Redirecting Reductant Flux into Hydrogen Production via Metabolic Engineering of Fermentative Carbon Metabolism in a Cyanobacterium

Hydrogen production by biological processes: a survey of literature

Das, D. (2001) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(00)00058-6 · Cited by 2,097 · see citing works

Water Suppression That Works. Excitation Sculpting Using Arbitrary Wave-Forms and Pulsed-Field Gradients

Hwang, T., & Shaka, A. J. (1995) · Journal of Magnetic Resonance Series A · doi:10.1006/jmra.1995.1047 · Cited by 1,934 · see citing works

Aquatic phototrophs: efficient alternatives to land-based crops for biofuels

Dismukes, G. C., Carrieri, D., Bennette, N., Ananyev, G. M., & Posewitz, M. C. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.05.007 · Cited by 733 · see citing works

[7] Chemical procedures for analysis of polysaccharides

Hassid, W. Z., & Abraham, S. (1957) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(57)03345-5 · Cited by 712 · see citing works

The fermentation pathways of Escherichia coli

Clark, D. P. (1989) · FEMS Microbiology Reviews · doi:10.1016/0168-6445(89)90033-8 · Cited by 506 · see citing works

Enhancement of hydrogen production by Enterobacter cloacae IIT-BT 08

Kumar, N., & Das, D. (2000) · Process Biochemistry · doi:10.1016/s0032-9592(99)00109-0 · Cited by 412 · see citing works

Rapid simultaneous lipid extraction and transesterification for fatty acid analyses

Rodríguez‐Ruiz, J., Belarbi, E., Sánchez, J. L. G., & Alonso, D. L. (1998) · Biotechnology Techniques · doi:10.1023/a:1008812904017 · Cited by 354 · see citing works

Plant genetic engineering to improve biomass characteristics for biofuels

Sticklen, M. B. (2006) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2006.05.003 · Cited by 313 · see citing works

Fermentation in cyanobacteria

Stal, L. (1997) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(97)00056-9 · Cited by 301 · see citing works

Enzymatic production of biohydrogen

Woodward, J., Orr, M. T., Cordray, K., & Greenbaum, E. (2000) · Nature · doi:10.1038/35016633 · Cited by 269 · see citing works

THE PRODUCTION OF HYDROGEN PEROXIDE BY BLUE‐GREEN ALGAE: A SURVEY 1

Stevens, S. E., Patterson, C. O. P., & Myers, J. E. (1973) · Journal of Phycology · doi:10.1111/j.1529-8817.1973.tb04116.x · Cited by 244 · see citing works

Mutation of the ptsG Gene Results in Increased Production of Succinate in Fermentation of Glucose by Escherichia coli

Chatterjee, R., Millard, C. S., Champion, K. M., Clark, D. P., & Donnelly, M. I. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.1.148-154.2001 · Cited by 217 · see citing works

Enhanced hydrogen production from glucose by metabolically engineered Escherichia coli

Maeda, T., Sánchez-Torres, V., & Wood, T. K. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-007-1217-0 · Cited by 196 · see citing works

Hydrogen production of Enterobacter aerogenes altered by extracellular and intracellular redox states

Nakashimada, Y., Rachman, M. A., Kakizono, T., & Nishio, N. (2002) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(02)00128-3 · Cited by 189 · see citing works

Enhanced hydrogen production in altered mixed acid fermentation of glucose by Enterobacter aerogenes

Rachman, M. A., Furutani, Y., Nakashimada, Y., Kakizono, T., & Nishio, N. (1997) · Journal of Fermentation and Bioengineering · doi:10.1016/s0922-338x(97)80142-0 · Cited by 172 · see citing works

Enhanced hydrogen production from glucose using ldh- and frd-inactivated Escherichiacoli strains

Yoshida, A., Nishimura, T., Kawaguchi, H., Inui, M., & Yukawa, H. (2006) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0456-9 · Cited by 164 · see citing works

New gentamicin-resistance and lacZ promoter-probe cassettes suitable for insertion mutagenesis and generation of transcriptional fusions

Becker, A., Schmidt, M., Jäger, W., & Pühler, A. (1995) · Gene · doi:10.1016/0378-1119(95)00313-u · Cited by 145 · see citing works

Optimization of Metabolic Capacity and Flux through Environmental Cues To Maximize Hydrogen Production by the Cyanobacterium “ <i>Arthrospira</i> ( <i>Spirulina</i> ) <i>maxima</i> ”

Ananyev, G., Carrieri, D., & Dismukes, G. C. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.01078-08 · Cited by 125 · see citing works

Inhibition of respiration and nitrate assimilation enhances photohydrogen evolution under low oxygen concentrations in Synechocystis sp. PCC 6803

Gutthann, F., Egert, M., Marques, A., & Appel, J. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2006.12.003 · Cited by 124 · see citing works

The fermentation pathways of Escherichia coli

Clark, D. P. (1989) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1989.tb03398.x · Cited by 123 · see citing works

