Rewiring of Cyanobacterial Metabolism for Hydrogen Production: Synthetic Biology Approaches and Challenges
Abstract
With the demand for renewable energy growing, hydrogen (H 2 ) is becoming an attractive energy carrier. Developing H 2 production technologies with near-net zero carbon emissions is a major challenge for the "H 2 economy." Certain cyanobacteria inherently possess enzymes, nitrogenases, and bidirectional hydrogenases that are capable of H 2 evolution using sunlight, making them ideal cell factories for photocatalytic conversion of water to H 2 . With the advances in synthetic biology, cyanobacteria are currently being developed as a "plug and play" chassis to produce H 2 . This chapter describes the metabolic pathways involved and the theoretical limits to cyanobacterial H 2 production and summarizes the metabolic engineering technologies pursued.
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Arthrospira maxima is one of the most efficient hydrogen-producing cyanobacterium.
“Arthrospira maxima is one of the most efficient hydrogen-producing cyanobacterium 4,5”
From The Draft Genome of a Hydrogen-producing Cyanobacterium, <i>Arthrospira platensis</i> NIES-46 (2019) · cites this paper as [5]
Cites
Energy conservation in chemotrophic anaerobic bacteria
Thauer, R. K., Jungermann, K., & Decker, K. (1977) · Bacteriological Reviews · doi:10.1128/br.41.1.100-180.1977 · Cited by 4,146 · see citing works
Hydrogen production by biological processes: a survey of literature
Das, D. (2001) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(00)00058-6 · Cited by 2,097 · see citing works
The ecology of cyanobacteria: their diversity in time and space.
Whitton, B. A., & Potts, M. (2000) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-46855-7 · Cited by 1,429 · see citing works
The Molecular Biology of Cyanobacteria
(1994) · Springer eBooks · doi:10.1007/978-94-011-0227-8 · Cited by 1,429 · see citing works
Analysis of optimality in natural and perturbed metabolic networks
Segrè, D., Vitkup, D., & Church, G. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.232349399 · Cited by 1,375 · see citing works
Structure/Function Relationships of [NiFe]- and [FeFe]-Hydrogenases
Fontecilla-Camps, J. C., Volbeda, A., Cavazza, C., & Nicolet, Y. (2007) · Chemical Reviews · doi:10.1021/cr050195z · Cited by 1,339 · see citing works
Classification and phylogeny of hydrogenases
Vignais, P. M., Billoud, B., & Meyer, J. (2001) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2001.tb00587.x · Cited by 1,185 · see citing works
Biological hydrogen production; fundamentals and limiting processes
Hallenbeck, P. C. (2002) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(02)00131-3 · Cited by 1,123 · see citing works
Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde
Atsumi, S., Higashide, W., & Liao, J. C. (2009) · Nature Biotechnology · doi:10.1038/nbt.1586 · Cited by 870 · see citing works
Reconstruction of biochemical networks in microorganisms
Feist, A. M., Herrgård, M. J., Thiele, I., Reed, J. L., & Palsson, B. Ø. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1949 · Cited by 859 · see citing works
The structure and mechanism of iron-hydrogenases
Adams, M. W. W. (1990) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(90)90044-5 · Cited by 757 · see citing works
Nitrogen Control in Cyanobacteria
Herrero, A., Muro-Pastor, A. M., & Flores, E. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.2.411-425.2001 · Cited by 735 · see citing works
Rena, A. B. (1997) · Crop Protection · doi:10.1016/s0261-2194(97)81187-8 · Cited by 706 · see citing works
Lindberg, P., Park, S., & Melis, A. (2010) · Metabolic Engineering · doi:10.1016/j.ymben.2009.10.001 · Cited by 596 · see citing works
Park, J. H., Lee, K. H., Kim, T. Y., & Lee, S. Y. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702609104 · Cited by 592 · see citing works
Hydrogenases and Hydrogen Metabolism of Cyanobacteria
Tamagnini, P., Axelsson, R., Lindberg, P., Oxelfelt, F., Wünschiers, R., & Lindblad, P. C. (2002) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.66.1.1-20.2002 · Cited by 530 · see citing works
Nitrogen fixation and photosynthetic oxygen evolution in cyanobacteria
Berman-Frank, I., Lundgren, P., & Falkowski, P. (2003) · Research in Microbiology · doi:10.1016/s0923-2508(03)00029-9 · Cited by 522 · see citing works
Cyanobacterial HeterocystsPreprint
Kumar, K. P., Mella-Herrera, R. A., & Golden, J. W. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000315 · Cited by 511 · see citing works
Molecular biology of cyanobacterial salt acclimation
Hagemann, M. (2010) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2010.00234.x · Cited by 510 · see citing works
[FeFe]- and [NiFe]-hydrogenase diversity, mechanism, and maturation
Peters, J. W., Schut, G. J., Boyd, E. S., Mulder, D. W., Shepard, E. M., Broderick, J. B., King, P. W., & Adams, M. W. W. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.11.021 · Cited by 506 · see citing works
The Importance of Energy Balance in Improving Photosynthetic Productivity
Kramer, D. M., & Evans, J. R. (2011) · Plant Physiology · doi:10.1104/pp.110.166652 · Cited by 494 · see citing works
Systems metabolic engineering of Escherichia coli for L‐threonine production
Lee, K. H., Park, J. H., Kim, T. Y., Kim, H. U., & Lee, S. Y. (2007) · Molecular Systems Biology · doi:10.1038/msb4100196 · Cited by 488 · see citing works
Laursen, A. B., Patraju, K., Whitaker, M. J., Retuerto, M., Sarkar, T., Yao, N., Ramanujachary, K. V., Greenblatt, M., & Dismukes, G. C. (2015) · Energy & Environmental Science · doi:10.1039/c4ee02940b · Cited by 482 · see citing works
Self-citationExpanding the solar spectrum used by photosynthesis
Chen, M., & Blankenship, R. E. (2011) · Trends in Plant Science · doi:10.1016/j.tplants.2011.03.011 · Cited by 417 · see citing works
Posewitz, M. C., King, P. W., Smolinski, S. L., Zhang, L., Seibert, M., & Ghirardi, M. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403206200 · Cited by 416 · see citing works
Nitrogen fixation and hydrogen metabolism in cyanobacteria
Bothe, H., Schmitz, O., Yates, M. G., & Newton, W. E. (2010) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00033-10 · Cited by 416 · see citing works
Berman‐Frank, I., Lundgren, P., Chen, Y., Küpper, H., Kolber, Z., Bergman, B., & Falkowski, P. G. (2001) · Science · doi:10.1126/science.1064082 · Cited by 396 · see citing works
Yu, J., Liberton, M., Cliften, P. F., Head, R. D., Jacobs, J., Smith, R. D., Koppenaal, D., Brand, J. J., & Pakrasi, H. B. (2015) · Scientific Reports · doi:10.1038/srep08132 · Cited by 372 · see citing works
Hydrogenases and Hydrogen Photoproduction in Oxygenic Photosynthetic Organisms
Ghirardi, M. L., Posewitz, M. C., Maness, P., Dubini, A., Yu, J., & Seibert, M. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.58.032806.103848 · Cited by 371 · see citing works
Cyanobacterial hydrogenases: diversity, regulation and applications
Tamagnini, P., Leitão, E., Oliveira, P., Ferreira, D., Pinto, F., Harris, D. J., Heidorn, T., & Lindblad, P. (2007) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2007.00085.x · Cited by 367 · see citing works
Böck, A., King, P. W., Blokesch, M., & Posewitz, M. C. (2006) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/s0065-2911(06)51001-x · Cited by 353 · see citing works
Montet, Y., Amara, P., Volbeda, A., Vernède, X., Hatchikian, E. C., Field, M. J., Frey, M., & Fontecilla-Camps, J. C. (1997) · Nature Structural Biology · doi:10.1038/nsb0797-523 · Cited by 343 · see citing works
Optimizing antenna size to maximize photosynthetic efficiency.
