Cited by 1,600Statistical Methods in Clinical TrialsMeta-analysis and systematic reviewsMethemoglobinemia and Tumor Lysis Syndrome

The DOI matches its Crossref record; 36 of the 37 references it cites were found in a registry or an index.

Simultaneous comparison of multiple treatments: Combining direct and indirect evidence.

Open access

Caldwell, Deborah M, Ades, A E, Higgins, J P T·2005·BMJ

DOI 10.1136/bmj.331.7521.897PMC PMC1255806

Open this paper in CoChat — free account Open PDF

Abstract

A randomized comparison between rasburicase and allopurinol in children with lymphoma or

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1136/bmj.331.7521.897

Cites

36 of 36 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
Self-citation
Cochrane Handbook for Systematic Reviews of Interventions
Higgins, J. P. T., Green, S., & Ben Van Den, A. (2020) · International Coaching Psychology Review · doi:10.53841/bpsicpr.2020.15.2.123 · Cited by 5,670
Self-citation
Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials
Keeley, E. C., Boura, J., & Grines, C. L. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12113-7 · Cited by 4,339
Clinical guidelines: Potential benefits, limitations, and harms of clinical guidelines
Woolf, S. H., Grol, R. P. T. M., Hutchinson, A., Eccles, M., & Grimshaw, J. (1999) · BMJ · doi:10.1136/bmj.318.7182.527 · Cited by 2,549
Combination of direct and indirect evidence in mixed treatment comparisons
Lu, G., & Ades, A. E. (2004) · Statistics in Medicine · doi:10.1002/sim.1875 · Cited by 2,172
Self-citation
The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials.
Bucher, H. C., Guyatt, G. H., Griffith, L. E., & Walter, S. D. (1997) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(97)00049-8 · Cited by 2,052
Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis
Paty, D. W., Li, D. K. B., the UBC MS/MRI Study Group, & the IFNB Multiple Sclerosis Study Group (1993) · Neurology · doi:10.1212/wnl.43.4.662 · Cited by 1,964
Systematic Reviews: Rationale for systematic reviews
Mulrow, C. D. (1994) · BMJ · doi:10.1136/bmj.309.6954.597 · Cited by 1,677
Network meta‐analysis for indirect treatment comparisons
Lumley, T. (2002) · Statistics in Medicine · doi:10.1002/sim.1201 · Cited by 1,206
Health Outcomes Associated With Various Antihypertensive Therapies Used as First-Line Agents
Psaty, B. M., Lumley, T., Furberg, C. D., Lovasi, G. S., Pahor, M., Alderman, M. H., & Weiss, N. S. (2003) · JAMA · doi:10.1001/jama.289.19.2534 · Cited by 1,096

Flagged first, then by citations

Show all 37 references

1 of the 37 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

Spiegelhalter DJ, Myles JP, Jones DR, Abrams K. An introduction to Baye- sian methods in health technology assessment. BMJ 1999;319:508-12.

