‘Too much, too late’: mixed methods multi-channel video recording study of computerized decision support systems and GP prescribing
Open accessAbstract
OBJECTIVE: Computerized decision support systems (CDSS) are commonly deployed to support prescribing, although over-riding of alerts by prescribers remains a concern. We aimed to understand how general practitioners (GPs) interact with prescribing CDSS in order to inform deliberation on how better to support prescribing decisions in primary care. MATERIALS AND METHODS: Quantitative and qualitative analysis of interactions between GPs, patients, and computer systems using multi-channel video recordings of 112 primary care consultations with eight GPs in three UK practices. RESULTS: 132 prescriptions were issued in the course of 73 of the consultations, of which 81 (61%) attracted at least one alert. Of the total of 117 alerts, only three resulted in the GP checking, but not altering, the prescription. CDSS provided information and safety alerts at the point of generating a prescription. This was 'too much, too late' as the majority of the 'work' of prescribing occurred prior to using the computer. By the time an alert appeared, the GP had formulated the problem(s), potentially spent several minutes considering, explaining, negotiating, and reaching agreement with the patient about the proposed treatment, and had possibly given instructions and printed an information leaflet. DISCUSSION: CDSS alerts do not coincide with the prescribing workflow throughout the whole GP consultation. Current systems interrupt to correct decisions that have already been taken, rather than assisting formulation of the management plan. CONCLUSIONS: CDSS are likely to be more acceptable and effective if the prescribing support is provided much earlier in the process of generating a prescription.
AI snapshot
Written from the paper’s full text.
TL;DR
In UK primary care, computerized decision support alerts usually appeared after GPs had already formulated, negotiated, and agreed a prescribing decision, so they were rarely acted on. The authors argue CDSS should support prescribing much earlier in the consultation workflow rather than interrupting at the point of generating a prescription.
Key findings
- Of 132 prescriptions issued across 73 of 112 recorded consultations, 81 (61%) attracted at least one alert; there were 117 alerts in total (55 safety alerts, 57 process warnings, 5 add-ins), and only 3 (2%) resulted in the GP checking—but not altering—the prescription.
- Among 62 new acute prescriptions in 49 consultations, therapeutic talk accounted for 40% of all GP utterances, with 53% occurring before the computer was used to process the prescription and 72% before the prescription was printed; patient therapeutic talk was 16% of conversation, with 79% before printing.
- Qualitative analysis identified four prescribing tasks—formulating the problem, negotiating a proposed medication, reaching agreement, and instructing the patient—that generally occurred before computer prescribing, making alerts “too much, too late.”
Methods
- Mixed methods multi-channel video recording of 112 primary care consultations with 8 GPs in 3 UK practices using EMIS or INPS Vision; whole clinics were recorded during two site visits approximately 6 months apart.
- Quantitative analysis used OBSWIN to time computer tasks, Roter Interaction Analysis System coding for therapeutic talk, and independent classification of alerts and GP responses; qualitative analysis coded verbatim transcripts of consultations containing new acute prescriptions.
- Detailed analysis focused on 62 new acute prescriptions from 49 consultations.
Limitations
- Stated by the paper: the eight participating GPs may not be representative; willingness to be videoed may reflect confidence in consulting and computer use; the study may not capture the full range of prescribing scenarios; and the study was UK-based, although alert fatigue is an international concern.
- Evident from the text: the sample is small and limited to three practices and two clinical software systems, and the observational video method could affect consultation behavior, although the authors cite evidence that recording does not significantly alter the consultation process.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
0 of 23 cited sources checked · 0 supported · 0 flagged
- Findingown data
The CDSS delivered information and safety alerts at the moment a prescription was being generated.
“CDSS provided information and safety alerts at the point of generating a prescription.”
Quote in the paperSubstantial claim - Findingown data
Most of the work involved in prescribing took place before the GP used the computer.
“This was 'too much, too late' as the majority of the 'work' of prescribing occurred prior to using the computer.”
Quote in the paperSubstantial claim - Findingown data
New acute copied prescriptions had 11 interruptions (69%).
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Quote in the paperSubstantial claim - Findingown data
Background information about known allergies, interactions, or adverse events was presented for every new prescription.
“In addition, background information about the presence/absence of known allergies, interactions, or adverse events was presented for all new prescriptions.”
Quote in the paperNot a substantial claim - Findingown data
Re-authorize repeat prescriptions had 4 interruptions (14%).
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Quote in the paperNot a substantial claim
- Findingown data
Over half of the therapeutic talk by doctors and patients occurred before the computer was used to generate the prescription.
“Analysis of RIAS-coded utterances (table 5) revealed that over half the therapeutic talk by doctor and patient occurred before the computer was used to generate the prescription.”
Quote in the paperSubstantial claim - Findingown data
GPs made prescribing decisions, often in negotiation with the patient, long before they turned to the computer to generate the paper prescription.
“Decisions about prescribing were made by the GPs, often in negotiation with the patient, long before the GP turned to the computer to generate the paper prescription.”
Quote in the paperSubstantial claim - Findingown data
There were 55 safety alerts.
“| Safety alerts | 35 | 13 | 3 | 4 | 0 | 55 |”
Quote in the paperSubstantial claim - Findingown data
In primary care, presenting alerts at the point of selecting drugs is already too late.
“however, our data from a primary care setting suggest that this is already too late.”
Quote in the paperSubstantial claim - Findingown data
New acute prescriptions had 31 interruptions (50%).
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Quote in the paperSubstantial claim - Findingreasoning
Current CDSS interrupt to correct decisions already made rather than to assist earlier deliberations.
“Current systems interrupt to correct decisions already made rather than to assist earlier deliberations.”
Quote in the paperSubstantial claim - Findingown data
The study observed 112 GP consultations from eight GPs in three practices.
“We observed a total of 112 GP consultations from the clinics of eight GPs in three practices (identified by pseudonym in this report) (table 2).”
Quote in the paperSubstantial claim - Findingown data
49 prescriptions were interrupted by an alert or warning.
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Quote in the paperSubstantial claim - Findingown data
Safety alerts about patient-specific allergies, drug interactions, and contra-indications interrupted the clinician's workflow either when the drug was selected (in EMIS) or just before the prescription was sent to print (in EMIS and Vision).
“Safety alerts relating to patientspecific allergies and drug interactions, and general information about contra-indications interrupted the clinician's workflow (ie, requiring a response) either at the point of selecting the drug (in EMIS) or just before sending the prescription to print (EMIS and Vision).”
Quote in the paperSubstantial claim - Findingown data
There were 57 process warnings.
“| Process warnings | 15 | 4 | 8 | 25 | 5 | 57 |”
Quote in the paperNot a substantial claim - Findingown data
In both Vision and EMIS, background information on allergies and adverse reactions appeared as soon as the prescribing dialogue box was opened.
