Glycerol monolaurate inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961 · see citing works

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,311 · see citing works

A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots

Blake, M. S., Johnston, K. H., Russell-Jones, G. J., & Gotschlich, E. C. (1984) · Analytical Biochemistry · doi:10.1016/0003-2697(84)90320-8 · Cited by 2,136 · see citing works

Novel Method for Detection of β-Lactamases by Using a Chromogenic Cephalosporin Substrate

O'Callaghan, C. H., Morris, A., Kirby, S. M., & Shingler, A. H. (1972) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.1.4.283 · Cited by 1,837 · see citing works

Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule.

Novick, R. P., Ross, H. F., Projan, S. J., Kornblum, J. S., Kreiswirth, B. N., & Moghazeh, S. L. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06074.x · Cited by 1,071 · see citing works

Regulation of exoprotein gene expression in Staphylococcus aureus by agr

Recsei, P. A., Kreiswirth, B. N., O’Reilly, M., Schlievert, P. M., Gruss, A., & Novick, R. P. (1986) · Molecular and General Genetics MGG · doi:10.1007/bf00330517 · Cited by 619 · see citing works

The role of the delta‐lysin gene (hld) in the regulation of virulence genes by the accessory gene regulator (agr) in Staphylococcus aureus.

Janzon, L., & Arvidson, S. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb08254.x · Cited by 298 · see citing works

Penicillinase plasmids of Staphylococcus aureus: Restriction-deletion maps

Novick, R. P., Murphy, E., Gryczan, T. J., Baron, E. S., & Edelman, I. (1979) · Plasmid · doi:10.1016/0147-619x(79)90010-6 · Cited by 234 · see citing works

Nature and Interactions of the Genetic Elements Governing Penicillinase Synthesis in Staphylococcus aureus

Novick, R. P., & Richmond, M. H. (1965) · Journal of Bacteriology · doi:10.1128/jb.90.2.467-480.1965 · Cited by 228 · see citing works

Production of Staphylococcal Pyrogenic Exotoxin Type C: Influence of Physical and Chemical Factors

Schlievert, P. M., & Blomster, D. A. (1983) · The Journal of Infectious Diseases · doi:10.1093/infdis/147.2.236 · Cited by 204 · see citing works

A temporal signal, independent of agr, is required for hla but not spa transcription in Staphylococcus aureus

Vandenesch, F., Kornblum, J. S., & Novick, R. P. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.20.6313-6320.1991 · Cited by 183 · see citing works

Glucose and nonmaintained pH decrease expression of the accessory gene regulator (agr) in Staphylococcus aureus

Regassa, L. B., Novick, R. P., & Betley, M. J. (1992) · Infection and Immunity · doi:10.1128/iai.60.8.3381-3388.1992 · Cited by 181 · see citing works

Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46

Gray, G. S., & Kehoe, M. (1984) · Infection and Immunity · doi:10.1128/iai.46.2.615-618.1984 · Cited by 168 · see citing works

Cloning of a chromosomal locus (exp) which regulates the expression of several exoprotein genes in Staphylococcus aureus

Morfeldt, E., Janzou, L., Arvidson, S., & Löfdahl, S. (1988) · Molecular and General Genetics MGG · doi:10.1007/bf00425697 · Cited by 163 · see citing works

Staphylococcus aureus Bacteriophages Mediating the Simultaneous Lysogenic Conversion of -Lysin, Staphylokinase and Enterotoxin A: Molecular Mechanism of Triple Conversion

Coleman, D. C., Sullivan, D. J., Russell, R. J., Arbuthnott, J. P., Carey, B., & Pomeroy, H. (1989) · Microbiology · doi:10.1099/00221287-135-6-1679 · Cited by 158 · see citing works

Effect of glycerol monolaurate on bacterial growth and toxin production

Schlievert, P. M., Deringer, J. R., Kim, M. H., Projan, S. J., & Novick, R. P. (1992) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.36.3.626 · Cited by 127 · see citing works

[30] Assay of hemolytic toxins

Bernheimer, A. W. (1988) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(88)65033-6 · Cited by 111 · see citing works

Steady-state staphylococcal enterotoxin type C mRNA is affected by a product of the accessory gene regulator (agr) and by glucose

Regassa, L. B., Couch, J. L., & Betley, M. J. (1991) · Infection and Immunity · doi:10.1128/iai.59.3.955-962.1991 · Cited by 97 · see citing works

A rapid method to quantitate non-labeled RNA species in bacterial cells

Kornblum, J. S., Projan, S. J., Moghazeh, S. L., & Novick, R. P. (1988) · Gene · doi:10.1016/0378-1119(88)90547-1 · Cited by 72 · see citing works