Sorted by citations

Items 601–700 of 1,003

Model Averaging in the Presence of Structural Uncertainty about Treatment Effects: Influence on Treatment Decision and Expected Value of Information
Price, M. J., Welton, N. J., Briggs, A. H., & Ades, A. E. (2011) · Value in Health · doi:10.1016/j.jval.2010.08.001 · Cited by 33
“Third, it should respect the randomisation structure in the evidence, combining where necessary randomized evidence on pair-wise comparisons to make inferences about relative efficacy of several treatments [25,27].”
BackgroundSelf-citation
Parameterization of treatment effects for meta‐analysis in multi‐state Markov models
Price, M. J., Welton, N. J., & Ades, A. E. (2010) · Statistics in Medicine · doi:10.1002/sim.4059 · Cited by 33
“This model is then used for a Bayesian MTC to estimate marginal posterior distributions for the relative efficacies of the different treatments.”
BackgroundMethodInfluentialSelf-citation
Efficacy and Acceptability of Glycemic Control of Glucagon-Like Peptide-1 Receptor Agonists among Type 2 Diabetes: A Systematic Review and Network Meta-Analysis
Li, Z., Zhang, Y., Quan, X., Yang, Z., Zeng, X., Ji, L., Sun, F., & Zhan, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154206 · Cited by 33
“Network meta-analysis has been proved to be the most appropriate method for multiple treatments comparison to date [26, 129].”
Method
The Importance of Considering Differences in Study Design in Network Meta-analysis: An Application Using Anti-Tumor Necrosis Factor Drugs for Ulcerative Colitis
Cameron, C. G., Ewara, E. M., Wilson, F. R., Varu, A., Dyrda, P., Hutton, B., & Ingham, M. (2017) · Medical Decision Making · doi:10.1177/0272989x17711933 · Cited by 32
“However, before conducting an indirect comparison or NMA, it is important to assess heterogeneity between trials in terms of patient characteristics and study design to determine if it is appropriate to combine the results of multiple trials into one analysis.(1) The appropriate use of NMAs can lead to enhanced decisi…”
Method
Bartlett‐type corrections and bootstrap adjustments of likelihood‐based inference methods for network meta‐analysis
Noma, H., Nagashima, K., Maruo, K., Gosho, M., & Furukawa, T. A. (2017) · Statistics in Medicine · doi:10.1002/sim.7578 · Cited by 34
“One limitation when evaluating the efficacy of a particular treatment of interest in conventional meta‐analysis is that such methods can only be applied to direct pairwise comparison evidence.(1) To overcome this limitation, network meta‐analysis has been developed to enable the comprehensive synthesis and simultaneou…”
Controlled ovarian stimulation protocols for assisted reproduction: a network meta-analysis
Gallos, I. D., Eapen, A. K., Price, M. J., Sunkara, S. K., Macklon, N., Bhattacharya, S., Khalaf, Y., Tobı́as, A., Deeks, J. J., Rajkhowa, M., et al. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012586 · Cited by 32
Digital Interventions for Generalized Anxiety Disorder (GAD): Systematic Review and Network Meta-Analysis
Saramago, P., Gega, L., Marshall, D. C., Nikolaidis, G. F., Janković, D., Melton, H., Dawson, S., Churchill, R. C., & Bojke, L. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.726222 · Cited by 33
“Data Synthesis and Statistical Analysis Over the last two decades, network meta-analysis (NMA) methods (17) also known as mixed treatment comparisons (18, 19)–have been developed to synthesize evidence from multiple studies.”
Method
Comparative efficacy and acceptability of pharmacotherapeutic agents for anxiety disorders in children and adolescents: a mixed treatment comparison meta-analysis
Uthman, O. A., & Abdulmalik, J. O. (2009) · Current Medical Research and Opinion · doi:10.1185/03007990903416853 · Cited by 33
Treatments for relapsing–remitting multiple sclerosis: summarising current information by network meta-analysis
Santo, F. D., Maratea, D., Fadda, V., Trippoli, S., & Messori, A. (2011) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-011-1141-1 · Cited by 31
A network meta-analysis of antibiotics for treatment of hospitalised patients with suspected or proven meticillin-resistant Staphylococcus aureus infection
Bally, M., Dendukuri, N., Sinclair, A., Ahern, S. P., Poisson, M., & Brophy, J. M. (2012) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2012.08.004 · Cited by 29
“[14] Caldwell DM, Ades AE, Higgins JP.”
BackgroundMethod
A network meta-analysis of randomized controlled trials for comparing the effectiveness and safety profile of treatments with marketing authorization for relapsing multiple sclerosis
Hadjigeorgiou, G. M., Doxani, C., Miligkos, M., Ziakas, P. D., Bakalos, G., Papadimitriou, D. A., Mprotsis, T., Grigoriadis, N., & Zintzaras, E. (2013) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/jcpt.12090 · Cited by 31
Lung ventilation strategies for acute respiratory distress syndrome: a systematic review and network meta-analysis
Wang, C., Wang, X., Chi, C., Guo, L., Guo, L., Zhao, N., Wang, W., Pi, X., Sun, B., Lian, A., et al. (2016) · Scientific Reports · doi:10.1038/srep22855 · Cited by 32
Multimodality treatment of locally advanced squamous cell carcinoma of the oesophagus: A comprehensive review and network meta-analysis
Montagnani, F., Fornaro, L., Frumento, P., Vivaldi, C., Falcone, A., & Fioretto, L. (2017) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2017.03.024 · Cited by 31
Efficacy and Safety of Induction Therapy in Kidney Transplantation: A Network Meta-Analysis
Hwang, S. D., Lee, J. H., Lee, S. W., Park, K.-M., Kim, J. K., Kim, M.-J., & Song, J. (2018) · Transplantation Proceedings · doi:10.1016/j.transproceed.2018.01.022 · Cited by 31
Evaluation of cost-effectiveness among open, laparoscopic and robotic distal pancreatectomy: A systematic review and meta-analysis
Partelli, S., Ricci, C., Cinelli, L., Montorsi, R. M., Ingaldi, C., Andreasi, V., Crippa, S., Alberici, L., Casadei, R., & Falconi, M. (2021) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2021.03.066 · Cited by 31