“In both Vision and EMIS, background information on allergies and adverse reactions was presented as soon as the prescribing dialogue box was activated.”
Quote in the paperNot a substantial claim - Findingnone given
Acute prescriptions are not uncommonly copied from previous episodes.
“Acute prescriptions are not uncommonly copied from previous episodes”
Quote in the paperNot a substantial claim - Findingown data
There were 117 total interruptions.
“| Total interruptions | 53 | 17 | 13 | 29 | 5 | 117 |”
Quote in the paperNot a substantial claim - Findingown data
Add-ins such as ScriptSwitch interrupted Vision users at one site with additional alerts.
“Add-ins such as 'ScriptSwitch' interrupted Vision users on one site with further alerts.”
Quote in the paperNot a substantial claim - Findingreasoning
CDSS alerts do not integrate with the flow of prescribing work within the consultation.
“CDSS alerts do not integrate with the flow of prescribing work within the consultation.”
Quote in the paperSubstantial claim - Findingnone given
Once a clinician has opened the prescribing dialogue box, access to other EHR pages containing crucial information such as the latest renal function may not be possible.
“Currently, once a clinician has opened the prescribing dialogue box, access to other pages in the EHR containing crucial information (such as latest renal function) may not be possible.”
Quote in the paperSubstantial claim - Findingown data
New repeat prescriptions had 3 interruptions (21%).
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Quote in the paperNot a substantial claim - Findingown data
Entering a diagnosis before processing a prescription, as required by the EMIS software, was perceived as annoying.
“Entering a diagnosis before processing a prescription, as required by the EMIS software, was perceived as 'annoying,'”
Quote in the paperNot a substantial claim - Findingown data
Issue existing repeat prescriptions had 0 interruptions.
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Quote in the paperNot a substantial claim - Findingown data
Process alerts, such as warnings about prescribing frequency or duplicated prescriptions, also required a response and pre-empted printing, especially in Vision.
“Process alerts (eg, warnings about prescribing frequency, duplicated prescriptions) also requiring a response from the GP, pre-empted printing especially in Vision.”
Quote in the paperNot a substantial claim - Premisecitation
The overall effectiveness of CDSS in clinical practice is unclear.
“overall effectiveness in clinical practice is unclear.14”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [14] Black, 2011, The impact of eHealth on the quality and safety of health care: a systematic overview, PLoS Med source
Not checked in the free run.
- Interpretationreasoning
Existing systems interrupt to correct decisions that have already been made, instead of helping to formulate the management plan.
“Current systems interrupt to correct decisions that have already been taken, rather than assisting formulation of the management plan.”
Quote in the paperSubstantial claim- Rests on an assumption: The findings from the eight GPs in three UK practices are representative of GP prescribing with CDSS in primary care more generally.
- Interpretationreasoning
CDSS are likely to be more acceptable and effective if prescribing support is offered much earlier in the process of generating a prescription.
“CDSS are likely to be more acceptable and effective if the prescribing support is provided much earlier in the process of generating a prescription.”
Quote in the paperSubstantial claim- Rests on an assumption: The findings from the eight GPs in three UK practices are representative of GP prescribing with CDSS in primary care more generally.
- Interpretationreasoning
CDSS alerts do not align with the prescribing workflow across the whole GP consultation.
“CDSS alerts do not coincide with the prescribing workflow throughout the whole GP consultation.”
Quote in the paperSubstantial claim- Rests on an assumption: The findings from the eight GPs in three UK practices are representative of GP prescribing with CDSS in primary care more generally.
- Premisecitation
Evidence indicates that awareness of being video recorded does not significantly alter the consultation process.
“Although both patient and GP were aware of the recording, there is evidence that this does not significantly affect the process of the consultation, 47 48”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [47] Pringle, 1990, Does awareness of being video recorded affect doctors' consultation behaviour, Br J Gen Pract
Not checked in the free run.
- cites [48] Coleman, 2000, Using video-recorded consultations for research in primary care: advantages and limitations, Fam Pract source
Not checked in the free run.
- Study design and conductnone given
The eight participating GPs may not represent the full range of professionals.
“The eight participating GPs may not be representative of the range of professionals, although we recruited clinicians with diverse personal and practice demographics.”
Quote in the paperNot a substantial claim - Study design and conductown data
Using multi-channel video recording allowed the team to gain an in-depth understanding of the prescribing process by combining conversation, patient, professional actions, and computer use within the consultation.
“Our use of MCV recording enabled an in-depth understanding of the process of prescribing as we were able to integrate the conversation, patient, professional actions, and computer use within the consultation.”
Quote in the paperSubstantial claim - Interpretationreasoning
Balancing tacit and explicit modes of knowledge underpins safe prescribing.
“Balancing these two modes of knowledge underpins safe prescribing”
Quote in the paperSubstantial claim - Premisecitation
Excessive alerts, especially when procedural and cost information are added to safety alerts, may be counterproductive because they cause user fatigue.
“excessive alerts, exacerbated in contemporary practice when procedural information and cost advice are provided in addition to safety alerts, may be counterproductive as they lead to user fatigue.12 20”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [12] Kuperman, 2007, Medication-related clinical decision support in computerized provider order entry systems: a review, J Am Med Inform Assoc source
Not checked in the free run.
- cites [20] van der Sijs, 2006, Overriding of drug safety alerts in computerized physician order entry, J Am Med Inform Assoc source
Not checked in the free run.
- Study design and conductreasoning
The study may not have captured the full range of prescribing scenarios.
“We may not have captured the full range of prescribing scenarios, although by recording whole clinics we hoped to capture a typical profile of primary care consultations.”
Quote in the paperNot a substantial claim - Premisecitation
A recent systematic review found few studies that showed substantial improvements in prescribing behaviour.
“a recent systematic review found few studies showing substantial improvements in prescribing behavior.17”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [17] Schedlbauer, 2009, What evidence supports the use of computerized alerts and prompts to improve clinicians' prescribing behavior?, J Am Med Inform Assoc source
Not checked in the free run.
- May combine two claims. 20
- Classified as probably not a substantial claim. 19
May combine two claims.
Findingown dataWhen an alert appeared, the GP had already formulated the problem, and may have spent time considering, explaining, negotiating, and agreeing the treatment with the patient, and possibly given instructions and printed an information leaflet.
“By the time an alert appeared, the GP had formulated the problem(s), potentially spent several minutes considering, explaining, negotiating, and reaching agreement with the patient about the proposed treatment, and had possibly given instructions and printed an information leaflet.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataOf the 117 alerts recorded, only three (2%) led the GP to check prescribing information, and in none of these cases did the GP change the prescription.
“Only three (2%) of the alerts resulted in apparent action on the part of the GP: in each case the GP checked the prescribing information (in a formulary or computer database) but did not subsequently alter the prescription.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn the study, 132 prescriptions were issued during 73 of the 112 consultations, and 81 of those prescriptions (61%) triggered at least one alert.