THE DISEASE SPECTRUM, EPIDEMIOLOGY, AND ETIOLOGY OF TOXIC-SHOCK SYNDROME

Chesney, P. J., Bergdoll, M. S., Davis, J. P., & Vergeront, J. M. (1984) · Annual Review of Microbiology · doi:10.1146/annurev.mi.38.100184.001531 · Cited by 66 · see citing works

Regulation of the protein A-encoding gene in Staphylococcus aureus

Patel, A. H., Kornblum, J. S., Kreiswirth, B. N., Novick, R. P., & Foster, T. J. (1992) · Gene · doi:10.1016/0378-1119(92)90703-r · Cited by 46 · see citing works

Environmental factors affecting toxic shock syndrome toxin-1 (TSST-1) synthesis

Sarafian, S. K., & Morse, S. A. (1987) · Journal of Medical Microbiology · doi:10.1099/00222615-24-1-75 · Cited by 35 · see citing works

Translational fusion with a secretory enzyme as an indicator

Wang, P.-Z., Projan, S. J., Leason, K. R., & Novick, R. P. (1987) · Journal of Bacteriology · doi:10.1128/jb.169.7.3082-3087.1987 · Cited by 34 · see citing works

Nucleotide sequence of β-lactamase regulatory genes from staphylococcal plasmid p1258

Wang, P.-Z., Projan, S. J., & Novick, R. P. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.14.4000 · Cited by 32 · see citing works

Toxic-shock syndrome: A commentary and review of the characteristics of Staphylococcus aureus strains

Chesney, P. J. (1983) · Infection · doi:10.1007/bf01641192 · Cited by 20 · see citing works

Cloning and expression of streptococcal pyrogenic exotoxin A and staphylococcal toxic shock syndrome toxin-1 in Bacillus subtilis

Kreiswirth, B. N., Handley, J., Schlievert, P. M., & Novick, R. P. (1987) · Molecular and General Genetics MGG · doi:10.1007/bf00330426 · Cited by 19 · see citing works

Interaction of BlaI, the repressor for the β‐lactamase gene of Bacillus licheniformis, with the blaP and blaI promoters

Grossman, M. J., Curran, I. H. A., & Lampen, J. O. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)80258-3 · Cited by 6 · see citing works

Staphylococcal and Streptococcal Superantigen Exotoxins

Spaulding, A. R., Salgado‐Pabón, W., Kohler, P. L., Horswill, A. R., Leung, D. Y. M., & Schlievert, P. M. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00104-12 · Cited by 540 · see citing works

The Properties of Lauric Acid and Their Significance in Coconut Oil

Dayrit, F. M. (2015) · Journal of the American Oil Chemists' Society · doi:10.1007/s11746-014-2562-7 · Cited by 479 · see citing works

Methicillin Resistance in Staphylococcus Aureus: Mechanisms and Modulation

Stapleton, P. D., & Taylor, P. W. (2002) · Science Progress · doi:10.3184/003685002783238870 · Cited by 418 · see citing works

Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?

Brown, D. L. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4675 · Cited by 360 · see citing works

Composition, Structure and Absorption of Milk Lipids: A Source of Energy, Fat-Soluble Nutrients and Bioactive Molecules

German, J. B., & Dillard, C. J. (2006) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408690590957098 · Cited by 316 · see citing works

Thematic Review Series: Skin Lipids. Antimicrobial lipids at the skin surface

Drake, D. R., Brogden, K. A., Dawson, D. V., & Wertz, P. W. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r700016-jlr200 · Cited by 305 · see citing works

Saturated fats: what dietary intake?

German, J. B., & Dillard, C. J. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.3.550 · Cited by 293 · see citing works

The Staphylococcus aureus surface protein IsdA mediates resistance to innate defenses of human skin

Clarke, S. R., Mohamed, R., Bian, L., Routh, A. F., Kokai-Kun, J. F., Mond, J. J., Tarkowski, A., & Foster, S. J. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.04.005 · Cited by 225 · see citing works

The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence Implications

Kenny, J. G., Ward, D., Josefsson, E., Jonsson, I., Hinds, J., Rees, H. H., Lindsay, J. A., Tarkowski, A., & Horsburgh, M. J. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004344 · Cited by 217 · see citing works

Glycerol monolaurate antibacterial activity in broth and biofilm cultures.

