Alterations in Differentiation and Behavior of Monocytic Phagocytes in Transgenic Mice that Express Dominant Suppressors of ras Signaling

<i>ras</i> GENES

Barbacid, M. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.004023 · Cited by 3,885 · see citing works

Altering the Genome by Homologous Recombination

Capecchi, M. R. (1989) · Science · doi:10.1126/science.2660260 · Cited by 2,037 · see citing works

Mammalian Ras interacts directly with the serine/threonine kinase Raf.

Vojtek, A., Hollenberg, S., & Cooper, J. A. (1993) · Cell · doi:10.1016/0092-8674(93)90307-c · Cited by 1,971 · see citing works

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

Yoshida, H., Hayashi, S.-I., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T., Shultz, L. D., & Nishikawa, S.-I. (1990) · Nature · doi:10.1038/345442a0 · Cited by 1,789 · see citing works

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

Lowenstein, E. J., Daly, R. J., Batzer, A., Li, W., Margolis, B. L., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar‐Sagi, D., & Schlessinger, J. (1992) · Cell · doi:10.1016/0092-8674(92)90167-b · Cited by 1,632 · see citing works

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

Austyn, J. M., & Gordon, S. (1981) · European Journal of Immunology · doi:10.1002/eji.1830111013 · Cited by 1,580 · see citing works

Peptide Growth Factors and Their Receptors

Arai, K., Battey, J. F., Sporn, M. B., & Roberts, A. B. (1991) · Medical Entomology and Zoology · Cited by 1,225 · see citing works

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Egan, S. E., Giddings, B. W., Brooks, M. W., Buday, L., Sizeland, A. M., & Weinberg, R. A. (1993) · Nature · doi:10.1038/363045a0 · Cited by 1,200 · see citing works

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

Buday, L., & Downward, J. (1993) · Cell · doi:10.1016/0092-8674(93)90146-h · Cited by 1,064 · see citing works

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

Rozakis-Adcock, M., Fernley, R. T., Wade, J. D., Pawson, T. J., & Bowtell, D. D. L. (1993) · Nature · doi:10.1038/363083a0 · Cited by 1,009 · see citing works

Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase

Moodie, S. A., Willumsen, B. M., Weber, M. J., & Wolfman, A. (1993) · Science · doi:10.1126/science.8503013 · Cited by 968 · see citing works

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase

Simon, M. A., Bowtell, D. D. L., Dodson, G. S., Laverty, T., & Rubin, G. M. (1991) · Cell · doi:10.1016/0092-8674(91)90065-7 · Cited by 860 · see citing works

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

Zhang, X., Settleman, J. E., Kyriakis, J. M., Takeuchi-Suzuki, E., Elledge, S. J., Marshall, M. S., Bruder, J. T., Rapp, U. R., & Avruch, J. (1993) · Nature · doi:10.1038/364308a0 · Cited by 859 · see citing works

Stimulation of p21ras upon T-cell activation

Downward, J., Graves, J. D., Warne, P. H., Rayter, S., & Cantrell, D. A. (1990) · Nature · doi:10.1038/346719a0 · Cited by 841 · see citing works

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

Clark, S. G., Stern, M., & Horvritz, H. R. (1992) · Nature · doi:10.1038/356340a0 · Cited by 603 · see citing works

The pathway to signal achievement

Egan, S. E., & Weinberg, R. A. (1993) · Nature · doi:10.1038/365781a0 · Cited by 560 · see citing works

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes.

Estreicher, A., Mühlhauser, J., Carpentier, J. L., Orci, L., & Vassalli, J. D. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.111.2.783 · Cited by 469 · see citing works

MACROPHAGE COLONY STIMULATING FACTOR RESTORESIN VIVOBONE RESORPTION IN THEOP/OPOSTEOPETROTIC MOUSE

Felix, R., Cecchini, M. G., & Fleisch, H. A. (1990) · Endocrinology · doi:10.1210/endo-127-5-2592 · Cited by 441 · see citing works

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

Beitel, G. J., Clark, S. G., & Horvitz, H. (1990) · Nature · doi:10.1038/348503a0 · Cited by 414 · see citing works

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.

Farr, C. J., Saiki, R. K., Erlich, H. A., McCormick, F. P., & Marshall, C. J. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.5.1629 · Cited by 355 · see citing works

Raf functions downstream of Rasl in the Sevenless signal transduction pathway

Dickson, B. J., Sprenger, F., Morrison, D. K., & Hafen, E. (1992) · Nature · doi:10.1038/360600a0 · Cited by 312 · see citing works

Osteopetrosis, a New Recessive Skeletal Mutation on Chromosome 12 of the Mouse

Marks, S. C., & LANE, P. W. (1976) · Journal of Heredity · doi:10.1093/oxfordjournals.jhered.a108657 · Cited by 310 · see citing works

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras.

