Antimicrobial heteroresistance: An emerging field in need of clarity

Bacterial biofilms: from the Natural environment to infectious diseases

Hall‐Stoodley, L., Costerton, J. W., & Stoodley, P. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro821 · Cited by 7,133 · see citing works

Antibiotic resistance threats in the United States, 2019

(U.S.), C. F. D. C. A. P. (2019) · doi:10.15620/cdc:82532 · Cited by 5,782 · see citing works

Physiological heterogeneity in biofilms

Stewart, P. S., & Franklin, M. J. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1838 · Cited by 2,480 · see citing works

Molecular Mechanisms of Antibacterial Multidrug Resistance

Alekshun, M. N., & Levy, S. B. (2007) · Cell · doi:10.1016/j.cell.2007.03.004 · Cited by 1,648 · see citing works

Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis

Gibson, R. L., Burns, J. L., & Ramsey, B. W. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200304-505so · Cited by 1,629 · see citing works

Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin

Hiramatsu, K., Aritaka, N., Hanaki, H., Kawasaki, S., Hosoda, Y., Hori, S., Fukuchi, Y., & Kobayashi, I. (1997) · The Lancet · doi:10.1016/s0140-6736(97)07324-8 · Cited by 1,333 · see citing works

Indole as an intercellular signal in microbial communities

Lee, J.-H., & Lee, J. (2010) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2009.00204.x · Cited by 1,059 · see citing works

Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation

Drenkard, E., & Ausubel, F. M. (2002) · Nature · doi:10.1038/416740a · Cited by 997 · see citing works

ENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON

Novick, A., & Weiner, M. (1957) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.43.7.553 · Cited by 891 · see citing works

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

Moffatt, J. H., Harper, M., Harrison, P. F., Hale, J. D. F., VINOGRADOV, E. V., Seemann, T., Henry, R., Crane, B., Michael, F. S., Cox, A. D., et al. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00834-10 · Cited by 817 · see citing works

Bacterial charity work leads to population-wide resistance

Lee, H. H., Molla, M. N., Cantor, C. R., & Collins, J. J. (2010) · Nature · doi:10.1038/nature09354 · Cited by 638 · see citing works

Cannibalism by sporulating bacteria.

González-Pastor, J. E., Hobbs, E. C., & Losick, R. (2003) · Science · doi:10.1126/science.1086462 · Cited by 579 · see citing works

Heteroresistance to Colistin in Multidrug-Resistant Acinetobacter baumannii

Li, J., Rayner, C. R., Nation, R. L., Owen, R. J., Spelman, D., Tan, K. E., & Liolios, L. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00103-06 · Cited by 549 · see citing works

Non-genetic individuality: chance in the single cell

Spudich, J. L., & Koshland, D. E. (1976) · Nature · doi:10.1038/262467a0 · Cited by 522 · see citing works

Clinical Features Associated with Bacteremia Due to Heterogeneous Vancomycin‐IntermediateStaphylococcus aureus

Charles, P. G. P., Ward, P. B., Johnson, P. D. R., Howden, B. P., & Grayson, M. L. (2004) · Clinical Infectious Diseases · doi:10.1086/381093 · Cited by 384 · see citing works

THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS

Eagle, H., & Musselman, A. D. (1948) · The Journal of Experimental Medicine · doi:10.1084/jem.88.1.99 · Cited by 378 · see citing works

Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR

Howden, B. P., McEvoy, C. R. E., Allen, D. L., Chua, K., Gao, W., Harrison, P. F., Bell, J. M., Coombs, G. W., Bennett-Wood, V. R., Porter, J. L., et al. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002359 · Cited by 371 · see citing works

Centers for Disease Control and Prevention. 2013. Strategies to Prevent Obesity and Other Chronic Diseases: The CDC Guide to Strategies to Support Breastfeeding Mothers and Babies. Atlanta, GA: U.S. Department of Health and Human Services, 2013

McGuire, S. (2014) · Advances in Nutrition · doi:10.3945/an.114.005900 · Cited by 365 · see citing works

Accessory Gene Regulator ( agr ) Locus in Geographically Diverse Staphylococcus aureus Isolates with Reduced Susceptibility to Vancomycin

Sakoulas, G., Eliopoulos, G. M., Moellering, R. C., Wennersten, C. B., Venkataraman, L., Novick, R. P., & Gold, H. S. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.5.1492-1502.2002 · Cited by 364 · see citing works

The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress

Gefen, O., & Balaban, N. Q. (2009) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2008.00156.x · Cited by 313 · see citing works

Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus

Hartman, B. J., & Tomasz, A. (1986) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.29.1.85 · Cited by 265 · see citing works

Induction of Daptomycin Heterogeneous Susceptibility in Staphylococcus aureus by Exposure to Vancomycin

Sakoulas, G., Alder, J. D., Thauvin-Eliopoulos, C., Moellering, R. C., & Eliopoulos, G. M. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.4.1581-1585.2006 · Cited by 262 · see citing works

Keloids: Pathophysiology and management

Robles, D. T., Moore, E. C., Draznin, M., & Berg, D. (2007) · Dermatology Online Journal · doi:10.5070/d32m43548r · Cited by 248 · see citing works

New strategies for combating multidrug-resistant bacteria

Wright, G. D., & Sutherland, A. D. (2007) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2007.04.004 · Cited by 244 · see citing works

Comparative Evaluation of the VITEK 2, Disk Diffusion, Etest, Broth Microdilution, and Agar Dilution Susceptibility Testing Methods for Colistin in Clinical Isolates, Including Heteroresistant <i>Enterobacter cloacae</i> and <i>Acinetobacter baumannii</i> Strains

Lo-Ten-Foe, J. R., de Smet, A. M. G. A., Diederen, B. M. W., Kluytmans, J. A. J. W., & van Keulen, P. H. J. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01406-06 · Cited by 242 · see citing works

Sigma-B, a putative operon encoding alternate sigma factor of Staphylococcus aureus RNA polymerase: molecular cloning and DNA sequencing

Wu, S., de LENCASTRE, H., & Tomasz, A. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.20.6036-6042.1996 · Cited by 241 · see citing works

An RpoB Mutation Confers Dual Heteroresistance to Daptomycin and Vancomycin in Staphylococcus aureus

Cui, L., Isii, T., Fukuda, M., Ochiai, T., Neoh, H., Camargo, I. L. B. D. C., Watanabe, Y., Shoji, M., Hishinuma, T., & Hiramatsu, K. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00437-10 · Cited by 207 · see citing works

Insertion Sequence IS Aba11 Is Involved in Colistin Resistance and Loss of Lipopolysaccharide in Acinetobacter baumannii

Moffatt, J. H., Harper, M., Adler, B., et al. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01732-10 · Cited by 199 · see citing works

Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance

Vega, N. M., Allison, K. R., Samuels, A. N., Klempner, M. S., & Collins, J. J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1308085110 · Cited by 185 · see citing works