Schlievert, P. M., & Peterson, M. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040350 · Cited by 198 · see citing works

Antibacterial Effect of Caprylic Acid and Monocaprylin on Major Bacterial Mastitis Pathogens

Nair, M. K. M., Joy, J., Vasudevan, P., Hinckley, L. S., Hoagland, T. A., & Venkitanarayanan, K. (2005) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(05)73033-2 · Cited by 188 · see citing works

Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteria

Preuss, H. G., Echard, B., Enig, M., Brook, I., & Elliott, T. B. (2005) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-005-6604-1 · Cited by 180 · see citing works

N -Acylhomoserine Lactones Antagonize Virulence Gene Expression and Quorum Sensing in Staphylococcus aureus

Qazi, S. N. A., Middleton, B., Muharram, S. H., Cockayne, A., Hill, P. J., O’Shea, P., Chhabra, S. R., Cámara, M., & Williams, P. M. (2006) · Infection and Immunity · doi:10.1128/iai.74.2.910-919.2006 · Cited by 170 · see citing works

In Vitro Antimicrobial Activities of Organic Acids and Their Derivatives on Several Species of Gram-Negative and Gram-Positive Bacteria

Kovanda, L. L., Zhang, W., Wei, X., Luo, J., Wu, X., Atwill, E. R., Vaessen, S. F. C., Li, X., & Liu, Y. (2019) · Molecules · doi:10.3390/molecules24203770 · Cited by 166 · see citing works

Insect Derived Lauric Acid as Promising Alternative Strategy to Antibiotics in the Antimicrobial Resistance Scenario

Borrelli, L., Varriale, L., Dipineto, L., Pace, A., Menna, L. F., & Fioretti, A. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.620798 · Cited by 159 · see citing works

Bacterial virulence as a target for antimicrobial chemotherapy

Alksne, L. E., & Projan, S. J. (2000) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(00)00155-5 · Cited by 156 · see citing works

A Review of Monolaurin and Lauric Acid: <i>Natural Virucidal and Bactericidal Agents</i>

Lieberman, S., Enig, M. G., & Preuss, H. G. (2006) · Alternative and Complementary Therapies · doi:10.1089/act.2006.12.310 · Cited by 153 · see citing works

Drug-Eluting Fibers for HIV-1 Inhibition and Contraception

Ball, C. S., Krogstad, E. A., Chaowanachan, T., & Woodrow, K. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049792 · Cited by 126 · see citing works

Antimicrobial Emulsifier–Glycerol Monolaurate Induces Metabolic Syndrome, Gut Microbiota Dysbiosis, and Systemic Low‐Grade Inflammation in Low‐Fat Diet Fed Mice

Jiang, Z., Zhao, M., Zhang, H., Yang, L., Liu, M., & Feng, F. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700547 · Cited by 125 · see citing works

Glycerol monolaurate in the diet of broiler chickens replacing conventional antimicrobials: Impact on health, performance and meat quality

Fortuoso, B. F., dos Reis, J. H., Gebert, R. R., Barreta, M., Griss, L. G., Casagrande, R. A., de Cristo, T. G., Santiani, F., Campigotto, G., Rampazzo, L., et al. (2019) · Microbial Pathogenesis · doi:10.1016/j.micpath.2019.02.005 · Cited by 120 · see citing works

Potential of complementary and alternative medicine in preventive management of novel H1N1 flu (Swine flu) pandemic: thwarting potential disasters in the bud

Arora, R., Chawla, R., Marwah, R., Arora, P., Sharma, R. K., Kaushik, V., Goel, R., Kaur, A., Silambarasan, M., Tripathi, R. P., et al. (2011) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2011/586506 · Cited by 117 · see citing works

Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression

Mitchell, G., Lafrance, M., Boulanger, S., Séguin, D. L., Guay, I., Gattuso, M., Marsault, É., Bouarab, K., & Malouin, F. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr510 · Cited by 110 · see citing works

Equivalence of Lauric Acid and Glycerol Monolaurate as Inhibitors of Signal Transduction in <i>Staphylococcus aureus</i>

Ruzin, A., & Novick, R. P. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.9.2668-2671.2000 · Cited by 105 · see citing works

Temperature regulates bacterial protein production: possible role in rosacea

Dahl, M. V., Ross, A. J., & Schlievert, P. M. (2004) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2003.05.005 · Cited by 104 · see citing works

Effects of lactic acid and lauricidin on the survival of Listeria monocytogenes, Salmonella enteritidis and Escherichia coli O157:H7 in chicken breast stored at 4 °C

Anang, D. M., Rusul, G., Bakar, J., & Ling, F. H. (2007) · Food Control · doi:10.1016/j.foodcont.2006.05.015 · Cited by 102 · see citing works

Modulation of the Gut Microbiota during High-Dose Glycerol Monolaurate-Mediated Amelioration of Obesity in Mice Fed a High-Fat Diet

Zhao, M., Jiang, Z., Cai, H., Li, Y., Mo, Q., Deng, L., Zhong, H., Liu, T., Zhang, H., Kang, J. X., et al. (2020) · mBio · doi:10.1128/mbio.00190-20 · Cited by 96 · see citing works

Glycerol Monolaurate Inhibits the Effects of Gram-Positive Select Agents on Eukaryotic Cells

Peterson, M. L., & Schlievert, P. M. (2006) · Biochemistry · doi:10.1021/bi051992u · Cited by 91 · see citing works

