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Kinetics of Virus-Specific CD8+T Cells and the Control of Human Immunodeficiency Virus Infection
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Several primate models indicate that cytotoxic T lymphocyte-inducing vaccines may be unable to prevent human immunodeficiency virus infection but may have a long-term benefit in controlling viral replication and delaying disease progression. Here we show that analysis of the kinetics of antigen-specific CD8+T-cell expansion suggests a delay in activation following infection that allows unimpeded early viral replication. Viral kinetics do not differ between controls and vaccinees during this delay phase. An increase in virus-specific CD8+T-cell numbers around day 10 postinfection coincides with a slowing in viral replication in vaccinees and reduces peak viral loads by around 1 log. However, this response is too little too late to prevent establishment of persistent infection.
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“Studies of the ability of memory T cells to control viral and bacterial growth suggest that both CD4+ T cells (in murine tuberculosis42) and CD8+ T cells (in simian immunodeficiency virus infection of macaques43,44) require an extended period of infection (7–10 days) before they are mobilized to control pathogen replication.”
From Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection (2021) · cites this paper as [43]
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Prognosis in HIV-1 Infection Predicted by the Quantity of Virus in Plasma
Mellors, J. W., Rinaldo, C. R., Gupta, P., White, R. M., Todd, J. A., & Kingsley, L. (1996) · Science · doi:10.1126/science.272.5265.1167 · Cited by 2,658
Koup, R. A., Safrit, J. T., Cao, Y., Andrews, C. A., McLeod, G. X., Borkowsky, W., Farthing, C., & Ho, D. D. (1994) · Journal of Virology · doi:10.1128/jvi.68.7.4650-4655.1994 · Cited by 2,494
Control of Viremia in Simian Immunodeficiency Virus Infection by CD8 + Lymphocytes
Schmitz, J. E., Kuroda, M. J., Santra, S., Sasseville, V. G., Simon, M. A., Lifton, M. A., Rácz, P., Tenner‐Racz, K., Dalesandro, M. R., Scallon, B. J., et al. (1999) · Science · doi:10.1126/science.283.5403.857 · Cited by 2,167
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
Chun, T.-W., Carruth, L., Finzi, D., Shen, X., DiGiuseppe, J. A., Taylor, H., Hermankova, M., Chadwick, K., Margolick, J., Quinn, T. C., et al. (1997) · Nature · doi:10.1038/387183a0 · Cited by 2,050
Borrow, P., Lewicki, H. A., Hahn, B. H., Shaw, G. M., & Oldstone, M. B. A. (1994) · Journal of Virology · doi:10.1128/jvi.68.9.6103-6110.1994 · Cited by 1,880
Wherry, E. J., Blattman, J. N., Murali‐Krishna, K., der Most, R. G. V., & Ahmed, R. (2003) · Journal of Virology · doi:10.1128/jvi.77.8.4911-4927.2003 · Cited by 1,645
Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory
Shedlock, D. J., & Shen, H. (2003) · Science · doi:10.1126/science.1082305 · Cited by 1,450
Jin, X., Bauer, D. E., Tuttleton, S., Lewin, S. R., Gettie, A., Blanchard, J., Irwin, C. E., Safrit, J. T., Mittler, J. E., Weinberger, L. S., et al. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.6.991 · Cited by 1,409
Self-citationDefective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help
Sun, J. C., & Bevan, M. J. (2003) · Science · doi:10.1126/science.1083317 · Cited by 1,213
Shiver, J. W., Fu, T., Chen, L., Casimiro, D. R., Davies, M.-E., Evans, R. K., Zhang, Z., Simon, A. J., Trigona, W. L., Dubey, S. A., et al. (2002) · Nature · doi:10.1038/415331a · Cited by 1,173
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Haase, A. T. (2005) · Nature reviews. Immunology · doi:10.1038/nri1706 · Cited by 436
Blanchet, F. P., Moris, A., Nikolic, D. S., Lehmann, M., Cardinaud, S., Stalder, R., Garcia, E., Dinkins, C., Leuba, F., Wu, L. J., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.04.011 · Cited by 307
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Perelson, A. S., & Ribeiro, R. M. (2013) · BMC Biology · doi:10.1186/1741-7007-11-96 · Cited by 293
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Cromer, D., Juno, J. A., Khoury, D., Reynaldi, A., Wheatley, A. K., Kent, S. J., & Davenport, M. P. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00550-x · Cited by 265
Self-citationRibeiro, R. M., Li, Q., Chavez, L. L., Li, D., Self, S. G., & Perelson, A. S. (2010) · Journal of Virology · doi:10.1128/jvi.00127-10 · Cited by 237
Self-citationEstes, J. D., Li, Q., Reynolds, M. R., Wietgrefe, S. W., Duan, L., Schacker, T. W., Picker, L. J., Watkins, D. I., Lifson, J. D., Reilly, C., et al. (2006) · The Journal of Infectious Diseases · doi:10.1086/500368 · Cited by 237
Post-treatment control of HIV infection
Conway, J. M., & Perelson, A. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1419162112 · Cited by 227
Self-citationThe role of models in understanding CD8+ T-cell memory