Colistin Heteroresistance in Acinetobacter and Its Association with Previous Colistin Therapy

Hawley, J. S., Murray, C. K., & Jorgensen, J. H. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00766-07 · Cited by 183 · see citing works

Bacteremia Caused by Staphylococci with Inducible Vancomycin Heteroresistance

Wong, S. S. Y., Ho, P., Woo, P. C. Y., & Yuen, K. (1999) · Clinical Infectious Diseases · doi:10.1086/520429 · Cited by 165 · see citing works

CHARACTERISTICS OF METHICILLIN-RESISTANT STAPHYLOCOCCI

Sutherland, R., & Rolinson, G. N. (1964) · Journal of Bacteriology · doi:10.1128/jb.87.4.887-899.1964 · Cited by 159 · see citing works

Metronidazole Resistance in Clostridium difficile Is Heterogeneous

Peláez, T., Cercenado, E., Alcalá, L., Marín, M., Martín, A., Martínez-Alarcón, J., Catalán, P., Sánchez-Somolinos, M., & Bouza, E. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.00524-08 · Cited by 156 · see citing works

Mutated Response Regulator graR Is Responsible for Phenotypic Conversion of Staphylococcus aureus from Heterogeneous Vancomycin-Intermediate Resistance to Vancomycin-Intermediate Resistance

Neoh, H., Cui, L., Yuzawa, H., Takeuchi, F., Matsuo, M., & Hiramatsu, K. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00534-07 · Cited by 156 · see citing works

Vancomycin MIC plus Heteroresistance and Outcome of Methicillin-Resistant Staphylococcus aureus Bacteremia: Trends over 11 Years

Musta, A. C., RIEDERER, K. M., Shemes, S. P., Chase, P., Jose, J., Johnson, L. B., & Khatib, R. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.02135-08 · Cited by 152 · see citing works

Epigenetic inheritance based evolution of antibiotic resistance in bacteria

Adam, M., Murali, B., Glenn, N. O., & Potter, S. S. (2008) · BMC Evolutionary Biology · doi:10.1186/1471-2148-8-52 · Cited by 149 · see citing works

Colistin heteroresistance in carbapenemase-producing Klebsiella pneumoniae

Meletis, G., Tzampaz, E., Sianou, E., et al. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr007 · Cited by 148 · see citing works

An Outline of the Pattern of Bacterial Generation Times

Powell, E. O. (1958) · Journal of General Microbiology · doi:10.1099/00221287-18-2-382 · Cited by 148 · see citing works

Nongenetic Individuality in the Host–Phage Interaction

Mizrahi, S. P., Gabay, C., Kishony, R., Oppenheim, A. B., & Balaban, N. Q. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060120 · Cited by 144 · see citing works

Mechanisms of heteroresistance in methicillin-resistant Staphylococcus aureus

Ryffel, C., Strässle, A., Kayser, F. H., & Berger‐Bächi, B. (1994) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.38.4.724 · Cited by 140 · see citing works

Heteroresistance: a concern of increasing clinical significance?

Falagas, M. E., Makris, G. C., Dimopoulos, G., & Matthaiou, D. K. (2008) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2007.01912.x · Cited by 134 · see citing works

Mechanisms of heteroresistance to isoniazid and rifampin of Mycobacterium tuberculosis in Tashkent, Uzbekistan

Hofmann-Thiel, S., van Ingen, J., Feldmann, K., Turaev, L., Uzakova, G., Murmusaeva, G., van Soolingen, D., & Hoffmann, H. (2008) · European Respiratory Journal · doi:10.1183/09031936.00089808 · Cited by 131 · see citing works

Hopanoid Production Is Required for Low-pH Tolerance, Antimicrobial Resistance, and Motility in Burkholderia cenocepacia

Schmerk, C. L., Bernards, M. A., & Valvano, M. A. (2011) · Journal of Bacteriology · doi:10.1128/jb.05979-11 · Cited by 125 · see citing works

Heterogeneous Vancomycin‐Intermediate Susceptibility Phenotype in Bloodstream Methicillin‐Resistant<i>Staphylococcus aureus</i>Isolates from an International Cohort of Patients with Infective Endocarditis: Prevalence, Genotype, and Clinical Significance

Bae, I., Federspiel, J. J., Miró, J. M., Woods, C. W., Park, L., Rybak, M. J., Rude, T. H., Bradley, S., Bukovski, S., de la Maria, C. G., et al. (2009) · The Journal of Infectious Diseases · doi:10.1086/606027 · Cited by 122 · see citing works

Selection of colistin-resistant Acinetobacter baumannii isolates in postneurosurgical meningitis in an intensive care unit with high presence of heteroresistance to colistin

Rodríguez, C. H., Bombicino, K. A., Granados, G., Nastro, M., Carlos, V., & Angela, F. (2009) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.05.019 · Cited by 116 · see citing works

Heterogeneous resistance to vancomycin in Staphylococcus epidermidis, Staphylococcus haemolyticus and Staphylococcus warneri clinical strains: characterisation of glycopeptide susceptibility profiles and cell wall thickening

Nunes, A. P. F., TEIXEIRA, L., Iorio, N. L. P., et al. (2006) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2005.11.013 · Cited by 113 · see citing works

Influence of Culture Heterogeneity in Cell Surface Charge on Adhesion and Biofilm Formation by Enterococcus faecalis

van Merode, A. E. J., van der Mei, H. C., Busscher, H. J., et al. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.7.2421-2426.2006 · Cited by 113 · see citing works

Heterogeneous Vancomycin Resistance in Methicillin-Resistant Staphylococcus aureus Strains Isolated in a Large Italian Hospital

Marchese, A. E., Balistreri, G., Tonoli, E., Debbia, E. A., & Schito, G. C. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.2.866-869.2000 · Cited by 112 · see citing works

Increased amounts of a novel penicillin-binding protein in a strain of methicillin-resistant Staphylococcus aureus exposed to nafcillin.