Distinct Roles of Phenol-Soluble Modulins in Spreading of Staphylococcus aureus on Wet Surfaces

Tsompanidou, E., Denham, E. L., Becher, D., de Jong, A., Buist, G., van Oosten, M., Manson, W. L., Back, J. W., van Dijl, J. M., & Dreisbach, A. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.03157-12 · Cited by 91 · see citing works

Influence of subinhibitory concentrations of plant essential oils on the production of enterotoxins A and B and α-toxin by Staphylococcus aureus

Smith‐Palmer, A., Stewart, J., & Fyfe, L. (2004) · Journal of Medical Microbiology · doi:10.1099/jmm.0.45567-0 · Cited by 89 · see citing works

Effect of α-linolenic, capric and lauric acid on the fatty acid biosynthesis in Staphylococcus aureus

Sado-Kamdem, S. L., Vannini, L., & Guerzoni, M. E. (2008) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2008.12.010 · Cited by 84 · see citing works

Fatty acids and monoacylglycerols inhibit growth ofStaphylococcus aureus

Kelsey, J. A., Bayles, K. W., Shafii, B., & McGuire, M. A. (2006) · Lipids · doi:10.1007/s11745-006-5048-z · Cited by 83 · see citing works

Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics

Zhang, M. S., Sandouk, A., & Houtman, J. C. D. (2016) · Scientific Reports · doi:10.1038/srep30225 · Cited by 81 · see citing works

Role of fem factors in methicillin resistance

Berger‐Bächi, B., & Tschierske, M. (1998) · Drug Resistance Updates · doi:10.1016/s1368-7646(98)80048-4 · Cited by 81 · see citing works

The polyphenol (−)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus

Shah, S., Stapleton, P. D., & Taylor, P. W. (2007) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2007.02296.x · Cited by 76 · see citing works

Requirement of the agr Locus for Colony Spreading of Staphylococcus aureus

Tsompanidou, E., Sibbald, M. J. J. B., Chlebowicz, M. A., Dreisbach, A., Back, J. W., van Dijl, J. M., Buist, G., & Denham, E. L. (2010) · Journal of Bacteriology · doi:10.1128/jb.01276-10 · Cited by 75 · see citing works

Antimicrobial lipids at the skin surface

Drake, D. R., Brogden, K. A., Dawson, D. V., & Wertz, P. W. (2008) · Journal of Lipid Research · Cited by 74 · see citing works

Glycerol Monolaurate Inhibits Candida and Gardnerella vaginalis In Vitro and In Vivo but Not Lactobacillus

Strandberg, K. L., Peterson, M. L., Lin, Y., Pack, M. C., Chase, D. J., & Schlievert, P. M. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01151-09 · Cited by 69 · see citing works

Global regulation of virulence determinants in Staphylococcus Aureus by the SarA protein family

Ambrose, L. C. (2002) · Frontiers in bioscience · doi:10.2741/cheung · Cited by 69 · see citing works

Glycerol Monolaurate Does Not Alter Rhesus Macaque ( Macaca mulatta ) Vaginal Lactobacilli and Is Safe for Chronic Use

Schlievert, P. M., Strandberg, K. L., Brosnahan, A. J., Peterson, M. L., Pambuccian, S. E., Nephew, K. R., Brunner, K. G., SCHULTZ‐DARKEN, N. J., & Haase, A. T. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00989-08 · Cited by 68 · see citing works

Short and Medium Chain Fatty Acids and Their Derivatives as a Natural Strategy in the Control of Necrotic Enteritis and Microbial Homeostasis in Broiler Chickens

Gómez-Osorio, L.-M., Yepes-Medina, V., Ballou, A. L., Parini, M., & Angel, R. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.773372 · Cited by 67 · see citing works

Glycerol‐Monolaurate‐Mediated Attenuation of Metabolic Syndrome is Associated with the Modulation of Gut Microbiota in High‐Fat‐Diet‐Fed Mice

Zhao, M., Cai, H., Jiang, Z., Li, Y., Zhong, H., Zhang, H., & Feng, F. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801417 · Cited by 67 · see citing works

Activity of virgin coconut oil, lauric acid or monolaurin in combination with lactic acid against Staphylococcus aureus.