Feasibility studies on the fermentative hydrogen production by recombinant Escherichia coli BL-21

Chittibabu, G., Nath, K., & Das, D. (2005) · Process Biochemistry · doi:10.1016/j.procbio.2005.08.020 · Cited by 122 · see citing works

Formation of l-alanine as a reduced end product in carbohydrate fermentation by the hyperthermophilic archaeon Pyrococcus furiosus

Kengen, S. W. M., & Stams, A. J. M. (1994) · Archives of Microbiology · doi:10.1007/bf00276479 · Cited by 121 · see citing works

Modulation of Acetone-Butanol-Ethanol Fermentation by Carbon Monoxide and Organic Acids

Datta, R., & Zeikus, J. G. (1985) · Applied and Environmental Microbiology · doi:10.1128/aem.49.3.522-529.1985 · Cited by 119 · see citing works

Growth at low temperature causes nitrogen limitation in the cyanobacterium Synechococcus sp. PCC 7002

Sakamoto, T., & Bryant, D. A. (1997) · Archives of Microbiology · doi:10.1007/s002030050535 · Cited by 100 · see citing works

Multiple mechanisms controlling carbon metabolism in bacteria

Saier, M. H. (1998) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19980420)58:2/3 · Cited by 97 · see citing works

Redirection of biochemical pathways for the enhancement of H2 production by Enterobacter cloacae

Kumar, N., Ghosh, A., & Das, D. (2001) · Biotechnology Letters · doi:10.1023/a:1010334803961 · Cited by 95 · see citing works

Reductive pentose phosphate-independent CO2 fixation in Rhodobacter sphaeroides and evidence that ribulose bisphosphate carboxylase/oxygenase activity serves to maintain the redox balance of the cell

Wang, X., Falcone, D. L., & Tabita, F. R. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.11.3372-3379.1993 · Cited by 80 · see citing works

Occurrence of poly-beta-hydroxybutyrate in Spirulina species

VINCENZINI, M. T., Sili, C., Philippis, R. D., Ena, A., & Materassi, R. (1990) · Journal of Bacteriology · doi:10.1128/jb.172.5.2791-2792.1990 · Cited by 78 · see citing works

Redistribution of Metabolic Fluxes inEscherichia coliwith Fermentative Lactate Dehydrogenase Overexpression and Deletion

Yang, Y., San, K., & Bennett, G. N. (1999) · Metabolic Engineering · doi:10.1006/mben.1998.0111 · Cited by 73 · see citing works

Renewable hydrogen production by cyanobacteria: Nickel requirements for optimal hydrogenase activity

Carrieri, D., Ananyev, G., Costas, A. M. G., Bryant, D. A., & Dismukes, G. C. (2008) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2008.02.022 · Cited by 63 · see citing works

Characterization of two cytochrome oxidase operons in the marine cyanobacterium Synechococcus sp. PCC 7002: Inactivation of ctaDI affects the PS I:PS II ratio

Nomura, C. T., Persson, S., Shen, G., Inoue‐Sakamoto, K., & Bryant, D. A. (2006) · Photosynthesis Research · doi:10.1007/s11120-005-8533-y · Cited by 48 · see citing works

Identification of hox genes and analysis of their transcription in the unicellular cyanobacterium Gloeocapsa alpicola CALU 743 growing under nitrate-limiting conditions

Sheremetieva, M. E., Troshina, O. Y., Serebryakova, L. T., & Lindblad, P. C. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb11352.x · Cited by 29 · see citing works

Identification and quantification of water‐soluble metabolites by cryoprobe‐assisted nuclear magnetic resonance spectroscopy applied to microbial fermentation

Carrieri, D., McNeely, K., Roo, A. C. D., Bennette, N. B., Pelczer, I., & Dismukes, G. C. (2009) · Magnetic Resonance in Chemistry · doi:10.1002/mrc.2420 · Cited by 28 · see citing works

Alanine as an end product during fermentation of monosaccharides byClostridium strain P2

�rlygsson, J., Anderson, R. G. G., & Svensson, B. (1995) · Antonie van Leeuwenhoek · doi:10.1007/bf00874136 · Cited by 22 · see citing works

Construction and Characterization of Fermentative Lactate Dehydrogenase Escherichia coli Mutant and Its Potential for Bacterial Hydrogen Production

Sode, K., Watanabe, M., Makimoto, H., & Tomiyama, M. (1999) · Humana Press eBooks · doi:10.1007/978-1-4612-1604-9_29 · Cited by 20 · see citing works

Construction and Characterization of Fermentative Lactate Dehydrogenase Escherichia coli Mutant and Its Potential for Bacterial Hydrogen Production

Sode, K., Mika, W., Makimoto, H., & Tomiyama, M. (1999) · Applied Biochemistry and Biotechnology · doi:10.1385/abab:77:1-3:317 · Cited by 14 · see citing works

Interfacing nature’s catalytic machinery with synthetic materials for semi-artificial photosynthesis