Progestogens for preventing miscarriage: a network meta-analysis
Devall, A., Papadopoulou, A., Haas, D. M., Price, M. J., Coomarasamy, A., & Gallos, I. D. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013792 · Cited by 31
Paracetamol, NSAIDS and opioid analgesics for chronic low back pain: a network meta-analysis
Bagg, M. K., McLachlan, A. J., Maher, C. G., Kamper, S. J., Williams, C. M., Henschke, N., Wand, B. M., Moseley, G. L., Hübscher, M., O'Connell, N. E., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013045 · Cited by 32
“NMA uses the ‘direct’ clinical trial data to ‘indirectly’ estimate the effects for the missing comparisons (blank edges) (Caldwell 2005; Cipriani 2009; Jansen 2011; Jansen 2013; Mills 2013; Song 2003; Sutton 2008).”
Method
Comparative efficacy and safety of warfarin care bundles and novel oral anticoagulants in patients with atrial fibrillation: a systematic review and network meta-analysis
Ng, S. S., Lai, N. M., Nathisuwan, S., Jahan, N. K., Dilokthornsakul, P., Kongpakwattana, K., Hollingworth, W., & Chaiyakunapruk, N. (2020) · Scientific Reports · doi:10.1038/s41598-019-57370-2 · Cited by 30
Physical Prehabilitation in Patients who Underwent Major Abdominal Surgery: A Comprehensive Systematic Review and Component Network Meta-Analysis Using GRADE and CINeMA Approach
Ricci, C., Alberici, L., Serbassi, F., Caraceni, P., Domenicali, M., Ingaldi, C., Grego, D. G., Mazzucchelli, C., & Casadei, R. (2023) · Annals of Surgical Oncology · doi:10.1245/s10434-023-14632-8 · Cited by 37
“21,22 The variety of interventions was considered among the best if p -score was ≥0.66; when p -score was 0.65 to 0.33, the combination was judged inferior to the best/better than the worst; when p -score was <0.33, the combination was considered among the worst.”
MethodInfluential
An Economic Evaluation of Short-Acting Opioids for Treatment of Breakthrough Pain in Patients with Cancer
Vissers, D. C. J., Lenre, M., Tolley, K. H., Jakobsson, J., Sendersky, V., & Jansen, J. P. (2011) · Value in Health · doi:10.1016/j.jval.2010.09.007 · Cited by 30
Treatment Comparisons for Decision Making: Facing the Problems of Sparse and Few Data
Soares, M. O., Dumville, J. C., Ades, A. E., & Welton, N. J. (2013) · Journal of the Royal Statistical Society Series A (Statistics in Society) · doi:10.1111/rssa.12010 · Cited by 30
“For each model, the treatments of interest were ranked by using the posterior probabilities that each of these treatments is the most effective (Caldwell et al., 2005).”
MethodSelf-citation
Polyethylene glycol vs. sodium phosphate for bowel preparation: A treatment arm meta-analysis of randomized controlled trials
Juluri, R., Eckert, G. J., & Imperiale, T. F. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-38 · Cited by 30
“While head-to-head meta-analysis and network meta-analysis of the same data have been compared [88], there are no comparative analyses between network and treatment-arm meta-analyses.”
Method
Acupuncture-Related Techniques for Psoriasis: A Systematic Review with Pairwise and Network Meta-Analyses of Randomized Controlled Trials
Yeh, M., Ko, S., Wang, M.-H., Chi, C., & Chung, Y.-C. (2017) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2016.0158 · Cited by 30
A Bayesian Hierarchical Summary Receiver Operating Characteristic Model for Network Meta-Analysis of Diagnostic Tests
Lian, Q., Hodges, J. S., & Chu, H. (2018) · Journal of the American Statistical Association · doi:10.1080/01621459.2018.1476239 · Cited by 31
“To address these limitations and challenges, and motivated by the literature on network meta-analysis of randomized clinical trials (Caldwell, Ades, and Higgins 2005; Lu and Ades 2006; Mills et al. 2012; Zhang et al. 2014), we present a Bayesian hierarchical summary receiver operating…”
Method
Periodontal Regenerative Therapy for Preventing Bone Defects Distal to Mandibular Second Molars After Surgical Removal of Impacted Third Molars: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Camps‐Font, O., Caro-Bonfill, C., Sánchez‐Garcés, M. Á., & Gay‐Escoda, C. (2018) · Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.joms.2018.07.025 · Cited by 30
Surgical approaches for treatment of ureteropelvic junction obstruction – a systematic review and network meta-analysis
Uhlig, A., Uhlig, J., Trojan, L., Hinterthaner, M., von Hammerstein-Equord, A. F., & Strauß, A. (2019) · BMC Urology · doi:10.1186/s12894-019-0544-7 · Cited by 31
Progress and challenges of network meta‐analysis
Tian, J., Gao, Y., Zhang, J., Yang, Z., Dong, S., Zhang, T., Sun, F., Wu, S., Wu, J., Wang, J., et al. (2021) · Journal of Evidence-Based Medicine · doi:10.1111/jebm.12443 · Cited by 29
Evidence for the cardiovascular effects of osteoporosis treatments in randomized trials of post-menopausal women: A systematic review and Bayesian network meta-analysis
Seeto, A. H., Tadrous, M., Gebre, A. K., Lewis, J. R., Fink, H. A., Ebeling, P. R., & Rodríguez, A. J. (2022) · Bone · doi:10.1016/j.bone.2022.116610 · Cited by 31
The relative efficacy of imatinib, dasatinib and nilotinib for newly diagnosed chronic myeloid leukemia: a systematic review and network meta-analysis
Mealing, S., Barcena, L., Hawkins, N., Clark, J. F., Eaton, V., Hirji, I., & Davis, C. (2013) · Experimental Hematology and Oncology · doi:10.1186/2162-3619-2-5 · Cited by 30
“Indirect comparison (network) meta-analysis is an extension of conventional, pair-wise meta-analysis [21-25].”
Mindfulness-based 'third wave' cognitive and behavioural therapies versus other psychological therapies for depression
Hunot, V., Moore, T. H., Caldwell, D., Davies, P., Jones, H., Lewis, G., & Churchill, R. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008704 · Cited by 29
Self-citation
Comparative outcomes of heart failure among existent classes of anti-diabetic agents: a network meta-analysis of 171,253 participants from 91 randomized controlled trials