Bowtell, D. D. L., Fu, P., Simon, M., & Senior, P. V. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.14.6511 · Cited by 287 · see citing works

C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation

Han, M., Golden, A., Han, Y., & Sternberg, P. W. (1993) · Nature · doi:10.1038/363133a0 · Cited by 271 · see citing works

Delayed hematopoietic development in osteopetrotic (op/op) mice.

Begg, S. K., Radley, J., Pollard, J. W., Chisholm, O., Stanley, E. R., & Bertoncello, I. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.177.1.237 · Cited by 194 · see citing works

Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor.

Wiktor-Jędrzejczak, W., Urbanowska, E., Aukerman, S. L., Pollard, J. W., Stanley, E. R., Ralph, P., Ansari, A. A., Sell, K. W., & Szperl, M. (1991) · PubMed · Cited by 176 · see citing works

A C‐terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

Marshall, M. S., Hill, W. S., Ng, A. S., Vogel, U. S., Schaber, M. D., Scolnick, E. M., Dixon, R. A., Sigal, I. S., & Gibbs, W. W. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03480.x · Cited by 159 · see citing works

Mitogenic Signaling By Colony-Stimulating Factor 1 and ras Is Suppressed by the ets-2 DNA-Binding Domain and Restored by myc Overexpression

Langer, S. J., Bortner, D. M., Roussel, M. F., Sherr, C. J., & Ostrowski, M. C. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.12.5355-5362.1992 · Cited by 146 · see citing works

NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation

Qiu, M. S., & Green, S. H. (1991) · Neuron · doi:10.1016/0896-6273(91)90339-2 · Cited by 146 · see citing works

Macrophage colony stimulating factor (M-CSF) is essential for osteoclast formation in vitro

Hattersley, G., Owens, J., Flanagan, A. M., & Chambers, T. J. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)92015-c · Cited by 137 · see citing works

Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.

Reddy, M. A., Yang, B. S., Yue, X., Barnett, C. J., Ross, I. L., Sweet, M. J., Hume, D. A., & Ostrowski, M. C. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.6.2309 · Cited by 123 · see citing works

Shc, Grb2, Sosl, and a 150-Kilodalton Tyrosine-Phosphorylated Protein Form Complexes with Fms in Hematopoietic Cells

Lioubin, M. N., Myles, G. M., Carlberg, K., Bowtell, D. D. L., & Rohrschneider, L. R. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.5682-5691.1994 · Cited by 117 · see citing works

CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages.

Wiktor-Jędrzejczak, W., Ratajczak, M. Z., Ptasznik, A., Sell, K. W., Ahmed‐Ansari, A., & Ostertag, W. (1992) · PubMed · Cited by 114 · see citing works

Mechanisms of ras mutation in myelodysplastic syndrome.

Yunis, J. J., Boot, A. J., Mayer, M.-C., et al. (1989) · PubMed · Cited by 99 · see citing works

Transcription of the human colony-stimulating factor-1 receptor gene is regulated by separate tissue-specific promoters

Roberts, W., Shapiro, L., Ashmun, R., & Look, A. T. (1992) · Blood · doi:10.1182/blood.v79.3.586.586 · Cited by 70 · see citing works

Transgenic mice expressing a constitutively active retinoic acid receptor in the lens exhibit ocular defects

Balkan, W., Klintworth, G. K., Bock, C. B., & Linney, E. A. (1992) · Developmental Biology · doi:10.1016/0012-1606(92)90200-z · Cited by 61 · see citing works

Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating-Factor)

Sherr, C. J., & Stanley, E. R. (1991) · Springer eBooks · doi:10.1007/978-1-4612-3210-0_15 · Cited by 58 · see citing works

Production and migration of monocytes and kinetics of macrophages

van Furth, R. (1992) · Springer eBooks · doi:10.1007/978-94-015-8070-0_1 · Cited by 56 · see citing works

Transcription of the human colony-stimulating factor-1 receptor gene is regulated by separate tissue-specific promoters

Roberts, W., Shapiro, L., Ashmun, R., et al. (1992) · Blood · doi:10.1182/blood.v79.3.586.bloodjournal793586 · Cited by 55 · see citing works

Isolation and characterization of the genes encoding mouse and human type-5 acid phosphatase

Cassady, A. I., KING, A. G., Cross, N. C. P., et al. (1993) · Gene · doi:10.1016/0378-1119(93)90420-8 · Cited by 53 · see citing works

Constitutive expression of the urokinase plasminogen activator gene in murine RAW264 macrophages involves distal and 5′ non-coding sequences that are conserved between mouse and pig

Cassady, A. I., Stacey, K. J., Nimmo, K. A., et al. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.24.6839 · Cited by 52 · see citing works

Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides.

Skorski, T., Szczylik, C., Ratajczak, M. Z., Malaguarnera, L., Gewirtz, A. M., & Calabretta, B. (1992) · The Journal of experimental medicine · doi:10.1084/jem.175.3.743 · Cited by 52 · see citing works

v-raf confers CSF-1 independent growth to a macrophage cell line and leads to immediate early gene expression without MAP-kinase activation.