Kornienko, N., Zhang, J., Sakimoto, K. K., Yang, P., & Reisner, E. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0251-7 · Cited by 531 · see citing works

Engineering cyanobacteria to generate high-value products

Ducat, D. C., Way, J. C., & Silver, P. A. (2011) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.12.003 · Cited by 507 · see citing works

Photosynthetic semiconductor biohybrids for solar-driven biocatalysis

Cestellos-Blanco, S., Zhang, H., Kim, J. M., Shen, Y., & Yang, P. (2020) · Nature Catalysis · doi:10.1038/s41929-020-0428-y · Cited by 462 · see citing works

Synechococcus elongatus UTEX 2973, a fast growing cyanobacterial chassis for biosynthesis using light and CO2

Yu, J., Liberton, M., Cliften, P. F., Head, R. D., Jacobs, J., Smith, R. D., Koppenaal, D., Brand, J. J., & Pakrasi, H. B. (2015) · Scientific Reports · doi:10.1038/srep08132 · Cited by 372 · see citing works

Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering

Quintana, N., Van der Kooy, F., Van de Rhee, M. D., Voshol, G. P., & Verpoorte, R. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3394-0 · Cited by 338 · see citing works

CRISPR/Cas9 mediated targeted mutagenesis of the fast growing cyanobacterium Synechococcus elongatus UTEX 2973

Wendt, K. E., Ungerer, J., Cobb, R. E., Zhao, H., & Pakrasi, H. B. (2016) · Microbial Cell Factories · doi:10.1186/s12934-016-0514-7 · Cited by 232 · see citing works

Cyanobacteria: Promising biocatalysts for sustainable chemical production

Knoot, C. J., Ungerer, J., Wangikar, P. P., & Pakrasi, H. B. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.r117.815886 · Cited by 225 · see citing works

Application of synthetic biology in cyanobacteria and algae

Wang, B., Wang, J., Zhang, W., & Meldrum, D. R. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00344 · Cited by 211 · see citing works

Cyanobacteria: Photoautotrophic Microbial Factories for the Sustainable Synthesis of Industrial Products

Lau, N., Matsui, M., & Abdullah, A. A. (2015) · BioMed Research International · doi:10.1155/2015/754934 · Cited by 196 · see citing works

Metabolic engineering of microorganisms for biofuel production

Majidian, P., Tabatabaei, M., Zeinolabedini, M., Naghshbandi, M. P., & Yusuf Chisti, B. (2017) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2017.10.085 · Cited by 191 · see citing works

Cofactor engineering for more efficient production of chemicals and biofuels

Wang, M., Chen, B., Fang, Y., & Tan, T. (2017) · Biotechnology Advances · doi:10.1016/j.biotechadv.2017.09.008 · Cited by 171 · see citing works

Development of Synechocystis sp. PCC 6803 as a Phototrophic Cell Factory

Yu, Y., You, L., Liu, D., Hollinshead, W. D., Tang, Y., & Zhang, F. (2013) · Marine Drugs · doi:10.3390/md11082894 · Cited by 154 · see citing works

Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications

Grama, S. B., Liu, Z., & Li, J. (2022) · Marine Drugs · doi:10.3390/md20050285 · Cited by 157 · see citing works

Measuring Methane Production from Ruminants

Hill, J., McSweeney, C. S., Wright, A. G., Bishop-Hurley, G. J., & Kalantar‐Zadeh, K. (2015) · Trends in biotechnology · doi:10.1016/j.tibtech.2015.10.004 · Cited by 150 · see citing works

Designing and creating a modularized synthetic pathway in cyanobacterium Synechocystis enables production of acetone from carbon dioxide

Zhou, J., Zhang, H., Zhang, Y., Li, Y., & Ma, Y. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.03.005 · Cited by 142 · see citing works

Biosynthesis of platform chemical 3-hydroxypropionic acid (3-HP) directly from CO2 in cyanobacterium Synechocystis sp. PCC 6803

Wang, Y., Sun, T., Gao, X., Shi, M., Wu, L., Chen, L., & Zhang, W. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.10.008 · Cited by 139 · see citing works

Transcription Profiling of the Model Cyanobacterium Synechococcus sp. Strain PCC 7002 by Next-Gen (SOLiD™) Sequencing of cDNA

Ludwig, M., & Bryant, D. A. (2011) · Frontiers in Microbiology · doi:10.3389/fmicb.2011.00041 · Cited by 136 · see citing works

Altered carbohydrate metabolism in glycogen synthase mutants of Synechococcus sp. strain PCC 7002: Cell factories for soluble sugars

Xu, Y., Guerra, T., Li, Z., Ludwig, M., Dismukes, G. C., & Bryant, D. A. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.12.002 · Cited by 131 · see citing works

Rewiring hydrogenase-dependent redox circuits in cyanobacteria

Ducat, D. C., Sachdeva, G., & Silver, P. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016026108 · Cited by 130 · see citing works