Yang, D.-Y. D., He, X., Liang, H., Zhang, S., Zhong, X., Luo, C., Du, Z., He, J., Zhuang, X., & Liao, X. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0853-x · Cited by 29
Network meta‐analysis of longitudinal data using fractional polynomials
Jansen, J. P., Vieira, M.-C., & Cope, S. F. (2015) · Statistics in Medicine · doi:10.1002/sim.6492 · Cited by 29
Effect of Biologic Agents on Non-PASI Outcomes in Moderate-to-Severe Plaque Psoriasis: Systematic Review and Meta-Analyses
Baker, E. L., Coleman, C. I., Reinhart, K. M., Phung, O. J., Kugelman, L., Chen, W., White, C. M., Mamolo, C. M., Cappelleri, J. C., & Baker, W. L. (2012) · Dermatology and Therapy · doi:10.1007/s13555-012-0009-3 · Cited by 29
“In addition to traditional meta-analysis, a MTC meta-analysis was conducted using previously validated WinBUGS code [18–22].”
Method
Evaluation of Antiplatelet Agents for Secondary Prevention of Stroke Using Mixed Treatment Comparison Meta-analysis
Malloy, R. J., Kanaan, A. O., Silva, M. A., & Donovan, J. L. (2013) · Clinical Therapeutics · doi:10.1016/j.clinthera.2013.09.004 · Cited by 30
Efficacy and safety of selective COX-2 inhibitors for pain management after third molar removal: a meta-analysis of randomized clinical trials
González‐Barnadas, A., Camps‐Font, O., Martín‐Fatás, P., Figueiredo, R., Gay‐Escoda, C., & Valmaseda‐Castellón, E. (2019) · Clinical Oral Investigations · doi:10.1007/s00784-019-02910-3 · Cited by 32
Role of immune checkpoint inhibitor-based therapies for metastatic renal cell carcinoma in the first-line setting: A Bayesian network analysis
Wang, J., Li, X., Wu, X., Wang, Z., Zhang, C., Cao, G., Zhang, X., Peng, F., & Yan, T. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.08.006 · Cited by 30
Systematic review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP): study protocol
Seidler, A. L., Duley, L., Katheria, A. C., Matallana, C. D. P., Dempsey, E. M., Rabe, H., Kattwinkel, J., Mercer, J., Josephsen, J. B., Fairchild, K. D., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-034595 · Cited by 29
Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis
Gibbs, V. N., Champaneria, R., Sandercock, J., Welton, N. J., Geneen, L. J., Brunskill, S. J., Doree, C. J., Kimber, C., Palmer, A. J. R., & Estcourt, L. J. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013295.pub2 · Cited by 28
When Conventional Heart Failure Therapy is Not Enough: Angiotensin Receptor Blocker, Direct Renin Inhibitor, or Aldosterone Antagonist?
Bangalore, S., Kumar, S., & Messerli, F. H. (2012) · Congestive Heart Failure · doi:10.1111/chf.12011 · Cited by 29
Synthesis of Evidence On Heterogeneous Interventions with Multiple Outcomes Recorded Over Multiple Follow-Up Times Reported Inconsistently: A Smoking Cessation Case-Study
Madan, J. J., Chen, Y., Aveyard, P. N., Wang, D., Yahaya, I., Munafo, M. R., Bauld, L., & Welton, N. J. (2013) · Journal of the Royal Statistical Society Series A (Statistics in Society) · doi:10.1111/rssa.12018 · Cited by 28
“NMA extends pairwise meta-analysis to situations where there is a network of comparisons over three or more interventions (Caldwell et al., 2005; Lu and Ades, 2004) and allows greater flexibility than standard pairwise approaches when analysing complex evidence structures (Cooper et al.”
Background
An exploration of synthesis methods in public health evaluations of interventions concludes that the use of modern statistical methods would be beneficial
Achana, F. A., Hubbard, S., Sutton, A. J., Kendrick, D., & Cooper, N. J. (2014) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2013.09.018 · Cited by 29
Comparative effectiveness of antibiotics for uncomplicated urinary tract infections: Network meta-analysis of randomized trials
Knottnerus, B. J., Grigoryan, L., Geerlings, S. E., van Charante, E. P. M., Verheij, T. J., Kessels, A. G. H., & ter Riet, G. (2012) · Family Practice · doi:10.1093/fampra/cms029 · Cited by 29
Efficacy and safety of botulinum toxin injection for interstitial cystitis/bladder pain syndrome: a systematic review and meta-analysis
Shim, S. R., Cho, Y. J., Shin, I., & Kim, J. H. (2016) · International Urology and Nephrology · doi:10.1007/s11255-016-1295-y · Cited by 29
“Indirect evidence should be cautiously applied in clinical practice as it is usually considered less reliable than direct evidence [34, 35].”
Background
Systematic Review and Network Meta-Analysis of Overall Survival Comparing 3 mg/kg Ipilimumab With Alternative Therapies in the Management of Pretreated Patients With Unresectable Stage III or IV Melanoma
Dequen, P., Lorigan, P. C., Jansen, J. P., van Baardewijk, M., Ouwens, M., & Kotapati, S. (2012) · The Oncologist · doi:10.1634/theoncologist.2011-0427 · Cited by 27
“In the absence of head-to-head efficacy comparisons beyond the gp100 vaccine, an indirect treatment comparison, or network meta-analysis (NMA), is a powerful methodology to compare results with ipilimumab with published results of current or previously used therapies for advanced melanoma [19–27].”
Result
Evidence-Based Prescribing
Naci, H., van Valkenhoef, G., Higgins, J. P. T., Fleurence, R., & Ades, A. E. (2014) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.114.000825 · Cited by 28
Self-citation
Comparison of the efficacy and tolerability of tocilizumab, sarilumab, and sirukumab in patients with active rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials
Bae, S., & Lee, Y. H. (2018) · Clinical Rheumatology · doi:10.1007/s10067-018-4006-5 · Cited by 28
“We used the Markov chain Monte Carlo method to obtain the pooled effect sizes [29].”
Method
Effects of oral antidiabetic drugs and glucagon-like peptide-1 receptor agonists on left ventricular diastolic function in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
Ida, S., Kaneko, R., Imataka, K., Ôkubo, K., Shirakura, Y., Azuma, K., Fujiwara, R., Takahashi, H., & Murata, K. (2020) · Heart Failure Reviews · doi:10.1007/s10741-020-09936-w · Cited by 28
Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network