“Overall, 132 prescriptions were issued in the course of 73 of the consultations, of which 81 (61%) attracted at least one alert.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFour tasks were identified as forming the work of prescribing: formulating the problem so a prescription was justified, negotiating a proposed medication, reaching agreement on treatment, and instructing the patient on using the medication.
“we identified four tasks which formed the 'work' of prescribing: (i) formulating the problem such that a prescription was justified; (ii) negotiating a proposed medication; (iii) reaching agreement on the treatment; and (iv) instructing the patient on using the medication.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Findingown dataThe subsequent analysis focused on 62 new acute prescriptions from 49 consultations.
“Our subsequent analysis focuses on the 62 new acute prescriptions observed in the course of 49 consultations.”
Quote in the paperSubstantial claimMay combine two claims.
FindingreasoningBy the time an alert appears, the GP has already formulated the problem, may have spent several minutes considering, explaining, negotiating and reaching agreement with the patient, possibly given instructions, and printed an information leaflet about the proposed treatment.
“By the time an alert appears the GP will have formulated a problem, potentially spent several minutes considering, explaining, negotiating, and reaching agreement with the patient, possibly given instructions, and printed an information leaflet about the proposed treatment.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataOf the 117 alerts, 55 were safety alerts, 57 were process warnings, and five were generated by ScriptSwitch.
“Of the total of 117 alerts, 55 were safety alerts and 57 were process warnings, with an further five generated by 'ScriptSwitch' (an additional system funded by the local healthcare trust to advise on cost-effective prescribing) in one of the practices.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThere were 5 add-ins.
“| Add-ins | 3 | 0 | 2 | 0 | 0 | 5 |”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataMultiple alerts occurred in 29 prescriptions (22%), and five prescriptions were interrupted by three or more alerts.
“Multiple alerts occurred in 29 (22%) prescriptions, with five interrupted by three or more alerts”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataTherapeutic talk made up 16% of the patient's conversation, and 79% of it occurred before the prescription was printed.
“Similarly, therapeutic talk contributed 16% of the patient's conversation, with 79% occurring before the prescription was printed.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThree GPs in one practice used INPS Vision software, and five GPs in two practices used EMIS.
“Three GPs in one practice (Seaside) used INPS Vision software and five GPs in two practices (Church and Hills) used EMIS”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Findingnone givenExploring previous episodes is often part of history taking.
“exploration of which is often part of history taking.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataTherapeutic talk made up 40% of all GP utterances in consultations that resulted in a new acute prescription; 53% of this talk occurred before the computer was used to process the prescription, and 72% occurred before the prescription was printed.
“Therapeutic talk accounted for 40% of all GP utterances in consultations resulting in a new acute prescription, 53% of which occurred before the computer was used to process the prescription and 72% before the prescription was printed.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThese four tasks were present, implicitly or explicitly, in every consultation involving a new acute prescription, though they varied in duration, order, and could be interspersed with other tasks.
“These tasks were present (implicitly or explicitly) in all the consultations involving a new acute prescription, although they varied in the time they took, did not occur in any particular order, and could be interspersed with other tasks within the consultation.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe study recorded 132 prescriptions.
“| Number of prescriptions | 62 | 16 | 14 | 28 | 12 | 132 |”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningThe CDSS alerts were too much and came too late in the prescribing process.
“This was 'too much, too late' as the majority of the 'work' of prescribing occurred prior to using the computer.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationAlerts that give the prescriber a choice and require a reason for deviating from protocol may be more effective than alerts that can simply be over-ridden.
“Alerts that offer the prescriber choice, and require reasons for deviation from protocol may be more effective than those that can simply be over-ridden.20 26”
Quote in the paperNot a substantial claim0 of 2 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe challenge of implementing effective decision support for prescribing, and specifically alert fatigue, is international.
“Our study was UK-based, although the challenge of implementing effective decision support for prescribing, and specifically the problem of alert fatigue, is international.12 24 50”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [12] Kuperman, 2007, Medication-related clinical decision support in computerized provider order entry systems: a review, J Am Med Inform Assoc source
Not checked in the free run.
- cites [24] Phansalkar, 2010, A review of human factors principles for the design and implementation of medication safety alerts in clinical information systems, J Am Med Inform Assoc source
Not checked in the free run.
- cites [50] Ludwick, 2009, Adopting electronic medical records in primary care: Lessons learned from health information systems implementation experience in seven countries, Int J Med Inform source
Not checked in the free run.
May combine two claims.
PremisecitationCDSS is used universally in UK primary care and now includes warnings about real and potential adverse drug effects.
“CDSS is universal in UK primary care and has broadened to include warnings of real and potential adverse drug effects.5 8”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [5] Duerden, 2011
Not checked in the free run.
- cites [8] Kaushal, 2003, Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review, Arch Intern Med source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
Study design and conductnone givenAll consultations were transcribed verbatim, and transcripts containing new acute prescriptions were examined for all prescribing-related conversation.
“All consultations were transcribed verbatim and transcripts of consultations which included one or more new acute prescriptions were examined for all conversation relating to prescribing.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Study design and conductnone givenThe GPs' willingness to be videoed may reflect relatively high confidence in their consulting skills and computer use.
“Their willingness to be videoed may reflect relative confidence in their consulting skills and computer use, although the particular task of interest (computer prescribing) is routine within primary care.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Interpretationown dataThe study's data, from observation of real-life consultations, can help designers and users understand how to align CDSS functionality with the GP perspective on prescribing work.
“Our data, from observation of real-life consultations, can help designers and users understand how to align CDSS functionality with the GP perspective on the work of prescribing.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationProblems such as inaccurate allergy coding, spurious alerts that frustrate users and prompt inappropriate clinical responses, and workarounds that bypass safety features have been identified.
“inaccurate coding of allergies, 9 spurious alerts incurring user frustration and inappropriate clinical responses, 10 19 and workarounds which bypass intrinsic safety features 15 have been identified.”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [9] Kaelber, 2007, Health information exchange and patient safety, J Biomed Inform source
Not checked in the free run.
- cites [10] Karnon, 2007, A prospective hazard and improvement analytic approach to predicting the effectiveness of medication error interventions, Saf Sci source
Not checked in the free run.
- cites [19] Cresswell, 2008, Information technology-based approaches to reducing repeat drug exposure in patients with known drug allergies, J Allergy Clin Immunol source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataAll prescribing-related dialogue was coded using a framework developed inductively by two researchers.
“All dialogue related to prescribing was coded into a framework developed inductively by JH and HP (see online supplementary table S2).”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningAn alert appearing in the final seconds of generating the paper prescription is likely to be seen as intrusive and unwelcome, and raises the chance that it will be ignored.