Ort, D. R., Zhu, X., (朱新广), & Melis, A. (2011) · Plant Physiology · doi:10.1104/pp.110.165886 · Cited by 338 · see citing works
Metabolic engineering of cyanobacteria for ethanol production
Dexter, J., & Fu, P. (2009) · Energy & Environmental Science · doi:10.1039/b811937f · Cited by 329 · see citing works
Photosynthesis: a blueprint for solar energy capture and biohydrogen production technologies
Kruse, O., Rupprecht, J., Mussgnug, J. H., Dismukes, G. C., & Hankamer, B. D. (2005) · Photochemical & Photobiological Sciences · doi:10.1039/b506923h · Cited by 327 · see citing works
Self-citationFunctional Studies of [FeFe] Hydrogenase Maturation in an Escherichia coli Biosynthetic System
King, P. W., Posewitz, M. C., Ghirardi, M. L., & Seibert, M. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.6.2163-2172.2006 · Cited by 323 · see citing works
Eisenhut, M., Ruth, W., Haimovich, M., Bauwe, H., Kaplan, A., & Hagemann, M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807043105 · Cited by 317 · see citing works
Hydrogen production by Cyanobacteria
Dutta, D., De, D., Chaudhuri, S., & Bhattacharya, S. K. (2005) · Microbial Cell Factories · doi:10.1186/1475-2859-4-36 · Cited by 314 · see citing works
Synthetic biology of cyanobacteria: unique challenges and opportunities
Berla, B. M., Saha, R., Immethun, C. M., Maranas, C. D., Moon, T. S., & Pakrasi, H. B. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00246 · Cited by 305 · see citing works
Detailing the optimality of photosynthesis in cyanobacteria through systems biology analysis
Nogales, J., Gudmundsson, S., Knight, E. M., Palsson, B. O., & Thiele, I. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1117907109 · Cited by 301 · see citing works
Stal, L. (1997) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(97)00056-9 · Cited by 301 · see citing works
Anderson, S. L., & McIntosh, L. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.9.2761-2767.1991 · Cited by 297 · see citing works
Ogawa, T. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.10.4275 · Cited by 292 · see citing works
Ammonium assimilation in cyanobacteria
Muro-Pastor, M. I., Reyes, J. C., & Florencio, F. J. (2005) · Photosynthesis Research · doi:10.1007/s11120-004-2082-7 · Cited by 287 · see citing works
Genes Encoding A-Type Flavoproteins Are Essential for Photoreduction of O2 in Cyanobacteria
Helman, Y., Tchernov, D., Reinhold, L., Shibata, M., Ogawa, T., Schwarz, R., Ohad, I., & Kaplan, A. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00046-0 · Cited by 283 · see citing works
Gründel, M., Scheunemann, R., Lockau, W., & Zilliges, Y. (2012) · Microbiology · doi:10.1099/mic.0.062950-0 · Cited by 282 · see citing works
Davies, F. K., Work, V. H., Beliaev, A. S., & Posewitz, M. C. (2014) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2014.00021 · Cited by 273 · see citing works
Enzymatic production of biohydrogen
Woodward, J., Orr, M. T., Cordray, K., & Greenbaum, E. (2000) · Nature · doi:10.1038/35016633 · Cited by 269 · see citing works
Prince, R. C., & Kheshgi, H. S. (2005) · Critical Reviews in Microbiology · doi:10.1080/10408410590912961 · Cited by 263 · see citing works
Photosynthetic, respiratory and extracellular electron transport pathways in cyanobacteria
Lea‐Smith, D. J., Bombelli, P., Vasudevan, R., & Howe, C. J. (2015) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2015.10.007 · Cited by 262 · see citing works
Peschek, G. A., Löffelhardt, W., & Schmetterer, G. (1999) · Springer eBooks · doi:10.1007/978-1-4615-4827-0 · Cited by 259 · see citing works
Cyclic electron flow in C3 plants
Joliot, P. A., & Joliot, A. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2006.02.018 · Cited by 257 · see citing works
Insights into [FeFe]-Hydrogenase Structure, Mechanism, and Maturation
Mulder, D. W., Shepard, E. M., Meuser, J. E., Joshi, N., King, P. W., Posewitz, M. C., Broderick, J. B., & Peters, J. W. (2011) · Structure · doi:10.1016/j.str.2011.06.008 · Cited by 249 · see citing works
Cournac, L., Guedeney, G., Peltier, G., & Vignais, P. M. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.6.1737-1746.2003 · Cited by 246 · see citing works
Comparative Analysis of the Primary Transcriptome of Synechocystis sp. PCC 6803
Kopf, M., Klähn, S., Scholz, I., Matthiessen, J. K. F., Hess, W. R., & Voß, B. (2014) · DNA Research · doi:10.1093/dnares/dsu018 · Cited by 242 · see citing works
Photosynthetic nitrate assimilation in cyanobacteria
Flores, E., Frías, J. E., Rubio, L. M., & Antonia Herrero, B. (2005) · Photosynthesis Research · doi:10.1007/s11120-004-5830-9 · Cited by 241 · see citing works
High rates of photobiological H2 production by a cyanobacterium under aerobic conditions