Chambers, H. F. “., Hartman, B. J., & Tomasz, A. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111965 · Cited by 110 · see citing works

Comparison of c-Nd:YVO4/YVO4 raman lasers and c-Nd:YVO4 self-Raman lasers

Wan, X. B., Wang, Q. P., Liu, Z., et al. (2011) · Laser Physics · doi:10.1134/s1054660x12010197 · Cited by 101 · see citing works

Mutation of RNA Polymerase β Subunit ( rpoB ) Promotes hVISA-to-VISA Phenotypic Conversion of Strain Mu3

Matsuo, M., Hishinuma, T., Katayama, Y., Cui, L., Kapi, M., & Hiramatsu, K. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00398-11 · Cited by 100 · see citing works

Daptomycin non-susceptibility in vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous-VISA (hVISA): implications for therapy after vancomycin treatment failure

Kelley, P., Gao, W., Ward, P. B., & Howden, B. P. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr066 · Cited by 99 · see citing works

Rifampin Heteroresistance in Mycobacterium tuberculosis Cultures as Detected by Phenotypic and Genotypic Drug Susceptibility Test Methods

Folkvardsen, D. B., Thomsen, V. Ø., Rigouts, L., et al. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.01602-13 · Cited by 98 · see citing works

Evaluation of a New Etest Vancomycin-Teicoplanin Strip for Detection of Glycopeptide-Intermediate Staphylococcus aureus (GISA), in Particular, Heterogeneous GISA

Yusof, A., Engelhardt, A., Karlsson, A., Bylund, L., Vidh, P., Mills, K., Wootton, M., & Walsh, T. R. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.00265-08 · Cited by 97 · see citing works

Effect of NaCl and nafcillin on penicillin-binding protein 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus

Chambers, H. F. “., & Hackbarth, C. J. (1987) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.31.12.1982 · Cited by 96 · see citing works

Mutation in the C-Di-AMP Cyclase dacA Affects Fitness and Resistance of Methicillin Resistant Staphylococcus aureus

Haunreiter, V. D., Holmes, N., Kiefer, P., Christen, P., Patrignani, A., Vorholt, J. A., Berger‐Bächi, B., & Senn, M. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073512 · Cited by 95 · see citing works

Antimicrobial susceptibility and heteroresistance in Chinese Clostridium difficile strains

Huang, H., Weintraub, A., Fang, H., et al. (2010) · Anaerobe · doi:10.1016/j.anaerobe.2010.09.002 · Cited by 95 · see citing works

Chemical Communication of Antibiotic Resistance by a Highly Resistant Subpopulation of Bacterial Cells

El-Halfawy, O. M., & Valvano, M. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068874 · Cited by 89 · see citing works

Irreproducible and Uninterpretable Polymyxin B MICs for Enterobacter cloacae and Enterobacter aerogenes

Landman, D., Salamera, J., & Quale, J. M. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.02129-13 · Cited by 89 · see citing works

Performance of Various Testing Methodologies for Detection of Heteroresistant Vancomycin-Intermediate Staphylococcus aureus in Bloodstream Isolates

van Hal, S. J., Wehrhahn, M. C., Barbagiannakos, T., Mercer, J. L., Chen, D., Paterson, D. L., & Gosbell, I. B. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.02302-10 · Cited by 88 · see citing works

Comparison of ATB Staph, Rapid ATB Staph, Vitek, and E-Test Methods for Detection of Oxacillin Heteroresistance in Staphylococci Possessing mecA

Frebourg, N. B., Nouet, D., Lemée, L., et al. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.1.52-57.1998 · Cited by 85 · see citing works

Modulating Activity of Vancomycin and Daptomycin on the Expression of Autolysis Cell-Wall Turnover and Membrane Charge Genes in hVISA and VISA Strains

Cafiso, V., Bertuccio, T., Spina, D., Purrello, S., Campanile, F., Pietro, C. D., Purrello, M., & Stefani, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029573 · Cited by 84 · see citing works

Relevance of vancomycin-intermediate susceptibility and heteroresistance in methicillin-resistant Staphylococcus aureus bacteraemia

Khatib, R., Jose, J., Musta, A. C., Sharma, M., Fakih, M. G., Johnson, L. B., RIEDERER, K. M., & Shemes, S. P. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr169 · Cited by 81 · see citing works

Vancomycin Heteroresistance Is Associated with Reduced Mortality in ST239 Methicillin-Resistant Staphylococcus aureus Blood Stream Infections

van Hal, S. J., Jones, M., Gosbell, I. B., & Paterson, D. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021217 · Cited by 79 · see citing works

Heterogeneously Vancomycin-Resistant Staphylococcus epidermidis Strain Causing Recurrent Peritonitis in a Dialysis Patient during Vancomycin Therapy

Sieradzki, K., Roberts, R. B., Serur, D. S., Hargrave, J., & Tomasz, A. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.1.39-44.1999 · Cited by 78 · see citing works

Characteristics of Meropenem Heteroresistance in Klebsiella pneumoniae Carbapenemase (KPC)-Producing Clinical Isolates of K. pneumoniae

Pournaras, S., Kristo, I., Vrioni, G., et al. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.02134-09 · Cited by 76 · see citing works

Prevalence and Characteristics of Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Bacteremia in a Tertiary Care Center

Maor‬‏, ‪., Rahav, G., Belausov, N., Ben-David, D., Smollan, G., & Keller, N. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.01262-06 · Cited by 75 · see citing works

Selection of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus by Imipenem

Katayama, Y., Murakami-Kuroda, H., Cui, L., et al. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00834-08 · Cited by 68 · see citing works

Eagle-Type Methicillin Resistance: New Phenotype of High Methicillin Resistance under mec Regulator Gene Control

Kondo, N., Kuwahara‐Arai, K., Murakami-Kuroda, H., Tateda-Suzuki, E., & Hiramatsu, K. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.3.815-824.2001 · Cited by 68 · see citing works

Helicobacter pylori amoxicillin heteroresistance due to point mutations in PBP-1A in isogenic isolates

Matteo, M. J., Granados, G., Olmos, M. A., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkm504 · Cited by 68 · see citing works

Carbapenem Heteroresistance in VIM-1-Producing Klebsiella pneumoniae Isolates Belonging to the Same Clone: Consequences for Routine Susceptibility Testing

Tato, M., Morosini, M. I., García, L. M., et al. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.01130-10 · Cited by 66 · see citing works

Frequency of Reduced Vancomycin Susceptibility and Heterogeneous Subpopulation in Persistent or Recurrent Methicillin-Resistant Staphylococcus aureus Bacteremia

Khosrovaneh, A., RIEDERER, K. M., Saeed, S., Tabriz, M. S., Shah, A. R., Hanna, M., Sharma, M., Johnson, L. B., Fakih, M. G., & Khatib, R. (2004) · Clinical Infectious Diseases · doi:10.1086/383036 · Cited by 65 · see citing works

Retrospective screening for heterogeneous vancomycin resistance in diverse Staphylococcus aureus clones disseminated in French hospitals

Chesneau, O., Morvan, A., & Solh, N. E. (2000) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/45.6.887 · Cited by 65 · see citing works

High Proportion of Heteroresistance in gyrA and gyrB in Fluoroquinolone-Resistant Mycobacterium tuberculosis Clinical Isolates

Eilertson, B., Maruri, F., Blackman, A., Herrera, M., Samuels, D. C., & Sterling, T. R. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02066-13 · Cited by 64 · see citing works

Clinical Isolate of Vancomycin-Heterointermediate Staphylococcus aureus Susceptible to Methicillin and In Vitro Selection of a Vancomycin-Resistant Derivative