“An alert in the final seconds of the task of generating the paper prescription is likely to be regarded as intrusive and unwelcome, and increases the probability of it being ignored.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductcitationThe paper provided descriptions of practices, clinicians, computer systems, patients, and the prescribing process using the two computer systems to allow assessment of transferability to other healthcare contexts.
“To enable assessment of transferability to other healthcare contexts, 49 we have provided a description of the practices, clinicians, and computer systems (table 2) and characteristics of the patients (table 4) and the process of prescribing using the two computer systems (table 6).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [49] Murphy, 1998
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationEstablished methodology was used for multi-channel video recordings of consultations.
“We used established methodology to undertake multi-channel video (MCV) recordings of consultations.[42][43][44]”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [42] Pinnock H Cresswell K Fernado B . Evaluation of the effect of IT on interactions between healthcare workers and patients (NHS CFHEP 010) Connecting for Health Evaluation Programme. 2011. http://www.birmingham.ac.uk/research/activity/mds/projects/HaPS/PHEB/CFHEP/reports/projects/010.aspx (accessed Sep 2012).
Not checked in the free run.
- cites [43] de Lusignan, 2008, The ALFA (Activity Log Files Aggregation) toolkit: a method for precise observation of the consultation, J Med Internet Res source
Not checked in the free run.
- cites [44] de Lusignan, 2011, Reporting observational studies of the use of information technology in the clinical consultation. A position statement from the IMIA Primary Health Care Informatics Working Group (IMIA PCI WG), . Yearb Med Inform
Not checked in the free run.
Classified as probably not a substantial claim.
PremisecitationSecondary care studies have suggested that alerts should be presented at the point of selecting drugs rather than at the moment of printing.
“Studies undertaken in a secondary care setting have suggested the importance of presenting alerts at the point of selecting drugs (as opposed to the moment of printing), 22”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [22] Miller, 2005, The anatomy of decision support during inpatient care provider order entry (CPOE): Empirical observations from a decade of CPOE experience at Vanderbilt, J Biomed Inform source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenEmerging themes were discussed with the multidisciplinary team.
“Emerging themes were discussed with the multidisciplinary team.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductcitationThe Roter Interaction Analysis System (RIAS) is a validated and widely used tool that codes verbal utterances into mutually exclusive categories.
“The validated Roter Interaction Analysis System (RIAS) 45 is a widely used tool which codes the verbal 'utterances' of both the patient and clinician into 41 mutually exclusive categories”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [45] Pflug, 2010, Measuring the impact of the computer on the consultation: an open source application to combine multiple observational outputs, Inform Health Soc Care source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe use of discrete cameras made the recording process as unobtrusive as possible.
“our use of discrete cameras ensured that the process was as unobtrusive as possible”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationThe work of prescribing is tacit, while processing the prescription involves explicit, codified rules and procedures.
“The work of prescribing is tacit, while that required for processing the prescription involves explicit, codified rules and procedures.52”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [52] Wyatt, 2001, Management of explicit and tacit knowledge, J R Soc Med source
Not checked in the free run.
Classified as probably not a substantial claim.
Study design and conductown dataTwo researchers independently observed the number and type of alerts and the associated dialogue boxes for each prescription.
“Two researchers ( JH and HP) independently observed the number, type of alert (see table 1 for definitions) and associated dialogue boxes presented by the system in connection with each prescription.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenGP practices were purposively sampled to ensure a spread of demography, size, and clinical software.
“We purposively sampled GP practices to ensure a spread of demography, size, and clinical software, and invited up to three GPs in each practice to participate.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductown dataThe mixed-method analysis allowed the study both to quantify the issue and to use qualitative analysis to understand the prescribing process that CDSS aims to influence.
“Our mixed method analysis enabled us both to quantify the issue and to use qualitative analysis to understand the process of prescribing which the CDSS seeks to influence.”
Quote in the paperSubstantial claim
The paper relies on this without support.
The findings from the eight GPs in three UK practices are representative of GP prescribing with CDSS in primary care more generally.
“We observed a total of 112 GP consultations from the clinics of eight GPs in three practices (identified by pseudonym in this report) (table 2).”
The paper relies on this without support.
When a GP over-rode an alert with no apparent attention, this indicates that the GP did not attend to the alert.
“We classified the clinician as having responded to an alert (if they took action such as selecting an alternative drug, changing a dose, checking with the patient, or seeking information from a formulary) or dismissed an alert (if they over-rode it with no apparent attention).”
The paper relies on this without support.
Computer prescribing is routine within primary care.
“although the particular task of interest (computer prescribing) is routine within primary care.”
The paper relies on this without support.
CDSS has become the norm for GP prescribing in the UK and many other countries.
“CDSS has become the norm for GP prescribing in the UK and many other countries but is concentrated in the form of information and safety alerts issued at the point of prescribing.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Alerts appear 'too late', when the prescribing decision has been made and negotiated with the patient, and consequently do not fit correctly into the workflow and are likely to be ignored by providers.
“As Hayward et al. describe, alerts appear”
From Drug interaction alert override rates in the Meaningful Use era: No evidence of progress (2014) · cites this paper as [24]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Conflicting counts of prescriptions with alerts
MajorThe results say 81 of 132 prescriptions attracted an alert, but Table 3 reports 49 prescriptions interrupted by an alert or warning. The table distinguishes background information from alerts, so its count does not support the reported 81.
“Overall, 132 prescriptions were issued in the course of 73 of the consultations, of which 81 (61%) attracted at least one alert.”
“| Number of prescriptions interrupted by an alert or warning, n | 31 (50) | 11 (69) | 3 (21) | 4 (14) | 0 | 49 |”
Patient age-band counts total 46, not 47
MinorThe seven age-band counts in Table 4 sum to 46, one fewer than the stated 47 patients.
Reported 47 · recomputed 46
“| Parameter | Characteristic | n=47 | | --- | --- | --- | | Sex | Male | 12 | | | Female | 35 | | Age bands (years) | 0-4 | 2 | | | 5-15 | 0 | | | 16-24 | 4 | | | 25-44 | 4 | | | 45-64 | 19 | | | 65-74 | 7 | | | 75+ | 10 |”
Percentage of alerts prompting action is rounded incorrectly
MinorThree of 117 alerts is 2.56%, which rounds to 3% rather than the reported 2% at whole-percent precision.