Tangwatcharin, P., & Khopaibool, P. (2012) · PubMed · Cited by 60 · see citing works

New insights into the prevention of staphylococcal infections and toxic shock syndrome

Lin, Y., & Peterson, M. L. (2010) · Expert Review of Clinical Pharmacology · doi:10.1586/ecp.10.121 · Cited by 57 · see citing works

In Vitro and In Vivo Evaluations of the Activities of Lauric Acid Monoester Formulations against Staphylococcus aureus

Rouse, M. S., Rotger, M., Piper, K. E., Steckelberg, J. M., Scholz, M., Andrews, J., & Patel, R. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.8.3187-3191.2005 · Cited by 53 · see citing works

Coconuts and Health: Different Chain Lengths of Saturated Fats Require Different Consideration

Hewlings, S. J. (2020) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd7040059 · Cited by 56 · see citing works

Effects of Short- and Medium-Chain Fatty Acids on Production, Meat Quality, and Microbial Attributes—A Review

Szabó, R. T., Kovács-Weber, M., Zimborán, Á., Kovács, L., & Erdélyi, M. (2023) · Molecules · doi:10.3390/molecules28134956 · Cited by 52 · see citing works

Menaquinone Analogs Inhibit Growth of Bacterial Pathogens

Schlievert, P. M., Merriman, J. A., Salgado‐Pabón, W., Mueller, E. A., Spaulding, A. R., Vu, B. G., Chuang-Smith, O. N., Kohler, P. L., & Kirby, J. R. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01279-13 · Cited by 52 · see citing works

Effects of Essential Oils and Monolaurin onStaphylococcus aureus:In VitroandIn VivoStudies

Preuss, H. G., Echard, B. W., Dadgar, A., Talpur, N. A., Manohar, V., Enig, M. G., Bagchi, D., & Ingram, C. (2005) · Toxicology Mechanisms and Methods · doi:10.1080/15376520590968833 · Cited by 50 · see citing works

Glycerol Monolaurate and Dodecylglycerol Effects on Staphylococcus aureus and Toxic Shock Syndrome Toxin-1 In Vitro and In Vivo

Lin, Y., Schlievert, P. M., Anderson, M. J., Fair, C. L., Schaefers, M. M., Muthyala, R., & Peterson, M. L. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007499 · Cited by 50 · see citing works

Bacterial energetics and antimicrobial resistance

Proctor, R. A., & von Humboldt, A. (1998) · Drug Resistance Updates · doi:10.1016/s1368-7646(98)80003-4 · Cited by 49 · see citing works

Glycerol Monolaurate Inhibits Virulence Factor Production in Bacillus anthracis

Vetter, S. M., & Schlievert, P. M. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.4.1302-1305.2005 · Cited by 49 · see citing works

The Natural Antimicrobial Peptide Subtilosin Acts Synergistically with Glycerol Monolaurate, Lauric Arginate, and ε-Poly- l -Lysine against Bacterial Vaginosis-Associated Pathogens but Not Human Lactobacilli

Noll, K. S., Prichard, M. N., Khaykin, A., Sinko, P. J., & Chikindas, M. L. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05861-11 · Cited by 48 · see citing works

Detecting the quality of glycerol monolaurate: A method for using Fourier transform infrared spectroscopy with wavelet transform and modified uninformative variable elimination

Chen, X., Wu, D., He, Y., & Liu, S. (2009) · Analytica Chimica Acta · doi:10.1016/j.aca.2009.02.002 · Cited by 43 · see citing works

Evaluation of antimicrobial activity of glycerol monolaurate nanocapsules against American foulbrood disease agent and toxicity on bees

Lopes, L. Q. S., Santos, C. G., Vaucher, R. D. A., Gende, L. B., Raffin, R. P., & Santos, R. C. V. (2016) · Microbial Pathogenesis · doi:10.1016/j.micpath.2016.05.014 · Cited by 43 · see citing works

Synergistic interactions between antimicrobial peptides derived from plectasin and lipid nanocapsules containing monolaurin as a cosurfactant against Staphylococcus aureus

Umerska, A. M., Cassisa, V., Bastiat, G., Matougui, N., Nehme, H., Manero, F., Eveillard, M., & Saulnier, P. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s139625 · Cited by 43 · see citing works

Medicinal Plants Used in the Treatment of Influenza A Virus Infections

Adetunji, C. O., Ajayi, O. O., Akram, M., Olaniyan, O. T., Chishti, M. A., Inobeme, A., Olaniyan, S., Adetunji, J. B., Olaniyan, M. F., & Samson, A. O. (2021) · Springer eBooks · doi:10.1007/978-981-33-6850-7_19 · Cited by 42 · see citing works

Inactivation of Escherichia coli O157:H7 and Salmonella spp. on alfalfa seeds by caprylic acid and monocaprylin

Chang, S.-S., Redondo-Solano, M., & Thippareddi, H. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.09.011 · Cited by 41 · see citing works

The effect of skin fatty acids on Staphylococcus aureus

Neumann, Y., Ohlsen, K., Donat, S., Engelmann, S., Kusch, H., Albrecht, D., Cartron, M. L., Hurd, A. F., & Foster, S. J. (2014) · Archives of Microbiology · doi:10.1007/s00203-014-1048-1 · Cited by 42 · see citing works

