The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Physical activity and breast cancer risk: impact of timing, type and dose of activity and population subgroup effects
Abstract
Objective: To review (1) the epidemiological literature on physical activity and the risk of breast cancer, examining the effect of the different parameters of activity and effect modification within different population subgroups; and (2) the biological mechanisms whereby physical activity may influence the risk of breast cancer. Methods: A review of all published literature to September 2007 was conducted using online databases; 34 case-control and 28 cohort studies were included. The impact of the different parameters of physical activity on the association between activity and the risk of breast cancer was examined by considering the type of activity performed, the timing of activity over the life course and the intensity of activity. Effect modification of this association by menopausal status, body mass index (BMI), racial group, family history of breast cancer, hormone receptor status, energy intake and parity were also considered. Results: Evidence for a risk reduction associated with increased physical activity was found in 47 (76%) of 62 studies included in this review with an average risk decrease of 25–30%. A dose-response effect existed in 28 of 33 studies. Stronger decreases in risk were observed for recreational activity, lifetime or later life activity, vigorous activity, among postmenopausal women, women with normal BMI, non-white racial groups, those with hormone receptor negative tumours, women without a family history of breast cancer and parous women. Conclusions: The effect of physical activity on the risk of breast cancer is stronger in specific population subgroups and for certain parameters of activity that need to be further explored in future intervention trials.
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Cites
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Physical activity and cancer prevention: etiologic evidence and biological mechanisms
Friedenreich, C. M., & Orenstein, M. R. (2002) · The Journal of Nutrition · doi:10.1093/jn/132.11.3456s · Cited by 699
Self-citationHealy, G. N., Dunstan, D. W., Salmon, J., Cerin, E., Shaw, J. E., Zimmet, P. Z., & Owen, N. (2007) · Diabetes Care · doi:10.2337/dc07-0114 · Cited by 627
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Physical Activity and Breast Cancer: A Systematic Review
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Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
Vona-Davis, L., & Rose, D. P. (2007) · Endocrine-Related Cancer · doi:10.1677/erc-06-0068 · Cited by 496
AMPK, the metabolic syndrome and cancer
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Relation of BMI and physical activity to sex hormones in postmenopausal women
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Energy Availability, Not Body Fatness, Regulates Reproductive Function in Women
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Cited by
Physical activity and survival after breast cancer diagnosis: Meta-analysis of published studies
Ibrahim, E. M., & Al-Homaidh, A. (2011) · Medical Oncology · doi:10.1007/s12032-010-9536-x · Cited by 604
Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth
Hojman, P., Dethlefsen, C., Brandt, C., Hansen, J., Pedersen, L., & Pedersen, B. K. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00520.2010 · Cited by 259
Neilson, H. K., Friedenreich, C. M., Brockton, N. T., & Millikan, R. C. (2009) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0756 · Cited by 232
Self-citationFriedenreich, C. M., Neilson, H. K., Woolcott, C. G., McTiernan, A., Wang, Q., Ballard-Barbash, R., Jones, C. A., Stanczyk, F. Z., Brant, R. F., Yasui, Y., et al. (2011) · Endocrine Related Cancer · doi:10.1530/erc-10-0303 · Cited by 124
Self-citationExercise effects on tumorigenesis in a p53-deficient mouse model of breast cancer
COLBERT, L. H., WESTERLIND, K. C., PERKINS, S. N., HAINES, D. C., BERRIGAN, D., DONEHOWER, L. A., FUCHS-YOUNG, R., & HURSTING, S. D. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31819f1f05 · Cited by 60
Metadata
- Authors
- Friedenreich, C. M., & Cust, A. E.
- Venue
- British Journal of Sports Medicine
- Publisher
- BMJ
- Published
- 2008-05-16
- Volume
- 42
- Issue
- 8
- Pages
- 636-647
- ISSN
- 0306-3674 (ISSN-L)
- 1473-0480
- OpenAlex
- W2081703950
- Cited by
- 345
- References
- 12
- FWCI
- 14.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- Friedenreich, C. M., & Cust, A. E. (2008). Physical activity and breast cancer risk: impact of timing, type and dose of activity and population subgroup effects. British Journal of Sports Medicine. https://doi.org/10.1136/bjsm.2006.029132
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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