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Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction

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Wnt-5a-CKIα Signaling Promotes β-Catenin/E-Cadherin Complex Formation and Intercellular Adhesion in Human Breast Epithelial Cells

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Casein kinase 1α–dependent feedback loop controls autophagy in RAS-driven cancers

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MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output

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FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

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MDMX contains an autoinhibitory sequence element

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Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

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Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding.

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A Critical Role for Noncoding 5S rRNA in Regulating Mdmx Stability

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Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges

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Phosphorylation of FADD by the kinase CK1α promotes KRAS ^G12D -induced lung cancer

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Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

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The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation

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Mutations in the phosphorylation sites of SARS-CoV-2 encoded nucleocapsid protein and structure model of sequestration by protein 14-3-3

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Inducible Priming Phosphorylation Promotes Ligand-independent Degradation of the IFNAR1 Chain of Type I Interferon Receptor

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Impaired CK1 Delta Activity Attenuates SV40-Induced Cellular Transformation In Vitro and Mouse Mammary Carcinogenesis In Vivo

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MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism

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Targeting Protein Kinases in Blood Cancer: Focusing on CK1α and CK2

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Casein kinase 1α inhibits p53 downstream of MDM2‑mediated autophagy and apoptosis in acute myeloid leukemia

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Mdm2 protein Expression is Strongly Associated with Survival in Malignant Pleural Mesothelioma

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Regulation of MDM4

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Casein Kinase 1 α Phosphorylates the Wnt Regulator Jade-1 and Modulates Its Activity

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The Potential of Targeting P53 and HSP90 Overcoming Acquired MAPKi-Resistant Melanoma

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Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex

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MDM2 oligomers: antagonizers of the guardian of the genome

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Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression

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MDMX in Cancer: A Partner of p53 and a p53-Independent Effector

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Mechanisms of action of immunomodulatory drugs — from teratogenicity to treatment of multiple myeloma

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MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling

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Tumor-derived CK1α mutations enhance MDMX inhibition of p53

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Mono‐Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity

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Induction of Huh‑7 cell apoptosis by HCV core proteins via CK1α‑p53‑Bid signaling pathway

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Phase I first-in-human dose escalation study of the oral casein kinase 1α and cyclin dependent kinase 7/9 inhibitor BTX A51 in advanced MDS and AML

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FPFT-2216, a Novel Anti-lymphoma Compound, Induces Simultaneous Degradation of IKZF1/3 and CK1α to Activate p53 and Inhibit NFκB Signaling

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Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self‐renewal

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Casein Kinase 1α—A Target for Prostate Cancer Therapy?

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Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation

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Decreased Expressions of CK1α and PTEN in Sinonasal Inverted Papilloma

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Murine double minute X plays a central role in leukemic transformation and may be a promising target for leukemia prevention strategies

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IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS

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Mice no longer immune to immunomodulatory drugs

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MDM4 (Murine Double Minute 4)

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Cellular carcinogenesis in preleukemic conditions:drivers and defenses

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Détermination des fonctions du gène E4F1 dans la voie p53 : caractérisation d’un nouveau niveau de régulation impliquant l’oncoprotéine Mdm2

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Targeting casein kinase 1α-mediated FADD phosphorylation restores sensitivity in select CDK4/6 inhibitor-resistant breast cancer models

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Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

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Casein Kinase 1 Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

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BPS2025 - Structure and dynamics of the p53-MDMX-CK1α complex

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MDMX 与 CK1α 对 p53 抑癌蛋白调节机制的研究进展

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