Bobin-Dubreux, S., Reverdy, M. E., Nervi, C., Rougier, M., Bolmström, A., Vandenesch, F., & Étienne, J. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.1.349-352.2001 · Cited by 62 · see citing works

Heteroresistance to penicillin in Streptococcus pneumoniae

Morand, B., & Mühlemann, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702377104 · Cited by 61 · see citing works

A Microdilution Plating Method for Population Analysis of Antibiotic-Resistant Staphylococci

Pfeltz, R. F., Schmidt, J. L., & Wilkinson, B. J. (2001) · Microbial Drug Resistance · doi:10.1089/10766290152652846 · Cited by 61 · see citing works

Occurrence of vancomycin-tolerant and heterogeneous vancomycin-intermediate strains (hVISA) among Staphylococcus aureus causing bloodstream infections in nine USA hospitals

Sader, H. S., Jones, R. N., Rossi, K., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp319 · Cited by 61 · see citing works

Heteroresistance at the Single-Cell Level: Adapting to Antibiotic Stress through a Population-Based Strategy and Growth-Controlled Interphenotypic Coordination

Wang, X., Kang, Y., Luo, C., Zhao, T., Liu, L., Jiang, X., Fu, R., An, S., Chen, J., Jiang, N., et al. (2014) · mBio · doi:10.1128/mbio.00942-13 · Cited by 60 · see citing works

Prevalence and Characterization of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Isolates from 14 Cities in China

Sun, W., Chen, H., Liu, Y., et al. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00206-09 · Cited by 60 · see citing works

A Phosphoglucomutase-Like Gene Essential for the Optimal Expression of Methicillin Resistance in Staphylococcus aureus : Molecular Cloning and DNA Sequencing

Wu, S., de LENCASTRE, H., Šali, A., et al. (1996) · Microbial Drug Resistance · doi:10.1089/mdr.1996.2.277 · Cited by 59 · see citing works

Putrescine Reduces Antibiotic-Induced Oxidative Stress as a Mechanism of Modulation of Antibiotic Resistance in Burkholderia cenocepacia

El-Halfawy, O. M., & Valvano, M. A. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02649-14 · Cited by 58 · see citing works

Detection of Intermediately Vancomycin-Susceptible and Heterogeneous Staphylococcus aureus Isolates: Comparison of Etest and Agar Screening Methods

RIEDERER, K. M., Shemes, S. P., Chase, P., Musta, A. C., mar, A. É., & Khatib, R. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.01435-10 · Cited by 57 · see citing works

Heteroresistance to carbapenems in Acinetobacter baumannii

Pournaras, S., Ikonomidis, A., Markogiannakis, A., et al. (2005) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dki115 · Cited by 57 · see citing works

Evaluation of heteroresistance to polymyxin B among carbapenem-susceptible and -resistant Pseudomonas aeruginosa

Hermes, D. M., Pitt, C. P., Lutz, L., Teixeira, A. B., Ribeiro, V. B., Netto, B., Martins, A. F., Zavascki, A. P., & Barth, A. L. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.059220-0 · Cited by 57 · see citing works

Heterogeneity in susceptibility to metronidazole among Helicobacter pylori isolates from patients with gastritis or peptic ulcer disease

Weel, J. F. L., van der Hulst, R. W., Gerrits, Y., et al. (1996) · Journal of Clinical Microbiology · doi:10.1128/jcm.34.9.2158-2162.1996 · Cited by 57 · see citing works

Comparison of the clinical features, bacterial genotypes and outcomes of patients with bacteraemia due to heteroresistant vancomycin-intermediate Staphylococcus aureus and vancomycin-susceptible S. aureus

Park, K.-H., Kim, E. S., Kim, H.-S., Park, S. J., Bang, K. M., Park, H. J., Park, S.-Y., Moon, S. M., Chong, Y. P., Kim, S., et al. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks131 · Cited by 56 · see citing works

Imipenem heteroresistance induced by imipenem in multidrug-resistant Acinetobacter baumannii: mechanism and clinical implications

Lee, H.-Y., Chen, C., Wang, S.-B., et al. (2011) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2010.12.015 · Cited by 56 · see citing works

Detection of Staphylococcus aureus Isolates with Heterogeneous Intermediate-Level Resistance to Vancomycin in the United States

Richter, S. S., Satola, S. W., Crispell, E. K., Heilmann, K. P., Dohrn, C. L., Riahi, F., Costello, A. J., Diekema, D. J., & Doern, G. V. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.01152-11 · Cited by 55 · see citing works

Genetic control of population structure in heterogeneous strains of methicillin resistantStaphylococcus aureus

de LENCASTRE, H., Figueiredo, A. M. S., & Tomasz, A. (1993) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/bf02389872 · Cited by 54 · see citing works

Heteroresistance of Helicobacter pylori from the same patient prior to antibiotic treatment

Kao, C., Lee, A.-Y., Huang, A.-H., Song, P.-Y., Yang, Y., Sheu, S., Chang, W.-L., Sheu, B., & Wu, J.-J. (2014) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2014.02.009 · Cited by 53 · see citing works

Unstable Vancomycin Heteroresistance Is Common among Clinical Isolates of Methiciliin-Resistant Staphylococcus aureus

Plipat, N., Livni, G., Bertram, H. C., & Thomson, R. B. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.5.2494-2496.2005 · Cited by 52 · see citing works

Impact ofsarandagron methicillin resistance inStaphylococcus aureus

Durán, S. P., Kayser, F. H., & Berger‐Bächi, B. (1996) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1996.tb08394.x · Cited by 52 · see citing works

Antimicrobial Resistance in Coagulase-Negative Staphylococci

Hamilton-Miller, J. M. T., & Iliffe, A. (1985) · Journal of Medical Microbiology · doi:10.1099/00222615-19-2-217 · Cited by 52 · see citing works

MODE OF ACTION OF STREPTOMYCIN ON TYPE b HEMOPHILUS INFLUENZAE

Alexander, H. E., & Leidy, G. (1947) · Journal of Experimental Medicine · doi:10.1084/jem.85.6.607 · Cited by 51 · see citing works

Characterization of clinical isolates of Pseudomonas aeruginosa heterogeneously resistant to carbapenems

Pournaras, S., Ikonomidis, A., Markogiannakis, A., Spanakis, N., Maniatis, A. N., & Tsakris, A. (2006) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46816-0 · Cited by 51 · see citing works

Detection and Characterization of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Isolates in Canada: Results from the Canadian Nosocomial Infection Surveillance Program, 1995-2006

Adam, H. J., Louie, L., Watt, C., et al. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01316-09 · Cited by 51 · see citing works

Etest synergy testing of clinical isolates of Staphylococcus aureus demonstrating heterogeneous resistance to vancomycin

Tsuji, B. T., & Rybak, M. J. (2005) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2005.08.014 · Cited by 49 · see citing works

Glutamine Synthetase and Heteroresistance in Methicillin-Resistant Staphylococcus aureus

