Cited by 710Statistical Methods in Clinical TrialsAdvanced Causal Inference TechniquesMeta-analysis and systematic reviews

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Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis

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Fergusson, Dean, Aaron, Shawn D, Guyatt, Gordon, Hébert, Paul·2002·BMJ

DOI 10.1136/bmj.325.7365.652PMC PMC1124168

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Abstract

When is it legitimate to exclude randomised patients from the analysis of data in clinical trials? Basing their analysis on the desirability of minimising bias and random error, the authors consider the circumstances when it may be possible to exclude patients, even in an intention to treat trial

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Authors: Fergusson, D., Aaron, S. D., Guyatt, G., & Hébert, P.
Affiliations: McMaster University (CA)
Corresponding author: Fergusson, Dean
ORCID: Fergusson, Dean
Hébert, Paul
Venue: BMJ
Publisher: BMJ
Published: 2002-09-21
Volume: 325
Issue: 7365
Pages: 652-654
ISSN: 0007-1447 (ISSN-L)
0959-8138
1468-5833
DOI: 10.1136/bmj.325.7365.652
PMC: PMC1124168
OpenAlex: W2000522086
Cited by: 708
References: 19
Citations by year: 2026: 22 · 2025: 26 · 2024: 30 · 2023: 24 · 2022: 46 · 2021: 59 · 2020: 36 · 2019: 37 · 2018: 35 · 2017: 40 · 2016: 34 · 2015: 40 · 2014: 34 · 2013: 27 · 2012: 21
FWCI: 17.26
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.bmj.com/company/legal-information/terms-conditions/legal-information/tdm-licencepolicy (tdm)
Locations: BMJ (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
DigitalGeorgetown (Georgetown University Library) (submittedVersion)
Topics: Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Keywords: intention-to-treat analysis, randomized controlled trials, random error, statistical analysis of clinical trials
MeSH terms: Data Interpretation, Statistical, Humans, Randomized Controlled Trials as Topic, Patient Selection

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Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis

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