Antimicrobial synergy of monolaurin lipid nanocapsules with adsorbed antimicrobial peptides against Staphylococcus aureus biofilms in vitro is absent in vivo

Rozenbaum, R. T., Su, L., Umerska, A. M., Eveillard, M., Håkansson, J., Mahlapuu, M., Huang, F., Liu, J., Zhang, Z., Shi, L., et al. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.11.018 · Cited by 42 · see citing works

In vitroantimicrobial activity and mechanism of action of novel carbohydrate fatty acid derivatives againstStaphylococcus aureusand MRSA

Nobmann, P., Bourke, P., Dunne, J., & HENEHAN, G. T. M. (2009) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2009.04622.x · Cited by 41 · see citing works

Evaluation of monolaurin from camphor tree seeds for controlling food spoilage fungi

Luo, C., Zeng, Z., Gong, D., Zhao, C., Liang, Q., & Zeng, C. C. (2014) · Food Control · doi:10.1016/j.foodcont.2014.06.017 · Cited by 41 · see citing works

Regulation of the Expression of Cell Wall Stress Stimulon Member GenemsrA1in Methicillin-Susceptible or -ResistantStaphylococcus aureus

Pechous, R. D., Ledala, N., Wilkinson, B. J., & Jayaswal, R. K. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.8.3057-3063.2004 · Cited by 41 · see citing works

Effects of added phenolics on the storage stability of avocado and coconut oils

Sun‐Waterhouse, D., Thakorlal, J., & Zhou, J. (2011) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2011.02655.x · Cited by 38 · see citing works

Glycerol Monolaurate Microbicide Protection against Repeat High-Dose SIV Vaginal Challenge

Haase, A. T., Rakasz, E. G., SCHULTZ‐DARKEN, N. J., Nephew, K. R., Weisgrau, K. L., Reilly, C., Li, Q., Southern, P. J., Rothenberger, M. K., Peterson, M. L., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129465 · Cited by 38 · see citing works

Modulatory effects of medium chain fatty acids in poultry nutrition and health

Çenesiz, A. A., & Çiftçi, İ. (2020) · World s Poultry Science Journal · doi:10.1080/00439339.2020.1739595 · Cited by 38 · see citing works

Effects of α-glyceryl monolaurate on growth, immune function, volatile fatty acids, and gut microbiota in broiler chickens

Lan, J., Chen, G., Cao, G., Tang, J., Li, Q., Zhang, B., & Yang, C. (2020) · Poultry Science · doi:10.1016/j.psj.2020.11.052 · Cited by 37 · see citing works

Staphylococcal Pathogenesis and Pathogenicity Factors: Genetics and Regulation

Novick, R. P. (2014) · ASM Press eBooks · doi:10.1128/9781555816513.ch41 · Cited by 37 · see citing works

Glycerol Monolaurate Inhibits Induction of Vancomycin Resistance in Enterococcus faecalis

Ruzin, A. V., & Novick, R. P. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.1.182-185.1998 · Cited by 37 · see citing works

Characterization of Monolaurin Resistance in Enterococcus faecalis

Dufour, M., Manson, J. M., Bremer, P. J., Dufour, J., Cook, G. M., & Simmonds, R. S. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.01013-07 · Cited by 35 · see citing works

Reduction inStaphylococcus aureusGrowth and Exotoxin Production and in Vaginal Interleukin 8 Levels Due to Glycerol Monolaurate in Tampons

Strandberg, K. L., Peterson, M. L., Schaefers, M. M., Case, L. C., Pack, M. C., Chase, D. J., & Schlievert, P. M. (2009) · Clinical Infectious Diseases · doi:10.1086/644614 · Cited by 34 · see citing works

Bioactive monolaurin as an antimicrobial and its potential to improve the immune system and against COVID-19: a review

Subroto, E., & Indiarto, R. (2020) · Food Research · doi:10.26656/fr.2017.4(6).324 · Cited by 35 · see citing works

Milk-derived anti-infectives and their potential to combat bacterial and viral infection

Morrin, S. T., Buck, R. H., Farrow, M., & Hickey, R. M. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104442 · Cited by 34 · see citing works

Antibacterial activities of dendritic amphiphiles against nontuberculous mycobacteria

Falkinham, J. O., Macri, R. V., Maisuria, B. B., Actis, M. L., Sugandhi, E. W., Williams, A. A., Snyder, A. V., Jackson, F. R., Poppe, M. A., Chen, L., et al. (2011) · Tuberculosis · doi:10.1016/j.tube.2011.12.002 · Cited by 33 · see citing works

Inactivation of bacterial fish pathogens by medium-chain lipid molecules (caprylic acid, monocaprylin and sodium caprylate)

Johny, A. K., Vasudevan, P., Nair, M. K. M., Hoagland, T. A., & Venkitanarayanan, K. (2007) · Aquaculture Research · doi:10.1111/j.1365-2109.2007.01799.x · Cited by 31 · see citing works

Comparing micellar, hemolytic, and antibacterial properties of di- and tricarboxyl dendritic amphiphiles

Maisuria, B. B., Actis, M. L., Hardrict, S. N., Falkinham, J. O., Cole, M. F., Cihlar, R. L., Peters, S. M., Macri, R. V., Sugandhi, E. W., Williams, A. A., et al. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.03.036 · Cited by 29 · see citing works

Health and nutritional benefits from coconut oil and its advantages over competing oils.