Stranden, A., Roos, M. A., & Berger‐Bächi, B. (1996) · Microbial Drug Resistance · doi:10.1089/mdr.1996.2.201 · Cited by 48 · see citing works

Changing Italian nosocomial-community trends and heteroresistance in Staphylococcus aureus from bacteremia and endocarditis

Campanile, F., Bongiorno, D., Falcone, M., Vailati, F., Pasticci, M. B., Perez, M. P., Raglio, A., Rumpianesi, F., Scuderi, C., Suter, F., et al. (2011) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-011-1367-y · Cited by 48 · see citing works

Polyamines Can Increase Resistance of Neisseria gonorrhoeae to Mediators of the Innate Human Host Defense

Goytia, M., & Shafer, W. M. (2010) · Infection and Immunity · doi:10.1128/iai.01301-09 · Cited by 48 · see citing works

Molecular nature of two Haemophilus influenzae R factors containing resistances and the multiple integration of drug resistance transposons

Jahn, G., Laufs, R., Kaulfers, P.-M., et al. (1979) · Journal of Bacteriology · doi:10.1128/jb.138.2.584-597.1979 · Cited by 47 · see citing works

Expression and detection of hetero-vancomycin resistance in Staphylococcus aureus

Howe, R. A., Wootton, M., Walsh, T. R., Bennett, P. M., & MacGowan, A. P. (1999) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/44.5.675 · Cited by 46 · see citing works

Development of homogeneous expression of resistance in methicillin-resistant Staphylococcus aureus clinical strains is functionally associated with a β-lactam-mediated SOS response

Cuirolo, A., Plata, K. B., & Rosato, A. E. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp164 · Cited by 45 · see citing works

Vancomycin Heteroresistance in Bloodstream Isolates of Staphylococcus capitis

D'mello, D., Daley, A. J., Rahman, M. S., et al. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.00592-08 · Cited by 45 · see citing works

Bordetella pertussis Isolates with a Heterogeneous Phenotype for Erythromycin Resistance

Wilson, K. E., Cassiday, P. K., Popovic, T., et al. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.8.2942-2944.2002 · Cited by 43 · see citing works

Prevalence, Molecular Epidemiology, and Clinical Significance of Heterogeneous Glycopeptide-Intermediate Staphylococcus aureus in Liver Transplant Recipients

Bert, F., Clarissou, J., Durand, F., Delefosse, D., Chauvet, C., Lefebvre, P., Lambert, N., & Branger, C. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.11.5147-5152.2003 · Cited by 42 · see citing works

Vancomycin Susceptibility Trends and Prevalence of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus in Clinical Methicillin-Resistant S. aureus Isolates

Pitz, A. M., Yu, F., Hermsen, E. D., Rupp, M. E., Fey, P. D., & Olsen, K. M. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.00914-10 · Cited by 42 · see citing works

Heteroresistance to Cephalosporins and Penicillins in Acinetobacter baumannii

Hung, K., Wang, M.-C., Huang, A.-H., et al. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.05085-11 · Cited by 41 · see citing works

Heteroresistance to Vancomycin in Enterococcus faecium

Alam, M. R., Donabedian, S. M., Brown, W. J., et al. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.9.3379-3381.2001 · Cited by 40 · see citing works

Heteroresistance to Fosfomycin Is Predominant in Streptococcus pneumoniae and Depends on the murA1 Gene

Engel, H., Gutiérrez‐Fernández, J., Flückiger, C., et al. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00223-13 · Cited by 39 · see citing works

Heteroresistance to glycopeptides in Italian meticillin-resistant Staphylococcus aureus (MRSA) isolates

Campanile, F., Borbone, S., Perez, M., Bongiorno, D., Cafiso, V., Bertuccio, T., Purrello, S., Nicolosi, D., Scuderi, C., & Stefani, S. (2010) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2010.06.044 · Cited by 39 · see citing works

Efflux system overexpression and decreased OprD contribute to the carbapenem heterogeneity inPseudomonas aeruginosa

Ikonomidis, A., Tsakris, A., Καντζάνου, Μ., et al. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.00997.x · Cited by 38 · see citing works

Heteroresistance to Meropenem in Carbapenem-Susceptible Acinetobacter baumannii

Ikonomidis, A., Neou, E., Gogou, V. A., et al. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.00959-09 · Cited by 38 · see citing works

First Characterization of Heterogeneous Resistance to Imipenem in Invasive Nontypeable Haemophilus influenzae Isolates

Cerquetti, M., Giufrè, M., Cardines, R., et al. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00335-07 · Cited by 37 · see citing works

Molecular epidemiology and clinical characteristics of hetero-resistant vancomycin intermediate Staphylococcus aureus bacteremia in a Taiwan Medical Center

Lin, S., Chen, T., Chen, F.-J., et al. (2012) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2012.05.004 · Cited by 37 · see citing works

Methicillin resistance and vancomycin heteroresistance in Staphylococcus aureus in cystic fibrosis patients

Cafiso, V., Bertuccio, T., Spina, D., Campanile, F., Bongiorno, D., Santagati, M., Sciacca, A., Sciuto, C., & Stefani, S. (2010) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-010-1000-5 · Cited by 36 · see citing works

VanB Phenotype- vanA Genotype Enterococcus faecium with Heterogeneous Expression of Teicoplanin Resistance

Park, I. J., Lee, W. G., Shin, J. H., et al. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.00712-08 · Cited by 36 · see citing works

Heterogeneously vancomycin-intermediate Staphylococcus aureus (hVISA) emerged before the clinical introduction of vancomycin in Japan: a retrospective study

Yamakawa, J., Kurosawa, H., Kaneko, K., Yamakawa, J., AMINAKA, M., Hori, S., Cui, L., Ito, T., Jin, J., Hiramatsu, K., et al. (2011) · Journal of Infection and Chemotherapy · doi:10.1007/s10156-011-0330-2 · Cited by 35 · see citing works

Heterogeneous resistance to vancomycin and teicoplanin among Staphylococcus spp. isolated from bacteremia

Nunes, A. P. F., Schuenck, R. P., Bastos, C. C. R., et al. (2007) · The Brazilian Journal of Infectious Diseases · doi:10.1590/s1413-86702007000300009 · Cited by 35 · see citing works

Heterogeneity of susceptibility to fluoroquinolones in Bartonella isolates from Australia reveals a natural mutation in gyrA

Angelakis, E., Biswas, S., Taylor, C. T., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn094 · Cited by 35 · see citing works

Vancomycin heteroresistance and biofilm formation in Staphylococcus epidermidis from food

Gazzola, S., & Cocconcelli, P. S. (2008) · Microbiology · doi:10.1099/mic.0.2008/021154-0 · Cited by 35 · see citing works

A multi-center blinded study on the efficiency of phenotypic screening methods to detect glycopeptide intermediately susceptible Staphylococcus aureus (GISA) and heterogeneous GISA (h-GISA)