Photoautotrophic production of D-lactic acid in an engineered cyanobacterium

Varman, A. M., Yu, Y., You, L., & Tang, Y. (2013) · Microbial Cell Factories · doi:10.1186/1475-2859-12-117 · Cited by 130 · see citing works

Engineering cyanobacteria as photosynthetic feedstock factories

Hays, S. G., & Ducat, D. C. (2014) · Photosynthesis Research · doi:10.1007/s11120-014-9980-0 · Cited by 122 · see citing works

Genome Features and Biochemical Characteristics of a Robust, Fast Growing and Naturally Transformable Cyanobacterium Synechococcus elongatus PCC 11801 Isolated from India

Jaiswal, D., Sengupta, A., Sohoni, S. V., Sengupta, S., Phadnavis, A. G., Pakrasi, H. B., & Wangikar, P. P. (2018) · Scientific Reports · doi:10.1038/s41598-018-34872-z · Cited by 120 · see citing works

Technologies for Biofuel Production: Current Development, Challenges, and Future Prospects

Kour, D., Rana, K. L., Yadav, N., Yadav, A. N., Rastegari, A. A., Singh, C., Negi, P., Singh, K., & Saxena, A. K. (2019) · Biofuel and Biorefinery Technologies · doi:10.1007/978-3-030-14463-0_1 · Cited by 121 · see citing works

Cyanobacteria as a Promising Alternative for Sustainable Environment: Synthesis of Biofuel and Biodegradable Plastics

Agarwal, P., Soni, R., Kaur, P., Madan, A., Mishra, R., Pandey, J., Singh, S., & Singh, G. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.939347 · Cited by 118 · see citing works

The role of the bidirectional hydrogenase in cyanobacteria

Carrieri, D., Wawrousek, K., Eckert, C. A., Yu, J., & Maness, P. (2011) · Bioresource Technology · doi:10.1016/j.biortech.2011.03.103 · Cited by 112 · see citing works

Engineered cyanobacteria: Teaching an old bug new tricks

Ruffing, A. M. (2011) · Bioengineered Bugs · doi:10.4161/bbug.2.3.15285 · Cited by 107 · see citing works

Biofilm architecture: An emerging synthetic biology target

Kassinger, S. J., & van Hoek, M. L. (2020) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2020.01.001 · Cited by 102 · see citing works

Microalgal Hydrogen Production

Wang, Y., Yang, H., Zhang, X., Han, F., Tu, W., & Yang, W. (2020) · Small Methods · doi:10.1002/smtd.201900514 · Cited by 101 · see citing works

Improving photosynthesis and metabolic networks for the competitive production of phototroph-derived biofuels

Work, V. H., D’Adamo, S., Radakovits, R., Jinkerson, R. E., & Posewitz, M. C. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.11.022 · Cited by 96 · see citing works

Microbial paths to renewable hydrogen production

Hallenbeck, P. C. (2011) · Biofuels · doi:10.4155/bfs.11.6 · Cited by 97 · see citing works

Glycogen production for biofuels by the euryhaline cyanobacteria Synechococcus sp. strain PCC 7002 from an oceanic environment

Aikawa, S., Nishida, A., Ho, S., Chang, J., Hasunuma, T., & Kondo, A. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-88 · Cited by 97 · see citing works

Metabolic engineering of cyanobacteria for the photosynthetic production of succinate

Lan, E. I., & Wei, C. T. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2016.10.014 · Cited by 94 · see citing works

An overview on progress, advances, and future outlook for biohydrogen production technology

Brar, K. K., Cortez, A. A., Pellegrini, V. O. A., Amulya, K., Polikarpov, I., Magdouli, S., Kumar, M., Yang, Y., Bhatia, S. K., & Brar, S. K. (2022) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2022.01.156 · Cited by 93 · see citing works

Boosting Autofermentation Rates and Product Yields with Sodium Stress Cycling: Application to Production of Renewable Fuels by Cyanobacteria

Carrieri, D., Momot, D., Brasg, I. A., Ananyev, G., Lenz, O., Bryant, D. A., & Dismukes, G. C. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00975-10 · Cited by 91 · see citing works

Photobiological hydrogen production: Bioenergetics and challenges for its practical application

Sakurai, H., Masukawa, H., Kitashima, M., & Inoue, K. (2013) · Journal of Photochemistry and Photobiology C Photochemistry Reviews · doi:10.1016/j.jphotochemrev.2013.05.001 · Cited by 91 · see citing works

Cyanobacteria as Chassis for Industrial Biotechnology: Progress and Prospects

Al‐Haj, L., Lui, Y. T., Abed, R. M. M., Gomaa, M., & Purton, S. (2016) · Life · doi:10.3390/life6040042 · Cited by 90 · see citing works

The fourth generation of biofuel

Moravvej, Z., Makarem, M. A., & Rahimpour, M. R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815162-4.00020-3 · Cited by 87 · see citing works

Cyanobacterial Hydrogenases and Hydrogen Metabolism Revisited: Recent Progress and Future Prospects

