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Cited by 271

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase

Open access
Morrison, A, Christensen, R B, Alley, J, Beck, A K, Bernstine, E G, Lemontt, J F, Lawrence, C W·1989·Journal of Bacteriology

Abstract

We have cloned the REV3 gene of Saccharomyces cerevisiae by complementation of the rev3 defect in UV-induced mutagenesis. The nucleotide sequence of this gene encodes a predicted protein of Mr 172,956 showing significant sequence similarity to Epstein-Barr virus DNA polymerase and to other members of a class of DNA polymerases including human DNA polymerase alpha and yeast DNA polymerase I. REV3 protein shows less sequence identity, and presumably a more distant evolutionary relationship, to the latter two enzymes than they do to each other. Haploids carrying a complete deletion of REV3 are viable. We suggest that induced mutagenesis in S. cerevisiae depends on a specialized DNA polymerase that is not required for other replicative processes. REV3 is located 2.8 centimorgans from CDC60, on chromosome XVI.

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Crossref · 10.1128/jb.171.10.5659-5667.1989

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Metadata

Authors
Morrison, A., Christensen, R. B., Alley, J., Beck, A. K., Bernstine, E. G., Lemontt, J. F., & Lawrence, C. W.
Venue
Journal of Bacteriology
Published
1989-10
Volume
171
Issue
10
Pages
5659-5667
ISSN
  • 0021-9193 (ISSN-L)
  • 1098-5530
OpenAlex
W1900509644
Cited by
271
References
33
FWCI
4.71
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. https://app.cochat.ai/papers/10.1128/jb.171.10.5659-5667.1989
The paper
Morrison, A., Christensen, R. B., Alley, J., Beck, A. K., Bernstine, E. G., Lemontt, J. F., & Lawrence, C. W. (1989). REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. Journal of Bacteriology. https://doi.org/10.1128/jb.171.10.5659-5667.1989

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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