Reported 2 · recomputed 2.564103
“Only three (2%) of the alerts resulted in apparent action on the part of the GP”
Cites
Crossing the Quality Chasm: A New Health System for the 21st Century
Baker, A. (2001) · BMJ · doi:10.1136/bmj.323.7322.1192 · Cited by 10,754 · see citing works
Crossing the Quality Chasm: A New Health System for the 21st Century
Committee on Quality of Health Care in America (2002) · Journal for Healthcare Quality · doi:10.1111/j.1945-1474.2002.tb00463.x · Cited by 8,508 · see citing works
Garg, A. X., Adhikari, N. K. J., McDonald, H., Rosas-Arellano, M. P., Devereaux, P. J., Beyene, J., Sam, J., & Haynes, R. B. (2005) · JAMA · doi:10.1001/jama.293.10.1223 · Cited by 2,936 · see citing works
Kawamoto, K., Houlihan, C. A., Balas, E. A., & Lobach, D. F. (2005) · BMJ · doi:10.1136/bmj.38398.500764.8f · Cited by 2,703 · see citing works
Role of Computerized Physician Order Entry Systems in Facilitating Medication Errors
Koppel, R. (2005) · JAMA · doi:10.1001/jama.293.10.1197 · Cited by 2,126 · see citing works
The Impact of eHealth on the Quality and Safety of Health Care: A Systematic Overview
Black, A. D., Car, J., Pagliari, C., Anandan, C., Cresswell, K., Bokun, T., McKinstry, B., Procter, R., Majeed, A., & Sheikh, A. (2011) · PLoS Medicine · doi:10.1371/journal.pmed.1000387 · Cited by 1,442 · see citing works
Self-citationBates, D. W., Kuperman, G. J., Wang, S., Gandhi, T., Kittler, A., Volk, L., Spurr, C., Khorasani, R., Tanasijevic, M., & Middleton, B. (2003) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m1370 · Cited by 1,346 · see citing works
Overriding of Drug Safety Alerts in Computerized Physician Order Entry
van der Sijs, H., Aarts, J., Vulto, A., & Berg, M. (2006) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m1809 · Cited by 1,117 · see citing works
Qualitative research methods in health technology assessment: a review of the literature.
Murphy, Dingwall, Greatbatch, Parker, & Watson (1998) · Health Technology Assessment · doi:10.3310/hta2160 · Cited by 1,107 · see citing works
ROTER, D. L., & Larson, S. (2002) · Patient Education and Counseling · doi:10.1016/s0738-3991(02)00012-5 · Cited by 913 · see citing works
Medication-related clinical decision support in computerized provider order entry systems: a review
Kuperman, G. J., Bobb, A., Payne, T. H., Avery, A. J., Gandhi, T. K., Burns, G., Classen, D. C., & Bates, D. W. (2007) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m2170 · Cited by 763 · see citing works
LUDWICK, D., & DOUCETTE, J. (2009) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2008.06.005 · Cited by 668 · see citing works
Grand challenges in clinical decision support
Sittig, D. F., Wright, A., Osheroff, J. A., Middleton, B., Teich, J. M., Ash, J. S., Campbell, E., & Bates, D. W. (2008) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2007.09.003 · Cited by 582 · see citing works
Misunderstandings in prescribing decisions in general practice: qualitative study
Britten, N. (2000) · BMJ · doi:10.1136/bmj.320.7233.484 · Cited by 454 · see citing works
Improving Acceptance of Computerized Prescribing Alerts in Ambulatory Care
Shah, N. R., Seger, A. C., Seger, D. L., Fiskio, J. M., Kuperman, G. J., Blumenfeld, B., Recklet, E. G., Bates, D. W., & Gandhi, T. K. (2006) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m1868 · Cited by 353 · see citing works
Sheikh, A., Cornford, T., Barber, N., Avery, A., Takian, A., Lichtner, V., Petrakaki, D., Crowe, S., Marsden, K., Robertson, A., et al. (2011) · BMJ · doi:10.1136/bmj.d6054 · Cited by 314 · see citing works
Self-citationBuilding a safer NHS for patients: improving medication safety
Smith, J., & Cavell, G. F. (2004) · Cited by 284 · see citing works
Kesselheim, A. S., Cresswell, K., Phansalkar, S., Bates, D. W., & Sheikh, A. (2011) · Health Affairs · doi:10.1377/hlthaff.2010.1111 · Cited by 277 · see citing works
Self-citationGreenhalgh, T., Stramer, K., Bratan, T., Byrne, E., Russell, J., & Potts, H. W. W. (2010) · BMJ · doi:10.1136/bmj.c3111 · Cited by 275 · see citing works
Schedlbauer, A., Prasad, V., Mulvaney, C., Phansalkar, S., Stanton, W., Bates, D. W., & Avery, A. J. (2009) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m2910 · Cited by 262 · see citing works
Greenhalgh, T., Stramer, K., Bratan, T., Byrne, E., Mohammad, Y., & Russell, J. (2008) · BMJ · doi:10.1136/bmj.a1786 · Cited by 257 · see citing works
Garg, A. X., Adhikari, N. K. J., McDonald, H., Rosas-Arellano, M. P., Devereaux, P. J., Beyene, J., Sam, J., & Haynes, R. B. (2007) · Cited by 253 · see citing works
Hsieh, T. C., Kuperman, G. J., Jaggi, T., Hojnowski-Diaz, P., Fiskio, J., Williams, D. H., Bates, D. W., & Gandhi, T. K. (2004) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m1556 · Cited by 232 · see citing works
Robertson, A., Cresswell, K., Takian, A., Petrakaki, D., Crowe, S., Cornford, T., Barber, N., Avery, A., Fernando, B., Jacklin, A., et al. (2010) · BMJ · doi:10.1136/bmj.c4564 · Cited by 230 · see citing works
Self-citationPhansalkar, S., Edworthy, J., Hellier, E., Seger, D. L., Schedlbauer, A., Avery, A. J., & Bates, D. W. (2010) · Journal of the American Medical Informatics Association · doi:10.1136/jamia.2010.005264 · Cited by 226 · see citing works
Health information exchange and patient safety
Kaelber, D. C., & Bates, D. W. (2007) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2007.08.011 · Cited by 206 · see citing works
Niazkhani, Z., Pirnejad, H., Berg, M., & Aarts, J. (2009) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m2419 · Cited by 203 · see citing works
Pearson, S.-A., Moxey, A., Robertson, J., Hains, I., Williamson, M., Reeve, J., & Newby, D. (2009) · BMC Health Services Research · doi:10.1186/1472-6963-9-154 · Cited by 193 · see citing works
The Impact of CPOE Medication Systems’ Design Aspects on Usability, Workflow and Medication Orders
Jaspers, M., & Khajouei, R. (2009) · Methods of Information in Medicine · doi:10.3414/me0630 · Cited by 187 · see citing works
Does awareness of being video recorded affect doctors' consultation behaviour?
