Bacteria, Humans, Norepinephrine, Staphylococcus aureus, Transferrin, Colony Count, Microbial

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