Bandyopadhyay, A., Stöckel, J., Min, H., Sherman, L. A., & Pakrasi, H. B. (2010) · Nature Communications · doi:10.1038/ncomms1139 · Cited by 241 · see citing works
Heterocyst development in Anabaena
Golden, J. W., & Yoon, H. (2003) · Current Opinion in Microbiology · doi:10.1016/j.mib.2003.10.004 · Cited by 234 · see citing works
Kirilovsky, D. L. (2007) · Photosynthesis Research · doi:10.1007/s11120-007-9168-y · Cited by 226 · see citing works
Appel, J., Phunpruch, S., Steinmüller, K., & Schulz, R. (2000) · Archives of Microbiology · doi:10.1007/s002030000139 · Cited by 216 · see citing works
Engineering cyanobacteria to improve photosynthetic production of alka(e)nes
Wang, W., Liu, X., & Lü, X. (2013) · Biotechnology for Biofuels · doi:10.1186/1754-6834-6-69 · Cited by 214 · see citing works
Cooley, J. W., & Vermaas, W. F. J. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.14.4251-4258.2001 · Cited by 214 · see citing works
Burgdorf, T., Lenz, O., Buhrke, T., van der Linden, E., Jones, A. K., Albracht, S. P. J., & Friedrich, B. (2005) · Microbial Physiology · doi:10.1159/000091564 · Cited by 212 · see citing works
Buhrke, T., Lenz, O., Krauß, N., & Friedrich, B. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503260200 · Cited by 212 · see citing works
Flux Balance Analysis of Photoautotrophic Metabolism
Shastri, A. A., & Morgan, J. A. (2005) · Biotechnology Progress · doi:10.1021/bp050246d · Cited by 205 · see citing works
Two Types of Functionally Distinct NAD(P)H Dehydrogenases inSynechocystis sp. Strain PCC6803
Ohkawa, H., Pakrasi, H. B., & Ogawa, T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003706200 · Cited by 203 · see citing works
Hydrogenases: active site puzzles and progress
Armstrong, F. A. (2004) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2004.02.004 · Cited by 195 · see citing works
The Metabolic Network of Synechocystis sp. PCC 6803: Systemic Properties of Autotrophic Growth
Knoop, H., Zilliges, Y., Lockau, W., & Steuer, R. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.157198 · Cited by 195 · see citing works
Yacoby, I., Pochekailov, S., Toporik, H., Ghirardi, M. L., King, P. W., & Zhang, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103659108 · Cited by 193 · see citing works
The physiology and biochemistry of hydrogen metabolism in cyanobacteria
Houchins, J. P. (1984) · Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics · doi:10.1016/0304-4173(84)90018-1 · Cited by 192 · see citing works
Cyanobacterial H2 production ? a comparative analysis
Sch�tz, K., Happe, T., Troshina, O., Lindblad, P., Leit�o, E., Oliveira, P., & Tamagnini, P. (2004) · Planta · doi:10.1007/s00425-003-1113-5 · Cited by 189 · see citing works
Happe, T., Schütz, K., & Böhme, H. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.6.1624-1631.2000 · Cited by 181 · see citing works
Masukawa, M. M. H. (2002) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-002-0934-7 · Cited by 181 · see citing works
Cohen, J., Kim, K., King, P. W., Seibert, M., & Schulten, K. J. (2005) · Structure · doi:10.1016/j.str.2005.05.013 · Cited by 177 · see citing works
Co-existence of photosynthetic and respiratory activities in cyanobacterial thylakoid membranes
Mullineaux, C. W. (2013) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2013.11.017 · Cited by 176 · see citing works
A cyanobacterium that contains chlorophyll f – a red‐absorbing photopigment
Chen, M., Li, Y., Birch, D., & Willows, R. D. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.06.045 · Cited by 175 · see citing works
Biosynthesis of Proteins Incorporating a Versatile Set of Phenylalanine Analogues
Kirshenbaum, K., Carrico, I. S., & Tirrell, D. A. (2002) · ChemBioChem · doi:10.1002/1439-7633(20020301)3:2/3 · Cited by 172 · see citing works
McNeely, K., Xu, Y., Bennette, N., Bryant, D. A., & Dismukes, G. C. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00862-10 · Cited by 168 · see citing works
Self-citationCyanoBase: the cyanobacteria genome database update 2010
Nakao, M., Okamoto, S., Kohara, M., Fujishiro, T., Fujisawa, T., Sato, S., Tabata, S., Kaneko, T., & Nakamura, Y. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp915 · Cited by 166 · see citing works
Schwarz, R., & Grossman, A. R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.11008 · Cited by 165 · see citing works
Hasunuma, T., Kikuyama, F., Matsuda, M., Aikawa, S., Izumi, Y., & Kondo, A. (2013) · Journal of Experimental Botany · doi:10.1093/jxb/ert134 · Cited by 160 · see citing works
Cyanobacterial Oxygenic Photosynthesis is Protected by Flavodiiron Proteins
Allahverdiyeva, Y., Isojärvi, J., Zhang, P., & Aro, E. (2015) · Life · doi:10.3390/life5010716 · Cited by 157 · see citing works
Programmed DNA rearrangement of a cyanobacterial hupL gene in heterocysts.