Khanna, N., & Lindblad, P. C. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160510537 · Cited by 86 · see citing works

Proteomic analysis reveals resistance mechanism against biofuel hexane in Synechocystis sp. PCC 6803

Liu, J., Chen, L., Wang, J., Qiao, J., & Zhang, W. (2012) · Biotechnology for Biofuels · doi:10.1186/1754-6834-5-68 · Cited by 83 · see citing works

An LC–MS-Based Chemical and Analytical Method for Targeted Metabolite Quantification in the Model Cyanobacterium Synechococcus sp. PCC 7002

Bennette, N. B., Eng, J. F., & Dismukes, G. C. (2011) · Analytical Chemistry · doi:10.1021/ac200108a · Cited by 83 · see citing works

Biological hydrogen with industrial potential: Improvement and prospection in biohydrogen production

Chen, W., Li, T., Ren, Y., Wang, J., Chen, H., & Wang, Q. (2022) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2022.135777 · Cited by 83 · see citing works

Genetic manipulation of a metabolic enzyme and a transcriptional regulator increasing succinate excretion from unicellular cyanobacterium

Osanai, T., Shirai, T., Iijima, H., Nakaya, Y., Okamoto, M., Kondo, A., & Hirai, M. Y. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01064 · Cited by 81 · see citing works

Temperature enhanced succinate production concurrent with increased central metabolism turnover in the cyanobacterium Synechocystis sp. PCC 6803

Hasunuma, T., Matsuda, M., Kato, Y., Vavricka, C. J., & Kondo, A. (2018) · Metabolic Engineering · doi:10.1016/j.ymben.2018.05.013 · Cited by 77 · see citing works

Recent Applications of Metabolomics Toward Cyanobacteria

Schwarz, D., Orf, I., Kopka, J., & Hagemann, M. (2013) · Metabolites · doi:10.3390/metabo3010072 · Cited by 80 · see citing works

Cyanobacterial nitrogenases: phylogenetic diversity, regulation and functional predictions

Esteves-Ferreira, A. A., Cavalcanti, J. H. F., Vaz, M. G. M. V., de Alvarenga, L. V., Nunes‐Nesi, A., & Araújo, W. L. (2017) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2016-0050 · Cited by 80 · see citing works

An extended siderophore suite from Synechococcus sp. PCC 7002 revealed by LC-ICPMS-ESIMS

Boiteau, R. M., & Repeta, D. J. (2015) · Metallomics · doi:10.1039/c5mt00005j · Cited by 76 · see citing works

Improved sugar-free succinate production by Synechocystis sp. PCC 6803 following identification of the limiting steps in glycogen catabolism

Hasunuma, T., Matsuda, M., & Kondo, A. (2016) · Metabolic Engineering Communications · doi:10.1016/j.meteno.2016.04.003 · Cited by 72 · see citing works

Rerouting of carbon flux in a glycogen mutant of cyanobacteria assessed via isotopically non‐stationary 13C metabolic flux analysis

Hendry, J. I., Prasannan, C. B., Ma, F., Möllers, K. B., Jaiswal, D., Digmurti, M. G., Allen, D. K., Frigaard, N., Dasgupta, S., & Wangikar, P. P. (2017) · Biotechnology and Bioengineering · doi:10.1002/bit.26350 · Cited by 74 · see citing works

A Hybrid Flux Balance Analysis and Machine Learning Pipeline Elucidates Metabolic Adaptation in Cyanobacteria

Vijayakumar, S., Rahman, P. K. S. M., & Angione, C. (2020) · iScience · doi:10.1016/j.isci.2020.101818 · Cited by 69 · see citing works

Potential of Hydrogen Production From Biomass

Singh, V., & Das, D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814251-6.00003-4 · Cited by 67 · see citing works

Computational evaluation of Synechococcus sp. PCC 7002 metabolism for chemical production

Vu, T. T., Hill, E. A., Kucek, L. A., Konopka, A. E., Beliaev, A. S., & Reed, J. L. (2013) · Biotechnology Journal · doi:10.1002/biot.201200315 · Cited by 67 · see citing works

Metabolomics-assisted synthetic biology

Ellis, D. I., & Goodacre, R. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.10.014 · Cited by 66 · see citing works

Functional Genomics of Novel Secondary Metabolites from Diverse Cyanobacteria Using Untargeted Metabolomics

Baran, R., Ivanova, N., Jose, N., García‐Pichel, F., Kyrpides, N. C., Gugger, M. F., & Northen, T. R. (2013) · Marine Drugs · doi:10.3390/md11103617 · Cited by 61 · see citing works

Cyanobacteria: A metabolic power house for harvesting solar energy to produce bio-electricity and biofuels

Sarma, M. K., Kaushik, S., & Goswami, P. (2016) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2016.03.043 · Cited by 60 · see citing works

Hydrogen Production by Cyanobacteria

Hallenbeck, P. C. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1208-3_2 · Cited by 58 · see citing works

