Cited by 396Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensingReceptor Mechanisms and Signaling

Catecholamine induced growth of gram negative bacteria

Lyte, Mark, Ernst, Sharon·1992·Life Sciences

Abstract

The addition of various catecholamines to cultures of gram negative bacteria resulted in dramatic increases in growth. The ability of norepinephrine, epinephrine, dopamine and dopa to enhance the growth of Escherichia coli, Yersinia enterocolitica and Pseudomonas aeruginosa was observed to be dependent on the bacterium employed with each strain showing marked preference for one or more of the catecholamines. Catecholamine induced increases in growth were confirmed by one or more of the following methods: uptake of tritiated thymidine into newly synthesized DNA, changes in optical density or pour plate analysis. None of the catecholamine metabolites resulting from either oxidative deamination or catechol-O-methylation were able to effect similar increases in bacterial growth as compared to either norepinephrine, epinephrine or dopamine. Norepinephrine was consistently observed to effect the greatest increase in bacterial growth for all strains tested.

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Crossref · 10.1016/0024-3205(92)90273-r

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9 of 9 references verified0 citation errors · 0 not checkable

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  • Bacteria produce noradrenaline as a quorum sensing molecule, and noradrenaline and adrenaline can promote pathogenesis and growth.

    “bacteria produce noradrenaline as a quorum sensing molecule, and noradrenaline and adrenaline can promote pathogenesis and growth (229, 230)”

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Authors
Lyte, M., & Ernst, S.
Affiliations
Minnesota State University, Mankato (US)
Corresponding author
Lyte, Mark
Venue
Life Sciences
Publisher
Elsevier BV
Published
1992-01
Volume
50
Issue
3
Pages
203-212
ISSN
0024-3205 (ISSN-L)
OpenAlex
W2085147597
Cited by
396
References
9
Citations by year
2026: 11 · 2025: 18 · 2024: 19 · 2023: 20 · 2022: 20 · 2021: 31 · 2020: 24 · 2019: 23 · 2018: 23 · 2017: 11 · 2016: 25 · 2015: 11 · 2014: 20 · 2013: 13 · 2012: 13
FWCI
0.66
Type
journal article
Language
en
Open access
closed
Locations
  • Life Sciences (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r29mh045246-05)
  • Directorate for Biological Sciences
  • National Institute of Mental Health (MH45246)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
Keywords
catecholamines, bacterial growth stimulation, Gram-negative bacteria, norepinephrine, epinephrine, dopamine, DOPA, Escherichia coli, Yersinia enterocolitica, Pseudomonas aeruginosa, catecholamine metabolites, oxidative deamination, DNA synthesis
MeSH terms
Catecholamines, Escherichia coli, Gram-Negative Bacteria, Microbiological Techniques, Phenotype, Pseudomonas aeruginosa, Yersinia enterocolitica, Colony Count, Microbial

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