(1990) · PubMed Central · Cited by 186 · see citing works
Using video-recorded consultations for research in primary care: advantages and limitations
Coleman, T. (2000) · Family Practice · doi:10.1093/fampra/17.5.422 · Cited by 169 · see citing works
10. Management of explicit and tacit knowledge
Wyatt, J. C. (2001) · Journal of the Royal Society of Medicine · doi:10.1177/014107680109400102 · Cited by 168 · see citing works
Avery, A., Barber, N., Ghaleb, M. A., Franklin, B. D., Armstrong, S. L., Crowe, S., Dhillon, S., Freyer, A. M., Howard, R., Pezzolesi, C., et al. (2012) · CentAUR (University of Reading) · Cited by 158 · see citing works
Miller, R. A., Waitman, L. R., Chen, S., & Rosenbloom, S. T. (2005) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2005.08.009 · Cited by 144 · see citing works
e-Prescribing, Efficiency, Quality: Lessons from the Computerization of UK Family Practice
Schade, C. P., Sullivan, F., de Lusignan, S., & Madeley, J. (2006) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m2041 · Cited by 113 · see citing works
Fernando, B., Savelyich, B. S. P., Avery, A. J., Sheikh, A., Bainbridge, M., Horsfield, P., & Teasdale, S. (2004) · BMJ · doi:10.1136/bmj.328.7449.1171 · Cited by 70 · see citing works
Self-citationZachariah, M., Phansalkar, S., Seidling, H. M., Neri, P. M., Cresswell, K. M., Duke, J. D., Bloomrosen, M., Volk, L. A., & Bates, D. W. (2011) · Journal of the American Medical Informatics Association · doi:10.1136/amiajnl-2011-000362 · Cited by 53 · see citing works
Self-citationRuss, A. L., Zillich, A. J., McManus, M. S., Doebbeling, B. N., & Saleem, J. J. (2009) · PubMed Central · Cited by 45 · see citing works
Cresswell, K. M., & Sheikh, A. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.12.1180 · Cited by 38 · see citing works
The many faces of the computer: An analysis of clinical software in the primary care consultation
Pearce, C. M., Arnold, M., Phillips, C. B., Trumble, S., & Dwan, K. (2012) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2012.01.004 · Cited by 33 · see citing works
Kaushal, R., Shojania, K. G., & Bates, D. W. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.12.1409 · Cited by 30 · see citing works
Karnon, J., McIntosh, A., Dean, J., Bath, P., Hutchinson, A., Oakley, J., Thomas, N., Pratt, P., Freeman-Parry, L., Karsh, B.-T., et al. (2007) · Safety Science · doi:10.1016/j.ssci.2006.08.026 · Cited by 26 · see citing works
de Lusignan, S., Kumarapeli, P., Chan, T., Pflug, B., van Vlymen, J., Jones, B., & Freeman, G. K. (2008) · Journal of Medical Internet Research · doi:10.2196/jmir.1080 · Cited by 24 · see citing works
The Role of Computerized Decision Support in Reducing Errors in Selecting Medicines for Prescription
Baysari, M. T., Westbrook, J. I., Braithwaite, J., & Day, R. O. (2011) · Drug Safety · doi:10.2165/11588200-000000000-00000 · Cited by 20 · see citing works
Reporting Observational Studies of the Use of Information Technology in the Clinical Consultation
Pearce, C. M., Kumarapeli, P., Stavropoulou, C., Kushniruk, A. W., Sheikh, A., Shachak, A., Mendis, K., & de Lusignan, S. (2011) · Yearbook of Medical Informatics · doi:10.1055/s-0038-1638735 · Cited by 14 · see citing works
Self-citationPflug, B., Kumarapeli, P., van Vlymen, J., Ammenwerth, E., & de Lusignan, S. (2010) · Informatics for Health and Social Care · doi:10.3109/17538150903358693 · Cited by 8 · see citing works
Decision support and patient safety: the time has come
Hasley, S. K. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.10.901 · Cited by 7 · see citing works
Analyzing transaction workflows in an ePrescribing system.
Virk, P., Bates, D. W., Halamka, J. D., et al. (2006) · PubMed · Cited by 4 · see citing works
Decision Support and Patient Safety
HASLEY, S. (2012) · Obstetric Anesthesia Digest · doi:10.1097/01.aoa.0000414066.82440.af · Cited by 4 · see citing works
Avoidable prescribing errors: communication and monitoring
Avery, T. (2010) · Prescriber · doi:10.1002/psb.603 · Cited by 3 · see citing works
Flagged first, then by citations
5 of the 55 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Stroetmann, 2007, eHealth for safety. Impact of ICT on patient safety and risk management
- Safety and Quality Council, 2002, Second national report on patient safety, improving medication safety
- Duerden, 2011, The quality of GP prescribing. An inquiry into the quality of general practice in England
- Davies, 2011, English GP systems market
Cited by
Sorted by citations
Drug interaction alert override rates in the Meaningful Use era: No evidence of progress
Bryant, A. D., Fletcher, G. S., & Payne, T. H. (2014) · Applied Clinical Informatics · doi:10.4338/aci-2013-12-ra-0103 · Cited by 172 · see citing works
Russ, A. L., Zillich, A. J., Melton, B. L., Russell, S. A., Chen, S., Spina, J. R., Weiner, M., Johnson, E., Daggy, J., McManus, M. S., et al. (2014) · Journal of the American Medical Informatics Association · doi:10.1136/amiajnl-2013-002045 · Cited by 136 · see citing works
“Prescribers made fewer errors with the redesigned alerts, shifting the distribution to the left.”
Olakotan, O. O., & Mohd Yusof, M. (2021) · Health Informatics Journal · doi:10.1177/14604582211007536 · Cited by 101 · see citing works
“51,101 96–98 Examples include clinicians waiting for an alert before proceeding to other tasks because of slow processing time, computer crashes, and Internet connectivity problems.”
BackgroundMoja, L., Friz, H. P., Capobussi, M., Kwag, K. H., Banzi, R., Ruggiero, F. M., González‐Lorenzo, M., Liberati, E. G., Mangia, M., Nyberg, P. M., et al. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.17094 · Cited by 68 · see citing works
Jeffries, M., Keers, R. N., Phipps, D. L., Williams, R., Brown, B. C., Avery, A. J., Peek, N. B., & Ashcroft, D. M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205419 · Cited by 66 · see citing works
Self-citationComputer decision support systems for asthma: a systematic review
Matui, P., Wyatt, J. C., Pinnock, H., Sheikh, A., & McLean, S. (2014) · npj Primary Care Respiratory Medicine · doi:10.1038/npjpcrm.2014.5 · Cited by 63 · see citing works
Self-citationTechnology, cognition and error
Coiera, E. W. (2015) · BMJ Quality & Safety · doi:10.1136/bmjqs-2014-003484 · Cited by 48 · see citing works
“20 Catching design errors requires effort during system development, through rich interaction with users and their workplace.”