Metabolic and genetic engineering of cyanobacteria for enhanced hydrogen production

Khetkorn, W., Khanna, N., Incharoensakdi, A., & Lindblad, P. C. (2013) · Biofuels · doi:10.4155/bfs.13.41 · Cited by 57 · see citing works

Reprogramming the glycolytic pathway for increased hydrogen production in cyanobacteria: metabolic engineering of NAD+-dependent GAPDH

Kumaraswamy, G. K., Guerra, T., Qian, X., Zhang, S., Bryant, D. A., & Dismukes, G. C. (2013) · Energy & Environmental Science · doi:10.1039/c3ee42206b · Cited by 56 · see citing works

Recent advances and challenges of the use of cyanobacteria towards the production of biofuels

Singh, V., Chaudhary, D. K., Mani, I., & Dhar, P. K. (2016) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2016.01.099 · Cited by 55 · see citing works

Renewable Hydrogen from Biomass: Technological Pathways and Economic Perspectives

Rey, J. R. C., Mateos-Pedrero, C., Longo, A., Rijo, B., Brito, P., Ferreira, P., & Nobre, C. (2024) · Energies · doi:10.3390/en17143530 · Cited by 53 · see citing works

An overview on biofuel and biochemical production by photosynthetic microorganisms with understanding of the metabolism and by metabolic engineering together with efficient cultivation and downstream processing

Sarkar, D., & Shimizu, K. (2015) · Bioresources and Bioprocessing · doi:10.1186/s40643-015-0045-9 · Cited by 55 · see citing works

Cyanoremediation: A Green-Clean Tool for Decontamination of Synthetic Pesticides from Agro- and Aquatic Ecosystems

Kumar, A., & Singh, J. S. (2017) · Springer eBooks · doi:10.1007/978-3-319-49727-3_4 · Cited by 53 · see citing works

Metabolic Pathways for Photobiological Hydrogen Production by Nitrogenase- and Hydrogenase-containing Unicellular Cyanobacteria Cyanothece

Skizim, N. J., Ananyev, G., Krishnan, A., & Dismukes, G. C. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.302125 · Cited by 50 · see citing works

Nanomaterials for enhancing photosynthesis: interaction with plant photosystems and scope of nanobionics in agriculture

Mony, C., Kaur, P., Rookes, J. E., Callahan, D. L., Eswaran, S. V., Yang, W. R., & Manna, P. K. (2022) · Environmental Science Nano · doi:10.1039/d2en00451h · Cited by 48 · see citing works

Natural osmolytes are much less effective substrates than glycogen for catabolic energy production in the marine cyanobacterium Synechococcus sp. strain PCC 7002

Guerra, T., Xu, Y., Bennette, N. B., McNeely, K., Bryant, D. A., & Dismukes, G. C. (2013) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2013.04.005 · Cited by 47 · see citing works

Flux balance analysis of photoautotrophic metabolism: Uncovering new biological details of subsystems involved in cyanobacterial photosynthesis

Qian, X., Kim, M. K., Kumaraswamy, G. K., Agarwal, A., Lun, D. S., & Dismukes, G. C. (2016) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2016.12.007 · Cited by 46 · see citing works

Genetic engineering contribution to developing cyanobacteria-based hydrogen energy to reduce carbon emissions and establish a hydrogen economy

Kamshybayeva, G. K., Kossalbayev, B. D., Sadvakasova, A. K., Kakimova, A. B., Bauenova, M. O., Zayadan, B. K., Lan, C.-W., Alwasel, S. H., Tomo, T., Chang, J., et al. (2023) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2022.12.342 · Cited by 44 · see citing works

Malic Enzyme Facilitates d -Lactate Production through Increased Pyruvate Supply during Anoxic Dark Fermentation in Synechocystis sp. PCC 6803

Hidese, R., Matsuda, M., Osanai, T., Hasunuma, T., & Kondo, A. (2020) · ACS Synthetic Biology · doi:10.1021/acssynbio.9b00281 · Cited by 43 · see citing works

Anionic metabolite biosynthesis enhanced by potassium under dark, anaerobic conditions in cyanobacteria

Ueda, S., Kawamura, Y., Iijima, H., Nakajima, M., Shirai, T., Okamoto, M., Kondo, A., Hirai, M. Y., & Osanai, T. (2016) · Scientific Reports · doi:10.1038/srep32354 · Cited by 42 · see citing works

Cofactor engineering in cyanobacteria to overcome imbalance between NADPH and NADH: A mini review

Park, J., & Choi, Y. (2017) · Frontiers of Chemical Science and Engineering · doi:10.1007/s11705-016-1591-1 · Cited by 41 · see citing works

Growth of Chlamydomonas reinhardtii in acetate-free medium when co-cultured with alginate-encapsulated, acetate-producing strains of Synechococcus sp. PCC 7002

Therien, J., Zadvornyy, O. A., Posewitz, M. C., Bryant, D. A., & Peters, J. W. (2014) · Biotechnology for Biofuels · doi:10.1186/s13068-014-0154-2 · Cited by 41 · see citing works