Enig, M. G. (2010) · Inḍiyan Nāḷikēra Jēṇal · Cited by 29 · see citing works

Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters

Zhang, M. S., Tran, P. M., Wolff, A. J., Tremblay, M. M., Fosdick, M. G., & Houtman, J. C. D. (2018) · Science Signaling · doi:10.1126/scisignal.aam9095 · Cited by 29 · see citing works

In vitro antagonistic inhibitory effects of palm seed crude oils and their main constituent, lauric acid, with oxacillin in Staphylococcus aureus

Laloučková, K., Skřivanová, E., Rondevaldová, J., Fraňková, A., Soukup, J., & Kokoška, L. (2021) · Scientific Reports · doi:10.1038/s41598-020-80481-0 · Cited by 26 · see citing works

Staphylococcus aureus

Park, J. Y., & Seo, K. S. (2019) · ASM Press eBooks · doi:10.1128/9781555819972.ch21 · Cited by 26 · see citing works

Proteolytic cleavage of the repressor (BlaI) of β-lactamase synthesis inStaphylococcus aureus

Lewis, R. A., Curnock, S. P., & Dyke, K. G. H. (1999) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1999.tb08687.x · Cited by 26 · see citing works

Autophagy Subversion by Bacteria

Campoy, E., & Colombo, M. I. (2009) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-00302-8_11 · Cited by 25 · see citing works

Factors affecting methicillin resistance in Staphylococcus aureus

Berger‐Bächi, B. (1995) · International Journal of Antimicrobial Agents · doi:10.1016/0924-8579(95)00021-y · Cited by 24 · see citing works

In vitro and in vivo inhibition of Helicobacter pylori by Lactobacillus plantarum pH3A, monolaurin, and grapefruit seed extract

Kang, S., Guo, Y., Rao, J., Jin, H. Z., You, H. J., & Ji, G. E. (2021) · Food & Function · doi:10.1039/d1fo01480c · Cited by 23 · see citing works

Glycerol Monolaurate (GML) and a Nonaqueous Five-Percent GML Gel Kill <i>Bacillus</i> and <i>Clostridium</i> Spores

Schlievert, P. M., Kilgore, S. H., Kaus, G. M., Ho, T. D., & Ellermeier, C. D. (2018) · mSphere · doi:10.1128/mspheredirect.00597-18 · Cited by 21 · see citing works

Monolaurin Confers a Protective Effect Against Porcine Epidemic Diarrhea Virus Infection in Piglets by Regulating the Interferon Pathway

Zhang, Q., Yi, D., Ji, C., Wu, T., Wang, M., Guo, S., Wang, L., Zhao, D., & Hou, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.797476 · Cited by 20 · see citing works

The Natural Surfactant Glycerol Monolaurate Significantly Reduces Development of Staphylococcus aureus and Enterococcus faecalis Biofilms

Hess, D. J., Henry‐Stanley, M. J., & Wells, C. L. (2015) · Surgical Infections · doi:10.1089/sur.2014.162 · Cited by 20 · see citing works

Novel Antimicrobial Peptides That Inhibit Gram Positive Bacterial Exotoxin Synthesis

Merriman, J. A., Nemeth, K. A., & Schlievert, P. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095661 · Cited by 18 · see citing works

Surfactants, Aromatic and Isoprenoid Compounds, and Fatty Acid Biosynthesis Inhibitors Suppress Staphylococcus aureus Production of Toxic Shock Syndrome Toxin 1

McNamara, P. J., Syverson, R. E., Milligan-Myhre, K., Фролова, О. С., Schroeder, S., Kidder, J. M., Hoang, T., & Proctor, R. A. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01293-08 · Cited by 18 · see citing works

Human Serum Albumin (HSA) Suppresses the Effects of Glycerol Monolaurate (GML) on Human T Cell Activation and Function

Zhang, M. S., & Houtman, J. C. D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0165083 · Cited by 16 · see citing works

Fatty acid profile of coconut oil in relation to nut maturity and season in selected cultivars/hybrids

Azeez, S. (2007) · British Food Journal · doi:10.1108/00070700710736525 · Cited by 15 · see citing works

Dietary Alpha-Monolaurin for Nile Tilapia (Oreochromis niloticus): Stimulatory Effects on Growth, Immunohematological Indices, and Immune-Related Gene Expressions

