The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Human Scribble (Vartul) Is Targeted for Ubiquitin-Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin-Protein Ligase
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“Over 20 different PDZ domain-containing proteins have been identified as targets of the high-risk E6 proteins [271]; amongst them are discs of large tumour suppressor (hDlg) [268,269], scribble tumour suppressor (hScrib) [272] and Membrane-associated guanylate kinase inverted 1 (MAGI-1) [273,274]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [272]
In the citing paper
“hDlg, hScrib and MAGI-1 are tumour suppressors; the loss of these proteins facilitates cancer formation (reviewed in [275,276]), and all high-risk E6 proteins target them for proteasome-mediated degradation [272,277,278], most likely leading to the loss of cell polarity and facilitating tumour formation [279,280]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [272]
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Citations
Cites
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“E6 has been shown to induce telomerase activity (24), and a mutation in HPV type 16 (HPV16) E6 (SAT8–10) that renders it unable to target p53 leaves intact the ability to induce telomerase activity and to immortalize mammary epithelial cells (22).”
BackgroundLocalization of apical epithelial determinants by the basolateral PDZ protein Scribble
Bilder, D., & Perrimon, N. (2000) · Nature · doi:10.1038/35001108 · Cited by 716
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Cited by
Molecular biology of human papillomavirus infection and cervical cancer
Doorbar, J. (2006) · Clinical Science · doi:10.1042/cs20050369 · Cited by 1,072
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
Brumby, A. M., & Richardson, H. E. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg548 · Cited by 628
Narisawa‐Saito, M., & Kiyono, T. (2007) · Cancer Science · doi:10.1111/j.1349-7006.2007.00546.x · Cited by 528
Integrated activity of PDZ protein complexes regulates epithelial polarity
Bilder, D., Schober, M., & Perrimon, N. (2003) · Nature Cell Biology · doi:10.1038/ncb897 · Cited by 435
Zhan, L., Rosenberg, A., Bergami, K. C., Yu, M., Xuan, Z., Jaffe, A. B., Allred, C., & Muthuswamy, S. K. (2008) · Cell · doi:10.1016/j.cell.2008.09.045 · Cited by 436
Metadata
- Authors
- Nakagawa, S., & Huibregtse, J. M.
- Affiliations
- Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08855
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 2000-11-01
- Volume
- 20
- Issue
- 21
- Pages
- 8244-8253
- ISSN
- 1098-5549
- Cited by
- 382
- References
- 3
- Language
- en
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