Freeman, S. C., Cooper, N. J., Sutton, A. J., Crowther, M. J., Carpenter, J. R., & Hawkins, N. (2022) · Statistical Methods in Medical Research · doi:10.1177/09622802211070253 · Cited by 29
Comparative efficacy and safety of different combinations of three CDK4/6 inhibitors with endocrine therapies in HR+/HER-2 − metastatic or advanced breast cancer patients: a network meta-analysis
Liu, Y., Wu, J., Ji, Z., Chen, L., Zou, J., Zheng, J., Lin, W., Cai, J., Chen, Y., Zheng, D., et al. (2023) · BMC Cancer · doi:10.1186/s12885-023-11322-2 · Cited by 29
“Bayesian network meta-analysis was performed using R software (V.4.1.1) and the “gemtc” package [30–32] through Markov Chain Monte Carlo (MCMC) simulation.”
MethodInfluential
Pharmacological treatments in panic disorder in adults: a network meta-analysis
Guaiana, G., Meader, N., Barbui, C., Davies, S., Furukawa, T. A., Imai, H., Dias, S., Caldwell, D. M., Koesters, M., Tajika, A., et al. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012729.pub3 · Cited by 35
Self-citation
Crossing the fourth hurdle
Rawlins, M. D. (2012) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04263.x · Cited by 28
Treatment Comparison in Rheumatoid Arthritis: Head-to-Head Trials and Innovative Study Designs
Favalli, E. G., Bugatti, S., Biggioggero, M., & Caporali, R. F. (2014) · BioMed Research International · doi:10.1155/2014/831603 · Cited by 28
“Furthermore, multiple different pairwise comparisons across a range of different interventions can be combined into network meta-analysis (also known as mixed treatment comparisons or multiple treatment meta-analyses) [58, 59].”
Background
A first step to assess harm and benefit in clinical trials in one scale
Boers, M., Brooks, P., Fries, J. F., Simon, L. S., Strand, V., & Tugwell, P. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.07.002 · Cited by 28
Relative Survival Benefit and Morbidity with Fluids in Severe Sepsis - A Network Meta-Analysis of Alternative Therapies
Bansal, M., Farrugia, A., Balboni, S., & Martin, G. S. (2013) · Current Drug Safety · doi:10.2174/15748863113089990046 · Cited by 28
“Network meta-analytic techniques have recently been developed that estimate the relative efficacy of any number of different treatments by taking account of the entire network of RCT evidence [24-26].”
Comparative effectiveness of glycemic control in patients with type 2 diabetes treated with GLP-1 receptor agonists: a network meta-analysis of placebo-controlled and active-comparator trials
Orme, M. E., Nguyen, H. P., Lu, J., & Thomas, S. V. (2017) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s116810 · Cited by 27
Respiratory training interventions improve health status of heart failure patients: A systematic review and network meta-analysis of randomized controlled trails
Wang, M.-H., & Yeh, M. (2019) · World Journal of Clinical Cases · doi:10.12998/wjcc.v7.i18.2760 · Cited by 27
Comparative efficacy of antimicrobial treatments in dairy cows at dry-off to prevent new intramammary infections during the dry period or clinical mastitis during early lactation: a systematic review and network meta-analysis
Winder, C. B., Sargeant, J. M., Hu, D., Wang, C., Kelton, D. F., LeBlanc, S. J., Duffield, T. F., Glanville, J., Wood, H., Churchill, K. J., et al. (2019) · Animal Health Research Reviews · doi:10.1017/s1466252319000239 · Cited by 27
“Network meta-analysis provides a method of assessing relative efficacy among many treatments by the use of both direct (studies which compare given treatments) and indirect (studies which share common comparators) evidence, and is a commonly used approach in human medicine (Caldwell et al., 2005; Cipriani et al., 2013…”
Method
Treatments for infantile Hemangioma: A systematic review and network meta-analysis
Fei, Q., Lin, Y., & Chen, X. (2020) · EClinicalMedicine · doi:10.1016/j.eclinm.2020.100506 · Cited by 31
“The application of network meta-analysis (NMA), which is able to synthesize the results of direct and indirect comparisons simultaneously to obtain a more accurate and precise statistical result, makes it possible to overcome the limitation [6].”
Method
Systematic review and network meta-analysis of the efficacy of existing treatments for patients with recurrent glioblastoma
Schritz, A., Aouali, N., Fischer, A., Dessenne, C., Adams, R., Berchem, G., Huiart, L., & Schmitz, S. (2021) · Neuro-Oncology Advances · doi:10.1093/noajnl/vdab052 · Cited by 27
A Bayesian network meta-analysis regarding the comparative efficacy of therapeutics for ALK-positive, brain metastatic non-small cell lung cancer
Zhao, B., Han, Y., Wang, Y., Wang, Y., Wang, Y., Xing, H., Dai, C., Wang, Y., Wang, H., & Ma, W. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105931 · Cited by 27
Selecting the best scale for measuring treatment effect in a network meta‐analysis: a case study in childhood nocturnal enuresis
Caldwell, D. M., Welton, N. J., Dias, S., & Ades, A. E. (2012) · Research Synthesis Methods · doi:10.1002/jrsm.1040 · Cited by 27
“Network meta-analysis (Higgins and Whitehead, 1996; Lu and Ades, 2004; Caldwell et al., 2005; Salanti et al., 2008), also termed mixed treatment comparisons, refers to ensembles of trial evidence in which direct and indirect evidence on relative treatment effects are pooled.”
BackgroundSelf-citation
Homophily and co-occurrence patterns shape randomized trials agendas: illustration in antifungal agents
Rizos, E. C., Salanti, G., Kontoyiannis, D. P., & Ioannidis, J. P. A. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.11.017 · Cited by 28
“017 efforts in this direction [1,2].”
Testing moderation in network meta‐analysis with individual participant data
Dagne, G. A., Brown, C. H., Howe, G. W., Kellam, S. G., & Liu, L. (2016) · Statistics in Medicine · doi:10.1002/sim.6883 · Cited by 28
Identifying back pain subgroups: developing and applying approaches using individual patient data collected within clinical trials