BackgroundA comparison of potential psychiatric drug interactions from six drug interaction database programs
Monteith, S., & Glenn, T. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.03.041 · Cited by 47 · see citing works
The effect of medication cost transparency alerts on prescriber behavior
Monsen, C. B., Liao, J. M., Gaster, B., Flynn, K. J., & Payne, T. H. (2019) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocz025 · Cited by 43 · see citing works
“One approach to achieve this objective is to provide cost information earlier in prescribing workflow, before a drug has been discussed with the patient, selected, and order details entered.(26) Additionally, the alerts implemented for this study include 1 type of content used to influence behavior—medication costs—an…”
BackgroundFletcher, E., Burns, A., Wiering, B., Lavu, D., Shephard, E., Hamilton, W., Campbell, J. L., & Abel, G. (2023) · BMC Primary Care · doi:10.1186/s12875-023-01973-2 · Cited by 40 · see citing works
Peek, N. B., Gude, W. T., Keers, R. N., Williams, R., Kontopantelis, E., Jeffries, M., Phipps, D. L., Brown, B. C., Avery, A. J., & Ashcroft, D. M. (2020) · PLoS Medicine · doi:10.1371/journal.pmed.1003286 · Cited by 38 · see citing works
Self-citationJeffries, M., Phipps, D. L., Howard, R. L., Avery, A. J., Rodgers, S., & Ashcroft, D. M. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-014810 · Cited by 38 · see citing works
“16 29 Strong structuration theory (SST) has been proposed as a way of examining these sociotechnical aspects of healthcare IT implementation.”
BackgroundJeffries, M., Phipps, D. L., Howard, R. L., Avery, A. J., Rodgers, S., & Ashcroft, D. M. (2017) · BMC Health Services Research · doi:10.1186/s12913-017-2131-5 · Cited by 33 · see citing works
“Consistent with previous literature, participants in our study had adapted work practices to use the EMOS [13, 19].”
BackgroundResultInfluentialCho, I., Slight, S. P., Nanji, K. C., Seger, D. L., Maniam, N., Fiskio, J. M., Dykes, P. C., & Bates, D. W. (2015) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2015.04.006 · Cited by 26 · see citing works
“Several systematic reviews [6, 9, 10] of CDS systems across a range of clinical domains and review studies [3, 11-14] have identified key steps that organizations should take to ensure the successful implementation and maintenance of a CDS system.”
BackgroundReducing Prescribing Errors Through Creatinine Clearance Alert Redesign
Melton, B. L., Zillich, A. J., Russell, S. A., Weiner, M., McManus, M. S., Spina, J. R., & Russ, A. L. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2015.05.033 · Cited by 26 · see citing works
Sinnott, C., Georgiadis, A., Park, J., & Dixon‐Woods, M. (2020) · The Annals of Family Medicine · doi:10.1370/afm.2485 · Cited by 26 · see citing works
Jeffries, M., Gude, W. T., Keers, R. N., Phipps, D. L., Williams, R., Kontopantelis, E., Brown, B. C., Avery, A. J., Peek, N. B., & Ashcroft, D. M. (2020) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-020-1084-5 · Cited by 24 · see citing works
Self-citationChana, N. S., Porat, T., Whittlesea, C., & Delaney, B. C. (2017) · British Journal of General Practice · doi:10.3399/bjgp17x689389 · Cited by 24 · see citing works
“Previous studies have identified concerns from GPs in prescribing specialist drugs and in the use of shared care protocols Difficulties have included lack of awareness or access to either local traffic light classification lists or shared care protocols Furthermore, CDSSs have been reported to appear too late during p…”
BackgroundEvaluation of usage patterns and user perception of the drug–drug interaction database SFINX
Andersson, M. L., Böttiger, Y., Bastholm‐Rahmner, P., et al. (2015) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2015.01.013 · Cited by 23 · see citing works
Cresswell, K. M., Slee, A., Coleman, J. J., Williams, R., Bates, D. W., & Sheikh, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079394 · Cited by 23 · see citing works
Self-citationVideo-based observation research: A systematic review of studies in outpatient health care settings
Golembiewski, E. H., Suárez, N. R. E., Maraboto, A., Yang, A. X., Kunneman, M., Hassett, L. C., & Montori, V. M. (2022) · Patient Education and Counseling · doi:10.1016/j.pec.2022.09.017 · Cited by 21 · see citing works
Veinot, T. C., Senteio, C. R., Hanauer, D. A., & Lowery, J. C. (2017) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocx085 · Cited by 19 · see citing works
“They may be interspersed with other tasks during patient visits.(64) As part of the overall context, information tasks determine the information sources used and the information processing activities that take place.”
BackgroundNassehi, D., Gripsrud, B. H., & Ramvi, E. (2024) · Interactive Journal of Medical Research · doi:10.2196/47280 · Cited by 22 · see citing works
Jeffries, M., Salema, N.-E., Laing, L., Shamsuddin, A., Sheikh, A., Avery, A. J., Chuter, A., Waring, J. J., & Keers, R. N. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250946 · Cited by 19 · see citing works
Self-citationHelldén, A., Al-Aieshy, F., Bastholm‐Rahmner, P., Bergman, U., Gustafsson, L. L., Höök, H., Sjöviker, S., Söderström, A., & Odar‐Cederlöf, I. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-006775 · Cited by 18 · see citing works
“A study of GPs in UK, including video filming, showed that the GP experienced several alerts, for example, on potential allergies and intolerance.(4) Frequent alerts at the end of the consultation process may be unwelcome or disturbing and alert fatigue may follow.”
BackgroundNwafor, O., Ma, X., Johnson, N., Singh, R., & Aron, R. (2023) · Journal of Management Information Systems · doi:10.1080/07421222.2023.2229126 · Cited by 18 · see citing works
“Electronic healthcare record systems refer to software applications used to create, store, and update electronic health records [75].”
MethodMacKenna, B., Bacon, S., Walker, A. J., Curtis, H. J., Croker, R., & Goldacre, B. M. (2020) · Journal of Medical Internet Research · doi:10.2196/17003 · Cited by 16 · see citing works
“One small mixed methods study involving the EMIS EHR system found that only three pop-ups from 117 alerts resulted in the general practitioner checking, but not altering, the prescription [25].”