Carrasco, C. D., Buettner, J. A., & Golden, J. W. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.3.791 · Cited by 154 · see citing works
Mechanism of O2 diffusion and reduction in FeFe hydrogenases
Kubas, A., Orain, C., Sancho, D. D., Saujet, L., Sensi, M., Gauquelin, C., Meynial‐Salles, I., Soucaille, P., Bottin, H., Baffert, C., et al. (2016) · Nature Chemistry · doi:10.1038/nchem.2592 · Cited by 152 · see citing works
Hydrogen production by nitrogen-starved cultures of Anabaena cylindrica
Weissman, J. C., & Benemann, J. R. (1977) · Applied and Environmental Microbiology · doi:10.1128/aem.33.1.123-131.1977 · Cited by 151 · see citing works
High-resolution crystallographic analysis of Desulfovibrio fructosovorans 6NiFe9 hydrogenase
Volbeda, A. (2002) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(02)00072-1 · Cited by 147 · see citing works
Gutekunst, K., Chen, X., Schreiber, K., Kaspar, U., Makam, S. N., & Appel, J. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.526376 · Cited by 139 · see citing works
Ludwig, M., & Bryant, D. A. (2011) · Frontiers in Microbiology · doi:10.3389/fmicb.2011.00041 · Cited by 136 · see citing works
The potential of Synechococcus elongatus UTEX 2973 for sugar feedstock production
Song, K., Tan, X., Liang, Y., & Lü, X. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7510-z · Cited by 135 · see citing works
Steunou, A., Jensen, S. I., Brecht, E., Becraft, E. D., Bateson, M. M., Kilian, O., Bhaya, D., Ward, D. M., Peters, J. W., Grossman, A. R., et al. (2008) · The ISME Journal · doi:10.1038/ismej.2007.117 · Cited by 135 · see citing works
How fast can Photosystem II split water? Kinetic performance at high and low frequencies
Ananyev, G., & Dismukes, G. C. (2005) · Photosynthesis Research · doi:10.1007/s11120-004-7081-1 · Cited by 133 · see citing works
Self-citationThe active site and catalytic mechanism of NiFe hydrogenases
Volbeda, A., & Fontecilla-Camps, J. C. (2003) · Dalton Transactions · doi:10.1039/b304316a · Cited by 133 · see citing works
Production of H2 by the unicellular cyanobacterium Gloeocapsa alpicola CALU 743 during fermentation
Troshina, O. Y. (2002) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(02)00103-9 · Cited by 131 · see citing works
Xu, Y., Guerra, T., Li, Z., Ludwig, M., Dismukes, G. C., & Bryant, D. A. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.12.002 · Cited by 131 · see citing works
Self-citationRewiring hydrogenase-dependent redox circuits in cyanobacteria
Ducat, D. C., Sachdeva, G., & Silver, P. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016026108 · Cited by 130 · see citing works
Murry, M. A., & Wölk, C. P. (1989) · Archives of Microbiology · doi:10.1007/bf00454860 · Cited by 130 · see citing works
Low-Pressure Sorption-Enhanced Hydrogen Production
Yi, K. B., & Harrison, D. P. (2005) · Industrial & Engineering Chemistry Research · doi:10.1021/ie048883g · Cited by 127 · see citing works
Ananyev, G., Carrieri, D., & Dismukes, G. C. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.01078-08 · Cited by 125 · see citing works
Self-citationGutthann, F., Egert, M., Marques, A., & Appel, J. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2006.12.003 · Cited by 124 · see citing works
Xu, Y., Alvey, R. M., Byrne, P. O., Graham, J. E., Shen, G., & Bryant, D. A. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-925-3_21 · Cited by 124 · see citing works
Reconstruction and analysis of genome-scale metabolic model of a photosynthetic bacterium
Montagud, A., Navarro, E., de Córdoba, P. F., Urchueguía, J. F., & Patil, K. R. (2010) · BMC Systems Biology · doi:10.1186/1752-0509-4-156 · Cited by 121 · see citing works
Lea‐Smith, D. J., Ross, N., Zori, M., Bendall, D. S., Dennis, J. S., Scott, S. A., Smith, A. G., & Howe, C. J. (2013) · PLANT PHYSIOLOGY · doi:10.1104/pp.112.210260 · Cited by 121 · see citing works
Photosynthesis in flashing light
Kok, B. (1956) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(56)90004-x · Cited by 117 · see citing works
Introduction of Methionines in the Gas Channel Makes [NiFe] Hydrogenase Aero-Tolerant
Dementin, S., Leroux, F., Cournac, L., Lacey, A. L. D., Volbeda, A., Léger, C., Burlat, B., Martínez, N., Champ, S., Martin, L., et al. (2009) · Journal of the American Chemical Society · doi:10.1021/ja9018258 · Cited by 115 · see citing works
Cell‐free synthesis and maturation of [FeFe] hydrogenases
Boyer, M. E., Stapleton, J. A., Kuchenreuther, J. M., Wang, C., & Swartz, J. R. (2007) · Biotechnology and Bioengineering · doi:10.1002/bit.21511 · Cited by 114 · see citing works
Baebprasert, W., Jantaro, S., Khetkorn, W., Lindblad, P. C., & Incharoensakdi, A. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.07.004 · Cited by 112 · see citing works
The role of the bidirectional hydrogenase in cyanobacteria
Carrieri, D., Wawrousek, K., Eckert, C. A., Yu, J., & Maness, P. (2011) · Bioresource Technology · doi:10.1016/j.biortech.2011.03.103 · Cited by 112 · see citing works
A high resolution map of a cyanobacterial transcriptome
Vijayan, V., Jain, I. H., & O’Shea, E. K. (2011) · Genome biology · doi:10.1186/gb-2011-12-5-r47 · Cited by 107 · see citing works
Yoshino, F., Ikeda, H., Masukawa, H., & Sakurai, H. (2006) · Marine Biotechnology · doi:10.1007/s10126-006-6035-3 · Cited by 106 · see citing works
Stiebritz, M. T., & Reiher, M. (2012) · Chemical Science · doi:10.1039/c2sc01112c · Cited by 106 · see citing works
Cyanobacterial chassis engineering for enhancing production of biofuels and chemicals
Gao, X., Sun, T., Pei, G., Chen, L., & Zhang, W. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7374-2 · Cited by 106 · see citing works
McIntosh, C. L., Germer, F., Schulz, R., Appel, J., & Jones, A. K. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203376y · Cited by 104 · see citing works