Patel, S., Hee, S. W., Mistry, D., Jordan, J., Brown, S., Dritsaki, M., Ellard, D. R., Friede, T., Lamb, S. E., Lord, J. L., et al. (2016) · Programme Grants for Applied Research · doi:10.3310/pgfar04100 · Cited by 26
“C trials), even if no B versus C trials exist.(175) NWMA has become increasing popular in decision-making contexts because choosing among more than two treatments requires all pairwise treatment effects to be consistent in this way (the true treatment effects in the decision problem will always be consistent(176,177)).”
Background
Cost‐effectiveness of psychological interventions for children and young people with post‐traumatic stress disorder
Mavranezouli, I., Megnin‐Viggars, O., Trickey, D., Meiser‐Stedman, R., Daly, C., Dias, S., Stockton, S., & Pilling, S. (2019) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13142 · Cited by 27
Network meta-analysis and pharmacoeconomic evaluation of antibiotics for the treatment of patients infected with complicated skin and soft structure infection and hospital-acquired or ventilator-associated penumonia
Zhang, Y., Wang, Y., van Driel, M., McGuire, T., Zhang, T., Dong, Y., Liu, Y., Liu, L., Hao, R., Cao, L., et al. (2019) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-019-0518-2 · Cited by 27
Multiple comparisons of the efficacy and safety for six treatments in Acute Achilles Tendon Rupture patients: A systematic review and network meta-analysis
Shi, F., Wu, S., Cai, W., & Zhao, Y.-M. (2020) · Foot and Ankle Surgery · doi:10.1016/j.fas.2020.07.004 · Cited by 26
Antidepressants for pain management in adults with chronic pain: a network meta-analysis
Birkinshaw, H., Friedrich, C., Cole, P., Eccleston, C., Serfaty, M. A., Stewart, G. B., White, S. J., Moore, A., & Pincus, T. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd014682 · Cited by 28
Comparative efficacy of non-statin lipid-lowering therapies in patients with hypercholesterolemia at increased cardiovascular risk: a network meta-analysis
Burnett, H. F., Fahrbach, K. R., Cichewicz, A. B., Jindal, R., Tarpey, J., Durand, A., Domenico, M. D., Reichelt, A., & Viljoen, A. (2022) · Current Medical Research and Opinion · doi:10.1080/03007995.2022.2049164 · Cited by 32
Comparative Effectiveness of Rituximab and Common Induction Therapies for Lupus Nephritis: A Systematic Review and Network Meta-Analysis
Li, K., Yu, Y., Gao, Y., Zhao, F., Liang, Z., & Gao, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.859380 · Cited by 26
Graphical exploration of network meta-analysis data: the use of multidimensional scaling
Chung, H., & Lumley, T. (2008) · Clinical Trials · doi:10.1177/1740774508093614 · Cited by 26
“If a network is incoherent in terms of transitivity of treatment effects, inference based on indirect comparisons may not be useful [7,8].”
Background
How to Promote Bedside Placement of the Postpyloric Feeding Tube
Tiancha, H., Jiyong, J., & Yan, M. (2014) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114546166 · Cited by 26
Safety and immunogenicity of prepandemic H5N1 influenza vaccines: A systematic review of the literature
Prieto-Lara, E., & Llanos-Méndez, A. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.03.068 · Cited by 26
Drug treatment of macular oedema secondary to central retinal vein occlusion: a network meta-analysis
Ford, J. A., Shyangdan, D., Uthman, O. A., Lois, N., & Waugh, N. R. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-005292 · Cited by 26
Critical Issues on the Use of Network Meta-analysis in Psychiatry
Yıldız, A., Vieta, E., Correll, C. U., Nikodem, M., & Baldessarini, R. J. (2014) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000025 · Cited by 26
Comparing antibiotic treatment for leptospirosis using network meta-analysis: a tutorial
Naing, C. M., Reid, S. A., & Aung, K. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-016-2145-3 · Cited by 26
“As such, a conventional pairwise meta-analysis may be conducted, but the comparative effectiveness of all available interventions for a given condition will not be addressed [3].”
Background
Comparison of up-front treatments for newly diagnosed immune thrombocytopenia -a systematic review and network meta-analysis
Arai, Y., Jo, T., Matsui, H., Kondo, T., & Takaori‐Kondo, A. (2017) · Haematologica · doi:10.3324/haematol.2017.174615 · Cited by 25
Evaluation of the efficacy and safety of sarilumab combination therapy in patients with rheumatoid arthritis with inadequate response to conventional disease-modifying antirheumatic drugs or tumour necrosis factor α inhibitors: systematic literature review and network meta-analyses
Choy, E., Freemantle, N., Proudfoot, C., Chen, C.-I., Pollissard, L., Kuznik, A., van Hoogstraten, H., Mangan, E. K., Carita, P., & Huynh, T.-M.-T. (2019) · RMD Open · doi:10.1136/rmdopen-2018-000798 · Cited by 26
Publication bias and small-study effects magnified effectiveness of antipsychotics but their relative ranking remained invariant
Mavridis, D., Efthimiou, O., Leucht, S., & Salanti, G. (2015) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2015.05.027 · Cited by 24
Intraoperative mechanical ventilation strategies for obese patients: a systematic review and network meta‐analysis
Wang, C., Zhao, N., Wang, W., Guo, L., Guo, L., Chi, C., Wang, X., Pi, X., Cui, Y., & Li, E. (2015) · Obesity Reviews · doi:10.1111/obr.12274 · Cited by 26
“Network meta-analysis permits evaluating the comparative effectiveness of multiple interventions, even when some pairs may not have been directly compared, and has the potential to reduce the uncertainty in treatment effect estimates (8,9).”
Background
Clinical outcomes associated with drugs for obesity and overweight: A systematic review and network meta‐analysis of randomized controlled trials
Iannone, A., Natale, P., Palmer, S. C., Nicolucci, A., Rendina, M., Giorgino, F., Laviola, L., Di Leo, A., & Strippoli, G. F. M. (2023) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.15138 · Cited by 27
