NF-κB RelA Phosphorylation Regulates RelA Acetylation

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Natural flavone tricin exerted anti-inflammatory activity in macrophage via NF-κB pathway and ameliorated acute colitis in mice

Li, X.-X., Chen, S.-G., Yue, G. G., Kwok, H.-F., Lee, J. K.-M., Zheng, T., Shaw, P., Simmonds, M. S. J., & Lau, C. B. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153625 · Cited by 55

BET Inhibition Attenuates Helicobacter pylori–Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation

Chen, J., Wang, Z., Hu, X., Chen, R., Romero–Gallo, J., Peek, R. M., & Chen, L. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502261 · Cited by 48

An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells

Yang, G., Song, Y., Wang, W., Han, Q., Ma, D., & Leung, C. (2021) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2021.105158 · Cited by 51

Novel Changes in NF-κB Activity during Progression and Regression Phases of Hyperplasia

Chandrakesan, P., Ahmed, I., Anwar, T., Wang, Y., Sarkar, S., Singh, P., Peleg, S., & Umar, S. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.129353 · Cited by 51

Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cells

Chen, Y., Chuang, T.-Y., Liu, C., Liu, C.-W., Lai, T.-C., Lai, T.-C., & Chen, Y. (2020) · Particle and Fibre Toxicology · doi:10.1186/s12989-020-00373-z · Cited by 52

Nonhistone targets of KAT2A and KAT2B implicated in cancer biology

Bondy‐Chorney, E., Denoncourt, A. M., Sai, Y., & Downey, M. (2018) · Biochemistry and Cell Biology · doi:10.1139/bcb-2017-0297 · Cited by 50

Arid5a Regulation and the Roles of Arid5a in the Inflammatory Response and Disease

Nyati, K. K., Agarwal, R. G., Sharma, P., & Kishimoto, T. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02790 · Cited by 49

SIRT1 counteracted the activation of STAT3 and NF-κB to repress the gastric cancer growth.

Lu, J., Zhang, L., Chen, X., Lu, Q., Yang, Y., Liu, J., & Ma, X. (2014) · PubMed Central · Cited by 49

Negative regulation of RelA phosphorylation: Emerging players and their roles in cancer

Lu, X., & Yarbrough, W. G. (2014) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2014.09.003 · Cited by 51

Redox Control of Protein–DNA Interactions: From Molecular Mechanisms to Significance in Signal Transduction, Gene Expression, and DNA Replication

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Canonical NF-κB Activation Is Essential for Epstein-Barr Virus Latent Membrane Protein 1 TES2/CTAR2 Gene Regulation

Gewurz, B. E., Mar, J. C., Padi, M., Zhao, B., Shinners, N. P., Takasaki, K., Bedoya, E., Zou, J., Cahir-McFarland, E. D., Quackenbush, J. F., et al. (2011) · Journal of Virology · doi:10.1128/jvi.00422-11 · Cited by 47

Suppression of the SAP18/HDAC1 complex by targeting TRIM56 and Nanog is essential for oncogenic viral FLICE-inhibitory protein-induced acetylation of p65/RelA, NF-κB activation, and promotion of cell invasion and angiogenesis

Ding, X., Xu, J., Wang, C., Feng, Q., Wang, Q., Yang, Y., Lü, H., Wang, F., Zhu, K., Li, W., et al. (2019) · Cell Death and Differentiation · doi:10.1038/s41418-018-0268-3 · Cited by 48

PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis

Paul, A., Gunewardena, S., Stecklein, S., Saha, B., Parelkar, N. K., Danley, M., Rajendran, G., Home, P., Ray, S., Jokar, I., et al. (2014) · Cell Death and Differentiation · doi:10.1038/cdd.2014.62 · Cited by 51

Control of the Autophagy Pathway in Osteoarthritis: Key Regulators, Therapeutic Targets and Therapeutic Strategies

Valenti, M. T., Carbonare, L. D., Zipeto, D., & Mottes, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052700 · Cited by 47

The Effects of Hematopoietic Growth Factors on Neurite Outgrowth

Su, Y., Cui, L., Piao, C.-S., Li, B., & Zhao, L.-R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075562 · Cited by 46

Copine-I represses NF-κB transcription by endoproteolysis of p65

Ramsey, C. S., Yeung, F., Stoddard, P. B., Li, D., Creutz, C. E., & Mayo, M. W. (2008) · Oncogene · doi:10.1038/sj.onc.1211030 · Cited by 46

Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of IκB kinases in mice: impact on histone acetylation

Chung, S., Sundar, I. K., Yao, H., Ho, Y.-S., & Rahman, I. (2010) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00426.2009 · Cited by 47

Quantification of Activated NF-κB/RelA Complexes Using ssDNA Aptamer Affinity – Stable Isotope Dilution—Selected Reaction Monitoring—Mass Spectrometry

Zhao, Y., Widen, S. G., Jamaluddin, M., Tian, B., Wood, T. G., Edeh, C. B., & Brasier, A. R. (2011) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m111.008771 · Cited by 46

Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression

Cleophas, M. C. P., Crișan, T. O., Klück, V., Hoogerbrugge, N., Netea-Maier, R. T., Dinarello, C. A., Netea, M. G., & Joosten, L. A. B. (2019) · Arthritis Research & Therapy · doi:10.1186/s13075-019-1834-x · Cited by 46

Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game

van der Sanden, S. M. G., Wu, W., Dybdahl-Sissoko, N., Weldon, W. C., Brooks, P., O’Donnell, J., Jones, L. P., Brown, C. J., Tompkins, S. M., Oberste, M. S., et al. (2015) · Journal of Virology · doi:10.1128/jvi.01464-15 · Cited by 45

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB

Chen, L., Mu, Y., & Greene, W. C. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf660 · Cited by 827

NF-kappaB RelA phosphorylation regulates RelA acetylation

Chen, L.-F., Williams, S. A., Mu, Y., Duerr, J. M., Buckbinder, L., Greene, C., Acetylation, R., Chen, L.-F., Williams, S. A., Mu, Y., et al. (2013)

Phosphorylation, acetylation and methylation modification and the biological activity regulation of nuclear transcription factor NF-κB/RelA

Wang, L. (2012)

Functional Interplay between Acetylation and Methylation of the RelA Subunit of NF-κB

Yang, X., Tajkhorshid, E., & Chen, L. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01343-09 · Cited by 149

Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65

Buerki, C., Rothgiesser, K., Valovka, T., Owen, H. R., Rehrauer, H., Fey, M., Lane, W. S., & Hottiger, M. O. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn003 · Cited by 116