Liebgott, P.-P., Lacey, A. L. D., Burlat, B., Cournac, L., Richaud, P., Brugna, M., Fernández, V. M., Guigliarelli, B., Rousset, M., Léger, C., et al. (2010) · Journal of the American Chemical Society · doi:10.1021/ja108787s · Cited by 103 · see citing works
Eilenberg, H., Weiner, I. N., Ben‐Zvi, O., Pundak, C., Marmari, A., Liran, O., Wecker, M. S. A., Milrad, Y., & Yacoby, I. (2016) · Biotechnology for Biofuels · doi:10.1186/s13068-016-0601-3 · Cited by 98 · see citing works
Sveshnikov, D., Sveshnikova, N., Rao, K. K., & Hall, D. O. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1997.tb10257.x · Cited by 97 · see citing works
Hendry, J. I., Prasannan, C. B., Joshi, A. A., Dasgupta, S., & Wangikar, P. P. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.02.128 · Cited by 94 · see citing works
Saha, R., Verseput, A. T., Berla, B. M., Mueller, T. J., Pakrasi, H. B., & Maranas, C. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048285 · Cited by 93 · see citing works
Stapleton, J. A., & Swartz, J. R. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015275 · Cited by 91 · see citing works
Carrieri, D., Momot, D., Brasg, I. A., Ananyev, G., Lenz, O., Bryant, D. A., & Dismukes, G. C. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00975-10 · Cited by 91 · see citing works
Self-citationCyanobacteria as Chassis for Industrial Biotechnology: Progress and Prospects
Al‐Haj, L., Lui, Y. T., Abed, R. M. M., Gomaa, M., & Purton, S. (2016) · Life · doi:10.3390/life6040042 · Cited by 90 · see citing works
Tel‐Or, E., & Stewart, W. D. P. (1977) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1977.0086 · Cited by 89 · see citing works
The respiratory chain of blue‐green algae (cyanobacteria)
Peschek, G. A., Obinger, C., & Paumann, M. (2004) · Physiologia Plantarum · doi:10.1111/j.1399-3054.2004.00274.x · Cited by 89 · see citing works
A hydrogen-producing, hydrogenase-free mutant strain of Nostoc punctiforme ATCC 29133
Lindberg, P. (2002) · International Journal of Hydrogen Energy · doi:10.1016/s0360-3199(02)00121-0 · Cited by 88 · see citing works
Cyanobacteria contain a mitochrondrial complex I‐homologous NADH‐dehydrogenase
Berger, S., Ellersiek, U., & Steinmüller, K. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80957-5 · Cited by 88 · see citing works
Vu, T. T., Stolyar, S. M., Pinchuk, G. E., Hill, E. A., Kucek, L. A., Brown, R. N., Lipton, M. S. W., Osterman, A. L., Fredrickson, J. K., Konopka, A. E., et al. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002460 · Cited by 86 · see citing works
Fermentation and Sulfur Reduction in the Mat-Building Cyanobacterium Microcoleus chthonoplastes
Moezelaar, R., Bijvank, S., & Stal, L. J. (1996) · Applied and Environmental Microbiology · doi:10.1128/aem.62.5.1752-1758.1996 · Cited by 86 · see citing works
Duché, O., Elsen, S., Cournac, L., & Colbeau, A. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04806.x · Cited by 86 · see citing works
van Thor, J. J., Jeanjean, R., Havaux, M., Sjollema, K. A., Joset, F., Hellingwerf, K. J., & Matthijs, H. C. P. (2000) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00072-4 · Cited by 86 · see citing works
Heterologous expression of clostridial hydrogenase in the cyanobacterium Synechococcus PCC7942
Asada, Y., Koike, Y., Schnackenberg, J., Miyake, M., Uemura, I., & Miyake, J. (2000) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(00)00010-5 · Cited by 82 · see citing works
Adamson, H., Robinson, M. J., Wright, J. J., Flanagan, L. A., Walton, J., Elton, D. M., Gavaghan, D. J., Bond, A. M., Roessler, M. M., & Parkin, A. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b03611 · Cited by 82 · see citing works
Recent Applications of Metabolomics Toward Cyanobacteria
Schwarz, D., Orf, I., Kopka, J., & Hagemann, M. (2013) · Metabolites · doi:10.3390/metabo3010072 · Cited by 80 · see citing works
Hickman, J. W., Kotovic, K. M., Miller, C. R., Warrener, P., Kaiser, B. K., Jurista, T., Budde, M. W., Cross, F., Roberts, J. M., & Carleton, M. O. (2013) · Algal Research · doi:10.1016/j.algal.2013.01.008 · Cited by 79 · see citing works
Ludwig, M., Schulz‐Friedrich, R., & Appel, J. (2006) · Journal of Molecular Evolution · doi:10.1007/s00239-006-0001-6 · Cited by 78 · see citing works
Terminal oxidases of cyanobacteria
Hart, S. E., Schlarb‐Ridley, B. G., Bendall, D. S., & Howe, C. J. (2005) · Biochemical Society Transactions · doi:10.1042/bst0330832 · Cited by 76 · see citing works
The quest for a functional substrate access tunnel in FeFe hydrogenase
Lautier, T., Ezanno, P., Baffert, C., Fourmond, V., Cournac, L., Fontecilla-Camps, J. C., Soucaille, P., Bertrand, P., Meynial‐Salles, I., & Léger, C. (2010) · Faraday Discussions · doi:10.1039/c004099c · Cited by 76 · see citing works
Cai, Y. A., Murphy, J. T., Wedemayer, G. J., & Glazer, A. N. (2001) · Analytical Biochemistry · doi:10.1006/abio.2000.4979 · Cited by 76 · see citing works
Huesemann, M. H., Hausmann, T. S., Carter, B. M., Gerschler, J. J., & Benemann, J. R. (2009) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-009-8741-6 · Cited by 72 · see citing works
Tyrosine, Cysteine, and S-Adenosyl Methionine Stimulate In Vitro [FeFe] Hydrogenase Activation
Kuchenreuther, J. M., Stapleton, J. A., & Swartz, J. R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007565 · Cited by 72 · see citing works
Engineered Transcriptional Systems for Cyanobacterial Biotechnology
Camsund, D., & Lindblad, P. (2014) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2014.00040 · Cited by 70 · see citing works
Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803