Büscher, D., Sbarba, P. D., Hipskind, R. A., Rapp, U. R., Stanley, E. R., & Baccarini, M. (1993) · PubMed · Cited by 49 · see citing works

Induction of monocytic differentiation and tumorigenicity by v-Ha-ras in differentiation arrested hematopoietic cells

Hibi, S., Lohler, J., Friel, J., Stocking, C., & Ostertag, W. (1993) · Blood · doi:10.1182/blood.v81.7.1841.1841 · Cited by 44 · see citing works

Non-nuclear oncogenes and the regulation of gene expression in transformed cells.

Bortner, D. M., Langer, S. J., & Ostrowski, M. C. (1993) · PubMed · Cited by 43 · see citing works

The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor.Preprint

Bortner, D. M., Ulivi, M., Roussel, M. F., & Ostrowski, M. C. (1991) · Genes & Development · doi:10.1101/gad.5.10.1777 · Cited by 36 · see citing works

Components of the protein kinase C pathway induce Ia expression after injection into macrophages

Smith, M. R., Ramsburg, E. A., Kung, H. F., et al. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.149.4.1304 · Cited by 22 · see citing works

The ras Pathway: A Model for the Control of Proliferation in Animal Cells

Stacey, D. W. (1988) · Advances in experimental medicine and biology · doi:10.1007/978-1-4757-1980-2_11 · Cited by 5 · see citing works

CONSTITUTIVE EXPRESSION OF C-MYC IN NIH 3T3 CELLS WHICH COEXPRESS THE COLONY STIMULATING FACTOR-I RECEPTOR AND THE CATALYTIC DOMAIN OF THE GTPASE-ACTIVATING PROTEIN RESTORES COLONY STIMULATING FACTOR-I DEPENDENT MITOGENIC GROWTH

Bortner, D. M., Ulivi, M., & Ostrowski, M. C. (1992) · International Journal of Oncology · doi:10.3892/ijo.1.2.221 · Cited by 3 · see citing works

Transcription Factors, Normal Myeloid Development, and Leukemia

Tenen, D. G., Hromas, R., Licht, J. D., & Zhang, D.-E. (1997) · Blood · doi:10.1182/blood.v90.2.489 · Cited by 735 · see citing works

CCAAT Enhancer-Binding Protein (C/EBP) and AML1 (CBFα2) Synergistically Activate the Macrophage Colony-Stimulating Factor Receptor Promoter

Zhang, D.-E., Hetherington, C. J., Meyers, S., Rhoades, K. L., Larson, C. J., Chen, H.-M., Hiebert, S. W., & Tenen, D. G. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.3.1231 · Cited by 396 · see citing works

Ras-Mediated Phosphorylation of a Conserved Threonine Residue Enhances the Transactivation Activities of c-Ets1 and c-Ets2

Yang, B.-S., Hauser, C. A., Henkel, G., Colman, M. S., Beveren, C. V., Stacey, K. J., Hume, D. A., Maki, R. A., & Ostrowski, M. C. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.2.538 · Cited by 333 · see citing works

c-Jun Is a JNK-independent Coactivator of the PU.1 Transcription Factor

Behre, G., Whitmarsh, A. J., Coghlan, M. P., Hoang, T., Carpenter, C. L., Zhang, D.-E., Davis, R. J., & Tenen, D. G. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.8.4939 · Cited by 183 · see citing works

The JNK Are Important for Development and Survival of Macrophages

Himes, S. R., Sester, D. P., Ravasi, T., Cronau, S. L., Sasmono, T., & Hume, D. A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.4.2219 · Cited by 117 · see citing works

Early Changes in Behavior Deficits, Amyloid β-42 Deposits and MAPK Activation in Doubly Transgenic Mice Co-expressing NSE-Controlled Human Mutant PS2 and APPsw

Hwang, D. Y., Cho, J. S., Oh, J. H., Shim, S. B., Jee, S. W., Lee, S. H., Seo, S. J., Song, C. W., Lee, S. H., & Kim, Y. K. (2005) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-005-4950-x · Cited by 6 · see citing works

Transgenic mice: beyond the knockout

Miller, R. L. (2010) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00082.2010 · Cited by 25 · see citing works

[Transgenic mice in basic research].

Gassmann, M., Hennet, T., & Bauer, C. (1998) · PubMed · Cited by 1 · see citing works

Targeted Expression of the only Zinc Finger Gene in Transgenic Mice is Associated with Impaired Mammary Development

Besnard, N., Persuy, M., Stinnakre, M., et al. (2002) · Transgenic Research · doi:10.1023/a:1020347123109 · Cited by 2 · see citing works

In vivo expression of a conditional TGF-β1 transgene: no evidence for TGF-β1 transgene expression in SM22α-tTA transgenic mice

Lee, S., Agah, R., Xiao, M., et al. (2005) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2005.09.015 · Cited by 8 · see citing works