“Frequentist network meta-analysis was then performed to compare available treatment strategies within a single analytical framework.(19,20) For each network, the extent of heterogeneity was assessed using the maximum likelihood method.”
Method
Management of cognitive frailty: A network meta‐analysis of randomized controlled trials
Zhang, Y., Zhou, J., Zhang, X., Liu, J., Li, M., Liang, J., & Gao, Y. (2023) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5994 · Cited by 26
“22 This enables more precise estimations of the relative effects between any pair of interventions, as well as effect size ‐ based ranking of the interventions.”
Cost-Effectiveness of Combination Nonbiologic Disease-Modifying Antirheumatic Drug Strategies in Patients with Early Rheumatoid Arthritis
Tosh, J. C., Wailoo, A., Scott, D. L., & Deighton, C. (2011) · The Journal of Rheumatology · doi:10.3899/jrheum.101327 · Cited by 25
Indirect comparison of clobazam and other therapies for Lennox-Gastaut syndrome
Cramer, J. A., Sapin, C., & François, C. (2013) · Acta Neurologica Scandinavica · doi:10.1111/ane.12086 · Cited by 25
“Alternative approaches, such as mixedtreatment comparisons or pairwise indirect comparisons (used in this review), permit indirect comparisons of drugs when no direct comparative evidence from individual clinical studies are available (28, 29).”
Síntesis de la evidencia clínica y metaanálisis en red con comparaciones indirectas
Catalá-López, F., & Tobı́as, A. (2012) · Medicina Clínica · doi:10.1016/j.medcli.2012.09.013 · Cited by 25
Interventionen zur Resilienzförderung bei Erwachsenen
Linz, S., Helmreich, I., Kunzler, A. M., Chmitorz, A., Lieb, K., & Kubiak, T. (2019) · PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie · doi:10.1055/a-0830-4745 · Cited by 27
“Anwendungen von Netzwerk-Metaanalysen, mit denen direkte und indirekte Evidenz erfasst und verglichen werden kann [99, 100]), in diesem Bereich zu verbessern.”
Background
Treatment for Infected Pancreatic Necrosis Should be Delayed, Possibly Avoiding an Open Surgical Approach
Ricci, C., Pagano, N., Ingaldi, C., Frazzoni, L., Migliori, M., Alberici, L., Minni, F., & Casadei, R. (2020) · Annals of Surgery · doi:10.1097/sla.0000000000003767 · Cited by 26
Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis
Ahmadzai, N., Cheng, W., Kilty, S., Esmaeilisaraji, L., Wolfe, D. M., Bonaparte, J. P., Schramm, D., Fitzpatrick, E. M., Lin, V. W., Skidmore, B., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0237523 · Cited by 28
The place of vericiguat in the landscape of treatment for heart failure with reduced ejection fraction
Aimo, A., Castiglione, V., Vergaro, G., Panichella, G., Senni, M., Lombardi, C., & Emdin, M. (2021) · Heart Failure Reviews · doi:10.1007/s10741-021-10146-1 · Cited by 25
The Efficacy and Safety of Pharmacological Treatments for Restless Legs Syndrome: Systemic Review and Network Meta-Analysis
Zhou, X., Du, J., Liang, Y., Dai, C., Zhao, L., Liu, X., Tan, C., Mo, L., & Chen, L. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.751643 · Cited by 29
EMG biofeedback combined with rehabilitation training may be the best physical therapy for improving upper limb motor function and relieving pain in patients with the post-stroke shoulder-hand syndrome: A Bayesian network meta-analysis
Feng, S., Tang, M., Huang, G., Wang, J., He, S., Liu, D., & Gu, L. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2022.1056156 · Cited by 32
Post-thyroidectomy complications. The role of the device: bipolar vs ultrasonic device
Palma, M. D., Rosato, L., Zingone, F., Orlando, G., Antonino, A., Vitale, M., & Puzziello, A. (2015) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2015.05.024 · Cited by 25
Development of a Transparent Interactive Decision Interrogator to Facilitate the Decision-Making Process in Health Care
Bujkiewicz, S., Jones, H. E., Lai, M. C. W., Cooper, N. J., Hawkins, N., Squires, H., Abrams, K. R., Spiegelhalter, D. J., & Sutton, A. J. (2011) · Value in Health · doi:10.1016/j.jval.2010.12.002 · Cited by 25
Network Analysis of Randomized Controlled Trials in Multiple Sclerosis
Zintzaras, E., Doxani, C., Mprotsis, T., Schmid, C. H., & Hadjigeorgiou, G. M. (2012) · Clinical Therapeutics · doi:10.1016/j.clinthera.2012.02.018 · Cited by 25
Neurokinin-1 inhibitors in the prevention of nausea and vomiting from highly emetogenic chemotherapy: a network meta-analysis
Abdel-Rahman, O. M. (2016) · Therapeutic Advances in Medical Oncology · doi:10.1177/1758834016654902 · Cited by 25
Therapeutic options for adult patients with previously treated immune thrombocytopenia – a systematic review and network meta-analysis
Yang, R., Lin, L., Yao, H., Ji, O., & Shen, Q. (2019) · Hematology · doi:10.1080/16078454.2019.1568659 · Cited by 25
“We posited that this limitation can be overcome by performing a network meta-analysis [8], which unlike a pairwise meta-analysis, allows researchers to combine”
Background
Knowledge Synthesis in Evidence-Based Medicine
Garritty, C., Stevens, A., Hamel, C., Golfam, M., Hutton, B., & Wolfe, D. M. (2019) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2018.11.006 · Cited by 26
A comparison of regorafenib and fruquintinib for metastatic colorectal cancer: a systematic review and network meta-analysis
Zhu, J., Zhou, R., & binglan, Z. (2019) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-019-02964-6 · Cited by 26
Effects of 9 oral care solutions on the prevention of oral mucositis: a network meta-analysis of randomized controlled trials
Yu, Y.-T., Deng, J., Jin, X.-R., Zhang, Z.-Z., Zhang, X., & Zhou, X. (2020) · Medicine · doi:10.1097/md.0000000000019661 · Cited by 24
Indirect comparison of the effects of anti-TNF biological agents in patients with Ankylosing Spondylitis by means of a Mixed Treatment Comparison performed on efficacy data from published randomised, controlled trials
Migliore, A., Broccoli, S., Bizzi, E., & Laganà, B. (2012) · Journal of Medical Economics · doi:10.3111/13696998.2012.660255 · Cited by 24