Synechococcus sp. Strain PCC 7002 nifJ Mutant Lacking Pyruvate:Ferredoxin Oxidoreductase

McNeely, K., Xu, Y., Ananyev, G., Bennette, N. B., Bryant, D. A., & Dismukes, G. C. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.02792-10 · Cited by 38 · see citing works

Isolation of wild microalgae from natural water bodies for high hydrogen producing strains

He, M., Li, L., & Liu, J. (2011) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2011.11.089 · Cited by 36 · see citing works

Production of Bioplastic Compounds by Genetically Manipulated and Metabolic Engineered Cyanobacteria

Katayama, N., Iijima, H., & Osanai, T. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0854-3_7 · Cited by 36 · see citing works

State-of-the-Art Genetic Modalities to Engineer Cyanobacteria for Sustainable Biosynthesis of Biofuel and Fine-Chemicals to Meet Bio–Economy Challenges

Khan, A. Z., Bilal, M., Mehmood, S., Sharma, A. K., & Iqbal, H. M. N. (2019) · Life · doi:10.3390/life9030054 · Cited by 36 · see citing works

Nanotechnology in Plant Nanobionics: Mechanisms, Applications, and Future Perspectives

Gautam, K., Singh, H., & Sinha, A. K. (2025) · Advanced Biology · doi:10.1002/adbi.202400589 · Cited by 35 · see citing works

Enhancement of bio-hydrogen generation by spirulina via an electrochemical photo-bioreactor (EPBR)

Hasnaoui, S., Pauss, A., Abdi, N., Grib, H., & Mameri, N. (2020) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2019.12.144 · Cited by 35 · see citing works

CRISPRi-enhanced direct photosynthetic conversion of carbon dioxide to succinic acid by metabolically engineered cyanobacteria

Lai, M. J., Tsai, J. C., & Lan, E. I. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.128131 · Cited by 35 · see citing works

Ability of marine cyanobacterium Synechococcus sp. VDW to remove ammonium from brackish aquaculture wastewater

Srimongkol, P., Thongchul, N., Phunpruch, S., & Karnchanatat, A. (2018) · Agricultural Water Management · doi:10.1016/j.agwat.2018.09.006 · Cited by 33 · see citing works

Enhancing biological hydrogen production from cyanobacteria by removal of excreted products

Ananyev, G., Skizim, N. J., & Dismukes, G. C. (2012) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2012.03.026 · Cited by 33 · see citing works

Four-carbon dicarboxylic acid production through the reductive branch of the open cyanobacterial tricarboxylic acid cycle in Synechocystis sp. PCC 6803

Iijima, H., Watanabe, A., Sukigara, H., Iwazumi, K., Shirai, T., Kondo, A., & Osanai, T. (2021) · Metabolic Engineering · doi:10.1016/j.ymben.2021.03.007 · Cited by 32 · see citing works

Dark fermentative hydrogen production by the unicellular halotolerant cyanobacterium Aphanothece halophytica grown in seawater

Taikhao, S., Incharoensakdi, A., & Phunpruch, S. (2014) · Journal of Applied Phycology · doi:10.1007/s10811-014-0292-8 · Cited by 31 · see citing works

Sorbitol production and optimization of photosynthetic supply in the cyanobacterium Synechocystis PCC 6803

Chin, T., Okuda, Y., & Ikeuchi, M. (2018) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2018.04.004 · Cited by 30 · see citing works

Construction of a chassis for hydrogen production: physiological and molecular characterization of a Synechocystis sp. PCC 6803 mutant lacking a functional bidirectional hydrogenase

Pinto, F., van Elburg, K. A., Pacheco, C. C., Lopo, M., Noirel, J., Montagud, A., Urchueguía, J. F., Wright, P. C., & Tamagnini, P. (2011) · Microbiology · doi:10.1099/mic.0.052282-0 · Cited by 30 · see citing works

Lauric Acid Production in a Glycogen-Less Strain of Synechococcus sp. PCC 7002

Work, V. H., Melnicki, M. R., Hill, E. A., Davies, F. K., Kucek, L. A., Beliaev, A. S., & Posewitz, M. C. (2015) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2015.00048 · Cited by 29 · see citing works

Introduction to algal fuels

Yusuf Chisti, B. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64192-2.00001-9 · Cited by 27 · see citing works

Effects of selected electron transport chain inhibitors on 24-h hydrogen production by Synechocystis sp. PCC 6803

Burrows, E. H., Chaplen, F. W. R., & Ely, R. L. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.10.042 · Cited by 27 · see citing works

Maximizing reductant flow into microbial H2 production

Kontur, W. S., Noguera, D. R., & Donohue, T. J. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.10.003 · Cited by 26 · see citing works

Influence of culture age, ammonium and organic carbon in hydrogen production and nutrient removal by Anabaena sp. in nitrogen-limited cultures