Voß, A., Mouton, J. W., van Elzakker, E. P., Hendrix, R., Goessens, W. H. F., Kluytmans, J. A. J. W., Krabbe, P. F. M., de Neeling, A. J., Sloos, J. H., Öztoprak, N., et al. (2007) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/1476-0711-6-9 · Cited by 34 · see citing works

Targeting of PBP1 by β-lactams Determines recA/SOS Response Activation in Heterogeneous MRSA Clinical Strains

Plata, K. B., Riosa, S., Singh, C. R., Rosato, R. R., & Rosato, A. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061083 · Cited by 33 · see citing works

Physiological and molecular analysis of a mecA-negative Staphylococcus aureus clinical strain that expresses heterogeneous methicillin resistance

Yoshida, R. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg036 · Cited by 32 · see citing works

Characterization of heterogeneous vancomycin-intermediate resistance, MIC and accessory gene regulator (agr) dysfunction among clinical bloodstream isolates of staphyloccocus aureus

Harigaya, Y., Ngo, D., Lesse, A. J., et al. (2011) · BMC Infectious Diseases · doi:10.1186/1471-2334-11-287 · Cited by 32 · see citing works

Effect of exogenous glycine on peptidoglycan composition and resistance in a methicillin-resistant Staphylococcus aureus strain

DeJonge, B. L. M., Chang, Y. S., Xu, N., et al. (1996) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.40.6.1498 · Cited by 31 · see citing works

Activity of telavancin against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) in vitro and in an in vivo mouse model of bacteraemia

Hegde, S. S., Skinner, R., Lewis, S. R., et al. (2010) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkq028 · Cited by 31 · see citing works

A Low-Affinity Penicillin-Binding Protein 2x Variant Is Required for Heteroresistance in Streptococcus pneumoniae

Engel, H., Mika, M., Denapaite, D., Hakenbeck, R., Mühlemann, K., Heller, M., Hathaway, L. J., & Hilty, M. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02547-14 · Cited by 30 · see citing works

Ceftaroline-Heteroresistant Staphylococcus aureus

Saravolatz, S. N., Martin, H., Pawlak, J., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02685-13 · Cited by 27 · see citing works

Vancomycin and daptomycin minimum inhibitory concentration distribution and occurrence of heteroresistance among methicillin-resistant Staphylococcus aureus blood isolates in Turkey

Sancak, B., Yağcı, S., Gür, D., Gülay, Z., Öğünç, D., Söyletir, G., Yalçın, A. N., Dündar, D., Topçu, A. W., Akşit, F., et al. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-583 · Cited by 26 · see citing works

Lower autolytic activity in a homogeneous methicillin-resistant Staphylococcus aureus strain compared to derived heterogeneous-resistant and susceptible strains

Gustafson, J. E., & Wilkinson, B. J. (1989) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1989.tb03092.x · Cited by 26 · see citing works

Pharmacodynamic effect of clinical vancomycin exposures on cell wall thickness in heterogeneous vancomycin-intermediate Staphylococcus aureus

Rose, W. E., Knier, R., & Hutson, P. R. (2010) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkq292 · Cited by 26 · see citing works

In vivo development of heterogeneous glycopeptide-intermediate Staphylococcus aureus (hGISA), GISA and daptomycin resistance in a patient with meticillin-resistant S. aureus endocarditis

Kirby, A., Mohandas, K., Broughton, C. M., et al. (2009) · Journal of Medical Microbiology · doi:10.1099/jmm.0.006486-0 · Cited by 26 · see citing works

Acquired and Native Resistance of Staphylococcus aureus to Cephalexin and Other β-Lactam Antibiotics

Kayser, F. H., Benner, E. J., & Hoeprich, P. D. (1970) · Applied Microbiology · doi:10.1128/am.20.1.1-5.1970 · Cited by 25 · see citing works

Investigation of Staphylococcus strains with heterogeneous resistance to glycopeptides in a Turkish university hospital

Naki̇poğlu, Y., Derbentli, Ş., Çağatay, A., et al. (2005) · BMC Infectious Diseases · doi:10.1186/1471-2334-5-31 · Cited by 25 · see citing works

Editorial Response: Relapsing Infection Due to Enterobacter Species: Lessons of Heterogeneity

Medeiros, A. A. (1997) · Clinical Infectious Diseases · doi:10.1086/516918 · Cited by 24 · see citing works

Transcriptional responses of Burkholderia cenocepacia to polymyxin B in isogenic strains with diverse polymyxin B resistance phenotypes

Loutet, S. A., Lorenzo, F. D., Clarke, C., et al. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-472 · Cited by 24 · see citing works

Heterogeneous vancomycin-intermediate susceptibility in a community-associated methicillin-resistant Staphylococcus aureus epidemic clone, in a case of Infective Endocarditis in Argentina

Sola, C., Lamberghini, R. O., Ciarlantini, M., Egea, A. L., González, P., Diaz, E. G., Huerta, V., Gonzalez, J., Corso, A. C., Vilaró, M., et al. (2011) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/1476-0711-10-15 · Cited by 24 · see citing works

Acquisition of Colistin Resistance Links Cell Membrane Thickness Alteration with a Point Mutation in the lpxD Gene in Acinetobacter baumannii

Saleh, N. M., Hesham, M. S., Amin, M. A., et al. (2020) · Antibiotics · doi:10.3390/antibiotics9040164 · Cited by 24 · see citing works

Epidemiological and clinical features associated with colonisation/infection by Acinetobacter baumannii with phenotypic heterogeneous resistance to carbapenems

Fernández-Cuenca, F., Gómez-Sánchez, M. C., Rodríguez‐Baño, J., et al. (2012) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2012.05.005 · Cited by 23 · see citing works

Heteroresistance to vancomycin and novel point mutations in Tn1546 of Enterococcus faecium ATCC 51559

Khan, S. A., Sung, K., Layton, S. L., & Nawaz, M. S. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.08.007 · Cited by 23 · see citing works

Accurate assessment of antibiotic susceptibility and screening resistant strains of a bacterial population by linear gradient plate

Liu, Y., Li, J., Du, J.-F., et al. (2011) · Science China Life Sciences · doi:10.1007/s11427-011-4230-6 · Cited by 22 · see citing works

No Evidence of Vancomycin Minimal Inhibitory Concentration Creep or Heteroresistance Identified in Pediatric Staphylococcus aureus Blood Isolates

Goldman, J. L., Harrison, C. J., Myers, A., Jackson, M. A., & Selvarangan, R. (2014) · The Pediatric Infectious Disease Journal · doi:10.1097/01.inf.0000436281.18687.0c · Cited by 22 · see citing works

β-Lactam coselection of sensitive and TEM-1 β-lactamase-producing subpopulations in heterogeneous Escherichia coli colonies

