The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic membrane of target cells
Open accessAbstract
Pediocin PA-1 is a bacteriocin which is produced by Pediococcus acidilactici PAC1.0. We demonstrate that pediocin PA-1 kills sensitive Pediococcus cells and acts on the cytoplasmic membrane. In contrast to its lack of impact on immune cells, pediocin PA-1 dissipates the transmembrane electrical potential and inhibits amino acid transport in sensitive cells. Pediocin interferes with the uptake of amino acids by cytoplasmic membrane vesicles derived from sensitive cells, while it is less effective with membranes derived from immune cells. In liposomes fused with membrane vesicles derived from both sensitive and immune cells, pediocin PA-1 elicits an efflux of small ions and, at higher concentrations, an efflux of molecules having molecular weights of up to 9,400. Our data suggest that pediocin PA-1 functions in a voltage-independent manner but requires a specific protein in the target membrane.
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Bacteriocins: safe, natural antimicrobials for food preservation.
Cleveland, J., Montville, T. J., Nes, I. F., & Chikindas, M. L. (2001) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(01)00560-8 · Cited by 1,835
Self-citationAntimicrobial Peptides: An Update on Classifications and Databases
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Pediocin PA-1, a Wide-Spectrum Bacteriocin from Lactic Acid Bacteria
Rodríguez, J. M., Martínez, M. I., & Kok, J. (2002) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408690290825475 · Cited by 301
Metadata
- Authors
- Chikindas, M. L., García-Garcerá, M. J., Driessen, A. J., Ledeboer, A. M., Nissen-Meyer, J., Nes, I. F., Abee, T., Konings, W. N., & Venema, G.
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1993-11
- Volume
- 59
- Issue
- 11
- Pages
- 3577-3584
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- OpenAlex
- W1860407554
- Cited by
- 266
- References
- 43
- FWCI
- 20.71
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Chikindas, M. L., García-Garcerá, M. J., Driessen, A. J., Ledeboer, A. M., Nissen-Meyer, J., Nes, I. F., Abee, T., Konings, W. N., & Venema, G. (1993). Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic membrane of target cells. Applied and Environmental Microbiology. https://doi.org/10.1128/aem.59.11.3577-3584.1993
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