Vargas, S. R., Zaiat, M., & Calijuri, M. D. C. (2020) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2020.08.072 · Cited by 25 · see citing works

Sigma Factor Modulation for Cyanobacterial Metabolic Engineering

Srivastava, A., Varshney, R. K., & Shukla, P. (2020) · Trends in Microbiology · doi:10.1016/j.tim.2020.10.012 · Cited by 25 · see citing works

Combinatorial use of environmental stresses and genetic engineering to increase ethanol titres in cyanobacteria

Andrews, F., Faulkner, M., Toogood, H. S., & Scrutton, N. S. (2021) · Biotechnology for Biofuels · doi:10.1186/s13068-021-02091-w · Cited by 23 · see citing works

Metabolic transformation of cyanobacteria for biofuel production

Velmurugan, R., & Incharoensakdi, A. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.134342 · Cited by 23 · see citing works

Designing intracellular metabolism for production of target compounds by introducing a heterologous metabolic reaction based on a Synechosystis sp. 6803 genome-scale model

Shirai, T., Osanai, T., & Kondo, A. (2016) · Microbial Cell Factories · doi:10.1186/s12934-016-0416-8 · Cited by 22 · see citing works

Advances in Utilizing Cyanobacteria for Hydrogen Production

Kufryk, G. I. (2013) · Advances in Microbiology · doi:10.4236/aim.2013.36a008 · Cited by 22 · see citing works

Chirality Matters: Synthesis and Consumption of the d -Enantiomer of Lactic Acid by Synechocystis sp. Strain PCC6803

Angermayr, S. A., van der Woude, A. D., Correddu, D., Kern, R., Hagemann, M., & Hellingwerf, K. J. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.03379-15 · Cited by 22 · see citing works

Distribution of Hydrogenases in Cyanobacteria: A Phylum-Wide Genomic Survey

Puggioni, V., Tempel, S., & Latifi, A. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00223 · Cited by 22 · see citing works

Determination of Volatile Organic Compounds and Antibacterial Activity of the Amazonian Cyanobacterium Synechococcus sp. Strain GFB01

do Amaral, S. C., Santos, A. V., Schneider, M. P. C., da Silva, J. K. R., & Xavier, L. P. (2020) · Molecules · doi:10.3390/molecules25204744 · Cited by 21 · see citing works

Rewiring of Cyanobacterial Metabolism for Hydrogen Production: Synthetic Biology Approaches and Challenges

Krishnan, A., Qian, X., Ananyev, G., Lun, D. S., & Dismukes, G. C. (2018) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-0854-3_8 · Cited by 20 · see citing works

Production of Clean Energy from Cyanobacterial Biochemical Products

Hossain, M. F. (2016) · Strategic Planning for Energy and the Environment · doi:10.1080/10485236.2017.11810168 · Cited by 20 · see citing works

Modulation of Medium-Chain Fatty Acid Synthesis in Synechococcus sp. PCC 7002 by Replacing FabH with a Chaetoceros Ketoacyl-ACP Synthase

Gu, H., Jinkerson, R. E., Davies, F. K., Sisson, L. A., Schneider, P. E., & Posewitz, M. C. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00690 · Cited by 19 · see citing works

Phytoplankton community structure and diversity in the indoor industrial aquaculture system for Litopenaeus vannamei revealed by high‐throughput sequencing and morphological identification

Qiao, L., Chang, Z., Li, J., Chen, Z., Yang, L., & Luo, Q. (2019) · Aquaculture Research · doi:10.1111/are.14213 · Cited by 18 · see citing works

Boosting cyanobacterial H 2 production through metabolic engineering

(2016) · Biotechnology and Bioengineering · doi:10.1002/bit.25767

Metabolic switching of central carbon metabolism in response to nitrate: Application to autofermentative hydrogen production in cyanobacteria

McNeely, K., Kumaraswamy, G. K., Guerra, T., Bennette, N. B., Ananyev, G., & Dismukes, G. C. (2014) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.04.004 · Cited by 16 · see citing works

Consequences of ccmR deletion on respiration, fermentation and H 2 metabolism in cyanobacterium Synechococcus sp . PCC 7002

Krishnan, A., Zhang, S., Liu, Y., Tadmori, K. A., Bryant, D. A., & Dismukes, G. C. (2015) · Biotechnology and Bioengineering · doi:10.1002/bit.25913 · Cited by 6 · see citing works

Metabolic Engineering of Light and Dark Biochemical Pathways in Wild-Type and Mutant Strains of Synechocystis PCC 6803 for Maximal, 24-Hour Production of Hydrogen Gas

Ely, R. L., USDOE, & Chaplen, F. W. R. (2014) · doi:10.2172/1122862

Effects of increasing the NAD(H) pool on hydrogen production and metabolic flux distribution in Enterobacter aerogenes mutants

Wang, J., Yu, W., Xu, L., Wang, S., & Yan, Y. (2013) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2013.07.121 · Cited by 36 · see citing works