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Self-citationReynolds, M. R., Rakasz, E., Skinner, P. J., White, C., Abel, K., Ma, Z.-M., Compton, L., Napoé, G., Wilson, N., Miller, C. J., et al. (2005) · Journal of Virology · doi:10.1128/jvi.79.14.9228-9235.2005 · Cited by 168
Kent, S. J., Khoury, D. S., Reynaldi, A., Juno, J. A., Wheatley, A. K., Stadler, E., John Wherry, E., Triccas, J., Sasson, S. C., Cromer, D., et al. (2022) · Nature Reviews Immunology · doi:10.1038/s41577-022-00716-1 · Cited by 139
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Turnbull, E. L., Wong, M., Wang, S., Wei, X., Jones, N., Conrod, K. E., Aldam, D., Turner, J., Pellegrino, P., Keele, B. F., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803658 · Cited by 95
Dorrell, L., Yang, H., Ondondo, B., Dong, T., di Gleria, K., Suttill, A., Conlon, C. P., Brown, D., Williams, P., Bowness, P., et al. (2006) · Journal of Virology · doi:10.1128/jvi.80.10.4705-4716.2006 · Cited by 85
Jones, L., & Perelson, A. S. (2005) · Bulletin of Mathematical Biology · doi:10.1016/j.bulm.2005.01.006 · Cited by 83
Self-citationThe T cell repertoire in infection and vaccination: implications for control of persistent viruses
Davenport, M. P., Price, D. A., & McMichael, A. J. (2007) · Current Opinion in Immunology · doi:10.1016/j.coi.2007.04.001 · Cited by 65
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de Boer, R. J. (2007) · Journal of Virology · doi:10.1128/jvi.01914-06 · Cited by 64
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Ganusov, V. V., & de Boer, R. J. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020024 · Cited by 61
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Asquith, B., & McLean, A. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700666104 · Cited by 61
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Tan, H.-X., Wheatley, A. K., Esterbauer, R., Jegaskanda, S., Glass, J. J., Masopust, D., Rose, R. D., & Kent, S. J. (2017) · Mucosal Immunology · doi:10.1038/mi.2017.89 · Cited by 55
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Le, D., Miller, J. D., & Ganusov, V. V. (2015) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2014.00177 · Cited by 55
Althaus, C. L., & de Boer, R. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016468 · Cited by 51
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Loh, L., Petravic, J., Batten, C. J., Davenport, M. P., & Kent, S. J. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.0040012 · Cited by 51
Self-citationHIV vaccines: progress to date.
Munier, C. M. L., Andersen, C., & Kelleher, A. D. (2011) · PubMed · doi:10.2165/11585400-000000000-00000 · Cited by 52
Kijak, G. H., Sanders‐Buell, E., Chenine, A.-L., Eller, M. A., Goonetilleke, N. P., Thomas, R., Leviyang, S., Harbolick, E. A., Bose, M., Pham, P. T., et al. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006510 · Cited by 49
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Smith, M. Z., Fernandez, C. S., Chung, A. W., Dale, C. J., Rose, R. D., Lin, J., Brööks, A. G., Krebs, K. C., Watkins, D. I., O’Connor, D. H., et al. (2005) · Journal of Medical Primatology · doi:10.1111/j.1600-0684.2005.00126.x · Cited by 47
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Self-citationAbdel‐Motal, U. M., Gillis, J. M., Manson, K. H., Wyand, M. S., Montefiori, D. C., Stefano-Cole, K., Montelaro, R. C., Altman, J. D., & Johnson, R. P. (2005) · Virology · doi:10.1016/j.virol.2004.12.030 · Cited by 38
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Metadata
- Authors
- Davenport, M. P., Ribeiro, R. M., & Perelson, A. S.
- Affiliations
- UNSW Sydney (AU)
- Los Alamos National Laboratory (US)
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 2004-09-15
- Volume
- 78
- Issue
- 18
- Pages
- 10096-10103
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- PMC
- PMC515020
- OpenAlex
- W2093889144
- Cited by
- 101
- References
- 61
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 5 · 2019: 5 · 2018: 4 · 2017: 5 · 2016: 4 · 2015: 8 · 2014: 2 · 2013: 3 · 2012: 5
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Virology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Energy (W-7405, W-7405-ENG-36)
- James S. McDonnell Foundation
- National Institutes of Health (AI28433)
- National Institute of Allergy and Infectious Diseases (R37AI028433, AI28433, R01AI028433)
- National Center for Research Resources (RR 06555, R01RR006555)
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and Retrovirus Studies
- Keywords
- HIV infection, CD8+ T cells, cytotoxic T lymphocytes, vaccine-induced immunity, viral replication kinetics, viral load, persistent infection, HIV vaccine efficacy, disease progression
- MeSH terms
- Animals, Humans, Kinetics, Macaca mulatta, Time Factors, Virus Replication, Simian Immunodeficiency Virus, HIV-1, HIV Infections, Gene Products, gag, Immunodominant Epitopes, Simian Acquired Immunodeficiency Syndrome, AIDS Vaccines, CD8-Positive T-Lymphocytes, SAIDS Vaccines
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