Yoshikawa, K., Kojima, Y., Nakajima, T., Furusawa, C., Hirasawa, T., & Shimizu, H. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3559-x · Cited by 70 · see citing works
Transcriptional Regulation of Nostoc Hydrogenases: Effects of Oxygen, Hydrogen, and Nickel
Axelsson, R., & Lindblad, P. C. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.1.444-447.2002 · Cited by 69 · see citing works
Computational evaluation of Synechococcus sp. PCC 7002 metabolism for chemical production
Vu, T. T., Hill, E. A., Kucek, L. A., Konopka, A. E., Beliaev, A. S., & Reed, J. L. (2013) · Biotechnology Journal · doi:10.1002/biot.201200315 · Cited by 67 · see citing works
Hydrogen formation by marine blue—green algae
Lambert, G. R., & SMITH, G. D. (1977) · FEBS Letters · doi:10.1016/0014-5793(77)80664-9 · Cited by 66 · see citing works
Chen, M., Hiller, R. G., Howe, C. J., & Larkum, A. W. D. (2004) · Molecular Biology and Evolution · doi:10.1093/molbev/msh250 · Cited by 65 · see citing works
Irmler, A., Sanner, S., Dierks, H., & Forchhammer, K. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.5521918.x · Cited by 64 · see citing works
Boison, G., Bothe, H., & Schmitz, O. (2000) · Current Microbiology · doi:10.1007/s002849910063 · Cited by 61 · see citing works
Morrison, C. N., Hoy, J. A., Zhang, L., Einsle, O., & Rees, D. C. (2015) · Biochemistry · doi:10.1021/bi501313k · Cited by 60 · see citing works
Nitrogen Fixation in Cyanobacteria
Stal, L. J. (2015) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0021159.pub2 · Cited by 60 · see citing works
Screening for biohydrogen production by cyanobacteria isolated from the Baltic Sea and Finnish lakes
Allahverdiyeva, Y., Leino, H., Saari, L., Fewer, D. P., Shunmugam, S., Sivonen, K., & Aro, E. (2010) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2009.12.030 · Cited by 60 · see citing works
Bernát, G., Waschewski, N., & Rögner, M. (2009) · Photosynthesis Research · doi:10.1007/s11120-008-9398-7 · Cited by 59 · see citing works
Khetkorn, W., Lindblad, P. C., & Incharoensakdi, A. (2012) · Journal of Biological Engineering · doi:10.1186/1754-1611-6-19 · Cited by 59 · see citing works
Hydrogen production in photosynthetic microbial mats in the Elkhorn Slough estuary, Monterey Bay
Burow, L. C., Woebken, D., Bebout, B. M., McMurdie, P. J., Singer, S. W., Pett‐Ridge, J., Prufert‐Bebout, L. E., Spormann, A. M., Weber, P. M., & Hoehler, T. M. (2011) · The ISME Journal · doi:10.1038/ismej.2011.142 · Cited by 57 · see citing works
Rakhimberdieva, M. G., Elanskaya, I. V., Vermaas, W. F. J., & Karapetyan, N. V. (2009) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2009.10.008 · Cited by 56 · see citing works
Salomon, E., Bar-Eyal, L., Sharon, S., & Keren, N. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2012.11.010 · Cited by 56 · see citing works
Baebprasert, W., Lindblad, P. C., & Incharoensakdi, A. (2010) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2010.04.047 · Cited by 56 · see citing works
Kumaraswamy, G. K., Guerra, T., Qian, X., Zhang, S., Bryant, D. A., & Dismukes, G. C. (2013) · Energy & Environmental Science · doi:10.1039/c3ee42206b · Cited by 56 · see citing works
Self-citationHishiya, S., Hatakeyama, W., Mizota, Y., Hosoya‐Matsuda, N., Motohashi, K., Ikeuchi, M., & Hisabori, T. (2007) · Plant and Cell Physiology · doi:10.1093/pcp/pcm158 · Cited by 53 · see citing works
Shimakawa, G., Matsuda, Y., Nakajima, K., Tamoi, M., Shigeoka, S., & Miyake, C. (2017) · Scientific Reports · doi:10.1038/srep41022 · Cited by 51 · see citing works
Maness, P., Smolinski, S. L., Dillon, A. C., Heben, M. J., & Weaver, P. F. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.6.2633-2636.2002 · Cited by 51 · see citing works
Mustila, H., Paananen, P., Battchikova, N., Santana‐Sánchez, A., Muth‐Pawlak, D., Hagemann, M., Aro, E., & Allahverdiyeva, Y. (2016) · Plant and Cell Physiology · doi:10.1093/pcp/pcw047 · Cited by 50 · see citing works
Yoshikawa, K., Toya, Y., & Shimizu, H. (2017) · Bioprocess and Biosystems Engineering · doi:10.1007/s00449-017-1744-8 · Cited by 50 · see citing works
Skizim, N. J., Ananyev, G., Krishnan, A., & Dismukes, G. C. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.302125 · Cited by 50 · see citing works
Self-citationi AK692: A genome-scale metabolic model of Spirulina platensis C1
Klanchui, A., Khannapho, C., Phodee, A., Cheevadhanarak, S., & Meechai, A. (2012) · BMC Systems Biology · doi:10.1186/1752-0509-6-71 · Cited by 49 · see citing works
Guerra, T., Xu, Y., Bennette, N. B., McNeely, K., Bryant, D. A., & Dismukes, G. C. (2013) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2013.04.005 · Cited by 47 · see citing works
Self-citationMasukawa, H., Inoue, K., Sakurai, H., Wölk, C. P., & Hausinger, R. P. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.01056-10 · Cited by 47 · see citing works
Qian, X., Kim, M. K., Kumaraswamy, G. K., Agarwal, A., Lun, D. S., & Dismukes, G. C. (2016) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2016.12.007 · Cited by 46 · see citing works
Self-citationRuffing, A. M. (2013) · Journal of Applied Phycology · doi:10.1007/s10811-013-9993-7 · Cited by 45 · see citing works
Knoop, H., & Steuer, R. (2015) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2015.00047 · Cited by 45 · see citing works
Hamilton, J. J., & Reed, J. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034670 · Cited by 45 · see citing works
Klotz, A., Reinhold, E., Doello, S., & Forchhammer, K. (2015) · Life · doi:10.3390/life5010888 · Cited by 45 · see citing works
Choi, S. Y., Park, B., Choi, I., Sim, S. J., Lee, S., Um, Y., & Woo, H. M. (2016) · Scientific Reports · doi:10.1038/srep30584 · Cited by 44 · see citing works
Shah, V., Garg, N., & Madamwar, D. (2001) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(00)00508-5 · Cited by 44 · see citing works