Baqnero, F., Vicente, M. F., & Pérez-Díaz, J. C. (1985) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/15.2.151 · Cited by 22 · see citing works

Clinical failure of vancomycin in a dialysis patient with methicillin-susceptible vancomycin-heteroresistant S. aureus

Fusco, D. N., Alexander, E. L., Weisenberg, S. A., Mediavilla, J. R., Kreiswirth, B. N., Schuetz, A. N., Jenkins, S. G., & Rhee, K. Y. (2009) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.05.017 · Cited by 21 · see citing works

mecA Is Not Involved in the σ B -Dependent Switch of the Expression Phenotype of Methicillin Resistance in Staphylococcus epidermidis

Knobloch, J. K. ‐., Jäger, S., Huck, J., et al. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.3.1216-1219.2005 · Cited by 21 · see citing works

Clinical isolates of Staphylococcus aureus from 1987 and 1989 demonstrating heterogeneous resistance to vancomycin and teicoplanin

Rybak, M. J., Cha, R., Cheung, C. M., Meka, V. G., & Kaatz, G. W. (2005) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2004.09.005 · Cited by 21 · see citing works

Identification of Cephalosporin-Resistant Staphylococcus aureus with the Disc Diffusion Method

Hallander, H. O., & Laurell, G. (1972) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.1.5.422 · Cited by 21 · see citing works

The incidence of heterogeneous vancomycin-intermediate Staphylococcus aureus correlated with increase of vancomycin MIC

Chen, H., Liu, Y., Sun, W., et al. (2011) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2011.06.010 · Cited by 21 · see citing works

Ribulose bisphosphate carboxylase of the procaryotic symbiont of a hydrothermal vent tube worm: kinetics, activity and gene hybridization

Williams, C. A., Nelson, D. C., Farah, B. A., et al. (1988) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1988.tb02920.x · Cited by 20 · see citing works

Lack of Correlation Between β-Lactamase Production and Susceptibility to Cefamandole or Cefoxitin Among Spontaneous Mutants of Enterobacteriaceae

OTT, J. L., Turner, J. R., & Mahoney, D. F. (1979) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.15.1.14 · Cited by 19 · see citing works

Indications of carbapenem resistance evolution through heteroresistance as an intermediate stage in Acinetobacter baumannii after carbapenem administration

Superti, S. V., Martins, D. D. S., Caierão, J., et al. (2009) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46652009000200010 · Cited by 18 · see citing works

Recurrence of heterogeneous methicillin-resistant Staphylococcus aureus (MRSA) among the MRSA clinical isolates in a Japanese university hospital

Kishii, K., Ito, T., Watanabe, S., et al. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn186 · Cited by 18 · see citing works

Heterogeneous expression of glycopeptide resistance in enterococci associated with transfer of vanB

Hayden, M. K., Picken, R. N., & Sahm, D. F. (1997) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.41.4.872 · Cited by 18 · see citing works

Heterogeneity of Methicillin-Resistant Staphylococcus aureus Strains (MRSA) Characterized by Flow Cytometry

Jarzembowski, T., Wiśniewska, K., Jóźwik, A., et al. (2009) · Current Microbiology · doi:10.1007/s00284-009-9395-x · Cited by 16 · see citing works

Heterogeneous expression of fusidic acid resistance in Staphylococcus aureus with plasmid or chromosomally encoded fusidic acid resistance genes

O’Brien, F. G., Botterill, C. I., Endersby, T. S. G., et al. (1998) · Pathology · doi:10.1080/00313029800169486 · Cited by 16 · see citing works

Fate of Mutation Rate Depends on agr Locus Expression during Oxacillin-Mediated Heterogeneous-Homogeneous Selection in Methicillin-Resistant Staphylococcus aureus Clinical Strains

Plata, K. B., Rosato, R. R., & Rosato, A. E. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01119-09 · Cited by 16 · see citing works

Failure of the MicroScan WalkAway System To Detect Heteroresistance to Carbapenems in a Patient with Enterobacter aerogenes Bacteremia

Gordon, N. C., & Wareham, D. W. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.01033-09 · Cited by 15 · see citing works

Modified PAP method to detect heteroresistance to vancomycin among methicillin resistant Staphylococcus aureus isolates at a tertiary care hospital

Iyer, R., & Hittinahalli, V. (2008) · Indian Journal of Medical Microbiology · doi:10.4103/0255-0857.40537 · Cited by 11 · see citing works

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistantStaphylococcus aureus from a Greek hospital

Tassios, P. T., Vatopoulos, A. C., Xanthaki, A., et al. (1997) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/bf01709481 · Cited by 10 · see citing works

Heteroresistance to Carbapenems in New Delhi Metallo-β-Lactamase-1–Producing Isolates: A Challenge for Detection?

Zavascki, A. P., Falci, D. R., da Silva, R. C. F., et al. (2014) · Infection Control and Hospital Epidemiology · doi:10.1086/676442 · Cited by 10 · see citing works

Misidentification of ampicillin–sulbactam heteroresistance in Acinetobacter baumannii strains from ICU patients

Savini, V., Catavitello, C., Talia, M., et al. (2009) · Journal of Infection · doi:10.1016/j.jinf.2009.02.001 · Cited by 10 · see citing works

Challenges in the microbiological diagnosis and management of hVISA infections

Cheong, J. W. S., Harris, P. N. A., Oman, K. M., & Norton, R. E. (2011) · Pathology · doi:10.1097/pat.0b013e3283464ca3 · Cited by 9 · see citing works

POPULATION ANALYSIS OF SUSCEPTIBILITY TO CIPROFLOXACIN AND NALIDIXIC ACID IN STAPHYLOCOCCUS, PSEUDOMONAS AERUGINOSA, AND ENTEROBACTERIACEAE

Søgaard, P., & Gahrn‐Hansen, B. (1986) · Acta Pathologica Microbiologica Scandinavica Section B Microbiology · doi:10.1111/j.1699-0463.1986.tb03066.x · Cited by 8 · see citing works

Population Analysis of Susceptibility To Cefotaxime in Enterobacteriaceae

Søgaard, P. (1985) · Acta Pathologica Microbiologica Scandinavica Section B Microbiology · doi:10.1111/j.1699-0463.1985.tb02902.x · Cited by 8 · see citing works

Cell wall deficiency and its effect on methicillin heteroresistance in Staphylococcus aureus

Markova, N., Haydoushka, I., Michailova, L., et al. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.09.015 · Cited by 7 · see citing works

The presence of heterogeneous vancomycin-lntermediate Staphylococcus aureus (heteroVISA) in a major Malaysian hospital.

