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NFX1 Interacts with mSin3A/Histone Deacetylase To Repress hTERT Transcription in Keratinocytes
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“The continued passage of E6-expressing cells was shown to enhance this acetylation, whereas the knockdown of E6AP was shown to decrease the effect [253,254]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [254]
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Active Genes Are Tri-Methylated at K4 of Histone H3
Santos-Rosa, H., Schneider, R., Bannister, A. J., Sherriff, J., Bernstein, B. E., Emre, N. C. T., Schreiber, S. L., Mellor, J., & Kouzarides, T. (2002) · Nature · doi:10.1038/nature01080 · Cited by 2,138
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“Maintenance of telomere length by telomerase is required for sustained cell proliferation, and activation of telomerase is a critical step during cellular immortalization and malignant transformation (7).”
BackgroundDirect activation of TERT transcription by c-MYC
Wu, K.-J., Grandori, C., Amacker, M., Simon-Vermot, N., Polack, A., Lingner, J., & Dalla-Favera, R. (1999) · Nature Genetics · doi:10.1038/6010 · Cited by 893
Self-citationGewin, L., Myers, H., Kiyono, T., & Galloway, D. A. (2004) · Genes & Development · doi:10.1101/gad.1214704 · Cited by 277
Self-citationHorikawa, I., & Barrett, J. C. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg085 · Cited by 211
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Cited by
Basukala, O., & Banks, L. (2021) · Viruses · doi:10.3390/v13101892 · Cited by 137
The role of telomeres in the ageing of human skin: Telomeres and skin ageing
Buckingham, E. M., & Klingelhutz, A. J. (2011) · Experimental Dermatology · doi:10.1111/j.1600-0625.2010.01242.x · Cited by 109
E3 ubiquitin ligases and human papillomavirus-induced carcinogenesis
Lou, Z., & Wang, S. (2014) · Journal of International Medical Research · doi:10.1177/0300060513506655 · Cited by 22
Metadata
- Authors
- Xu, M., Luo, W., Elzi, D. J., Grandori, C., & Galloway, D. A.
- Affiliations
- Divisions of Human Biology
- Basic Sciences, Fred Hutchinson Cancer Research Center
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 2008-08
- Volume
- 28
- Issue
- 15
- Pages
- 4819-4828
- ISSN
- 1098-5549
- Cited by
- 68
- References
- 5
- Language
- en
- Update notices
- correction (2008-09-15)
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- CoChat. (2026). Citation check: NFX1 Interacts with mSin3A/Histone Deacetylase To Repress hTERT Transcription in Keratinocytes. https://app.cochat.ai/papers/10.1128/mcb.01969-07
- The paper
- Xu, M., Luo, W., Elzi, D. J., Grandori, C., & Galloway, D. A. (2008). NFX1 Interacts with mSin3A/Histone Deacetylase To Repress hTERT Transcription in Keratinocytes. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.01969-07