Taikhao, S., Junyapoon, S., Incharoensakdi, A., & Phunpruch, S. (2012) · Journal of Applied Phycology · doi:10.1007/s10811-012-9892-3 · Cited by 43 · see citing works
A substrate channel in the nitrogenase MoFe protein
Barney, B. M., Yurth, M. G., Santos, P. C. D., Dean, D. R., & Seefeldt, L. C. (2009) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-009-0544-2 · Cited by 43 · see citing works
Sulfide‐dependent hydrogen evolution in the cyanobacterium Oscillatoria limnetica
Belkin, S., & Padan, E. (1978) · FEBS Letters · doi:10.1016/0014-5793(78)80959-4 · Cited by 42 · see citing works
Metabolic flux analysis of Cyanothece sp. ATCC 51142 under mixotrophic conditions
Alagesan, S., Gaudana, S. B., Sinha, A., & Wangikar, P. P. (2013) · Photosynthesis Research · doi:10.1007/s11120-013-9911-5 · Cited by 42 · see citing works
Role of HoxE subunit in Synechocystis PCC6803 hydrogenase
Aubert‐Jousset, E., Cano, M., Guedeney, G., Richaud, P., & Cournac, L. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08308.x · Cited by 41 · see citing works
Weyman, P. D., Vargas, W. A., Tong, Y., Yu, J., Maness, P., Smith, H. O., & Xu, Q. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020126 · Cited by 41 · see citing works
Ortega-Ramos, M., Jittawuttipoka, T., Saenkham, P., Kwasiborski, A., Bottin, H., Cassier‐Chauvat, C., & Chauvat, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089372 · Cited by 40 · see citing works
Hydrogen overproducing nitrogenases obtained by random mutagenesis and high-throughput screening
Barahona, E., Jiménez‐Vicente, E., & Rubio, L. M. (2016) · Scientific Reports · doi:10.1038/srep38291 · Cited by 40 · see citing works
Yoshikawa, K., Aikawa, S., Kojima, Y., Toya, Y., Furusawa, C., Kondo, A., & Shimizu, H. (2015) · PLOS ONE · doi:10.1371/journal.pone.0144430 · Cited by 39 · see citing works
Importance of the Active Site “Canopy” Residues in an O2-Tolerant [NiFe]-Hydrogenase
Brooke, E. J., Evans, R. M., Islam, S. T. A., Roberts, G. M., Wehlin, S. A. M., Carr, S. B., Phillips, S. E. V., & Armstrong, F. A. (2016) · Biochemistry · doi:10.1021/acs.biochem.6b00868 · Cited by 38 · see citing works
Oliveira, P., Leitão, E., Tamagnini, P., Moradas‐Ferreira, P., & Oxelfelt, F. (2004) · Microbiology · doi:10.1099/mic.0.27248-0 · Cited by 38 · see citing works
Sustained H 2 Production Driven by Photosynthetic Water Splitting in a Unicellular Cyanobacterium
Melnicki, M. R., Pinchuk, G. E., Hill, E. A., Kucek, L. A., Fredrickson, J. K., Konopka, A. E., & Beliaev, A. S. (2012) · mBio · doi:10.1128/mbio.00197-12 · Cited by 36 · see citing works
Maróti, G., Tong, Y., Yooseph, S., Baden-Tillson, H., Smith, H. O., Kovács, K. L., Frazier, M. E., Venter, J. C., & Xu, Q. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.00580-09 · Cited by 36 · see citing works
Sakurai, H., Masukawa, H., Kitashima, M., & Inoue, K. (2015) · Life · doi:10.3390/life5010997 · Cited by 35 · see citing works
Hydrogen evolution from immobilized cultures of the cyanobacterium Anabaena cylindrica B629
Lambert, G. R., Daday, A., & Smith, G. D. (1979) · FEBS Letters · doi:10.1016/0014-5793(79)81309-5 · Cited by 35 · see citing works
Imashimizu, M., Bernát, G., Sunamura, E.-I., Broekmans, M., Konno, H., 耕太, 伊., Rögner, M., & Hisabori, T. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.234138 · Cited by 34 · see citing works
Vargas, W. A., Weyman, P. D., Tong, Y., Smith, H. O., & Xu, Q. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.01559-10 · Cited by 34 · see citing works
Extremophilic Cyanobacteria For Novel Drug Development
Mandal, S., & Rath, J. (2014) · SpringerBriefs in pharmaceutical science & drug development · doi:10.1007/978-3-319-12009-6 · Cited by 34 · see citing works
Enhancing biological hydrogen production from cyanobacteria by removal of excreted products
Ananyev, G., Skizim, N. J., & Dismukes, G. C. (2012) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2012.03.026 · Cited by 33 · see citing works
Self-citationBerto, P., D’Adamo, S., Bergantino, E., Vallese, F., Giacometti, G. M., & Costantini, P. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.01.095 · Cited by 33 · see citing works
Wecker, M. S. A., Meuser, J. E., Posewitz, M. C., & Ghirardi, M. L. (2011) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2011.05.121 · Cited by 33 · see citing works
Alpes, I., Scherer, S., & Böger, P. (1989) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(89)80400-1 · Cited by 33 · see citing works
Navarro, F., Martı́n-Figueroa, E., Candau, P., & Florencio, F. J. (2000) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2000.1894 · Cited by 32 · see citing works
Wang, X., Xiong, X., Sa, N., Roje, S., & Chen, S. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7521-9 · Cited by 32 · see citing works
Microsensor measurements of hydrogen gas dynamics in cyanobacterial microbial mats
Nielsen, M., Revsbech, N. P., & Kühl, M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00726 · Cited by 32 · see citing works
Katsuda, T., Ooshima, H., Azuma, M., & Kato, J. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.102.220 · Cited by 31 · see citing works
Masukawa, H., Sakurai, H., Hausinger, R. P., & Inoue, K. (2017) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-8078-3 · Cited by 31 · see citing works
Expression of Shewanella oneidensis MR-1 [FeFe]-Hydrogenase Genes in Anabaena sp. Strain PCC 7120
Gärtner, K., Lechno‐Yossef, S., Cornish, A. J., Wölk, C. P., & Hegg, E. L. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.01959-12 · Cited by 30 · see citing works
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Progress and prospects of hydrogen production: Opportunities and challenges
