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Cited by 75Viral gastroenteritis research and epidemiologyBacteriophages and microbial interactionsAnimal Virus Infections Studies

Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses

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Yinda, Claude Kwe, Vanhulle, Emiel, Conceição-Neto, Nádia, Beller, Leen, Deboutte, Ward, Shi, Chenyan, Ghogomu, Stephen Mbigha, Maes, Piet +2 more·2019·mSphere
DOI 10.1128/msphere.00585-18PMC PMC6344602
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Abstract

Despite the availability of diagnostic tools for different enteric viral pathogens, a large fraction of human cases of gastroenteritis remains unexplained. This could be due to pathogens not tested for or novel divergent viruses of potential animal origin. Fecal virome analyses of Cameroonians showed a very diverse group of viruses, some of which are genetically related to those identified in animals. This is the first attempt to describe the gut virome of humans from Cameroon. Therefore, the data represent a baseline for future studies on enteric viral pathogens in this area and contribute to our knowledge of the world’s virome. The studies also highlight the fact that more viruses may be associated with diarrhea than the typical known ones. Hence, it provides meaningful epidemiological information on diarrhea-related viruses in this area.

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  • The picobirnavirus-related transcript found here is similar to picobirnaviruses described as potentially zoonotic in humans with gastroenteritis.

    “It is also similar to picobirnaviruses described as potentially zoonotic in humans with gastroenteritis (Yinda et al. 2019).”

    From Red fox viromes in urban and rural landscapes (2020) · cites this paper as Yinda et al. 2019

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Sorted by citations

Authors
Yinda, C. K., Vanhulle, E., Conceição-Neto, N., Beller, L., Deboutte, W., Shi, C., Ghogomu, S. M., Maes, P., Van Ranst, M., & Matthijnssens, J.
Affiliations
  • Rega Institute for Medical Research (BE)
  • Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Viral Metagenomics, KU Leuven-University of Leuven, Leuven, Belgium
  • University of Buea (CM)
  • Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven-University of Leuven, Leuven, Belgium
Corresponding author
Matthijnssens, Jelle
ORCID
Venue
mSphere
Publisher
American Society for Microbiology
Published
2019-02-27
Volume
4
Issue
1
ISSN
2379-5042 (ISSN-L)
DOI
10.1128/msphere.00585-18
PMC
PMC6344602
OpenAlex
W2911301213
Cited by
75
References
6
Citations by year
2026: 6 · 2025: 5 · 2024: 10 · 2023: 6 · 2022: 10 · 2021: 18 · 2020: 17 · 2019: 3
FWCI
9.20
Type
journal article
Language
en
Open access
Licence
Locations
  • mSphere (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Lirias (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
KU Leuven (EJX-C9928-StG/15/020BF)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
  • Physical Sciences › Environmental Science › Ecology › Bacteriophages and microbial interactions
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
Keywords
gut virome, enteric viruses, interspecies transmission, viral diversity, diarrhea, Cameroon, viral epidemiology
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Animals, Cameroon, Child, Child, Preschool, Diarrhea, Feces, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Phylogeny, Virus Diseases, Viruses, Zoonoses, Prevalence, Disease Transmission, Infectious, Young Adult, Metagenomics

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