BackgroundMonteith, S., Glenn, T., Gitlin, M. J., & Bauer, M. (2020) · Pharmacopsychiatry · doi:10.1055/a-1156-4193 · Cited by 17 · see citing works
Jeffries, M., Salema, N.-E., Laing, L., Shamsuddin, A., Sheikh, A., Avery, A. J., Chuter, A., Waring, J. J., & Keers, R. N. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-068798 · Cited by 15 · see citing works
Self-citationCho, I., Lee, J., Choi, S., Choi, J., Hwang, H. Y., & Bates, D. W. (2015) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2015.05.011 · Cited by 14 · see citing works
Spencer, K. L., Absolom, K. L., Allsop, M. J., Relton, S. D., Pearce, J., Liao, K., Naseer, S., Salako, O., Howdon, D., Hewison, J., et al. (2023) · JCO Clinical Cancer Informatics · doi:10.1200/cci.23.00070 · Cited by 12 · see citing works
Hussain, M., Nelson, A. M., Yeung, B., Sukumar, L., & Zheng, K. (2019) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocz213 · Cited by 11 · see citing works
“We hypothesized that the alternative design would increase the appropriateness of physician prescriptions, because it was intended to facilitate “information foraging,”(21) convey information through cognitively efficient graphic representation,(7,38) and deliver CDS early on in the prescribing process.(39) We also hy…”
BackgroundSirota, M., Kostopoulou, O., Round, T., & Samaranayaka, S. (2017) · Health Psychology · doi:10.1037/hea0000461 · Cited by 10 · see citing works
“How long does it take?” A mixed methods evaluation of computer-related work in GP consultations
Hayward, J., Buckingham, S. C., Thomson, F., Milne, H., Sheikh, A., Fernando, B., Cresswell, K. M., Williams, R., & Pinnock, H. (2015) · Journal of Innovation in Health Informatics · doi:10.14236/jhi.v22i4.95 · Cited by 8 · see citing works
Self-citationDesign and Evaluation of Trust–Eliciting Cues in Drug–Drug Interaction Alerts
Chattopadhyay, D., Verma, N., Duke, J. D., & Bolchini, D. P. (2017) · Interacting with Computers · doi:10.1093/iwc/iwx020 · Cited by 5 · see citing works
“Research suggests a binary compliance measure is inadequate because it fails to assess all possible effects of encountering a DDI alert, such as monitoring actions, dosage modifications or provider–patient interactions (Hayward et al., 2013; Russ et al., 2012).”
BackgroundMoynagh, P., Mannion, Á., Wei, A., Clyne, B., Moriarty, F., & McCarthy, C. (2024) · HRB Open Research · doi:10.12688/hrbopenres.13909.1 · Cited by 4 · see citing works
Boonyarattanasoonthorn, T., Khemawoot, P., & Kijtawornrat, A. (2021) · Veterinary Sciences · doi:10.3390/vetsci8040060 · Cited by 3 · see citing works
“Many healthcare providers dislike using drug interaction databases [27] for several reasons, including alert fatigue [28,29], workflow disturbance [30], and belief that there is no clinical significance related to most DDI alerts [31].”
BackgroundLamy, J.-B., Jacques Bouaud, A., & Support, S. E. F. T. I. Y. S. O. D. (2014) · Yearbook of Medical Informatics · doi:10.15265/iy-2014-0036 · Cited by 3 · see citing works
“The third selected paper, by Hayward et al. [15], differs from “classical” studies evaluating CDSSs.”
BackgroundUnderstanding Advice Sharing among Physicians: Towards Trust-Based Clinical Alerts
Chattopadhyay, D., Ghahari, R. R., Duke, J. D., & Bolchini, D. P. (2015) · Interacting with Computers · doi:10.1093/iwc/iwv030 · Cited by 3 · see citing works
“Still, physician adherence remains low, as does satisfaction and trust in clinical alert systems (Hayward et al., 2013; Jung et al., 2013).”
BackgroundEndorsement, Prior Action, and Language
Chattopadhyay, D., Duke, J. D., & Bolchini, D. (2016) · doi:10.1145/2851581.2892315 · Cited by 1 · see citing works
“Overall, physician adherence continues to remain low— and increasingly attributed to a lack of satisfaction and trust in clinical alert systems [9].”
BackgroundComputerized order entry, clinical decision support, and safer prescribing
Pontefract, S. K., & Ferner, R. E. (2017) · Adverse Drug Reaction Bulletin · doi:10.1097/fad.0000000000000026 · Cited by 1 · see citing works
Comparing potential drug-drug interactions in veterinary medications using two electronic databasesPreprint
Boonyarattanasoonthorn, T., Khemawoot, P., & Kijtawornrat, A. (2020) · doi:10.21203/rs.3.rs-23037/v2 · Cited by 1 · see citing works
DRUG-DRUG INTERACTIONS - FROM KNOWLEDGE BASE TO CLINICAL IMPACT
Andersson, M. L. (2014) · Figshare
MEDICAL BENEFIT OF PREEMPTIVE REPORTING OF PHARMACOGENOMIC INFORMATION FROM WHOLE EXOME SEQUENCING
Ball, D. W. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/cagz-7107
Comparing Potential Drug-Drug Interactions in Veterinary Medications Using Two Electronic DatabasesPreprint
Kijtawornrat, A., Boonyarattanasoonthorn, T., & Khemawoot, P. (2020) · doi:10.21203/rs.3.rs-23037/v1
“[20], and feeling that most DDI alerts are unnecessary or clinically irrelevant [21].”
BackgroundRutter, J. (2020) · Wolverhampton Intellectual Repository and E-Theses (University of Wolverhampton)
Physician resilience to computer decision support system-generated alerts (Preprint)Preprint
Piscitelli, A., Auxilia, F., Capobussi, M., et al. (2021) · doi:10.2196/preprints.28908
Moynagh, P., Mannion, Á., Wei, A., et al. (2025) · HRB Open Research · doi:10.12688/hrbopenres.13909.2
“However problems such as interrupting work flow and too many alerts can cause “alert fatigue” resulting in the user ignoring recommendations 12 .”
- Authors
- Hayward, J., Thomson, F., Milne, H., Buckingham, S., Sheikh, A., Fernando, B., Cresswell, K., Williams, R., & Pinnock, H.
- Affiliations
- University of Edinburgh (GB)
- Corresponding author
- Pinnock, Hilary
- Venue
- Journal of the American Medical Informatics Association
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-03-07
- Volume
- 20
- Issue
- e1
- Pages
- e76-e84
- ISSN
- 1067-5027 (ISSN-L)
- 1527-974X
- PMC
- PMC3715350
- OpenAlex
- W2120444843
- Semantic Scholar
- 8f801d09ea4265ea71ec65ae99f3b09d8e8066cb
- Cited by
- 48
- References
- 55
- Citations by year
- 2024: 2 · 2023: 4 · 2022: 1 · 2021: 4 · 2020: 9 · 2019: 5 · 2018: 1 · 2017: 7 · 2016: 1 · 2015: 8 · 2014: 5 · 2013: 1
- FWCI
- 8.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of the American Medical Informatics Association (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Funders
- Scottish Government
- Topics
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Family Practice › Clinical Reasoning and Diagnostic Skills
- Keywords
- computerized decision support systems, drug prescribing, general practitioners, clinical alerts, primary care visits, patient-clinician interaction, drug safety
- MeSH terms
- Drug Therapy, Computer-Assisted, Humans, Physician-Patient Relations, Practice Patterns, Physicians', Task Performance and Analysis, Video Recording, Decision Support Systems, Clinical, Electronic Prescribing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-09.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-09.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review