Norazah, A., Law, N. L., Kamel, A. G. M., et al. (2012) · PubMed · Cited by 7 · see citing works

Low Prevalence of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Isolates among Connecticut Veterans

Fink, S. L., Martinello, R. A., Campbell, S. M., & Murray, T. S. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05024-11 · Cited by 6 · see citing works

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

Brauner, A., Fridman, O., Gefen, O., & Balaban, N. Q. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.34 · Cited by 1,612 · see citing works

Definitions and guidelines for research on antibiotic persistence

Balaban, N. Q., Helaine, S., Lewis, K., Ackermann, M., Aldridge, B., Andersson, D. I., Brynildsen, M. P., Bumann, D., Camilli, A., Collins, J. J., et al. (2019) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0196-3 · Cited by 1,313 · see citing works

Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis

Stone, N. R. H., Rhodes, J., Fisher, M. C., Mfinanga, S., Kivuyo, S., Rugemalila, J., Segal, E. S., Needleman, L., Molloy, S. F., Kwon-Chung, J., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci124516 · Cited by 167 · see citing works

Treatment of Invasive Candidiasis: A Narrative Review

Ben-Ami, R. (2018) · Journal of Fungi · doi:10.3390/jof4030097 · Cited by 111 · see citing works

Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with <i>In Vivo</i> Persistence

Ben-Ami, R., Zimmerman, O., Finn, T., Amit, S., Novikov, A., Wertheimer, N., Lurie-Weinberger, M., & Berman, J. (2016) · mBio · doi:10.1128/mbio.00655-16 · Cited by 88 · see citing works

Azole Resistance in Candida glabrata

Whaley, S. G., & Rogers, P. D. (2016) · Current Infectious Disease Reports · doi:10.1007/s11908-016-0554-5 · Cited by 85 · see citing works

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications

Rogers, T. R., Verweij, P. E., Castanheira, M., Dannaoui, E., White, P. L., Arendrup, M. C., Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST), Arendrup, M. C., Arikan-Akdagli, S., Barchiesi, F., et al. (2022) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkac161 · Cited by 82 · see citing works

Combined effect of Polymyxin B and Tigecycline to overcome Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae

Tian, Y., Zhang, Q., Wen, L., & Chen, J. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.00152-21 · Cited by 62 · see citing works

Antifungal heteroresistance causes prophylaxis failure and facilitates breakthrough Candida parapsilosis infections

Zhai, B., Liao, C., Jaggavarapu, S., Tang, Y., Rolling, T., Ning, Y., Sun, T., Bergin, S. A., Gjonbalaj, M., Miranda, E., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03183-4 · Cited by 62 · see citing works

Impact of tolerance to fluconazole on treatment response in <i>Candida albicans</i> bloodstream infection

Levinson, T., Dahan, A., Novikov, A., Paran, Y., Berman, J., & Ben‐Ami, R. (2021) · Mycoses · doi:10.1111/myc.13191 · Cited by 50 · see citing works

Plasmonic Colloidosome-Coupled MALDI-TOF MS for Bacterial Heteroresistance Study at Single-Cell Level

Dai, Y., Li, C., Yi, J., Qin, Q., Liu, B., & Qiao, L. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c00494 · Cited by 31 · see citing works

Heteroresistance Is Associated With in vitro Regrowth During Colistin Treatment in Carbapenem-Resistant Klebsiella pneumoniae

Wang, Y., Ma, X., Zhao, L., He, Y., Yu, W., Fu, S., Ni, W., & Gao, Z. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.868991 · Cited by 27 · see citing works

Approaches for identifying and measuring heteroresistance in azole-susceptible <i>Candida</i> isolates

Gautier, C., Maciel, E. I., & Ene, I. V. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.04041-23 · Cited by 23 · see citing works

Investigation of fluconazole heteroresistance in clinical and environmental isolates of <i>Cryptococcus neoformans</i> complex and <i>Cryptococcus gattii</i> complex in the state of Amazonas, Brazil

Moreira, I. D. M. B., Cortez, A. C. A., de Souza, É. S., Pinheiro, S. B., de Souza Oliveira, J. G., Sadahiro, A., Cruz, K. S., Matsuura, A. B. J., Melhem, M. D. S. C., Frickmann, H., et al. (2022) · Medical Mycology · doi:10.1093/mmy/myac005 · Cited by 22 · see citing works

Impact of Carbapenem Heteroresistance Among Multidrug-Resistant ESBL/AmpC-Producing Klebsiella pneumoniae Clinical Isolates on Antibiotic Treatment in Experimentally Infected Mice

Xiong, Y., Han, Y., Zhao, Z., Gao, W., Ma, Y., Jiang, S., Wang, M., Zhang, Q., Zhou, Y., & Chen, Y. (2021) · Infection and Drug Resistance · doi:10.2147/idr.s340652 · Cited by 22 · see citing works

Carbapenem-resistant K. pneumoniae exhibiting clinically undetected amikacin and meropenem heteroresistance leads to treatment failure in a murine model of infection

Zhang, F., Ding, M., Yan, X., Bai, J., Li, Q., Zhang, B., Liang, Q., Liang, S., Wang, G., & Zhou, Y. (2021) · Microbial Pathogenesis · doi:10.1016/j.micpath.2021.105162 · Cited by 17 · see citing works

Insight into the Mechanisms and Clinical Relevance of Antifungal Heteroresistance

Su, Y., Li, Y., Yi, Q., Xu, Y., Sun, T., & Li, Y. (2025) · Journal of Fungi · doi:10.3390/jof11020143 · Cited by 18 · see citing works

Epidemiology of cryptococcal meningitis and fluconazole heteroresistance in <i>Cryptococcus neoformans</i> isolates from a teaching hospital in southwestern China

Huang, Y., Zhang, Y., Yang, S., Lu, H., Yu, H., Wang, X., Jia, X., Tang, D., Wu, L., Huang, S., et al. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.00725-24 · Cited by 12 · see citing works

Phenotypic Detection of Hemin-Inducible Trimethoprim-Sulfamethoxazole Heteroresistance in Staphylococcus aureus

Nurjadi, D., Chanthalangsy, Q., Zizmann, E., Stuermer, V., Moll, M., Klein, S., Boutin, S., Heeg, K., & Zanger, P. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.01510-21 · Cited by 10 · see citing works

Classroom understanding: An expanded notion of teacher clarity

Simonds, C. J. (1997) · Communication Research Reports · doi:10.1080/08824099709388671 · Cited by 64 · see citing works

Review of: "The Success of Ecological Leadership for the Church Expectations"

Mukhlisin, A. (2023) · doi:10.32388/x0u10h

Effect of Teacher Clarity on Student Achievement in Science.

Smith, L. R. (1980) · Cited by 1 · see citing works

Actual and perceived teacher clarity ‐ relations to student achievement in science

Land, M. L. (1981) · Journal of Research in Science Teaching · doi:10.1002/tea.3660180206 · Cited by 18 · see citing works

Lead your ACE: Accuracy, clarity, and effectiveness in technical writing

Corey, J. (1983) · IEEE Transactions on Professional Communication · doi:10.1109/tpc.1983.6448654 · Cited by 1 · see citing works