Authors: Caldwell, D. M., Ades, A. E., & Higgins, J. P. T.
Affiliations: University of Bristol (GB)
MRC Biostatistics Unit (GB)
Corresponding author: Caldwell, Deborah M
ORCID: Caldwell, Deborah M
Ades, A E
Higgins, J P T
Venue: BMJ
Publisher: BMJ
Published: 2005-10-13
Volume: 331
Issue: 7521
Pages: 897-900
ISSN: 0007-1447 (ISSN-L)
0959-8138
1468-5833
DOI: 10.1136/bmj.331.7521.897
PMC: PMC1255806
OpenAlex: W1967385770
Cited by: 1,600
References: 37
Citations by year: 2026: 53 · 2025: 63 · 2024: 72 · 2023: 67 · 2022: 91 · 2021: 105 · 2020: 136 · 2019: 115 · 2018: 115 · 2017: 108 · 2016: 95 · 2015: 107 · 2014: 101 · 2013: 79 · 2012: 80
FWCI: 16.23
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.bmj.org/licenses/tdm/1.0/terms-and-conditions.html (tdm)
Locations: BMJ (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Explore Bristol Research (submittedVersion)
Topics: Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Health Sciences › Medicine › Hematology › Methemoglobinemia and Tumor Lysis Syndrome
Keywords: rasburicase, allopurinol, hyperuricemia, lymphoma, pediatric oncology, direct and indirect evidence, treatment comparison
MeSH terms: Data Interpretation, Statistical, Decision Making, Humans, Meta-Analysis as Topic, Bias, Randomized Controlled Trials as Topic, Evidence-Based Medicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Simultaneous comparison of multiple treatments: Combining direct and indirect evidence.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks