Adequacy and reporting of allocation concealment: review of recent trials published in four general medical journals
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guidelines.This carelessness sets a poor example for authors.
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The method of randomization was described in only 25% of published RCTs.
“For example, the method of randomization was described in only 25 % of published RCTs [10, 15, 22]”
From Impact of an online writing aid tool for writing a randomized trial report: the COBWEB (Consort-based WEB tool) randomized controlled trial (2015) · cites this paper as [22]
The Methods and results section reports that the allocation-concealment method was unclear in 61 of 234 trials (26%). The Comments section likewise says that about a quarter failed to describe how allocation was concealed—not that only a quarter described the method of randomization. The paper distinguishes allocation concealment from the randomization process and does not report the claimed 25% figure for randomization methods. (LLM, conf=0.87)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredPoor randomisation methods with no concealment can lead to exaggerated treatment effects.
“Poor randomisation methods with no concealment can lead to exaggerated treatment effects,79 80 which can then lead to further problems with overexaggerated systematic reviews.81”
From Novel ACT-based eHealth psychoeducational intervention for students with mental distress: A study protocol for a mixed-methodology pilot trial (2019) · cites this paper as [80]
The Methods and results section reports that trials with inadequate allocation concealment tended to yield statistically significant results more often than trials with adequate concealment; the Comments section reiterates that association. The paper compares P values, not the size of treatment effects, so it does not establish that poor concealment exaggerates treatment effects. (LLM, conf=0.84)
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Chung, W., Lee, K. W., Hwang, I. H., Lee, D. H., & Kim, S. Y. (2009) · Korean Journal of Family Medicine · doi:10.4082/kjfm.2009.30.8.626 · Cited by 15 · see citing works
Hewitt, C. E., Torgerson, D. J., & Berger, V. W. (2008) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2008.06.005 · Cited by 14 · see citing works
Self-citationMethodological Reporting of Randomized Clinical Trials in Respiratory Research in 2010
Lü, Y., Yao, Q., Gu, J., & Shen, C. (2013) · Respiratory Care · doi:10.4187/respcare.01877 · Cited by 14 · see citing works
The JID Opens Its Doors to High-Quality Randomized Controlled Clinical Trials
Williams, H. C., & Goldsmith, L. A. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700467 · Cited by 14 · see citing works
The Role of Neurosurgery Journals in Evidence-Based Neurosurgical Care
Amadio, J. P., & Oyesiku, N. M. (2014) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2014.11.001 · Cited by 14 · see citing works
Torgerson, C. J., Torgerson, D. J., & Taylor, C. A. (2015) · doi:10.1002/9781119171386.ch7 · Cited by 14 · see citing works
Self-citation
- Authors
- Hewitt, C., Hahn, S., Torgerson, D. J., Watson, J., & Bland, J. M.
- Affiliations
- University of York (GB)
- Seoul National University Hospital (KR)
- Corresponding author
- Hewitt, Catherine
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2005-03-10
- Volume
- 330
- Issue
- 7499
- Pages
- 1057-1058
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- PMC
- PMC557225
- OpenAlex
- W2074842559
- Cited by
- 176
- References
- 5
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 8 · 2020: 5 · 2019: 22 · 2018: 5 · 2017: 4 · 2016: 8 · 2015: 14 · 2014: 10 · 2013: 21 · 2012: 11
- FWCI
- 12.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Social Sciences › Decision Sciences › Information Systems and Management › Academic Publishing and Open Access
- Keywords
- allocation concealment, randomization, trial reporting, reporting guidelines, general medical journals
- MeSH terms
- Periodicals as Topic, Random Allocation, Randomized Controlled Trials as Topic
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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