Zhang, B., Zhang, S., Yao, R. Q., Wu, Y.-H., & Qiu, J. (2021) · Journal of Electronic Science and Technology · doi:10.1016/j.jnlest.2021.100080 · Cited by 256 · see citing works
Microalgae: The Future Supply House of Biohydrogen and Biogas
Wang, K., Khoo, K. S., Chew, K. W., Selvarajoo, A., Chen, W.-H., Chang, J.-S., & Show, P. L. (2021) · Frontiers in Energy Research · doi:10.3389/fenrg.2021.660399 · Cited by 119 · see citing works
RetractedMicroalgal Hydrogen Production
Wang, Y., Yang, H., Zhang, X., Han, F., Tu, W., & Yang, W. (2020) · Small Methods · doi:10.1002/smtd.201900514 · Cited by 101 · see citing works
Algae-Bacteria Consortia as a Strategy to Enhance H2 Production
Fakhimi, N., González-Ballester, D., Fernández, E. M., Galván, A., & Dubini, A. (2020) · Cells · doi:10.3390/cells9061353 · Cited by 87 · see citing works
Kamshybayeva, G. K., Kossalbayev, B. D., Sadvakasova, A. K., Kakimova, A. B., Bauenova, M. O., Zayadan, B. K., Lan, C.-W., Alwasel, S. H., Tomo, T., Chang, J., et al. (2023) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2022.12.342 · Cited by 44 · see citing works
Jaramillo, A., Satta, A., Pinto, F., Faraloni, C., Zittelli, G. C., Benavides, A. M. S., Torzillo, G., Schumann, C., Méndez, J. F., Berggren, G., et al. (2025) · Energy & Fuels · doi:10.1021/acs.energyfuels.4c04772 · Cited by 40 · see citing works
Heterologous Hydrogenase Overproduction Systems for Biotechnology—An Overview
Fan, Q., Neubauer, P. B., Lenz, O., & Gimpel, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165890 · Cited by 39 · see citing works
Rewiring cyanobacterial photosynthesis by the implementation of an oxygen-tolerant hydrogenase
Lupacchini, S., Appel, J., Stauder, R., Bolay, P., Klähn, S., Lettau, E., Adrian, L., Lauterbach, L., Bühler, B., Schmid, A., et al. (2021) · Metabolic Engineering · doi:10.1016/j.ymben.2021.10.006 · Cited by 35 · see citing works
Sustainable production of algae-bacteria granular consortia based biological hydrogen: New insights
Giri, D. D., Dwivedi, H., Alsukaibi, A. K. D., Pal, D. B., Otaibi, A. A., Areeshi, M. Y., Haque, S., & Gupta, V. K. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.127036 · Cited by 32 · see citing works
Progress and innovation in key technologies for converting biomass to hydrogen
Kamshybayeva, G. K., Sadvakasova, A. K., MARATOVICH, B. A., Kossalbayev, B. D., Bauenova, M. O., Zharmukhamedov, S. K., Hou, H. J. M., & Allakhverdiev, S. I. (2025) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2025.02.437 · Cited by 21 · see citing works
Misztak, A. E., Waleron, M., Furmaniak, M., Waleron, M. M., Bazhenova, O., Daroch, M., & Waleron, K. F. (2021) · Cells · doi:10.3390/cells10123411 · Cited by 19 · see citing works
Toepel, J., Karande, R., Bühler, B., Bühler, K., & Schmid, A. (2023) · Bioresource Technology · doi:10.1016/j.biortech.2023.128703 · Cited by 18 · see citing works
Kumaraswamy, K. G., Krishnan, A., Ananyev, G., Zhang, S., Bryant, D. A., & Dismukes, G. C. (2019) · Energy & Environmental Science · doi:10.1039/c8ee03606c · Cited by 16 · see citing works
Self-citationThe Draft Genome of a Hydrogen-producing Cyanobacterium, <i>Arthrospira platensis</i> NIES-46
Suzuki, S., Yamaguchi, H., & Kawachi, M. (2019) · Journal of Genomics · doi:10.7150/jgen.38149 · Cited by 12 · see citing works
“In particular, Arthrospira maxima is one of the most efficient hydrogen-producing cyanobacterium [4,5], and Arthrospira platensis also produces large amounts of hydrogen [6].”
BackgroundNawaz, T., Fahad, S., Saud, S., Zhou, R., Abdelsalam, N. R., Abdelhamid, M. M. A., & Jaremko, M. (2024) · Current Plant Biology · doi:10.1016/j.cpb.2024.100399 · Cited by 8 · see citing works
De novo synthesis of synthetic biology ecosystem in Slovakia: Challenges and opportunities
Gašpárek, M., & Hantabal, J. (2022) · Biotechnology Notes · doi:10.1016/j.biotno.2022.06.001 · Cited by 5 · see citing works
Cultivating Limnospira fusiformis from Lake Solenoye, Omsk
Молибога, Е. А., & Bazhenova, O. P. (2023) · Food Processing Techniques and Technology · doi:10.21603/2074-9414-2023-4-2469 · Cited by 2 · see citing works
Bioproduction from Microalgal Resources
Iwata, O., & Mochida, K. (2020) · Springer eBooks · doi:10.1007/978-981-15-5228-1_8
Limnospira fusiformis from Lake Solenoe, Omsk: Rationalizing Marketing and Research
Молибога, Е. А., & Викторовна, Л. В. (2024) · Food Processing Techniques and Technology · doi:10.21603/2074-9414-2024-4-2545
Effects of Photosynthesis Inhibitors on H2 Production in Microalgae and Cyanobacteria
Kirbayeva, D. K., Sadvakasova, A. K., Botbayev, D. M., Bauenova, M. O., Zaletova, D. E., MARATOVICH, B. A., Abseyt, А. S., Ahmad, F., & Kossalbayev, B. D. (2026) · Plants · doi:10.3390/plants15132012
- Authors
- Krishnan, A., Qian, X., Ananyev, G., Lun, D. S., & Dismukes, G. C.
- Affiliations
- University of Alberta (CA)
- Rutgers, The State University of New Jersey (US)
- Corresponding author
- Dismukes, G. Charles
- Venue
- Advances in Experimental Medicine and Biology
- Publisher
- Springer Singapore
- Published
- 2018
- Volume
- 1080
- Pages
- 171-213
- ISSN
- 0065-2598 (ISSN-L)
- 2214-8019
- OpenAlex
- W2886991948
- Cited by
- 20
- References
- 231
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 2
- FWCI
- 3.37
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Advances in experimental medicine and biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Metalloenzymes and iron-sulfur proteins
- Keywords
- cyanobacteria, hydrogen production, metabolic engineering, synthetic biology, nitrogenase, bidirectional hydrogenase, photocatalytic water splitting, chassis organisms
- MeSH terms
- Cyanobacteria, Hydrogen, Synthetic Biology, Metabolic Engineering
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