Ali, M. M., Elashry, M. A., Mohammady, E. Y., Soaudy, M. R., El-Garhy, H. A. S., El-Erian, M. A., Mustafa, A., Abouelsoud, M., Ragaza, J. A., El‐Haroun, E., et al. (2023) · Aquaculture Research · doi:10.1155/2023/3155447 · Cited by 15 · see citing works

Nutrition and Health Aspects of Coconut

Rajamohan, T., & Archana, U. (2018) · Springer eBooks · doi:10.1007/978-981-13-2754-4_15 · Cited by 15 · see citing works

Biological Control of Pyricularia oryzae Using Antifungal Compounds Produced by Aspergillus niger

Idan, A. A., Sijam, K., Kadir, J., Rashid, T. S., Awla, H. K., & Alsultan, W. (2017) · American Journal of Plant Sciences · doi:10.4236/ajps.2017.810166 · Cited by 12 · see citing works

In vitro susceptibility of swine pathogens to feed additives and active ingredients with potential as antibiotic replacements

Neath, C. E. E., Portocarero, N., & Jones, C. (2021) · Journal of Applied Microbiology · doi:10.1111/jam.15318 · Cited by 12 · see citing works

Fetal Brain Damage during Maternal COVID-19: Emerging Hypothesis, Mechanism, and Possible Mitigation through Maternal-Targeted Nutritional Supplementation

Germano, C., Messina, A., Tavella, E., Vitale, R., Avellis, V., Barboni, M., Attini, R., Revelli, A., Zola, P., Manzoni, P., et al. (2022) · Nutrients · doi:10.3390/nu14163303 · Cited by 12 · see citing works

Chitosan Malate Inhibits Growth and Exotoxin Production of Toxic Shock Syndrome-Inducing Staphylococcus aureus Strains and Group A Streptococci

Schlievert, P. M. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01295-06 · Cited by 12 · see citing works

In vitro antimicrobial properties of caprylic acid, monocaprylin, and sodium caprylate against Dermatophilus congolensis

Valipe, S. R., Nadeau, J., Annamali, T., Venkitanarayanan, K., & Hoagland, T. A. (2011) · American Journal of Veterinary Research · doi:10.2460/ajvr.72.3.331 · Cited by 11 · see citing works

Antiviral Potential of Coconut (Cocos nucifera L.) Oil and COVID-19

Ramesh, S. V., Pandiselvam, R., Hebbar, K. B., Manikantan, M. R., Shameena Beegum, P. P., Praveen, S., & Sruthi, N. U. (2020) · Coronaviruses · doi:10.2174/2666796701999201104164010 · Cited by 11 · see citing works

Effect of Dietary Inclusion of Alpha-Monolaurin on the Growth Performance, Lipid Peroxidation, and Immunity Response in Broilers

Saleh, A. A., El-Gharabawy, B., Hassan, A. M., Badawi, N. A., Eid, Y. Z., Selim, S., Shukry, M., & Dawood, M. A. O. (2021) · Sustainability · doi:10.3390/su13095231 · Cited by 12 · see citing works

Regulation of β-Lactamase Synthesis as a Novel Site of Action for Suppression of Methicillin Resistance in Staphylococcus aureus

Bruns, O., Bruns, W., & Pulverer, G. (1997) · Zentralblatt für Bakteriologie · doi:10.1016/s0934-8840(97)80008-4 · Cited by 11 · see citing works

Glycerol Monolaurate Inhibits Induction of Vancomycin Resistance in Enterococcus faecalis

Ruzin, A. V., & Novick, R. P. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.1.182-185.1998 · Cited by 37 · see citing works

Equivalence of Lauric Acid and Glycerol Monolaurate as Inhibitors of Signal Transduction in <i>Staphylococcus aureus</i>

Ruzin, A., & Novick, R. P. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.9.2668-2671.2000 · Cited by 105 · see citing works

Glycerol Monolaurate Inhibits the Effects of Gram-Positive Select Agents on Eukaryotic Cells

Peterson, M. L., & Schlievert, P. M. (2006) · Biochemistry · doi:10.1021/bi051992u · Cited by 91 · see citing works

Glycerol monolaurate and dodecylglycerol effects on Staphylococcus aureus and toxic shock syndrome toxin-1 in vitro and in vivo. PLoS One 2009

Lin, Y.-C., Schlievert, P. M., Anderson, M. J., Fair, C. L., Schaefers, M. M., Muthyala, R., & Peterson, M. L. (2016)

The effect of glycerol monolaurate on growth of, and production of Toxic Shock Syndrome Toxin-1 and lipase by, Staphylococcus aureus

Holland, K. T., Taylor, D., & Farrell, A. M. (1994) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/33.1.41 · Cited by 19 · see citing works